24,853 research outputs found
Temperature and humidity profile retrievals from ground-based microwave radiometers during TUC
Thermodynamic atmospheric profiles have been retrieved from ground-based microwave radiometers during the Temperature, hUmidity, and Cloud (TUC) profiling campaign. A variety of inversion methods is presented, in terms of requirements, advantages, and limitations. Results confirm the theoretical expectation that retrievals’ accuracy and resolution degrade steadily with height up to 3 km, then more rapidly. At higher levels the retrievals’ accuracy does not improve on that of a Numerical Weather Prediction model, which provides a background for the variational technique. Most retrieval methods produce a bias in the temperature profile above 1 km, which may be due to a bias in the absorption model used and/or observations at 51–54 GHz. Elevation scanning is shown to improve the accuracy and resolution of the retrievals in the boundary layer, but is limited by technical shortcomings
Choreographic Morphologies: digital visualisation of spatio-temporal structure in dance and the implications for performance and documentation
Ersatz Dance and the e-dance project: James Hewison was a research collaborator, creative artist and performer in the e-dance project (funded by JISC, AHRC £400,000.00) from 2008 to 2010. Professor Helen Bailey (University of Bedfordshire) was the Principal Investigator with co-investigators from University of Manchester and The Open University. The project’s artistic and practice-based output was realised through the work of Ersatz Dance Company (Dir. Bailey), for which Hewison was an Associate Director, creative-collaborator and performer. The following research paper was an output from the e-dance project: Bailey, H., Hewison, J., Turner. M. (2008) “Choreographic Morphologies: digital visualisation of spatio-temporal structure in dance and the implications for performance and documentation” in EVA2008 International Conference Proceedings, British Computing Society, UK ISBN 978-1-906124-07-6
Modelling the influence of vitamin D and probiotics on inflammation and the intestinal microbiota in older adults
The relationship between the intestinal microbiota and human health during ageing is an area of increasing interest due to increasing health challenges experienced by ageing populations. This paper develops a mathematical model describing the age-related biological changes associated with alterations to the microbiota, vitamin D levels, immunosenescence and inflammageing to determine the likely impact of manipulating the intestinal microbiota with dietary components. Age-dependent parameters are incorporated into a previously developed model to determine the evolution of intestinal bacterial populations, vitamin D receptor:1,25 dihydroxyvitamin D levels, epithelial barrier integrity and immune response with increasing age. Results suggest an age-related decline in both innate and adaptive immunity, weakening of the intestinal barrier, elevation in systemic inflammation and reduced serum vitamin D, resulting in individuals over 60 years old becoming vitamin D deficient (<50 nmol/L). Numerical simulations indicate that administration of probiotics and/or vitamin D supplements upregulates the VDR complex at all ages, which helps restore epithelial barrier function, particularly in older adults in whom the intestinal barrier has been compromised. The greatest benefit is derived from co-supplementation with probiotics and age-dependent doses of vitamin D. Finally, the value of gathering additional experimental data motivated by the modelling insights is discussed
Jack Alive / Martin Dead : The Location of the "Author" in Jack London\u27s Martin Eden
This essay is an attempt to read Martin Eden, Jack Londonʼs autobiographical novel, in terms of the inextricable relationship between the author and the protagonist. Critics have often taken the unbalanced plot and the lack of ironic distance between narrator and character in Martin Eden as the technical weakness of London, but this paper argues that the achievement of this novel owes a great deal to the attachment of London to Martin. The unbalanced structure is a necessary product of the severe struggle of the author to kill his romantic alter ego. // Martin, who aspires to win Ruth Morse, tries to cross class boundaries by making a career of a writer. Even after realizing the emptiness of Ruth, who turns out to be nothing but a typical figure of the bourgeoisie, he somehow persists in loving her. The notion underlying here is that, for Martin, love, career and art are fundamentally inseparable. He objects to the aestheteʼs view of Brissenden on account of his separation of art from career. Martinʼs identity and life consist only in the triunity of love/career/art; the alternative is the repudiation of life. Thus, the unnatural delay of his disappointment in love can be regarded as Londonʼs strategy to set the suicide of Martin as the necessary consequence of the story. // By finishing the story and killing Martin, London finally detaches himself from Martin, reconstructs his self, and, unlike Martin, survives as a professional writer. In this sense, Martin Eden is a story about “writerʼs self-reconstruction.
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Letter from Martin Chizzick
Congratulations to Duane Pearsall for receiving the Enterpreneur of the Year award; note on the letter was written by Pearsall and it mentions that Martin, the author of the letter, died in a airplane accident
Robert Martin Tiffin's Mystery Man Newspaper Articles
Advertiser-Tribune newspaper clippings featuring a story about Robert Martin (written by Nancy Kleinhenz), a local author from Tiffin (Ohio) who wrote under the pseudonym of Lee Roberts, and two of his short stories. Martin wrote mystery novels in his spare time, creating more than 22 mystery novels. For more information about Robert Martin and a list of books go to http://www.mysteryfile.com/RMartin/JBennett.html
Vitamin D and rheumatoid arthritis
1,25-dihydroxyvitamin D (1,25(OH)2D) has potent immunomodulatory properties, and many immune cells express the vitamin D receptor (VDR) and the 1α-hydroxylase (1α-OHase) enzyme that synthesizes 1,25(OH)2D from precursor 25-hydroxyvitamin D (25(OH)D). Thus, the immune system is intimately linked to the vitamin D system, and insufficiency of vitamin D may impair both innate and adaptive immune function. Low serum levels of 25(OH)D have been associated with increased risk and severity of autoimmune diseases. This chapter focuses specifically on the relationship between vitamin D and the autoimmune disease rheumatoid arthritis (RA). In addition to describing the mechanisms that link 25(OH)D and 1,25(OH)2D with inflammatory immune responses, this chapter will also document the wide array of studies that have shown association between serum 25(OH)D and RA disease, and the vitamin D supplementation studies that have explored possible beneficial effects of vitamin D supplementation of RA.</p
Experiences Using Large Scale Video Walls for Distance Education
We describe our experiences building and using the Rutgers Videowall, a low-cost telepresence system that has been used teaching 15 courses and colloquia. By relaxing typical spatial telepresence features, such as background continuity, we greatly reduced costs and gained flexibility in the rooms it could be deployed in. The lower costs and room flexibility enabled academic departments to use the wall, in contrast to traditional telepresence systems which remained inaccessible. We found that the Videowall’s spatial distortions did not have a significant impact on useability, as our initial survey results show that students had an overall positive experience.Technical report DCS-tr-72
Response to Dr Zittermann
This article relates to - Functional effect of physical exercise on calcium metabolismArmin ZittermannVolume 603Issue 5The Journal of Physiology pages: 1323-1323 First Published online: January 2, 2025The effect of an acute bout of exercise on circulating vitamin D metabolite concentrations: a randomised crossover study in healthy adultsSophie E. Davies, Oliver J. Perkin, James A. Betts, Javier T. Gonzalez, Martin Hewison, Carl Jenkinson, Kerry S. Jones, Sarah R. Meadows, Damon A. Parkington, Albert Koulman, Dylan ThompsonVolume 602Issue 17The Journal of Physiology pages: 4157-4170 First Published online: August 4, 202
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