1,637 research outputs found

    State-Space Inference and Learning with Gaussian Processes

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    18.10.13 KB. Ok to add author version to spiral, authors hold copyright.State-space inference and learning with Gaussian processes (GPs) is an unsolved problem. We propose a new, general methodology for inference and learning in nonlinear state-space models that are described probabilistically by non-parametric GP models. We apply the expectation maximization algorithm to iterate between inference in the latent state-space and learning the parameters of the underlying GP dynamics model. Copyright 2010 by the authors

    Approche socio-sémiotique du catalogue d’exposition numérique Edward Hopper. D’une fenêtre à l’autre

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    International audienceL'étude du catalogue numérique Edward Hopper. D'une fenêtre à l'autre, édité et publié en 2012, sous la forme d'une application pour iPad, nous a permis d'élaborer les principales briques d'un vocabulaire d'analyse du livre d'art numérique. Central dans notre projet de recherche, le catalogue Hopper occupe une place à part dans l'offre éditoriale de la Réunion des musées nationaux (Rmn-GP), actuel « leader sur le marché des applications d'art »

    Approche socio-sémiotique du catalogue d’exposition numérique Edward Hopper. D’une fenêtre à l’autre

    No full text
    International audienceL'étude du catalogue numérique Edward Hopper. D'une fenêtre à l'autre, édité et publié en 2012, sous la forme d'une application pour iPad, nous a permis d'élaborer les principales briques d'un vocabulaire d'analyse du livre d'art numérique. Central dans notre projet de recherche, le catalogue Hopper occupe une place à part dans l'offre éditoriale de la Réunion des musées nationaux (Rmn-GP), actuel « leader sur le marché des applications d'art »

    Approche socio-sémiotique du catalogue d’exposition numérique Edward Hopper. D’une fenêtre à l’autre

    No full text
    International audienceL'étude du catalogue numérique Edward Hopper. D'une fenêtre à l'autre, édité et publié en 2012, sous la forme d'une application pour iPad, nous a permis d'élaborer les principales briques d'un vocabulaire d'analyse du livre d'art numérique. Central dans notre projet de recherche, le catalogue Hopper occupe une place à part dans l'offre éditoriale de la Réunion des musées nationaux (Rmn-GP), actuel « leader sur le marché des applications d'art »

    The role of actor-networks in the diffusion of management accounting innovations: a comparative study of budgetary control, GP method and Activity-Based Costing in France

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    This research is concerned with the diffusion of management accounting innovations viewed as a process of actor-network building and translation. The aim is to better understand the nature of accounting change. Using Actor-Network Theory (ANT), we analyze two innovations that have had different fates in France. These innovations are the Georges Perrin method (GPM) and Activity-Based Costing (ABC). We are particularly concerned with the dynamic of actor-networks throughout the diffusion processes of these innovations. We show how problematization, interessement, enrolment and mobilization take many, and often very surprising, forms for diffusion to occur.Innovation ; Actor-Network Theory ; Diffusion ; Translation ; ABC ; GP method

    Patient use of an online triage platform : a mixed-methods retrospective exploration in UK primary care

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    Background Recent years have seen the introduction of online triage allowing patients to describe their problem via an online form. Subsequently, a GP telephones the patient, conducting a telephone consultation or arranging a face-to-face consultation. Aim This study aimed to explore patterns-of-use and patients’ experiences of using an online triage system. Design and setting This retrospective study analysed routinely collected data (from all practices using the ‘askmyGP’ platform for the duration of the study period, 19 May 2017 to 31 July 2017), using both quantitative and qualitative approaches. Data originated from an online triaging platform used by patients in nine general practices across the UK. Method Data from 5447 patients were quantitatively analysed to describe characteristics of users, patterns-of-use, and reasons given by patients for using the platform. Free-text comments left by patients (n = 569) on their experience of use were qualitatively analysed. Results Highest levels of use were observed in females (65.5%, n = 3570) and those aged 25–34 years. Patterns of use were high between 0800 and 0959, and on Mondays and Tuesdays. Use outside of GP practice opening hours was low. Common reasons for using the platform were for medication-related enquiries, for administrative requests, and to report a specific symptom. Comments left by patients suggested advantages to using the platform, for example, convenience and the written format, but these did not extend to all users. Conclusion Patterns-of-use and patient types were in line with typical contacts to GP practices. Though the age of users was broad, highest levels of use were from younger patients. The perceived advantages to using online triage, such as convenience and ease of use, are often context dependent

    Systematic Reconstruction of Molecular Cascades Regulating GP Development Using Single-Cell RNA-Seq

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    SummaryThe growth plate (GP) comprising sequentially differentiated cell layers is a critical structure for bone elongation and regeneration. Although several key regulators in GP development have been identified using genetic perturbation, systematic understanding is still limited. Here, we used single-cell RNA-sequencing (RNA-seq) to determine the gene expression profiles of 217 single cells from GPs and developed a bioinformatics pipeline named Sinova to de novo reconstruct physiological GP development in both temporal and spatial high resolution. Our unsupervised model not only confirmed prior knowledge, but also enabled the systematic discovery of genes, potential signal pathways, and surface markers CD9/CD200 to precisely depict development. Sinova further identified the effective combination of transcriptional factors (TFs) that regulates GP maturation, and the result was validated using an in vitro EGFP-Col10a screening system. Our case systematically reconstructed molecular cascades in GP development through single-cell profiling, and the bioinformatics pipeline is applicable to other developmental processes.Video Abstrac

    Performances of authorial presence and absence : the author dies hard

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    This book takes Roland Barthes’s famous proclamation of ‘The Death of the Author’ as a starting point to investigate concepts of authorial presence and absence on various levels of text and performance. By offering a new understanding of ‘the author’ as neither a source of unquestioned authority nor an obsolete construct, but rather as a performative figure, the book illuminates wide-ranging aesthetic and political aspects of ‘authorial death’ by asking: how is the author constructed through cultural and political imaginaries and erasures, intertextual and intertheatrical references, re-performances and self-referentiality? And what are the politics and ethics of these constructions

    Vliv Moto GP na cestovní ruch v Brně

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    The main aim of the bachelor thesis is find out how Moto GP influence tourism in Brno, what is the availability of accommodation facilities, what is the increase in prices during this period. In the theoretical part, analyse the tourism as a whole, destination of tourism, Moto GP. Practical part examines using a questionnaire how residents perceive the action Moto GP. There is unfortunately not sufficient statistical data to determine the icrease in prices as well as occupancy of acommodation capacities in the period when Moto GP race takes place in Brno. That is the reason why the author of this thesis has decided to conduct a research by using a sample of 10 % of hotels in Brno to be able to answer these questions

    Danger in discharge summaries: abbreviations create confusion for both author and recipient

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    Background: The transition from hospital inpatient care to medical care in the community is a high-risk period for adverse events. Inadequate communication, including low-quality or unavailable discharge summaries, has been shown to impact patient care. Aims: To assess use of abbreviations in clinical handover documents from inpatient hospital teams to general practitioners (GP), and the interpretation of these abbreviations by GP and hospital-based junior doctors. Methods: This is a retrospective audit of 802 discharge summaries completed during a 1-week period in 2017 by a Queensland regional health service. GP and local junior doctors then attempted interpretation of 20 relevant abbreviations. Results: A total of 99% (794) discharge summaries included abbreviations. A total of 1612 different abbreviations was used on 16 327 occasions. The median number of abbreviations per discharge summary was 17 (range 0–86). A total of 254 GP and 62 junior doctors responded to a survey, which found that no abbreviation was interpreted the same by all respondents. GP and junior doctors were unable to offer any interpretation in 17.9% and 15.2% of cases respectively. GP offered a greater range of interpretations than junior doctors, with a median of 9 and 3 different interpretations per abbreviation respectively. A total of 94% (239) of GP felt that the use of abbreviations in discharge summaries had the potential to impact patient care. A total of 152 (60%) GP felt that time spent clarifying abbreviations in discharge summaries could be excessive. Conclusions: Abbreviations are often used in discharge summaries, yet poorly understood. This has the potential to impact patient care in the transition period after hospitalisation.No Full Tex
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