17 research outputs found

    Pregnancy and insulin sensitivity in relation to Exercise training (A scoping review)

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    Abstract: This study is aimed to estimate the relation of exercise training on insulin sensitivity and pregnancy. Twenty females at the second trimester of pregnancy participated in this study. Their age was 20 to 40 years with BMI less than 35 km2. They divided into two equal group. The study group (A) performed exercise program for four weeks, 3 sessions per week. While the control group maintain their daily life activity routine. There was a significance difference in the mean value of insulin sensitivity level in group A and there was a significance difference in the mean value between groups in favoring to group (A). So, it could be concluded that exercise training is an effective method on insulin sensitivity during pregnancy. Keywords: pregnancy, insulin senstivity, exercise training. Title: Pregnancy and insulin sensitivity in relation to Exercise training (A scoping review) Author: Heba Embaby, Mohamed Elbanna International Journal of Novel Research in Healthcare and Nursing ISSN 2394-7330 Vol. 9, Issue 3, September 2022 - December 2022 Page No: 192-198 Novelty Journals Website: www.noveltyjournals.com Published Date: 10-November-2022 DOI: https://doi.org/10.5281/zenodo.7310301 Paper Download Link (Source) https://www.noveltyjournals.com/upload/paper/Pregnancy%20and%20insulin%20sensitivity-10112022-1.pdfInternational Journal of Novel Research in Healthcare and Nursing, ISSN 2394-7330, Novelty Journals, Website: www.noveltyjournals.co

    Insulin sensitivity and plasma glucose response to aerobic exercise in pregnant women at risk for gestational diabetes mellitus

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    Background: Gestational diabetes mellitus (GDM) is one of the common complications that occur during pregnancy. Early intervention is essential to prevent the development of the disease in the non-pregnant state but also helpful in preventing the occurrence of GDM. The aim of the study was to assess the effect of aerobic exercises on insulin sensitivity and fasting plasma glucose level in pregnant women with risk for gestational diabetes mellitus.Materials and methods: Forty multigravidae women between 20-24 weeks of gestation with risk for GDM were randomly selected (age range was 25-35 years), body mass index ranged from 30-35 kg/m². Women were divided into two equal groups: intervention group (A), which followed an aerobic exercise program in the form of walking on treadmill, three times weekly until the end of 37 weeks of gestation in addition to diet control. Control group (B) which received diet control with usual care given by obstetricians and midwives. Evaluation of the women in both groups was carried out before and after treatment program through assessment of fasting blood glucose and insulin levels.Results: There was a highly statistically significance decrease in fasting blood glucose level, fasting insulin level in both groups where the p value was 0.0001 favoring group (A).Conclusion: Moderate intensity of aerobic exercises were effective in reducing fasting blood glucose level and fasting insulin level in pregnant women with risk for gestational diabetes mellitus.Keywords: Aerobic exercise, Blood glucose level, Insulin level, Pregnancy, Maternal diabete

    EFFECT OF STABILIZING EXERCISES AND ACUPUNCTURE ON POSTPARTUM SACROILIAC PAIN IN EGYPTIAN FEMALES: A RANDOMIZED CONTROL TRIAL

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    Background: Postpartum sacroiliac joint pain, is a serious problem for the mother, affect the ability to perform daily activities and minimize health-related quality of life. This study aimed to determine the effect of stabilizing exercises and acupuncture on postpartum sacroiliac pain. Methods: Forty multiparous women with sacroiliac joint pain (SIJP), were included, aged 25 to 35 years, BMI not exceed 30kg/m², parity less than 3 times, and delivered normally, they're assigned into two equal groups. Group (A) performed stabilizing exercises for lumbo-pelvic muscles and acupuncture. Group (B) received only acupuncture, were performed three times per week for two months (24sessions). The assessment throughout the present pain intensity (PPi) and the Oswestery disability questionnaire before and after the treatment. Results: It revealed a significant decrease in the PPi scores and a significant improvement in functional disability in both groups (A,B). Group (A) showed a significant decrease in the PPi scores and significant improvement in functional disability with percentage of improvement was 75%% & 62.5% respectively more than in the group (B) the percentage of improvement was 40% & 46.7% respectively. Conclusion: These results indicate that the lumbo- pelvic stabilizing exercises in conjunction with acupuncture were effective adjunct methods in alleviating postpartum sacroiliac joint pain

    Virtual reality-assisted learning: enhancing psychomotor competence in midwifery nursing students

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    Abstract Introduction The integration of virtual reality (VR) in nursing and midwifery teaching has emerged as a promising global trend. Educators have adopted VR to enhance students’ education and ensure safe clinical practice. Aim To evaluate the impact of virtual reality-assisted learning on enhancing psychomotor competence among midwifery nursing students. Methods A quasi-experimental study was conducted at the Faculty of Nursing, Suez Canal University, specifically in the simulation clinical laboratory and the antenatal outpatient clinic of the university hospital. Stratified random sample of 60 midwifery undergraduate nursing students were divided equally into study and control groups. Data collection occurred between September 2024 and January 2025 using five tools: a self-administered questionnaire, the System Usability Scale, Leopold’s maneuver checklist, an antenatal maternal physical assessment tool, and a student satisfaction questionnaire. Results VR-assisted training led to higher post-test knowledge scores compared to traditional methods, though the difference was not statistically significant (p = 0.35). There was no statistically significant difference between the study and control groups in psychomotor competence for both Leopold’s maneuver and maternal assessment prior to the intervention (p = 0.11 and p = 0.07, respectively). However, following the VR intervention, the study group demonstrated significantly higher psychomotor competence in Leopold’s maneuver (43.13 ± 1.46; 42.6 ± 3.82) and maternal physical assessment (36.33 ± 1.81; 37.6 ± 0.67) compared to the control group (36.53 ± 2.29; 32.77 ± 4.28) and (30.13 ± 3.98; 27.3 ± 3.96) in immediate and follow-up posttests respectively (p = 0.000). Additionally, 97% of the study group achieved Grade A (superior psychomotor performance) based on system usability with VR, and 63.3% reported being extremely satisfied with the VR learning experience. Conclusion The study concluded that midwifery nursing students who received virtual reality-assisted training demonstrated better psychomotor competence, superior performance, and greater satisfaction compared to those trained using traditional simulation methods. However, although the VR group showed higher knowledge scores, the difference was not statistically significant. Recommendation It is recommended to incorporate VR-assisted learning into midwifery and maternal health education to enhance students’ psychomotor skills. Ongoing collection of student feedback is essential for continuous improvement of the VR learning experience

    Effect Of Low-Intensity Laser Acupuncture And Reflexology In Relieving Dysmenorrhea: A Randomized Control Trial

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    Background: Dysmenorrhea is defined as painful contractions which arise directly earlier/throughout menstruation time. Dysmenorrhea could be primary or secondary. These cramps are considered the most familiar complaints seen in 50% of women in their fertility time. Owing to the negative influence of medications and their 20-25% failure percentage, many women search for new adjunctive therapeutic approaches. Objective: The present study attempts to detect the influence of low-intensity laser acupuncture therapy (LILT) and foot reflexology in treating primary dysmenorrhea (PD) in female students. Methods: 50 females with PD participated in this trial; their ages ranged from 19-28 years; they were allocated randomly into two groups; intervention and controls. The intervention group received laser acupuncture and foot reflexology for 24 sessions 3 times per week for (2 consecutive menstrual cycles), and the control group received Ibuprofen (400 mg), 1/8h for 3 days during cycles. Results: There was a significant improvement in pain level and functional ability after treatment in each group in favor of the intervention group. Conclusion: laser acupuncture combined with foot reflexology effectively reduces pain and improves functional ability in treating PD

    Impact of foot reflexology combined with dietary modification on premenstrual syndrome: A randomized controlled trial

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    Purpose: This investigation was intended to know the impact of reflexology of the foot on premenstrual syndrome management. Methods: Fifty single female subjects diagnosed with premenstrual syndrome (PMS), aged 18 to 25 years old and BMI ≤ 30kg/m2, participated in this study. They were divided into two groups of equal numbers, A and B. Group (A) got the therapeutic reflexology of the foot in addition to the dietary modification, 3 sessions weekly for eight weeks. The group (B) got only the diet modification for eight weeks. All subjects in the two groups were assessed for pain by the visual analogue scale (VAS), and the PMS related symptoms were assessed by the Premenstrual Daily Symptoms Questionnaire, in addition to the beta-endorphin level in the blood. Results: The results showed significant improvement of pain level, beta-endorphin level in blood and premenstrual related symptoms in both groups when comparing pre and post treatment values (p < 0.05). There was significant difference between both groups post treatment in favor of the study group (A) (p < 0.05). Conclusion: Reflexology of the foot in addition to dietary modification is an efficacious technique for decreasing the premenstrual symptoms

    Photobiomodulation and trigger band technique on groin adductor strain in athletes: Single-blinded randomized control trial

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    Aim of the study: In athletes, groin pain-related adductor strain is a common problem in sports medicine, like groin injuries, so the study investigated the effect of Photobiomodulation (905 nm) and Trigger Band Technique (TBT) on handball athletes' groin adductor strain. Methods: Forty handball athletes with adductor groin strain were divided into an experimental group (A) that received Diode laser 905nm, TBT, and medical treatment, while control group (B) received sham laser with TBT and medical treatment for four weeks. Outcome measures investigated Copenhangen hip and groin outcome score, pressure algometry, creatine kinase, and lactate dehydrogenase levels. Results: Both groups showed a significant improvement in the post-treatment outcome measures, where experimental group showed more significant improvement than the control group with p-value >0.05. Conclusion: results imply that treatment of handball athlete's groin adductor strain by TBT and low-level laser is more effective than TBT alone

    Evaluation of the Prognostic Role of Leptin and Cyclin D1 Expression in Colorectal Cancer

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    Background: Colorectal cancer (CRC) is one of the most malignancies worldwide. This study aimed to determine the role of leptin and cyclin D1 in CRC and their association with clinicopathological parameters and clinical outcomes of patients, and to compare them with normal tissues.Method: A retrospective study was carried out on 60 specimens classified as 8 normal colonic mucosae, 40 patients suspected to have CRC, and 12 colonic dysplasia (CD) and were evaluated in terms of tumor node metastases staging using multislice computerized tomography scan, quantitative real-time polymerase chain reaction to calculate relative leptin mRNA expression level; and immunohistochemical staining was performed to study leptin and cyclin D1 expressions in CRC and CD versus the normal colonic mucosa. Normal mucosa was obtained by colonoscopy from patients for causes other than neoplasia or dysplasia. Statistical analysis was performed using the Statistical Package for the Social Sciences (SPSS 24 Inc. Chicago, IL, USA) with a significance value of P ≤ 0.05.Results: There was a significant association between leptin and cyclin D1 positive expressions and both CRC and CD. However, poor clinical outcome was significantly correlated with high positive leptin and cyclin D1 expressions detected in CRC patients. Cyclin D1 and leptin showed a strong association with greater histological grade, stage, positive LN, and distant metastases of CRC.Conclusion: Expressions of leptin and cyclin D1 are associated with colon disorders with unfavorable outcomes in colon cancer. New opportunities may emerge from the discovery of cross-talk between leptin and other oncogenic pathways in obesity-related cancers, with a particular focus on colon cancer

    Diacerein provokes apoptosis, improves redox balance, and downregulates PCNA and TNF-α in a rat model of testosterone-induced benign prostatic hyperplasia: A new non-invasive approach.

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    One of the most prevalent chronic conditions affecting older men is benign prostatic hyperplasia (BPH), causing severe annoyance and embarrassment to patients. The pathogenesis of BPH has been connected to epithelial proliferation, inflammation, deranged redox balance, and apoptosis. Diacerein (DIA), the anthraquinone derivative, is a non-steroidal anti-inflammatory drug. This study intended to investigate the ameliorative effect of DIA on the prostatic histology in testosterone-induced BPH in rats. BPH was experimentally induced by daily subcutaneous injection of testosterone propionate for four weeks. The treated group received DIA daily for a further two weeks after induction of BPH. Rats' body and prostate weights, serum-free testosterone, dihydrotestosterone, and PSA were evaluated. Prostatic tissue was processed for measuring redox balance and histopathological examination. The BPH group had increased body and prostate weights, serum testosterone, dihydrotestosterone, PSA, and oxidative stress. Histologically, there were marked acinar epithelial and stromal hyperplasia, inflammatory infiltrates, and increased collagen deposition. An immunohistochemical study showed an increase in the inflammatory TNF-α and the proliferative PCNA markers. Treatment with DIA markedly decreased the prostate weight and plasma hormones, improved tissue redox balance, repaired the histological changes, and increased the proapoptotic caspase 3 expression besides the substantial reduction in TNF-α and PCNA expression. In conclusion, our study underscored DIA's potential to alleviate the prostatic hyperplastic and inflammatory changes in BPH through its antioxidant, anti-inflammatory, antiproliferative, and apoptosis-inducing effects, rendering it an effective, innovative treatment for BPH

    The design and the timeline of the study.

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    One of the most prevalent chronic conditions affecting older men is benign prostatic hyperplasia (BPH), causing severe annoyance and embarrassment to patients. The pathogenesis of BPH has been connected to epithelial proliferation, inflammation, deranged redox balance, and apoptosis. Diacerein (DIA), the anthraquinone derivative, is a non-steroidal anti-inflammatory drug. This study intended to investigate the ameliorative effect of DIA on the prostatic histology in testosterone-induced BPH in rats. BPH was experimentally induced by daily subcutaneous injection of testosterone propionate for four weeks. The treated group received DIA daily for a further two weeks after induction of BPH. Rats’ body and prostate weights, serum-free testosterone, dihydrotestosterone, and PSA were evaluated. Prostatic tissue was processed for measuring redox balance and histopathological examination. The BPH group had increased body and prostate weights, serum testosterone, dihydrotestosterone, PSA, and oxidative stress. Histologically, there were marked acinar epithelial and stromal hyperplasia, inflammatory infiltrates, and increased collagen deposition. An immunohistochemical study showed an increase in the inflammatory TNF-α and the proliferative PCNA markers. Treatment with DIA markedly decreased the prostate weight and plasma hormones, improved tissue redox balance, repaired the histological changes, and increased the proapoptotic caspase 3 expression besides the substantial reduction in TNF-α and PCNA expression. In conclusion, our study underscored DIA’s potential to alleviate the prostatic hyperplastic and inflammatory changes in BPH through its antioxidant, anti-inflammatory, antiproliferative, and apoptosis-inducing effects, rendering it an effective, innovative treatment for BPH.</div
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