164 research outputs found
Complexity and the Law of Armed Conflict
No full textCo-Discussants: Prof. Bill Banks, Syracuse Law School and Ms. Rita Siemion, International Legal Counsel, Human Rights First
Author: Brig. Gen. Ken Watkin, former Judge Advocate General, Canadian Forces, author Fighting at the Legal Boundaries: Controlling the Use of Force in Contemporary Conflict
Author: Prof. Jeremy Rabkin, George Mason Law, author (with John Yoo), Striking Power: How Cyber, Robots, and Space Weapons Change the Rules for Wa
Fighting at the legal boundaries ::controlling the use of force in contemporary conflict /
No full text'Fighting at the Legal Boundaries' offers a holistic approach towards the application of the various constitutive parts of international law. The author focuses on the interaction between the applicable bodies of law by exploring whether their boundaries are improperly drawn, or are being interpreted in too rigid a fashion. Emphasis is placed on the disconnect that can occur between theory and practice regarding how these legal regimes are applied and interact with one another
The Invisible Opportunity: All the Light We Cannot See (in Research)
No full text This article articulates the growth that occurs in graduate school when the author comes to terms with their disability as being a positive contribution to their scholarly work by using it in practice-based and embodied research. It explores a project which illuminated the possibilities of embodied research by renegotiating the emphasis of visual performance on stage and by claiming space in graduate life to work with disability to bring new perspectives to scholarly work. </jats:p
Roman Cheshire; or, A description of Roman remains in the county of Chester [archival photocopy] /
No full textPhotocopy.Mode of access: Internet.Photocopied
Review of Book: This Transcending God, the Teaching of the Author of ‘the Cloud of Unknowing’
No full textGrethe Kjaer: 'Thomasine Gyllembourg, Author of a Story of Everyday Life'
No full textNo description availabl
Misuse of Uniforms, Emblems, Flags, Insignia, and the Ukraine Conflict
No full textMisuse of Uniforms, Emblems, Flags, Insignia, and the Ukraine Conflict examines how the 2022 invasion of Ukraine has renewed the relevance of international humanitarian law governing the misuse of uniforms, emblems, flags, and insignia in modern inter-state warfare. It documents allegations that parties have worn enemy or neutral uniforms, used protected insignia such as Red Cross markings, or engaged in other deceptive measures that may constitute treachery or perfidy. The author analyzes the legal definitions and prohibitions under the law of armed conflict regarding improper use of distinctive signs for deception, distinguishing between lawful ruses and forbidden perfidious conduct. The work also addresses the challenges of accountability when both sides may engage in similar deceptive practices, raising potential tu quoque issues. Ultimately, Misuse of Uniforms, Emblems, Flags, Insignia, and the Ukraine Conflict highlights how such reciprocal deception complicates the successful prosecution and enforcement of international norms in the Ukraine conflict
Interaction of UVA (320-380 nm) radiation with human skin cells
No full textThe generation of reactive oxygen species (ROS) by UVA radiation (320-380 nm) is responsible for damage to intracellular biological macromolecules, cytotoxicity and many other effects. Both the endogenous chromophore protoporphyrin IX (PPIX) and 'free' iron are potentially important sources of ROS after UVA irradiation in human cells. The aim of this study was to determine the importance of PPIX in the inactivation of human cells after UVA irradiation, and to determine what effect UVA irradiation had on intracellular 'free' iron levels. By modulating levels of the intracellular chromophore PPIX in human cells by exogenous administration of the haem precursor #delta#-aminolevulinic acid (ALA) and irradiating these cells with graded doses of UVA, it was determined that the basal content of PPIX in TK6 human lymphoblastoid cells is insufficient to make a significant contribution to the UVA-mediated inactivation of these cells. The basal content of PPIX was however found to make a significant contribution to LTVA-mediated inactivation of the primary human fibroblast cell line, FEK4, which implicates PPIX as a critical UVA chromophore in this cell line. We document in this study the development of a flow cytometry-based fluorescence assay system that is capable of determining membrane damage and changes in intracellular 'free' iron levels. By using this assay and the cytoplasmic aconitase assay, we have confirmed that UVA irradiation of human skin cells results in an increase in intracellular 'free' iron levels. We also demonstrate that while administration of ALA to FEK4 cells does lower the intracellular 'free' iron levels, this type of treatment strongly exacerbates the increase in 'free' iron levels observed after UVA irradiation. The effects of ALA treatment and UVA irradiation on ferritin levels in FEK4 cells was also determined in this study using a polyclonal (anti-ferritin) antibody enzyme-linked immunosorbent assay. We demonstrate in this study that UVA irradiation of cells, and to a much greater extent, UVA irradiation of cells treated with ALA, results in the degradation of ferritin. This provides strong evidence for ferritin being a major source of the increase in intracellular 'free' iron levels observed after such treatments. It is hoped that data obtained from this study will contribute to an advancement in the understanding of the intracellular effects of UVA irradiation and that this may help in the protection against, and prevention of, processes such as UVA-induced photocarcinogenesis and photoageing. (author)Available from British Library Document Supply Centre-DSC:DXN032872 / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo
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