729 research outputs found
Mushroom-like soft fibromas on the chronic lymphedema of the legs
No full textThis article is not an exact copy of the original published article in European Journal of Dermatology. The definitive publisher-authenticated version of Satoshi Nakamura, Yoshio Hashimoto, Kaoru Nishi, Keiko Takeda, Hidetoshi Takahashi, Toshihiro Mizumoto, Hajime Iizuka, European Journal of Dermatology, 20(2), 228-229. is available online at: http://www.jle.com/en/revues/medecine/ejd/e-docs/00/04/55/B2/article.phtml
On the description of nature and the feeling of Kaoru, the hero in the Tale of Genji, to Uji
No full text源氏物語の宇治の自然描写は、登場人物の心情と関連している。都と宇治の環境の違い、宇治の姉妹との人間関係、描写される音楽から、薫の精神的探求を述べる。The author researches a visit made by Kaoru, the hero in the Tale of Genji, to Uji, a suburb of Kyoto. This paper analyses; 1) the differences in the atmosphere of Uji and Kyoto. 2) the interaction between Kaoru and the beautiful sisters he meets when hearing heavenly music, and 3) the effect of this encounter on the mind of the hero himself
丸山薫とリルケ : 『物象詩集』の方法
No full textAlthough he was one of the representative poets of the Showa Era (1925-1989), Maruyama Kaoru has not fully attracted researchers' attention. He established a unique poetic world by "Bussho Shishu", the collection of poems of his own selection, published in 1941. He stated that his motivation to compose poems was rooted in "a tantalizing desire for objects and nostalgic emotions to them". The author assumes his method of introducing feelings into objects derived from Rainer Maria Rilke. Hori Tatsuo and Tachihara Michizo have often been regarded as the Japanese poets most strongly influenced by Rilke. In this paper, the author attempts to make clear that Maruyama Kaoru also cultivated his new lyric style under the influence of Rilke, focusing on his "Horui" and "Mizu no Kokoro".海老井英次教授退官記念号〈Special Issue〉dedicated to Professor EBII Eij
A clinical study of prostatic carcinoma
No full textSeventy seven patients with prostatic carcinoma were treated in our clinic between 1977 and 1986. Most of them were treated by a hormonal agent as the first therapy. None of the 9 stage A1 cases showed any reactivation, but 4 of the 5 stage A2 cases relapsed to metastatic disease. The chemotherapy performed in 3 of the 4 reactivated cases had no obvious effect on the disease. Seven of the 8 patients with stage B disease were alive without relapse. Relapse was seen in the other patient who had poorly differentiated carcinoma and chemotherapy in this case resulted in stable disease for the present. Four of the 15 stage C cases including 3 poorly differentiated carcinomas were hormone resistant or reactivated. For these resistant cases radiotherapy and/or the chemotherapy were performed, but a response was seen in only one case. Consequently, the first therapy for stage A2, B and C of poorly differentiated carcinoma must be improved. Of the 40 stage D cases, 4 patients who were treated by an early combination of hormonal therapy and chemotherapy had a better prognosis than the others. These 4 patients had poorly differentiated carcinomas with multiple bone metastases. Two of these 4 patients were alive without relapse for 17 and 72 months, and one of the 2 patients with relapse was also alive for 75 months. We believe that early chemotherapy is the key for better prognosis in stage D cases
Clinical effects of oxybutynin hydrochloride (Pollakis)--especially in the treatment of pollakisuria, urgency and urinary incontinence
No full text神経因性膀胱をはじめとして頻尿, 尿意切迫感および尿失禁を主訴とする患者を対象として塩酸オキシブチニンを投与し, 臨床症状を中心にその有効性, 安全性につき検討した.1)総症例数52例中44例が4週以上の投与を完了した.平均投与期間は66.8日であった.2)投与量別全般改善度を評価した成績は2 mg×3回群で"改善"以上の改善率は55%, "やや改善"以上が85%であり, 3 mg×3回群でそれぞれ68.2%, 95.5%であった.また1日2回投与でも臨床症状のコントロールが可能な症例を認めた.3)副作用は評価対象52例中2例に認められ, 2例とも口渇のみであり, 臨床上問題となる重篤なものはなかった.4)有用度は評価時において, "有用"以上67.3%, "やや有用"以上88.5%と高い有用率が得られたThe effects and the safety of oxybutynin hydrochloride were investigated in 52 patients, 17 male and 35 female, with the chief complaints of pollakisuria, urgency and urinary incontinence. Clinical responses to the drug were assessed mainly by the subjective symptoms of the patients. The diagnoses of these patients were neurogenic bladder in 17, unstable bladder in 16 and others in 19 patients. The average administration period was 66.8 days. The rate of global improvement (excellent and good) was 55% in the 2 mg dose given 3 times daily group, 68.2% in the 3 mg dose given 3 times daily group. Side effects, such as dry mouth, were observed in 2 of the 52 patients (3.8%), but no serious side effects were observed. The rate of global utility (remarkable and moderate) was 67.3%. These data indicate that oxybutynin hydrochloride seems to be useful and safe for the treatment of pollakisuria, urgency and urinary incontinence
Diffusion of sulbactam and cefoperazone into the prostatic tissue
No full text前立腺摘除術を受けた20症例にSBT/CPZを2 g投与し, 1時間後に血清および前立腺組織内について同一の条件下で採取し, SBT, CPZ濃度を測定した.1)血清濃度はCPZの方がSBTより有意に(p<0.01)高値に維持されていた.2)前立腺組織内濃度はCPZの方がSBTより有意に(p<0.05)高かった.3)前立腺組織内移行性は2剤間で異なり, 対血清比はSBTの方がCPZより有意に(p<0.05)高かったDiffusion of sulperazone (SBT) and cefoperazone (CPZ) into the prostatic tissue was studied in 20 cases. Two g of SBT/CPZ was injected intravenously and 1 hour later, prostatic tissue was obtained surgically and venous blood was drawn simultaneously. The serum concentration of CPZ (58.0 micrograms/ml +9.2) was higher than that of SBT (25.9 micrograms/ml +/- 9.3) and the prostatic tissue concentration of CPZ (14.9 micrograms/ml +/- 6.1) was higher than that of SBT (10.9 micrograms +/- 6.1). However, the SBT concentration ratio of prostatic tissue to serum level (P/S ratio) was significantly higher (42.5%) than that of CPZ (25.9%). The SBT concentration in the prostatic tissue was high enough to enhance the antibacterial activity of CPZ. SBT/CPZ was appraised to be an effective chemotherapeutic agent for infections of prostate caused by susceptible organisms, especially by beta-lactamase producing bacteria
- …
