1,721,038 research outputs found
Seven year follow-up imaging study comparing conventional radiography and ultrasound in rheumatoid arthritis finger joints
No full textComparison of the efficacy of contrast-enhanced ultrasonography and magnetic resonance imaging in detecting synovial process in patients with knee osteoarthritis compared to healthy subjects.
No full textSignificance of B-mode, power Doppler- and echo-intensifier sonography in RA patients under anti-TNF alpha treatment
No full textIs a double dose of contrast material needed in dedicated, low field MRI for assessing synovitis?
No full textComparison of the efficacy of contrast-enhanced ultrasonography and magnetic resonance imaging in detecting synovial process in patients with knee osteoarthritis compared to healthy subjects.
No full textSignificance of B-mode, power Doppler- and echo-intensifier sonography in RA patients under anti-TNF alpha treatment
No full textDas typische röntgenologische Bild der rheumatoiden Arthritis in Hand- und Vorfußaufnahmen : Analyse einer Patientenkohorte an einem Schwerpunktzentrum
Full text linkIm klinischen Alltag wird die Diagnose einer rheumatoiden Arthritis (RA) vorrangig anhand von Symptomatik und Laborchemie gestellt. Das konventionelle Röntgen kommt additiv zum Einsatz. Eine RA-Klassifizierung ist gemäß ACR-EULAR-Klassifikationskriterien von 2010 anhand des Röntgenbildes möglich. Die EULAR-Taskforce veröffentlichte 2013 eine Definition des typischen Musters. Ziel der Studie ist die Erarbeitung eines neuen Kriteriensets zur röntgenologischen Klassifikation der RA. Es wird die Frage geklärt, ob und zu welchem Prozentsatz diese Kriterien von Patienten mit diagnostizierter RA erfüllt werden. Es wurden die Röntgenbilder der Hände und Vorfüße von 230 Patienten eines Schwerpunktzentrums untersucht. 23% der Patienten hatten ein typisches RA-Röntgenbild nach unserer Definition. Die Mehrheit der Patienten war seropositiv. Typische Erosionen lagen oft bereits zur Erstdiagnose vor. Unser Kriterienset besitzt eine höhere Sensitivität (25%) als die EULAR-Definition von 2013 (16%).In everyday clinical practice, the diagnosis of rheumatoid arthritis (RA) is primarily made on the basis of symptoms and laboratory chemistry. Conventional X-rays are also used. RA classification is possible according to the ACR-EULAR classification criteria from 2010 based on the X-ray image. The EULAR task force published a definition of the typical pattern in 2013. The aim of this study is to develop a new set of criteria for the radiographic classification of RA. The question of whether and to what percentage these criteria are met by patients diagnosed with RA will be clarified. The radiographs of the hands and forefoot of 230 patients at a specialist center were examined. 23% of the patients had a typical RA radiograph according to our definition. The majority of patients were seropositive. Typical erosions were often already present at initial diagnosis. Our criteria set has a higher sensitivity (25%) than the EULAR definition from 2013 (16%)
Prospective 7 year follow up imaging study comparing radiography, ultrasonography, and magnetic resonance imaging in rheumatoid arthritis finger joints
No full textObjective: To perform a prospective long term follow up study comparing conventional radiography (CR), ultrasonography ( US), and magnetic resonance imaging (MRI) in the detection of bone erosions and synovitis in rheumatoid arthritis ( RA) finger joints. Methods: The metacarpophalangeal and proximal interphalangeal joints II - V ( 128 joints) of the clinically dominant hand of 16 patients with RA were included. Follow up joint by joint comparisons for erosions and synovitis were made. Results: At baseline, CR detected erosions in 5/128 (4%) of all joints, US in 12/128 (9%), and MRI in 34/ 128 (27%). Seven years later, an increase of joints with erosions was found with CR (26%), US (49%) ( p< 0.001 each), and MRI (32%, NS). In contrast, joint swelling and tenderness assessed by clinical examination were decreased at follow up ( p = 0.2, p< 0.001). A significant reduction in synovitis with US and MRI ( p< 0.001 each) was seen. In CR, 12 patients did not have any erosions at baseline, while in 10/ 12 patients erosions were detected in 25/96 ( 26%) joints after 7 years. US initially detected erosions in 9 joints, of which two of these joints with erosions were seen by CR at follow up. MRI initially found 34 erosions, of which 14 (41%) were then detected by CR. Conclusion: After 7 years, an increase of bone erosions was detected by all imaging modalities. In contrast, clinical improvement and regression of synovitis were seen only with US and MRI. More than one third of erosions previously detected by MRI were seen by CR 7 years later
Diagnostic quality and scoring of synovitis, tenosynovitis and erosions in low-field MRI of patients with rheumatoid arthritis: a comparison with conventional MRI
No full textObjective: To compare dedicated low- field MRI ( lfMRI) with conventional MRI ( cMRI) in the detection and scoring of synovitis, tenosynovitis and erosions in patients with rheumatoid arthritis. Patients and methods: The wrist and finger joints of 17 patients with rheumatoid arthritis ( median ( range) disease duration 8 years ( 7 - 12); Disease Activity Score 3.3 ( 2.6 - 4.5)) were examined by 0.2 T lfMRI and 1.5 TcMRI. The protocols comprised coronal spin- echo and three- dimensional gradient- echo sequences before and after contrast medium administration. Synovitis of the metacarpophalangeal and proximal interphalangeal joints 2 - 5 and the wrist joints was scored according to Outcome Measures in Rheumatology recommendations. Tenosynovitis and erosions were scored using 4- point and 6- point scales, respectively. The results were analysed by calculating k values and performing McNemar's test intra- individually on a joint- byjoint basis. Results: Agreement between the two MRI techniques was good to excellent for synovitis and erosions, and moderate for tenosynovitis. Of the 306 joints evaluated, 245 and 200 joints showed synovitis in lfMRI and cMRI, respectively. Scoring of synovitis of the finger joints yielded k values from 0.69 to 0.94. Of the 68 flexor tendons evaluated, tenosynovitis was diagnosed by lfMRI in 24 and by cMRI in 33 instances. Of the 391 bones evaluated, 154 and 139 showed erosions in lfMRI and cMRI, respectively. k values for erosion scores were between 0.65 and 1. Conclusion: Dedicated, lfMRI shows high agreement with cMRI in diagnosing and scoring synovitis, tenosynovitis and erosions in rheumatoid arthritis when using standardised scoring systems
Comparison of sagittal laser optical tomography with ultrasound and clinical examination for diagnosis of synovitis in proximal interphalangeal joints
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