1,966 research outputs found

    Oral History Interview: Helen Parsons (0080)

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    In her three March 1972 interviews with Steven Lowe, Helen Parsons describes her career as a scientist at the University of Wisconsin-Madison and elsewhere from the early 1900s to the 1970s. She discusses her burgeoning interest in science and home economics and how she wanted to bridge the gap between the two disciplines with her research in the biochemistry of nutrition. She offers observations about a number of significant figures in the early history of the School of Agriculture, details her major contributions to nutrition science, and traces the development of a separate School of Home Economics (now School of Human Ecology). This interview was conducted for inclusion in the University of Wisconsin-Madison Archives Oral History Project

    Helen\u27s Choice

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    Quilt pattern from the Linda Lowe Quilt Patterns Collection titled Helen\u27s Choice.https://scholarworks.moreheadstate.edu/lowe_quilt_patterns/1379/thumbnail.jp

    Helen Lowe, stage actress

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    Helen Lowe, stage actressTo order a reproduction, inquire about permissions, or for information about prices see: http://www.lib.washington.edu/specialcollections/services/reproduction/reproduction Please cite the Order NumberScanned at 600ppi with an Epson 20000 flatbed scanner. Image then rotated, cropped, level-adjusted, and sharpened using Photoshop CS3. Converted to a JPEG2000 image upon ingest into CONTENTdm

    Helen Lowe, silent films

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    Helen Lowe, silent filmsTo order a reproduction, inquire about permissions, or for information about prices see: http://www.lib.washington.edu/specialcollections/services/reproduction/reproduction Please cite the Order NumberScanned at 600ppi with an Epson 20000 flatbed scanner. Image then rotated, cropped, level-adjusted, and sharpened using Photoshop CS3. Converted to a JPEG2000 image upon ingest into CONTENTdm

    Sichuan (China), lakes on the saddle below mountains

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    Lakes on the Hai-Tze-Shan saddle below Djara Peak.Image is part of research condcuted by J. Hanson-Lowe for the article: Notes on the Pleistocene Glaciation of the South Chinese-Tibetan Borderland Author(s): J. Hanson-Lowe Source: Geographical Review, Vol. 37, No. 1 (Jan., 1947), pp. 70-87 Published by: American Geographical Society Stable URL: http://www.jstor.org/stable/211362http://www.jstor.org/stable/211362Grayscal

    Sichuan (China), hanging valleys formed by glaciers

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    Hanging valley on left-hand wall of valley below, and to east of the Sara La.Image is part of research condcuted by J. Hanson-Lowe for the article: Notes on the Pleistocene Glaciation of the South Chinese-Tibetan Borderland Author(s): J. Hanson-Lowe Source: Geographical Review, Vol. 37, No. 1 (Jan., 1947), pp. 70-87 Published by: American Geographical Society Stable URL: http://www.jstor.org/stable/211362http://www.jstor.org/stable/211362Grayscal

    Impaired neural development in a zebrafish model for lowe syndrome

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    Lowe syndrome, which is characterized by defects in the central nervous system, eyes and kidneys, is caused by mutation of the phosphoinositide 5-phosphatase OCRL1. The mechanisms by which loss of OCRL1 leads to the phenotypic manifestations of Lowe syndrome are currently unclear, in part, owing to the lack of an animal model that recapitulates the disease phenotype. Here, we describe a zebrafish model for Lowe syndrome using stable and transient suppression of OCRL1 expression. Deficiency of OCRL1, which is enriched in the brain, leads to neurological defects similar to those reported in Lowe syndrome patients, namely increased susceptibility to heat-induced seizures and cystic brain lesions. In OCRL1-deficient embryos, Akt signalling is reduced and there is both increased apoptosis and reduced proliferation, most strikingly in the neural tissue. Rescue experiments indicate that catalytic activity and binding to the vesicle coat protein clathrin are essential for OCRL1 function in these processes. Our results indicate a novel role for OCRL1 in neural development, and support a model whereby dysregulation of phosphoinositide metabolism and clathrin-mediated membrane traffic leads to the neurological symptoms of Lowe syndrome. © The Author 2011. Published by Oxford University Press. All rights reserved

    Sichuan (China), view of mountains across from Litang plain

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    Looking across the Litang plain from somewhat east of that town. The "Lama's Hat" peak lies in the center of the picture and is flanked by corries.Image is part of research conducted by J. Hanson-Lowe for the article: Notes on the Pleistocene Glaciation of the South Chinese-Tibetan Borderland Author(s): J. Hanson-Lowe Source: Geographical Review, Vol. 37, No. 1 (Jan., 1947), pp. 70-87 Published by: American Geographical Society Stable URL: http://www.jstor.org/stable/211362http://www.jstor.org/stable/211362Grayscal

    Supplemental Material - Depression literacy in older Chinese people in New Zealand

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    Supplemental Material for Depression literacy in older Chinese people in New Zealand by Helen Lowe and Gary Cheung in Australasian Psychiatry</p
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