3,019 research outputs found
Licklider Correspondence
Correspondence between Kevin Lynch and J.C.R. Licklider regarding the proposed topic of study. The study discussed became the Perceptual Form of the City, a research project investigating the individual’s perception of the urban landscape
Assessing the effectiveness of business support services in England: evidence from a theory based evaluation
In England, publicly supported advisory services for small firms are organised primarily through the Business Link (BL) network. Based on the programme theory underlying this business support services we develop four propositions and test these empirically using data from a new survey of over 3,000 English small firms. Our empirical results provide a broad validation of the programme theory underlying BL assistance for small firms in England during 2003, and more limited support for its effectiveness. More specifically, we find strong support for the value of BL operators maintaining a high profile as a way of boosting take-up. We also find some support for the approach to market segmentation adopted by BL allowing more intensive assistance to be targeted on younger firms and those with limited liability status. In terms of the outcomes of BL support, and allowing for issues of sample selection, we find no significant effects on growth from ‘other’ assistance but do find positive and significant employment growth effects from intensive assistance. This provides partial support for the programme theory assertion that BL support will lead to improvements in business growth performance and stronger support for the proposition that there would be differential outcomes from intensive and other assistance. The positive employment growth outcomes identified here from intensive assistance, even allowing for sample selection, suggest something of an improvement in the effectiveness of the BL network since the late 1990s
Religion, eroticism and being's continuity : a reading of Kevin Hart in the light of Bataille's theory
Zhang explores how poet Kevin Hart's writing is resonant with Bataille's theory on religion and eroticism, and demonstrates, in the meantime, the ways of obtaining intimacy with the deity, or continuity of being, by reading two of his major poems, "The Hall" (Hart, Flame Tree 192-4) and "Madonna" (195-200), with some references to Bataille's works, including The Impossible, Story of the Eye, and L'ABBE C. Understanding religion and eroticism in this way, they find that Bataille's theory is admirably re-embodied in some of Hart's poems, especially in "The Hall" and "Madonna," in which the poet, as Bataille does, submits, in an academic or philosophical way, the divine "totality" and "transcendent beyond" into interrogation
Children and Disasters: A tribute to Professor Kevin Ronan
(c) The Author/sIn 1997, Professor Kevin Ronan published a paper in the first ever edition of the Australasian Journal of Disaster and Trauma Studies, titled “The Effects of a “Benign” Disaster: Symptoms of Post-traumatic Stress in Children Following a Series of Volcanic Eruptions”. Over the next 23 years, Kevin and his many colleagues pursued aspects of children and disasters to both improve practice and advance scholarship in this area. In March 2020 we were saddened by the untimely passing of Kevin. As a tribute to Professor Ronan this special issue of the Australasian Journal of Disaster and Trauma Studies brings together accounts of current research and practice initiatives inspired by, building upon, and directly influenced by Professor Ronan’s work
Incorporation of a-linolenic acid and linoleic acid into human respiratory epithelial cell lines
Animal and human studies designed to examine the effects of α-linolenic acid (ALA) and linoleic acid (LA) supplementation on the fatty acid composition of plasma and tissues have demonstrated a marked difference in incorporation into phospholipids of these 18-carbon precursors of the long-chain polyunsaturates. Whereas tissue phospholipid levels are linearly related to dietary ALA and LA, the levels of tissue LA can be 10-fold higher than tissue ALA even when dietary levels are equivalent. There is some dispute whether this disparity is due to ALA being more rapidly metabolized to its products or substantially oxidized by the liver, or whether LA but not ALA is readily incorporated into cellular phospholipids. We examined the level of incorporation of polyunsaturated fatty acids into human respiratory epithelial cell lines (A549, 16HBE) by determining the dose-dependent incorporation of ALA and LA as free fatty acid (5–150 μg FFA/mL). Cell membrane phospholipid ALA and LA were both increased up to ∼20–30% total fatty acids, with a concomitant decrease predominantly in monounsaturated membrane fatty acids, before significant toxicity was observed (50 μg/mL). Our data support the concept that rather than any inherent inability by human cells to incorporate ALA into membrane phospholipids, the lack of ALA content in human and animal tissues in vivo is due to the rapid metabolism or oxidation of this fatty acid in the liver.Dani-Louise Bryan, Prue Hart, Kevin Forsyth and Robert Gibso
Modulation of respiratory syncytial virus-induced prostaglandin E(2) production by n-3 long-chain polyunsaturated fatty acids in human respiratory epithelium
Infection with respiratory syncytial virus (RSV) results in substantial infant morbidity and has been associated with the subsequent development of childhood asthma. Inflammatory mediators produced by both the epithelium and tissue leukocytes during RSV infection stimulate the release of chemotactic factors by the respiratory epithelium and the subsequent influx of inflammatory cells, predominantly neutrophils. We investigated the production of inflammatory mediators [prostaglandin E ₂ (PGE ₂), interleukin (IL)-1β, tumor necrosis factor α] and chemokines [IL-8, RANTES (regulation on activation, normal T cell expressed and secreted)] by alveolar epithelial cells in response to RSV infection. Infection of a human alveolar epithelial transformed cell line (A549 cells) with live RSV substantially increased production of PGE ₂, IL-8, and RANTES. By altering cell membrane FA through incorporation of the long-chain PUFA (LCPUFA) arachidonic acid, EPA, and DHA, we were subsequently able to significantly modulate PGE ₂ production by the infected epithelium. Because of the dynamic nature of the effects of PGE ₂ on lung function, regulation of this prostaglandin during RSV infection by n-3 LCPUFA has the potential to significantly alter the disease process.Dani-Louise Bryan, Prue Hart, Kevin Forsyth and Robert Gibso
The dramatising of theology : humanity’s participation in God’s drama with particular reference to the theologies of Hans Urs von Balthasar and Karl Barth
The aim of this project is to investigate the proper response of theology to the Christian God who, as revealed through revelation, is Being-in-act. This project takes seriously the idea posited by Shakespeare, that totus mundus agit histrionem, and upon this stage ‘all the men and women merely players: They have their exits and their entrances; and one man in his time plays many parts.’ If, then, God’s Being is in act, and as so many have deduced, life and death are enveloped within the drama of everyday, then, might it be possible that our theological endeavours would prosper through a dramatic rendering? In light of this, the project seeks to illumine that it is beneficial for both the Church and society, to realise how drama can be, and is, fruitful for our theological endeavours. God is Being-in-act, and through His revelation, He invites humanity to enter into and participate in His action. In light of the aforementioned, then, theology must contend with the implications for its practices, which, as is being argued, are benefited most through a full embrace of the dramatising of theology.
The thesis is situated in the recent movement of our theological endeavours that recognise the profundity of the dramatic and its ability to illuminate God’s action and call to action from theology, the Church and society. Moving forward from the seminal work of Hans Urs von Balthasar, and set forth in the context of the theologies of Balthasar and Karl Barth, this project argues that it is through the dramatising of theology that theology is best equipped to illumine God’s desire for humanity’s participation in His Theo-drama. The dramatising of theology is a natural response to God’s Being-in-act; it is the natural movement of theology’s response to God’s action which calls for an active response on our part. Current examples of today’s theological movement towards the dramatic can be seen in such authors as Max Harris, Trevor Hart, Stanley Hauerwas, Michael Horton, Todd Johnson and Dale Savidge, Ben Quash, Kevin Vanhoozer, Samuel Wells and N.T. Wright. This project hopes to contribute to the movement towards the dramatising of theology
Room-temperature Cu(II) radical-triggered alkyne C–H activation
A dimeric Cu(II) complex [Cu(II)2L2(μ2-Cl)Cl] (1) built from an asymmetric tridentate ligand (2-(((2-aminocyclohexyl)imino)methyl)-4,6-di-tert-butylphenol) and weakly coordinating anions has been synthesized and structurally characterized. In dichloromethane solution, 1 exists in a monomeric [Cu(II)LCl] (1′) (85%)–dimeric (1) (15%) equilibrium, and cyclic voltammetry (CV) and electron paramagnetic resonance (EPR) studies indicate structural stability and redox retention. Addition of phenylacetylene to the CH2Cl2 solution populates 1′ and leads to the formation of a transient radical species. Theoretical studies support this notion and show that the radical initiates an alkyne C–H bond activation process via a four-membered ring (Cu(II)–O···H–Calkyne) intermediate. This unusual C–H activation method is applicable for the efficient synthesis of propargylamines, without additives, within 16 h, at low loadings and in noncoordinating solvents including late-stage functionalization of important bioactive molecules. Single-crystal X-ray diffraction studies, postcatalysis, confirmed the framework’s stability and showed that the metal center preserves its oxidation state. The scope and limitations of this unconventional protocol are discussed
Continuous metadata flows for distributed multimedia
The practical use of temporal multimedia has increased markedly in recent years as enabling technologies for the distribution and streaming of media have become available. As a part of this trend, hypermedia systems and models have adapted accordingly to incorporate such distributed multimedia for presentation. Structured interpretation of information has long been a fundamental feature of both open hypermedia systems and knowledge systems. Metadata, in its many forms, has become the cornerstone for providing this structured knowledge above and beyond basic data and information. This thesis presents the rationale and requirements for continuous metadata, which supports the metadata accompanying distributed multimedia throughout the lifecycle of streamed media, from generation, through distribution, to presentation. Throughout this process it is the temporal and continuous nature of the metadata which is paramount. A conceptual framework for continuous metadata is proposed to encapsulate these principles and ideas. Continuous metadata and the associated framework enable the development, in particular, of real-time, collaborative, semantically enriched distributed multimedia applications. Experience building one such system using continuous metadata is evaluated within the framework. An ontology is developed for the system to enable the collation, distribution, and presentation of structure aiding navigation of multimedia, and it is shown how continuous metadata utilising the ontology can be distributed using multicas
Prospectus, February 25, 1972
FOUNDATION BECOMES A REALITY; P. C. Student Achievement Winners; Ford Foundation Scholarship Awarded; New Course Offered; Nelson To Speak At U. of K.; The Editor\u27s View: Yes!, S.I.U. Where The Action Is; What\u27s Going On: Registration Time Schedule Spring Quarter 1971-72, Drug Week Planned, Disadvantaged Student Workshop; Counselor\u27s Corner: Mount Senario College, S.I.U., Evening Counseling, Pre-reg.; Parkland Notices: Veterans, Illinois Grant, Ski Club, Pre-Reg., Yearbook, Law Enforcement, Student Gov\u27t, LRC; Editorial Cartoons: Women\u27s Lib vs Men\u27s Lib, Politics and \u27The War\u27, Ecologically Speaking, Easy Dialing?, Don\u27t Get Sick!, Freedom, Love thy Neighbor, The Real State Of The Union?; Kevin On Environment; Black Genesis; Wiese Films at The Dream Museum; They Were Here; MEM-Brain; Portrait Painting Class; Orpheus Reborn: fall, Doorman, Time, Damned!; Movie Reviews: Crime is Bloody; Reflections; Hart Beat; Wrestlers Eye National; Cobra Statistics; Intercollegiate Women\u27s Basketball; IM Basketball Standings; Cobra Basketball Recordhttps://spark.parkland.edu/prospectus_1972/1010/thumbnail.jp
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