272,875 research outputs found
[Report to W. P. Gannaway by T. T. Wardlaw, February 18, 1964 #3]
Criminal intelligence report by T. T. Wardlaw regarding an interview with Pierce Allman. Allman, who worked at a radio station, was watching the parade with Terrence Ford at the time that the President Kennedy was assassinated. He stated that he did not know Lee Harvey Oswald, Marina Oswald, or Jack Ruby
[Report to W. P. Gannaway by T. T. Wardlaw, February 18, 1964 #2]
Criminal intelligence report by T. T. Wardlaw regarding an interview with Pierce Allman. Allman, who worked at a radio station, was watching the parade with Terrence Ford at the time that the President Kennedy was assassinated. He stated that he did not know Lee Harvey Oswald, Marina Oswald, or Jack Ruby
He must have loved the earth, the sea, the sky,
Recited by Tommy Gosnell (in place of Mrs. Horace Smith) Springdale, Arkansas November 3, 1958
Reel 271, Item 27
To the Author of a Psalm
He must have loved the earth, the sea, the sky,
The powers that swing the universe along,
And all that is and has been and could be To sing so brave and beautiful a song.
He must have fingered ivory and jade And tasted with a discriminating tongue And deeped the glory that the man moon made,
A dim mysterious world that he was young.
He must have known the alchemy of life,
The day flooding in on waves of yellow mist,
Reclaiming from the oblivion night Drops of gold and wine of anethyst.
He must have loved this earth, yet he is dead.
Lifeless is his eager foot, his curious hand.
Or am I faithless?has he found instead A still more golden road to Smarkland?
Collected by Karl. T. Gosnell For Mary C. ParlerFunding for digitization provided by the Arkansas Humanities Council and the Happy Hollow Foundation
Wave turbulence of a rotating array of quantized vortices in the T → 0 temperature limit
The dynamics of quantized vortices in the zero temperature limit is currently of great interest, particularly in the case of the Fermi superfluid He-B. Here we study wave turbulence, generated by the librating motion of a rotating cylindrical container filled with He-B, in the limit of vanishing viscous forces at temperatures . The polarization of the quantized vortices with respect to the axis of rotation is measured using non-invasive NMR techniques. We observe a decrease of the polarization when the librating motion is started, and a two-stage relaxation process when the modulation of the rotation velocity is stopped. The first relaxation process is associated with the dissipation of large-scale flow stored in inertial waves and the solid body rotation of the vortex array. From the decay of these energy reservoirs we determine the rate of energy dissipation of large-scale flow. The later second process is related to the relaxation of Kelvin waves on individual vortices. This process is monitored by the recovery of the polarization. The existence of a Kelvin wave cascade at the lowest temperatures is currently a central open question. We supply some evidence for the cascade
Letter, [Author unclear] to Paulina T. Merritt
Handwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
Collaborative Art Practices in HE: Mapping and Developing Pedagogical Models
This project asks ‘How is interdisciplinary collaboration "taught" in HE institutions?’ and ‘What pedagogical models can be identified and developed?’
Performing and Creative Arts departments in HE institutions engage students in collaborative practice within a singular discipline or across disciplines, through interdisciplinary or hybridised art forms, as curricula or extra-curricula activity. Where students are engaged with interdisciplinary collaboration within the curriculum, tuition may involve case studies of collaborative partnerships, psychometric tests, a trial and error approach to throwing creative individuals together, or any combination of these.
This project aims to bring together ideas and modes of practices used in HE institutions and to present, as far as is possible, an overview of the current practices where interdisciplinary collaboration is a focal point of the learning activity.
In brief, and in the context of Performing and Creative Arts departments in HE institutions, this development project aims to:
Take a snapshot of current practice in HE
Construct typologies of modes of practice
Consider how pedagogies may be developed
Disseminate documentation setting out, and commenting on, pedagogical approaches to collaborative practic
Detrital zircon and apatite (U‐Th)/He geochronology of intercalated baked sediments: a new approach to dating young basalt flows
Simple numerical models suggest that many basaltic lava flows should sufficiently heat the sediments beneath them to reset (U‐Th)/He systematics in detrital zircon and apatite. This result suggests a useful way to date such flows when more conventional geochronological approaches are either impractical or yield specious results. We present here a test of this method on sediments interstratified with basalt flows of the Taos Plateau Volcanic Field of New Mexico. Nineteen zircons and apatites from two samples of baked sand collected from the uppermost 2 cm of a fluvial channel beneath a flow of the Upper Member of the Servilleta Basalt yielded an apparent age of 3.487 ± 0.047 Ma (2 SE confidence level), within the range of all published 40Ar/39Ar dates for other flows in the Upper Member (2.81–3.72 Ma) and statistically indistinguishable from the 40Ar/39Ar dates for basal flows of the Upper Member with which the studied flow is broadly correlative (3.61 ± 0.13 Ma). Given the high yield of 4He from U and Th decay, this technique may be especially useful for dating Pleistocene basalt flows. Detailed studies of the variation of (U‐Th)/He detrital mineral dates in sedimentary substrates, combined with thermal modeling, may be a valuable tool for physical volcanologists who wish to explore the temporal and spatial evolution of individual flows and lava fields.</p
[Affidavit by T. F. Bowley #1]
Handwritten affidavit by T. F. Bowley. Bowley states that a police officer had been shot as he drove to pick up his wife from work. He got out of his car and tried to help the officer, who seemed to be beyond help. Bowley used the squad car's radio to report the incident
[Affidavit by T. F. Bowley #2]
Photocopy of an affidavit by T. F. Bowley. Bowley states that a police officer had been shot as he drove to pick up his wife from work. He got out of his car and tried to help the officer, who seemed to be beyond help. Bowley used the squad car's radio to report the incident
The Role of c-FLIP in the Regulation of Apoptosis, Necroptosis and Autophagy in T Lymphocytes
To maintain homeostasis, T lymphocytes die through caspase–dependent apoptosis. However, blockage of caspase activity in T lymphocytes does not increase cell survival. The loss of caspase 8 activity leads to programmed necrosis (necroptosis) upon T cell receptor (TCR) stimulation in T lymphocytes. Necroptosis is correlated with excessive macroautophagy, an intracellular catabolic process characterized by the sequestration of cytoplasmic compartments through double–membrane vacuoles. Meanwhile, the proper induction of macroautophagy is required for T lymphocyte survival and function. Cellular caspase 8 (FLICE)–like inhibitory protein (c–FLIP) promotes survival in T lymphocytes. c–FLIP suppresses death receptor–induced apoptosis by modulating caspase 8 activation. Whether this modulation plays a role in the regulation of necroptosis has yet to be studied. Additionally, overexpression of c–FLIP reduces autophagy induction and promotes cell survival in cell lines. It remains unclear whether c–FLIP protects primary T lymphocytes by regulating the threshold at which autophagy occurs. In this study, c–FLIP isoform–specific conditional deletion models were used to study the role of c–FLIP in necroptosis and autophagy in primary T lymphocytes.Our results showed that the long isoform of c–FLIP (c– FLIPL) regulates necroptosis by inhibiting receptor interacting protein 1 (RIP–1). Upon TCR stimulation, c–FLIPL–deficient T cells underwent RIP–1–dependent necroptosis. Interestingly, though previous studies have generally described necroptosis in the absence of caspase 8 activity and apoptosis, pro–apoptotic caspase 8 activity and the rate of apoptosis were also increased in c–FLIPL–deficient T lymphocytes. Moreover, c– FLIPL–deficient T cells exhibited enhanced autophagy, which served a cytoprotective function. Apoptosis can be induced by either death receptors on the plasma membrane (extrinsic pathway), or the damage of the genome and/or cellular organelles (intrinsic pathway). Previous studies in c–FLIP–deficient T lymphocytes suggested that c–FLIP promotes cell survival in the absence of death receptor signals. Independent of death receptor signaling, mitochondria sense apoptotic stimuli and mediate the activation of caspases. Whether c–FLIP regulates mitochondrion–dependent apoptotic signaling remains unknown. Here, by deleting the c–Flip gene in mature T lymphocytes, we showed a role for c–FLIP in the intrinsic apoptosis pathway. In naïve T cells stimulated with the apoptosis inducer, c–FLIP suppressed cytochrome c release from mitochondria. Bim–deletion rescued the enhanced apoptosis in c–FLIP–deficient T cells, while inhibition of caspase 8 did not. Different from activated T cells, there were no signs of necroptosis in c–FLIP–deficient naïve T cells. Together, our findings indicate that c–FLIP is a key regulator of apoptosis, necroptosis and autophagy in T lymphocytes.</p
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