543 research outputs found
sj-pdf-1-prx-10.1177_00332941211040437 - Supplemental material for Investigating the Association Between Obsessive-Compulsive Disorder Symptom Subtypes and Health Anxiety as Impacted by the COVID-19 Pandemic: A Cross-Sectional Study
Supplemental material, sj-pdf-1-prx-10.1177_00332941211040437 for Investigating the Association Between Obsessive-Compulsive Disorder Symptom Subtypes and Health Anxiety as Impacted by the COVID-19 Pandemic: A Cross-Sectional Study by Athanasios Hassoulas, Katja Umla-Runge, Abeer Zahid, Olivia Adams, Madeline Green, Antonia Hassoulas and Eliana Panayiotou in Psychological Reports</p
Remediating rigid rule-following in subclinical obsessive-compulsive disorder using a brief mindfulness task: A case-control pilot study
A pioneering experiment by Hayes et al. (1986) demonstrated the influence of instructional control and rule-governed behaviour on sensitivity to alternating reinforcement schedules. Hassoulas et al. (2017) replicated the same experimental design in a sample of participants exhibiting obsessive-compulsive behavioural (OCB) traits, supporting the results reported by the original study but also providing further insights into the maintenance of rigid rule following in OCB. The current pilot study replicated the same experimental design and procedure once again, however in considering whether a brief mindfulness-based intervention would facilitate contact with schedule contingencies in a group of participants exhibiting OCB traits. A total of 78 participants were recruited, 38 of whom exhibited OCB traits as measured using the Maudsley Obsessive-Compulsive Inventory (MOCI). The results revealed a significant difference in sensitivity to changing schedules between the group of participants exhibiting OCB traits and those with few such traits (n=40), dependent on the degree of instructional accuracy they were provided with. The findings of the current study provide insights into the proposed concomitant administration of mindfulness-based interventions, alongside traditional first-line therapeutic modalities currently administered in the management of obsessive-compulsive disorder
The Δρομοδείχτης της Ελλάδος of 1824 and Athanasios Stageirites (Τίτλος περίληψης)
σ. [281]-290Κείμενο στα ελληνικά με περίληψη στα αγγλικά με τον τίτλο: The Δρομοδείχτης της Ελλάδος of 1824 and Athanasios StageiritesThe article first examines the close relationship between the publication “Δρομοδείχτης της Ελλάδος” [1824] and the publication “Ηπειρωτικά” (1819) by Athanasios Stageirites and then suggests that Athanasios Stageirites is the likeliest author of the “Δρομοδείχτης της Ελλάδος”.Δωδώνη: Τεύχος Πρώτο: επιστημονική επετηρίδα του Τμήματος Ιστορίας και Αρχαιολογίας της Φιλοσοφικής Σχολής του Πανεπιστημίου Ιωαννίνων; Τόμ. 43-44 (2014-2015
The modernisation of assessment in HE: AI as a disruptive catalyst for change
The COVID-19 pandemic demonstrated the truly disruptive effect that external forces can have on teaching and assessment in higher education, on a truly global scale. The pandemic also highlighted how such global events can serve as powerful catalysts, or accelerants, of innovation in higher education. Merely a few years post-pandemic, higher education is confronted with yet another global force: the emergence of artificial intelligence (AI), with implications that will resonate far beyond education alone. As we navigate this AI era, it is vital to consider its potential impact and applications in teaching and assessment. The popularity of open-access generative AI platforms, notably marked by ChatGPT's debut in November 2022, has initiated a transformative moment for assessment in higher education. It is essential that educators embrace AI to prepare both undergraduates and professional postgraduates for an evolving workplace. AI integration into assessment and teaching offers opportunities for innovation that can fundamentally reshape student preparation for professions demanding new skills and insights. This chapter addresses the challenges universities face in light of these emerging technologies, examining authenticity and academic integrity. We discuss the role of updated information literacy and digital competency strategies, focusing on AI, for both students and staff. Embracing new platforms and intelligent tools may enhance learning experiences through more authentic, less stressful evaluations of academic and vocational skills. AI integration will redefine both how and what we assess, requiring careful, ethical use to safeguard academic integrity while equipping graduates for contemporary professional demands
The role of stress in health and disease
Stress is a physiological and psychological response that is a fundamental component of human existence crucial to survival. The stress response is mediated by the hypothalamus and involves the activation of neural and endocrine systems. It plays a role in the normal, but at times pathological, functioning of immunological, gastrointestinal, cardiovascular, neurohormonal and nervous systems.
This chapter explores the adaptive stress response and considers the role that chronic stress plays in the pathophysiology of mental and physical illness
Dataset in support of the Southampton doctoral thesis 'The boatbuilding tradition of the Aegean during the Late Neolithic – Early Bronze Age periods. Typological classification, digital reconstruction and seakeeping assessment'
Dataset in support of the Southampton doctoral thesis 'The boatbuilding tradition of the Aegean during the Late Neolithic – Early Bronze Age periods. Typological classification, digital reconstruction and seakeeping assessment' Appendix D - Resistance data and Appendix C - Stability data.
This dataset is focused on two appendices:
Appendix D - Resistance data. D.1 Resistance data produced by the author via MAXSURF Resistance for this thesis.
Appendix C - Stability data
C1. Stability data – STIX and ISO criteria, produced by the author via MAXSURF Stability software for his thesis
This research was funded by Southampton Marine and Maritime Institute (SMMI), Vice-Chancellor's Scholarship, Greek Archaeological Committee UK (GACUK)
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The MSc Psychiatry at Cardiff University: introduction of new modules further supporting continuing professional development in psychiatry
The MSc Psychiatry at Cardiff University is an established postgraduate programme offering students a sound theoretical basis in psychiatry as a medical science and specialty. The programme currently offers six taught modules (focusing on mood and anxiety disorders, psychosis, old age psychiatry, forensic psychiatry, substance misuse, and child and adolescent psychiatry), as well as a dissertation module that students complete towards the end of the programme. In catering for the professional needs of clinical students and students pursuing careers in academia, two additional taught modules have been proposed exploring Leadership and Management in Psychiatry and Advances in Psychiatric Research. Feedback on the proposed introduction of the new modules was collated from the current full-time and part-time student cohorts
Peak power reduction algorithms in asymmetric digital subscriber line modems
Thesis (M.Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2000.Includes bibliographical references (leaves 94-96).This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.This thesis investigates peak-to-average ratio (PAR) reduction techniques for multicarrier modulation systems, such as discrete multitone (DMT) modems and orthogonal frequency-division multiplexed (OFDM) terrestrial broadcast transmitters. Through simulation and test implementation on a state-of-the-art programmable ADSL development platform, this thesis pursues a suitable solution for minimizing PAR given the resources of a programmable platform. This solution is integrated as a prototype implementation into a fully-functional ADSL modem and optimized for maximum PAR reduction performance within modem complexity constraints.by Athanasios Dimitri Dousis.M.Eng
Memantine for the treatment of obsessive-compulsive disorder: a systematic review and narrative synthesis
Objective
Obsessive-compulsive disorder (OCD) is a chronic psychiatric condition for which a substantial proportion of patients do not respond adequately to first-line treatments. This review thus aimed to critically appraise the clinical literature examining memantine in obsessive-compulsive disorder, with a particular focus on individual study design, dosing strategies, tolerability, and methodological limitations.
Methods
A structured literature search of MEDLINE was conducted in March 2024 from database inception to March 2024. Titles, abstracts, and full texts were screened against predefined inclusion criteria, and relevant studies were synthesised narratively. A second, identical literature search was conducted in August 2025 covering March 2024 to August 2025. In total, 10 studies were included in the narrative synthesis.
Results
Our findings suggest that memantine may offer therapeutic benefits for OCD. Methodological issues, however, such as small sample sizes, strong geographical clustering, the exclusion of dropout data and limited use of intention-to-treat analyses, restrict the generalisability of the reported outcomes. Tolerability varied significantly by dose, with higher doses being associated with increased side effects while lower doses appeared better tolerated but elicited a poorer efficacy, although evidence was mixed. Only one study rigorously assessed treatment-refractory OCD and reported significant symptomatic improvement following longer-term memantine administration. Baseline severity, treatment expectancy, and concurrent cognitive-behavioural therapy were also identified as factors that may mediate these effects.
Conclusion
Overall, current evidence does not support the routine use of memantine for OCD. However, it does highlight specific methodological considerations and priorities for future rigorous investigation. Future randomised controlled trials with larger samples, longer follow-ups, and standardised dosing protocols are needed to clearly determine memantine’s role in OCD management
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