17 research outputs found
The use of interdisciplinary seminars for the development of caring dispositions in nursing and social work students
No full textAuthor name used in this publication: Amy Ho Po-yingAuthor name used in this publication: Jenny Hui Man-chun2009-2010 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishedPublisher permissio
Characterization of two acetyltransferase genes in the pyripyropene biosynthetic gene cluster from Penicillium coprobium
No full textPyripyropenes potently and selectively inhibit acyl-CoA:cholesterol acyltransferase 2 (ACAT-2). Among multiple isomers of pyripyropene (A to R), pyripyropene A (PyA) has insecticidal properties in addition to its growth inhibition properties against human umbilical vein endothelial cells. Based on the predicted biosynthetic gene cluster of pyripyropene A, two genes (ppb8 and ppb9) encoding two acetyltransferases (ATs) were separately isolated and introduced into the model fungus Aspergillus oryzae, using the protoplast-polyethylene glycol method. The bioconversion of certain predicted intermediates in the transformants revealed the manner by which acetylation occurred in the biosynthetic pathway by the products expressed by these two genes (AT-1 and AT-2). The acetylated products detected by high-performance liquid chromatography (HPLC) in the extracts from AT-1 and AT-2 transformant clones were not present in the extract from the transformant clone with an empty vector. The HLPC charts of each bioconversion study exhibited high peaks at 12, 10.5 and 9min, respectively. Further ultraviolet absorption and mass spectrometry analyses identified the products as PyE, PyO and PyA, respectively. AT-1 acetylated the C-1 of deacetyl-pyripyropene E (deAc-PyE), while AT-2 played an active role in acetylating the C-11 of 11-deAc-PyO and C-7 of deAc-PyA at two different steps of the biosynthetic pathway.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000348870100006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Biotechnology & Applied MicrobiologySCI(E)[email protected]
Yaşlı Ayrımcılığı ve Mesleki Değerler Arasındaki İlişki: Hemşirelik Öğrencileri Örneği
No full textBu araştırma, hemşirelik öğrencilerinin yaşlılara yönelik tutumları ile mesleki değerleri arasındaki ilişkiyi ve etkileyebilecek faktörleri belirlemek amacıyla yapılmıştır. Tanımlayıcı-ilişki arayıcı tipte yapılan araştırmanın evrenini bir üniversitenin hemşirelik bölümünde öğrenim gören 543 hemşirelik öğrencisi, örneklemini ise 231 öğrenci oluşturmuştur. Veri toplama formu olarak Öğrenci Bilgi Formu, Pozitif ve Negatif Yaşlı Ayrımcılığı Ölçeği (PNYAÖ) ve Hemşirelerin Mesleki Değerleri Ölçeği-Revize (HMDÖ-R) kullanılmıştır. Veriler sayı, yüzde, ortalama, standart sapma, Mann Whitney U Testi, Student’s t Testi, Kruskal Wallis Testi, Tek Yönlü Varyans Analizi (ANOVA) ve korelasyon analizi ile değerlendirildi. Hemşirelik öğrencilerinin PNYAÖ toplam puan ortalamasının 85.75±8.20, PYA ve NYA alt boyut puan ortalamalarının sırası ile 47.24±5.17 ve 21.48±5.43, HMDÖ-R toplam puan ortalamalarının 104.86+15.98 olduğu belirlenmiştir. Öğrencilerin PNYAÖ toplam puan ortalamaları ile cinsiyet ve mezuniyet sonrası yaşlılarla çalışmayı isteme durumları ile arasında; HMDÖ-R puan ortalamaları ile sınıfları arasında istatistiksel olarak anlamlı farklılık bulunmuştur (p<0.05). Öğrencilerin HMDÖ-R puan ortalamaları ile PNYAÖ ve PYA alt boyut puan ortalamaları arasında pozitif yönlü, NYA alt boyut puan ortalamaları arasında ise negatif yönlü istatistiksel olarak anlamlı farklılık bulunmuştur (p<0.05). Hemşirelik öğrencilerin yaşlı bireylere yönelik olumlu bir tutum sergilediği ve mesleki değerlerinin iyi düzeyde olduğu belirlenmiştir. Mesleki değerler düzeyi arttıkça yaşlıya yönelik pozitif ayrımcılığın arttığı ve negatif ayrımcılığın azaldığı saptanmıştır. Dünya çapında hızla artan yaşlı nüfusu göz önünde bulundurularak, hemşirelerin yaşlılar hakkında olumlu algı ve tutum geliştirmelerini sağlamak önemlidir
Microsatellite polymorphism in promoter of heme oxygenase-1 gene is associated with susceptibility to coronary artery disease in type 2 diabetic patients
No full text[[abstract]]Heme oxygenase is a rate-limiting enzyme in heme degradation, leading to the generation of free iron, biliverdin, and carbon monoxide. Induction of heme oxygenase-1 is implicated in the antioxidant defense mechanism and can modulate vascular function. To test the association of microsatellite polymorphism in the promoter region of human HO-1 gene with the risk of coronary artery disease (CAD) in type 2 diabetic patients, we examined the allele frequencies of (GT)(n), repeats in HO-1 gene in 474 patients with CAD and in 322 controls. A transient-transfection assay with HO-1 promoter/luciferase fusion constructs carrying various lengths of (GT), repeats was performed to explore the regulatory effect of (GT),, repeats on HO-1 gene expression in cultured rat aortic smooth muscle cells. Serum thiobarbituric acid-reactive substances (TBARs), a measure of lipid peroxidation, was significantly higher in subjects carrying the L/L genotype (greater than or equal to32 repeats). Among type 2 diabetic subjects, the frequencies of the L alleles and proportion of genotypes with L alleles were significantly higher in those with CAD than in those without CAD. The adjusted odds ratio for CAD in type 2 diabetic patients with L alleles was 4.7 (95% confidence interval, 1.9-12.0, P=0.001). Transfection experiments in aortic smooth muscle cells revealed that HO-1 promoter/luciferase fusion constructs containing longer (GT),, repeats exhibited lower transcriptional activity. These results imply that the length polymorphism in the HO-1 gene promoter modulate the transcription of the gene in vascular cells. Type 2 diabetics carrying longer (GT),, repeats might have higher oxidative stress and increased susceptibility to the development of CAD
Melting of PCM in a thermal energy storage unit: Numerical investigation and effect of nanoparticle enhancement
No full textThe present paper describes the analysis of the melting process in a single vertical shell-and-tube latent heat thermal energy storage (LHTES), unit and it is directed at understanding the thermal performance of the system. The study is realized using a computational fluid-dynamic (CFD) model that takes into account of the phase-change phenomenon by means of the enthalpy method. Fluid flow is fully resolved in the liquid phase-change material (PCM) in order to elucidate the role of natural convection. The unsteady evolution of the melting front and the velocity and temperature fields is detailed. Temperature profiles are analyzed and compared with experimental data available in the literature. Other relevant quantities are also monitored, including energy stored and heat flux exchanged between PCM and HTF. The results demonstrate that natural convection within PCM and inlet HTF temperature significantly affects the phase-change process. Thermal enhancement through the dispersion of highly conductive nanoparticles in the base PCM is considered in the second part of the paper. Thermal behavior of the LHTES unit charged with nano-enhanced PCM is numerically analyzed and compared with the original system configuration. Due to increase of thermal conductivity, augmented thermal performance is observed: melting time is reduced of 15% when nano-enhanced PCM with particle volume fraction of 4% is adopted. Similar improvements of the heat transfer rate are also detecte
The economic effects of minimum import prices : with an application to Uruguay
No full textBy increasing the costs of imports, minimum unit import reference prices not only generate the usual distortions one expects from tariff protection but add new ones that a pure tariff system would not generate. Reference prices substantially reduce the price gap between imports with prices above and below the reference price. By making cheap imports relatively more expensive than expensive imports, reference prices affect quality in three ways that appear not to have been analyzed before: 1) they can induce foreign firms to shift toward more expensive exports to the country with reference prices; 2) they can induce domestic producers in that country to shift production toward lower-quality, cheaper goods; and 3) because this decreases the relative price of the expensive varieties, domestic consumers may lean toward buying more expensive goods. Using the case of Uruguay, the authors estimate what protection the reference price procedures provide for Uruguayan industries and analyze how this protection affects Uruguay's economy. The authors show that the reference and minimum export price procedures impose floor prices on imports that cover more than a third of value added in Uruguayan manufacturing. These systems jeopardize trade liberalization efforts by creating the impression that tariff cuts are greater than they really are. These systems also create massive distortions between the relative domestic prices of imported goods above and below the floor prices.Environmental Economics&Policies,TF054105-DONOR FUNDED OPERATION ADMINISTRATION FEE INCOME AND EXPENSE ACCOUNT,Economic Theory&Research,Markets and Market Access,Access to Markets
Rare earth hydroxycinnamates and hydroxycinnamate-derivative complexes as corrosion inhibitors
No full textThis thesis describes the synthesis and characterisation of rare earth n-hydroxycinnamate (n-
HOc), 3-(n`-hydroxyphenyl)propionate (n-hpp) and (E)-3-(n`-pyridyl)acrylate (n-pya)
complexes (n = 2-4). The corrosion inhibition properties for mild steel in an aqueous
environment are assessed for a selection of these complexes, representative of each of the
ligand systems.
In Chapter 2, a crystal structure for the complex [Ce(4HOc)4(H2O)(MeOH)2].(MeOH) was
determined. The compounds La(4HOc)3(H2O)4, Pr(4HOc)3(H2O)3 and Pr(4HOc)3(H2O)4 were
also obtained complementing the rare earth-4HOc complexes previously prepared. Powder
XRD, analysis together with elemental analysis and TGA analysis of these compounds
indicate that their structural profile are independent from the extents of hydration. In
accordance with the aim of this study to investigate the influence of the hydroxy-substitution
position on the cinnamates, two further series of rare earth complexes, namely with 3-
hydroxycinnamate and 2-hydroxycinnamate ligands were also prepared. The
[RE(3HOc)3(H2O)n].x(H2O) (RE = La and Ce, n = 2, x = 0.5; RE = Pr-Nd, Gd, Er, and Y, n =
1, x = 1) complexes were analogous (based on unit cell data and powder XRD analysis) across the RE elements except Lu2(3HOc)5(OH)(H2O)6 which showed slight differences in the powder XRD. A ferric compound was also obtained, Fe2(3HOc)3(OH)3(H2O)2, and is the only non-rare earth compound in the thesis. The RE-2HOc compounds obtained can be grouped as follows, (Group I) [Ln(2HOc)3(H2O)].2(MeOH) (RE = La and Pr), (Group II)
Ce(2HOc)3(H2O)5.5, (Group III) [Pr2(2HOc)5(OH)(H2O)2].4(H2O), (Group IV)
Ln(2HOc)3(H2O)3, (Group V) [Gd(2HOc)3(solv)2]2.x(solv) (solv = MeOH and/or H2O; x = 0
or 6) and [Er(2HOc)3(H2O)2]2.10(H2O), and (Group VI) [RE(2HOc)3(H2O)2]2.x(solv) (RE =
Gd, x(solv) = 2H2O, 4MeOH; RE = Er, x(solv) = 10H2O; RE = Y, x(solv) = 2H2O). Three
crystal structures were determined for this series of complexes,
[RE(2HOc)3(MeOH)2]2.x(MeOH) (RE = Gd, x = 6; RE = Er, x = 5) (Group V), and
[Er(2HOc)3(H2O)2]2.10(H2O) (Group VI).
Chapter 3 contains a first report for the exciting new RE 3-(n`-hydroxyphenyl)propionate
complexes (n = 2 and 4). This chapter investigates the influence on the structural chemistry of the RE complexes when the the –CH=CH– linker in the carboxylate ligand is reduced to a
flexible –CH2–CH2– linker. The lanthanoid contraction is evident across the RE-4hpp and
RE-2hpp complex series. There are two types of RE-4hpp (RE = La, Ce-Nd, Ho and Lu)
complexes showing six different structural motifs across the series. Type I is monometallic with the complexes [La4(4hpp)12(H2O)6].4(H2O), [Ce(4hpp)3(H2O)][Ce(4hpp)3(H2O)2].(H2O).2.5(EtOH), [Ho(4hpp)3(H2O)2] and
[Lu(4hpp)3].(H2O). The Type II complexes, [NaRE2(4hpp)7(H2O)2].3(H2O) (RE = Ce and Pr)
and [NaNd2(4hpp)7(H2O)(MeOH)].(H2O).3(MeOH), are bimetallic. Five structural motifs are
observed for the RE-2hpp (RE = La, Ce-Pr, Gd and Lu) complexes with the general
composition [RE(2hpp)3(H2O)n].(H2O) (RE = Ce and Pr, n = 1; RE = La, Gd and Lu, n = 2).
A second lutetium complex, [Lu2(2hpp)6(H2O)4].[Lu(2hpp)3(H2O)2].9(H2O).(MeOH) was also identified.
The effect of the replacement of the phenyl-ring of the hydroxycinnamates by a pyridyl-ring is reported in Chapter 4. The [RE(4pya)3(H2O)2].x(solv) (RE = La, Pr, Sm and Y; solv = H2O/MeOH) complexes and [Lu(4pya)3(MeOH)2].3(H2O) complex are obtained. For the RE- 2pya series, the complexes [RE(2pya)3(H2O)2].x(H2O) (RE = La, Pr and Sm) and [RE(2pya)3].2(H2O) (RE = Ho and Lu) were obtained. Two PrIII crystal structures were determined for the complexes [Pr(4pya)3(H2O)2].(H2O).(MeOH) and
[Pr(2pya)3(H2O)2].4(H2O). The latter complexes have never been reported before.
Finally, Chapter 5 involves the screening of selected rare earth carboxylate complexes
reported in Chapters 2, 3 and 4 for their corrosion inhibition properties for mild steel in 0.01
M NaCl solution. Immersion tests were carried out as initial screenings and electrochemical measurements were also made. The effect of the different derivatisation of the hydroxycinnamate ligand in the rare earth complexes was investigated. The La(3HOc)3(H2O)4 complex was determined to have the best performance. The combined data obtained from the immersion tests and electrochemical measurements found that the –CH=CH– linker and the hydroxyphenyl-ring are essential functionalities for effective corrosion mitigation by the rare earth hydroxycinnamate-type complexes
Research progress on sexual functioning and associated factors in childhood cancer survivors : a scoping review
No full text202504 bcrcVersion of RecordSelf-fundedPublishedC
Spelling correction in the NLP system 'LOLITA: dictionary organisation and search algorithms
No full textThis thesis describes the design and implementation of a spelling correction system and associated dictionaries, for the Natural Language Processing System 'LOLITA'. The dictionary storage is based upon a trie (M-ary tree) data-structure. The design of the dictionary is described, and the way in which the data-structure is implemented is also discussed. The spelling correction system makes use of the trie structure in order to limit repetition and "garden path' searching. The spelling correction algorithms used are a variation on the 'reverse minimum edit-distance' technique. These algorithms have been modified in order to place more emphasis on generation in order of likelihood. The system will correct up to two simple errors {i.e. insertion, omission, substitution or transposition of characters) per word. The individual algorithms are presented in turn and their combination into a unified strategy to correct misspellings is demonstrated. The system was implemented in the programming language Haskell; a pure functional, class-based language, with non-strict semantics and polymorphic type-checking. The use of several features of this language, in particular lazy evaluation, and their corresponding advantages over more traditional languages are described. The dictionaries and spelling correcting facilities are in use in the LOLITA system. Issues pertaining to 'real word' error correction, arising from the system's use in an NLP context, axe also discussed
2
No full textTHE tSITIZEN.
L. P. Hathaway,
Editor and Publisher.
Office In ihe l'jtklnson Building. l*nl
earsiiy Aventte, Palo Alto, California.
USUSD KVKkY SATIHDAY.
Price ot Subscription!
Fifty Cents m Year.
Tclepbooe Main Ati.
Muke-In-1- ablli-llie .UU shlllCS.
Keep up ihr agitation lur gisal Mrteta,
L.-kfiiribi' iinbrn lala-l; then Miim*
llie gfssl*—that la If ymi want lo, and
ttmsl everyone dis-a.
Ihlite Vtitlr hi la lo thf ii-|ebintiu
to I* hi'lil at Palo All,, on tin- Fourth
MI them lln-re'll !«■ dancing In the
after
Tlnai' lit. tiek. I- fur Sunt* I'm-, in.-
how ready-— Imi
lutein liYanil un the light a|t,t. — I ■-
.Angel*.*. Tiines.
* t 1 ^
The a|.jilatise ilmi f..Ht.*»-*l the rea.1
Ing nf the names <d applieaiita at tin
-Maalnli of th.' Alliance In"-In*, evening.
W«. music |.> the rur uf llu. ,|,., i|I. . nf
I na- A i
Tbe agitating pluiuticrB hare all left
(own; tltry Iiavee-me int.. girener |
hn-ea alien- btud-iit<«ilhed ln-eltng
against \emee ami fpamm*l\ may aland
Ibent better in bam', tlain II *l*l t-rre.
li rail.'T-li *kt*l —ti..- ttni-tn paafli
lo learn tliat tbt Cbanda-t .*f O—aaina
*d Han FraiM-i**-.! urg*.l it* utemla-ra lu
loin lite CitlMiia" .-alliance. Thla la
■Silly "ne inatanre where intcrr-Mi are al
wairb In an rflitrt fc. ItlMMl Um mem-
itwr ship uf i)h- gn-ale*l Italy lltat wa*
liver ft.rmcd.
Psln-itin- Pal.. All" liakeries; ami
don't mjhjat that many I hi ml I** ul Isuu-
■Iry u -ti are still .'I..' lo ftsu J'-ae
natwltlMlainlluglm-al laundries aw giving the l-eal ol saiislsi-tlim. tt Is laid
.enough t» iMtniniie nul-ol-lfWii Lnall-
tutlons but It is still worse II tin*.'
Instil uts-oii* li.ij.|.-n tn Is- in the Uliluus.
A vide . Boyd snd J. J. Morris, Ihe
Fourth of July tluauei' euuiiiilllee, lur
the e seel lent w-itrkit.nn> TiM-sday In so-
rutingsultm-rlptiuns fur uaatly eimiigb
money to Insure the suiif-a "I Ihe big
tolebralion tlmt ia Mug arranged for.
Typhttid will ih> longer miniare Die
human family alien the discnery- bii-
twnimrol lliia week hy lbs Agriculiural
Department al Wa.blugtoii ia put Into
effect. Stiliitiitna ..( BOfpgf (I !•• l.tUO,-
WOl plan*! in water al onliuary tem-
rereiurei- Ut three liours will kill every
typlttotd ami elmk-ra -* r rii i .-tilaiiisil
llirtriti ami leave Ihe aster altailutely
71..-.-W1..1-, |m u-eull-er.d the lt-wr.1
id TrUflees i-.t the Pat*. Alto publir
fc-b...*. will la> It. I-l Ibe l.i.i Monday In
Jane, ll U tu lie an im|.-rtsui eUrtiurt
ami the |.r*..ti cbuarn f.*r tin- [dace
OtetuVl tar ooe -. m*w
klhellRie to art. tlet Mm- gnuiml snd
im-giesrive Htiseiiahip aill see thst it
h rapidly lurmil into a park. When
a i-anple baeontW "p«tk hungry" It
thinks nf i i'.. and i|i*-«e**.ti.. Humors sre nasty things al
best ami lbs apptail tbey are pntven or
Hnottn the belter for all wnmnHil,
1Kb rtosnl ol Trustees is Invrallgating
!hi* matter and will itinMhto htm
tlargc* ol a serious nature fc. prefer
Sgail.trt the ..iri--t.il lii.jii'-*!:. ii Whellier
Uroot ibat rrw-mf- f will -I.t.- mah> au
•eatuple ul the atlegetl offending oillrei
rem-Jim to b** seen.
nto effect. Tb-! c-amittee baa followed
luggestiom printed some time ago In
Tbe Clilt-en. and, tba writer il.lnks. ad-
■sadly, Tbc ncomtner^xi..:. tint,
after ttraets bare leen macadamitci,
pipes, mains, etc., tha'.lbs laid ber.eath
gotten or sidewalks i* a good noe aad
If thla method It IoIlo*«d there is no
need of ever opening the streets for improvements or rejoin to underground
sj-stem*. whether of water works, eewer,
ga», electric or telephone. Tlie knowledge lltat pru{y bidding OB) Iaa Ma off.-red. uilli
view tu buying. The result ilemunatralea
very clearly tlmt tie |I0 Mr. Seale spent
wllb Tint fili'.-i. fnr advertising hrntigh
greater dliecl returns than the seven
.1 -ia-nt hy Mr. W.a.ter for ad-
vertialng hi San FraneUrti ami thn>ugh
not llie .late. It !• true, tbtphtleaa
lliat Pal- All- will f-ir nllia ami even
ears raaitlntie fc. nmi-rc Iwnefil l.y rea-
—n -I the ailverttaing tl.me l*y Mr.
iter; to fact, tbe effect of paal advert iting !• never-eniling ami lit.
IV -ai.r kiml waa ol llie !in-l cUss
lltitvnli't Mrttora, W'.aler ami Seale
inlctl su results ami time On-y de
red thnalgh llie little a-l written
The filiifft oltlreaml |irinlol In Tlie
Cillsen's ■ "Inn,it-
SOME TIMELY ARTICLES.
l/ical liusineas u who have fell the
inspiration may Is* saked to .•"lilrilaile
■ti.-. of articli* Ihnt The Cltisen
Im- in i*inI•• iupi*llou. Heir are HMM
idthesubjerts-.
I low it Feels In ban One'. Beat
de in a Single Week;"
Mv Mistake iu Holding to the Bag-
gt.l lalK.- ..f I'ul.mlsm I'tilil It Wu.
Fverlasllngty too Uie;"
The l'-i Cause of I'lii-.tiism; ft*
Takes and Mi-take.."
What the Cilliens' Wli.iii.c hau
IX (i.r I'alo Alt", and ll ra I I'miml
It Out;"
"My hiirpriM'Sltlu-Tiiti. Il.ings havi
Taken I
Wb
Hi.
t
rii*. ot
"I Want to U' an Angel i
ie llesaiin Wily."
The t'iti/en lielieves ibh
srti.'i.-t mold prim twrf totoiaatloa
reading, but ll dmitits il it ran get ally
i-ttelo write them. However, then* an-
liii-iin.a men along rnner-ity avenue
names mentloneil) wholly nmipc
tt-nt. In tlieir imalcs! wsy. It. p> int..
these subjects very deeply and li. bring
out llie true path.** the various l>>|>u •
cuovey. r..iiuiiiiiiii-ali'.n* iiin-t n-'l la
ntlletl or folded; semi no tiuiy-vs
Mamnusrripta not arreptnl will ba pea-
.1 In .... .il.t all-
Henry Acted His Part,
But It Didn't Please He*r
i*aO\v. Henry." aaU tbs brble. "I
nm want you to understand ilia-
* ~ ttactly thai I do oot wish to be
taken for n brMe. I am going lo an
exactly as If I wera au old married
woman. Ho, dearest, do not tliluk me
cold aud unloving If 1 treat you rery
practlcally whan there Is anybody by."
I don't nelleva I can paas Tur an
old married man." said Henry. "1 aw
so fond of you tliat I am li J to
allow It. I am sure lo betray myself."
And I Insist thst you behave Just like
all old married men do. Do ynu hear!"
"Well, darling. I'll try. but I know i
shall uot auccccd."
i Ibe llrst evening of their arrival
at tbelr hotel the bride retired, and llie
groom fell In with a whist party, with
whom bu oat playing canls until 4
' lock hi tbo morning. Ilia wife spent
■ he weary hours In weeping. At lasl
he turned up and met tils grief stricken bride wllb the hilarious qucaUou,
Well, ain't I dolug tbo old married
man like a daisy r
'-.■'- never referred to tbo subject
■u-iiii. and eserybody In future knew
that tbey bad Just beeo msrrled.
l-pR ^TTlECT LMPKOVLsAtaENTS.
The iep>rt id the special eomraitli •> of
lb* hoard* ot tra*lc wltb refen-nc-* fc.
♦mprbring tbe atteeta ol PaVt Alio
fcobwie abotfI right and ii b sinUrely
bb^M lid- IWthl ol Trusters will lose no '
title to paifing the rec^mmeirlait-.ti.,
la-aSij- J.Vttr.
A small boy In a country school
drepped his slate so many times during
school boon tbat tbt teacher finally
aald;
"Johnnie, we cannot stand so much
noise frum yoo. This nooo take your
Mate hows*." Early la tbe sfternoon
tb* teacher again beard Johnnie's slate
go "listar* upon il.e Ooor.
' Johimle." the aald severely, "did 1
oot tell you to take your slate bomer*
■Ye*." replied tbe ted. "I did take It
bet-toe."
*Tbea bow c-M&eo It -bt»r ashed
tbe teacher.
"Why." atM sffssUode) • 1 bt-Mfbt it
|a%*
SIBERIA
(That means about the coldest place that can be found)
REFRIGERATORS
-4-1%
Tin-SIHKKIA is just ns COLD us the nnmu
> itiiliohta-f ami is a (peat t*iivt-r uf ICE. On the hot-
I test diiys butter token from .. iirupcrly iced Siberia
I Imp tin- liiii'tlnt'ss of ii chunk uf granite; ami tlu>
I milk reminds one uf wintertime. Few realize how
groat it* lln- quautity uf refrigerator we offer for a
coni]>aratively small .inin of money. Por instance;
mmm
Small family size for - - 10. A little larger one for - - - 15. A great big ice-box for - - 40.
"We Want Your Business"
J. F. Parkinson Company
Hind For Heading Off
The Inquisitive Boy:
AN liwcnioua fatber of a boy wbo
asks i.ii.-..una baa, after mocb
ex perl rn en ting aud tbe expenditure of a deul of precious tbuugbt, aitc-
ceetled In ti'-entlng a ayateni wbsreOy
lie Is hI'Ic to nm-fi-r tils aod lul.lll
gcotly and wltb cum para tl rely Uttls
effort far hours st a stretcb sad wltb-.
out tbe alls litest embarTasaaeoL
Cor Inotance. tbe boy aaka;
**l"apa. wbo made tbat trre growT**
Tbc Ingenious fatber answers:
"God.-
~Wby did God make It growr
-liecsuse be artabed to Bake lbs
world more beaotlfuL**
■ wbj did be wlsb to make tbe world I
I--..-.- beantlfuir*
"Becaose be saw a pise* wbere a
tree ougbt in stand."
■Wlij did be see a (lac* wbar* a
tree ougbt to stand?"
"Because be wlsbed to make tbe
world more beaotlful.**
"Hut wny did lie wtab lo make lbs
world more boautafoir*
"Because be saw thnt place wbere
s tree ought to stand."
Thus tlie matter become* one of mere
pbyslcal endurance. Tbe system works
as well on one subject as anotber. Let
us sttppose'that tlitr boy asks:
"I-'aiber, wby does ibat man wear a
goatcoT"
"Because," answers tbe fatber, "be
tblnks It Improves bis looks."
"Why does be tbluk It Improrn bis
looter
"Because be Is foolish."
"Wby Is be foolish r
"Bccaustt be tliluks bla goates* lm>
tirorea bis looks."
"*tVhy does be tblnk ft Improves bis
lookaV
"iv-tuni- be is foolisti."
"Well, wby Is be foollsBr
-Ii.-e-.Ti*,. be thinks bU goatee Im
pro res bis looks.'
"I'm coins to nak yon a eatcb question. Miss Wllllug."
"Ob. Ibis la ao sudden. Hr. 11mId r
"But wby does be tbluk It Improreo
bis looker'
"Because be la foolish."
Tbe system may not be at elaborate
as same of tfcotte derised to brtaik tbe
bank at Monte Carlo, but It Is faf more
prodnrtlve of Kratlfylo*- results. Wltb
a llllle pmetlce any Weary fatber ran1
efwrate It succeufolly. aod we shall!
be dltappotnted If It Is not speedily
neoeniird as ooe of tbe Inestimable
boons conferred upon nfeokind.—CM
case sUewrd-ntfald.
• "■. i..- *-■■ ■ ■ I ■ -1 j ii * i
tbe family bis ciicageuivnl.
Mcniimer—What, that girl! Wby. she
aqulnU.
Hlsler-Sbe bas absolutely no stylo.
Auntie— Itedbeaded. ain't sbcT
Orandma—I'm nfeere.1 alie'a dlgbty.
I'ficle—Stic hasn't any money.
First Cousin J'ru-Suo doesn't look
strong-
fteeond Cousin Jane-lthe's stuck up.
Third Cousin Jrtcbcl-She's an o«-
tracagtflt tblnc.
Tbe fnti (lhoticI>lfully)-WelI, abe'a
got one retleemttii: feature anybuw.
Chorus-Win fs that!
T|te Hon—She hasn't a relative OD
eaflb.
I-opper-Grab her, my boy; grab ber.
- riir-i■!■:,: Peat.
aa ct.ttf,
Tommy -What's an "eueore*" tMtoUel
Attaile- An "enrore" I* * lien yon sre
asked to so oeet tbe saBke thing ogals.
Tommy -Then ay teacher ts al-ray»
a at
Jbast * Heal Itttairtiral.
Kitty-Nell makes a big display of
tbat encasement ring of hers, ily
brother Kred says It Isn't a real dla-
lieasle lutt then, yotf know, ber eu
gagement ls*i't a real ottw either. SM
• M I'rauk nfv engtiKt-d only In a sort
«f way, yo* %t>..u -Hvet-ti TtJus^rH't'
rt*i—4\pya
.J5
Order at once!
Summer Suits, Cut and Made to
Order, from Any Summer Goods
in the House for
Only Fifteen Dollars
Made to. Order
a Fit Guaranteed
Three Little tailors
t^BtWM,HHaitagt*—
Phone Black II!. 259 University Ave.
15--
^AmjApsamap\pAwA*pm^
rateke.
-But wby did tb* Ut.its fguremlM
as a woauor*
"WeiL ^u know, tbe fairer (ne
mind th*. longer II la la being tarn*/
Hathaway
ihe painter
Is ready to have a chat with you
about that painting you have been
putting oft so long'.
Gall up 'phone uBIue 2141
