200,392 research outputs found
Ah! lucky Jim, how I envy him [first line of chorus]
No full textstrophic with choruspiano and voiceads on inside back and on back covers for M. Witmark & Sons stockJohns Hopkins University, Levy Sheet Music Collection, Box
142, Item 014Words by Chas. Horwitz. Music by Fredrick V. Bowers
Ah! lucky Jim, how I envy him [first line of chorus]
No full textstrophic with choruspiano and voiceads on inside back and on back covers for M. Witmark & Sons stockJohns Hopkins University, Levy Sheet Music Collection, Box
142, Item 014Words by Chas. Horwitz. Music by Fredrick V. Bowers
Getting beneath the skin to understand MSC complexity
No full textSince their initial description, mesenchymal progenitors have exhibited two general functions: to directly generate tissue by differentiation and to support the survival and proliferation of other cells/tissues by secreting cytokines or growth factors. This dual-function paradigm was represented in the original description of mesenchymal progenitors, now designated as marrow stromal cells (MSC), by their capacity to give rise to bone cells and to support hematopoiesis in vitro
Optimizing the niche conditions for maximal stem cell engraftment: human and animal model data
No full textWhile animal models are ideal to uncover the biologic basis of pathologic observations and therapeutic interventions, whether such scientific findings, in reality, apply to patients is always an open question. The exceptional human data of Zweegman et al corroborate our murine findings and suggest that the novel mechanisms we describe may, in fact, apply to clinical hematopoietic cell transplantation
How do mesenchymal stromal cells exert their therapeutic benefit?
No full textn recent years mesenchymal stromal cells (MSC) have emerged as a major new form of cell therapy. While the original perception was that MSC were stem/progenitor cells with the potential to contribute to the regeneration of tissue, more recent data suggest that the principal mechanism of MSC activity is through the release of soluble mediators that elicit the observed biologic response. Future studies are needed to identify more completely the spectrum of therapeutic applications and delineate better the associated molecular and cellular mechanisms
Anderson_LOH
No full textSimultaneous brain cell type and lineage determined by scRNA-seq reveals
stereotyped cortical developmen
A simple method for the primary isolation of Mycobacterium in a carbon dioxide atmosphere
No full textCITATION: Horwitz, B. M. & Gultig, R. 1974. A simple method for the primary isolation of Mycobacterium in a carbon dioxide atmosphere. South African Medical Journal, 48(46):1949-1950.The original publication is available at http://www.samj.org.zaA simple, inexpensive method which provides increased CO2 tension for the primary isolation of mycobacteria is described. Using this technique, the primary isolation of mycobacteria from 1114 specimens of sputum, gastric washings, spinal fluids, etc. was increased by 24.2%.Publisher’s versio
UD students honored with Horwitz/Horowitz Award for undergraduate research in physiology
No full textTwo UD students received 2022 Barbara A. Horwitz and John M. Horowitz Undergraduate Research Awards from the American Physiological Society
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A new TB vaccine
No full textAlthough M. tuberculosis was identified as an agent of infectious disease by Koch in 1884, it has proved difficult to produce a safe and effective vaccine against it. In this article, Marcus A. Horwitz explains the need to replace the BCG vaccine, outlines the search for new vaccine designs, and points the way to the likely future of TB vaccines
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