317 research outputs found
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No full textThis document embodies a contract for the exchange of publishing and printing books between Muhammad Hassan Al-Azimi - Pakistan, and Muhammad Naguib Amin Al-Khanki - Egypt, also signed and dated.تعتبر هذه الوثيقة عقد تبادل نشر وطباعة الكتب بين محمد حسن العظيمي - باكستان، ومحمد نجيب أمين الخانكي - مصر، وموقع ومؤرخ أيضًا
Expression analysis of protein inhibitor of activated STAT (PIAS) genes in IFNβ-treated multiple sclerosis patients [Corrigendum]
No full textTaheri M, Azimi G, Sayad A, et al. J Inflamm Res. 2018;11:457–463.On page 457, Author list and Correspondence, the last author’s name was misspelt. The correct name is Soudeh Ghafouri-Fard.Read the original articl
Carpophilus truncatus Murray 1864
No full textCarpophilus truncatus Murray, 1864 Carpophilus floridanus Fall, 1910; Carpophilus halli Dobson, 1954. Distribution within Iran. Khuzestan (Azimi et al. 1993), Mazandaran (Sakenin et al. 2008 b), Markazi (Naeem & Akhyani 1988). Distribution outside Iran. Austria, China, Croatia, Czech Republic, Egypt, France, Germany, Greece, Italy, Japan, Morocco, Poland, Slovakia, Slovenia, Taiwan, Turkey. Cosmopolitan species.Published as part of Lasoń, Andrzej & Ghahari, Hassan, 2013, A checklist of the Kateretidae and Nitidulidae of Iran (Coleoptera: Cucujoidea), pp. 101-122 in Zootaxa 3746 (1) on page 107, DOI: 10.11646/zootaxa.3746.1.4, http://zenodo.org/record/22401
Epuraea luteola Erichson 1843
No full textEpuraea luteola Erichson, 1843 Nitidula intendens Walker, 1858; Nitidula submaculata Walker, 1859; Haptoncus pubescens Murray, 1864; Haptoncus testacea Murray, 1864; Epuraea vulpecula L. Redtenbacher, 1868; Haptoncus paupercula Reitter, 1873; Epuraea texana Crotch, 1874; Haptoncura subquadrata Reitter, 1877; Haptoncus albertisi Reitter, 1880; Haptoncus floreola Sharp, 1890. Distribution within Iran. Guilan, Mazandaran (Sakenin et al. 2008 b), Khuzestan (Azimi et al. 1993; Modarres Awal 1997 under Haptoncus luteola Erichson). Distribution outside Iran. Afghanistan, Albania, Andorra, Arab Emirates, Azerbaijan, Bosnia Herzegovina, Bulgaria, Canary Islands, China, Croatia, Cyprus, France, Germany, Greece, India, Iraq, Israel, Italy, Japan, Korea, Malta, Macedonia, Morocco, Nepal, Pakistan, Portugal, Romania, Saudi Arabia, Serbia and Montenegro, Slovenia, Spain, Taiwan, Turkey, Ukraine.Published as part of Lasoń, Andrzej & Ghahari, Hassan, 2013, A checklist of the Kateretidae and Nitidulidae of Iran (Coleoptera: Cucujoidea), pp. 101-122 in Zootaxa 3746 (1) on page 105, DOI: 10.11646/zootaxa.3746.1.4, http://zenodo.org/record/22401
Abstract 4384: Targeted sequencing reveals distinct and rare pathogenic variants in Caucasians with colorectal cancer
No full textAbstract
PURPOSE: Next-generation sequencing (NGS) is currently used to establish mutational profiles in many multigene diseases such as colorectal cancer (CRC) which is on the rise in many parts of the developing World including in the Middle East. Little is known about its genetic hallmarks in these populations. AIM: To identify variants in 15 CRC-associated genes in patients of Iranian descent.
METHODS: CRC specimens from 63 patients were used to establish the variants’ profile on an Ion Torrent platform by targeted exome sequencing. To rule out technical artifacts, the variants were validated in 13 of these samples using an Illumina NGS platform. Validated variants were annotated and compared to variants from publically available databases. An in-silico functional analysis was performed. MSI status of the analyzed samples was established. RESULTS: There were 51 validated variants distributed on 12 genes: 22% MSH3 (n=11/51), 10% MSH6 (n=5/51), 8% AMER1 (n=4/51), 20% APC (n=10/51), 2% BRAF (n=1/51), 2% KRAS (n=1/51), 12% PIK3CA (n=6/51), 8% TGFβR2A (n=4/51), 2% SMAD4 (n=1/51), 4% SOX9 (n=2/51), 6% TCF7L2 (n=3/51), and 6% TP53 (n=3/51). Most known and distinct variants were in mismatch repair genes (MMR, 32%) and APC (20%). Among oncogenes, PIK3CA was the top target (12%). MSH3 variants were more frequent and predominantly homozygous in the analyzed population.
CONCLUSION: These results illustrate for the first time CRC mutational profile in Iranian patients. MSH3, MSH6, APC and PIK3CA genes seem to play a bigger role in the path to cancer in this population. This is especially true for MSH3 variants that were very frequent and predominantly homozygous as these will associate with the EMAST phenotype that has prognostic implications. These findings will potentially lead to informed genetic diagnosis protocol and targeted therapeutic strategies.
Citation Format: Pooneh Mokarram, Sudhir Varma, Hamed Azimi, Hasti Olumi, Ali reza Safarpour, Michael Nickerson, Hassan Brim, Hassan Ashktorab. Targeted sequencing reveals distinct and rare pathogenic variants in Caucasians with colorectal cancer [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 4384. doi:10.1158/1538-7445.AM2017-4384</jats:p
Urophorus humeralis Fabricius 1798
No full textUrophorus humeralis (Fabricius, 1798) Carpophilus punctatus Fleutiaux, 1887; Carpophilus rickseckeri Fall, 1910. Material examined. Kerman, Shahdad, 60 km NE Kerman, 1. v. 2010, 2 spec., lgt. et coll. K. Orszulik. Distribution within Iran. Khuzestan (Azimi et al. 1993; Modarres Awal 1997 under C. humeralis Fabricius), Iran (no locality cited) (Williams et al. 1983; Audisio et al. 2000). Distribution outside Iran. Cosmopolitan. Subfamily Cryptarchinae C.G. Thomson, 1859 Genus Cryptarcha Shuckard, 1840 Cryptarcha incognita Iablokoff-Khnzorian, 1966 Distribution within Iran. Fars (Audisio 1993 b). Distribution outside Iran. Armenia. Subfamily Nitidulinae Latreille, 1802 Genus Nitidula Fabricius, 1775 Nitidula carnaria (Schaller, 1783) Nitidula quadripustulata Fabricius, 1792; Nitidula guttalis Herbst, 1793; Nitidula variata Stephens, 1830; Nitidula flavipennis Heer, 1841. Material examined. Mazandaran, 15 km E of Baladeh, vic. Valashid, 36 ° 12´13 ´´ N, 51 ° 52´31 ´´ E, 1980 m, 7.v. 2010, A. Weigel leg., 1 spec. (NKME). Distribution within Iran. East Azarbaijan (Sakenin et al. 2011), Tehran (Jelínek 1981; Audisio et al. 2000). Distribution outside Iran. Holarctic.Published as part of Lasoń, Andrzej & Ghahari, Hassan, 2013, A checklist of the Kateretidae and Nitidulidae of Iran (Coleoptera: Cucujoidea), pp. 101-122 in Zootaxa 3746 (1) on page 108, DOI: 10.11646/zootaxa.3746.1.4, http://zenodo.org/record/22401
Isolation of resonance in acoustic backscatter from elastic targets using adaptive estimation schemes
No full textThe problem of underwater target detection and classification from acoustic backscatter is the central focus of this paper. It has been shown that at certain frequencies the acoustic backscatter from elastic targets exhibits certain resonance behavior which closely relates to the physical properties of the target such as dimension, thickness, and composition. Several techniques in both the time domain and frequency domain have been developed to characterize the resonance phenomena in acoustic backscatter from spherical or cylindrical thin shells. The purpose of this paper is to develop an automated approach for identifying the presence of resonance in the acoustic backscatter from an unknown target by isolating the resonance part from the specular contribution. An adaptive transversal filter structure is used to estimate the specular part of the backscatter and consequently the error signal would provide an estimate of the resonance part. An important aspect of this scheme lies in the fact that it does not require an underlying model for the elastic return. The adaptation rule is based upon fast Recursive Least Squares (RLS) learning. The approach taken in this paper is general in the sense that it can be applied to targets of unknown geometry and thickness and, further, does not require any a priori information about the target and/or the environment. Test results on acoustic data are presented which indicate the effectiveness of the proposed approach.The work of M. R. Azimi-Sadjadi was supported by the ASEE-ONR program under the High Area Rate Recon. Project. The work of J. Wilbur and G. J. Dobeck was supported by the ONR
Investigation of Different Factors Affecting Asphalt Cement Ageing and Durability
No full textAsphalt cement is an organic material and, like any other organic material tends to react with atmospheric oxygen, thus changing its physical properties (more accurately rheological properties) gradually over time. Although there is no doubt that chemical changes happen in asphalt cement due to gradual oxidation, it is not the only factor resulting in changes in asphalt cement properties over time. Other factors such as loss of volatiles, the selective absorbance of lighter oily molecules by the aggregates’ surface, molecular reorientation, and so forth, could lead to changes in asphalt cement properties, most of which result in hardening. The alteration in physical properties of asphalt cement during construction and its performance period is called ageing.
The severity of the age-hardening significantly depends on environmental factors such as temperature, latitude (which affects the angle of sunshine radiation), humidity, ultraviolet, etcetera, as well as mixture properties (such as aggregate gradation, aggregate type, air-void distribution, filler composition, and additive’s properties). There are several conditioning procedures to simulate short- and long-term ageing for both asphalt cement and mixes. Unfortunately, most of the existing methods are using excessively high conditioning temperatures and not realistic conditioning parameters.
This project aims to identify the importance of less considered factors, such as the possible catalytic effect of minerals, solar radiation, and humidity conditioning and to define a laboratory long-term age conditioning procedure for asphalt mixes by considering different affecting factors to enable designers to include an ageing mechanism in their predictions.
To reach to the goals of this project, compacted asphalt mix samples prepared using aggregates with different petrology and conditioned using standard (AASHTO R30) procedure and bespoke methods to include as much as environmental factors as possible. Complex (Dynamic) Modulus test will be used to evaluate the changes in the rheological behaviour of mixes. The 2S2P1D model fitted on laboratory results and used to investigate the rheological behaviour. Asphalt cement of the conditioned mixes extracted for further investigation on the rheological and chemical changes in asphalt cement. Frequency sweep test performed on extracted asphalt cement and results were processed using the 2S2P1D model. FT-IR spectroscopy was also used to investigate the change in the chemistry of asphalt cement by following the changes in carbonyl and sulfoxide indices and the ratio between them. Thermal sensitivity of rheological properties of both asphalt mix and asphalt cement was also investigated using time-temperature superposition shift-factors and utilizing Arrhenius and William-Landel- Ferry (WLF) theorems to further investigate the effect of different age conditioning and aggregates.
Results of this research confirmed the effect of iron sulphide oxidation products in altering the chemistry of changes during ageing, while it didn’t capture significant acceleration in the process. Moreover, it was found that the coupling water treatment with solar radiation can effectively age asphalt mix samples and the product of ageing using these parameters are considerably different from extended heating procedures
Investigation of the Implementation Rate of Semantic Web Technology in Knowledge Management Software
No full text1. IntroductionThe explosive growth of information and lack of structuring of information and the problems of information retrieval caused the emergence of the third generation of the web. The third generation of the web, which was called the semantic web, sought the connection between humans and computers and tried to make information understandable to machines. The Semantic Web, an extended version of the current Web, provides a standard structure for representing and reasoning with data. The semantic web is about sharing data and facts, not sharing the text of a page. The Semantic Web helps build the technology stack to support the "Web of Data" rather than the "Web of Document". The ultimate goal of the Web of Data is to enable computers to perform meaningful tasks and to develop systems that can support reliable network interactions (Patel & Sarika, 2021). Semantic web technologies can be used in various fields such as data integration, skill-finding, online think tanks, serving multimedia collections, and so on. Semantic web technologies can be used in various fields such as data integration, skill finding, online think tank, serving multimedia collections, and such things.It seems that the use of the semantic web in KM software will certainly be effective in providing useful information. In KM, various software appeared, which in the context of KM, play an important role in the field of registration, distribution and sharing, application and use of information and knowledge, automation of processes, reduction of costs of acquisition, creation, organization, and application of a large amount of information and knowledge without time and place restrictions for people in organizations and companies, and causes changes in the methods of production, transfer and use of knowledge in them and prevent the entry and exit of unrelated and repetitive information and knowledge and improper processing of information and knowledge. Therefore, the aim of the current research is to investigate the implementation of semantic web technology in KM software.2. Literature Review Over the past few decades, many technologies related to the Semantic Web have appeared or been developed. The World Wide Web Consortium (W3C), which works intensively on semantic standards, has endorsed the Resource Definition Framework (RDF) and the OWL Web Ontology Language (OWL), which provide a solid foundation for building semantic enterprise applications and Moving the Semantic Web from the research level partially led to its becoming the industry standard needed to build next-generation applications (Tjoa et al., 2005).The Semantic Web is an extension of the current Web that improves machine-human interaction by giving information clear meaning. The idea of the Semantic Web is to hand over most of the tasks and decision-making to machines. This is made possible by adding knowledge to web content through machine-understandable language and creating intelligent software agents that can process this information. The Semantic Web, on the other hand, consists of structured information and explicit metadata, paving the way for rapid access to information and semantic search capabilities (Hassanzadeh & Keyvanpour, 2012). The semantic web was first introduced in 1988 by Tim Bernersley, known as the father of the web. But its definition was officially presented including seven-layer architecture in 2001. These seven layers include (URL), XML, (RDF), (Ontology), (Proof Layer), (Logic Layer) and (Trust Layer) (Gerber, Barnard & Van der Merwe, 2007).The structure of the semantic web is a way of organizing data in a descriptive technology, RDF, which specifies data sources and their relationships, and identifies or names the resource's URAs, and OWL describes specifications. and data classes with a common language. Sparquel is a query language that searches RDF data. Another part of the Semantic Web is making sure that different databases use the same vocabulary to describe everything (Azimi & Rafieinasab, 2022).3. MethodologyThe current research is applied, using a survey method and a descriptive approach. The statistical population of the current research is three KM software, which includes Dana KM software, Nedak comprehensive KM system, and MTA share software, which were investigated and analyzed. The data collection tool was also a checklist using a yes/no scale. After collecting the data and in order to confirm that the criteria of the Semantic Web, the checklist (questionnaire) was provided to the experts, and using their opinion, the presence or absence of the application of the Semantic Web capabilities in the KM software was confirmed. Finally, the obtained data were analyzed in Excel software.4. ResultsTherefore, the present study shows that the architecture of semantic technology in all six layers (URL, XML, RDF, ontology, metadata, and logic) in all three software (Dana KM software, Nedak's comprehensive KM system, and MTA share software) is used and at a favorable level. But the semantic tools for searching and retrieving information in all three layers (ontology, RDF, metadata) in these types of software have not been used much and have not been paid attention to.5. ConclusionThe results show that it is necessary to pay more attention to the application of semantic technology architecture in the comprehensive KM system software of Nadak and MTA share and to use them in all the mentioned layers. It is also necessary to use semantic tools for searching and retrieving information in any software called Dana KM, Nedak Comprehensive KM System in all layers (ontology, RDF, and metadata). In the field of application of web technology architecture, Dana's KM software is at a favorable level compared to the other two software
1938 revisited? Should doors open wider to Syrian refugees?
No full textDoes it seem that every time the world watches refugees flee violence and persecution while politicians claim their country can\u27t possibly take in asylum seekers, we lamentingly claim that the world will never again turn its back on these people.
And yet the next time we seem people streaming out of a war zone with nothing but their families and the shirts on their back we forget the promise we made the last time this happened?
For a world that promised \u27Never Again\u27 after World War II, how much have we actually learned from the handling of refugee crises of the past? Are we making the same mistakes over and over again?
Do you see echoes of the treatment of Jews fleeing the Holocaust in government rhetoric about refugees from Syria and Iraq? And if so, what explains this short-sightedness?
Guests
Dai Le, Founder of DAWN (Diverse Australasian Women’s Network)
Professor Klaus Neumann, Historian at Swinburne University and author of Across the Seas: Australia\u27s Response to Refugees: A History
Akram Azimi, Sociologist at the University of Western Australia and 2013 Young Australian of the Yea
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