9 research outputs found

    Social practice in the legal secretariat of the municipality of Bucaramanga to monitor and control court rulings on class actions duly enforced in the second instance, for which the infrastructure secretariat has been designated for compliance from September 19, 2004, to July 31, 2025.

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    Título: Practica social en la secretaría jurídica del municipio de Bucaramanga para realizar el seguimiento y control de los fallos judiciales de acciones populares debidamente ejecutoriados en segunda instancia que para su cumplimiento se haya designado a la secretaría de infraestructura desde el 19 de septiembre de 2004 hasta el 31 de julio de 2025. Autor: Gamaliel Eliu Garcia Rojas Palabras Clave: Sistema Jurídico Integral, SAMAI, Consulta de Procesos Nacional Unificada Descripción: El Municipio de Bucaramanga es un ente territorial encargado del desarrollo y el mejoramiento de la calidad de vida de sus habitantes, basado en la efectividad, transparencia y legalidad, prestando oportuna y eficientemente servicios a los diferentes sectores de la comunidad, acorde a las necesidades de la ciudadanía, las exigencias del medio y el cumplimiento de la Constitución y las Leyes, fomentando el autocontrol y la autogestión, para alcanzar la satisfacción de los usuarios. Centrada en un sistema de gerencia participativa, garantizando la identificación y la prevención de las condiciones y factores que afectan la salud y seguridad de los servidores públicos, para garantizar un ambiente de trabajo adecuado, el uso eficiente de los recursos y el compromiso para estar a la vanguardia en conocimientos, técnicas y metodologías que contribuyan al desarrollo de la competitividad y continua del Sistema Integrado de Gestión de Calidad. En el marco de sus competencias el municipio de Bucaramanga debe propender por la defensa judicial en todas sus dependencias y la prevención del daño antijurídico, en ese sentido, esta práctica en la secretaría jurídica busca identificar falencias y corregirlas en el cumplimiento de los fallos judiciales producto de acciones populares ejecutoriadas en segunda instanciaPregradoAbogadoTitle: Social practice in the legal secretariat of the municipality of Bucaramanga to monitor and control court rulings on class actions duly enforced in the second instance, for which the infrastructure secretariat has been designated for compliance from September 19, 2004, to July 31, 2025. Author: Gamaliel Eliu Garcia Rojas Key Words: Comprehensive Legal System, SAMAI, Unified National Process Inquiry Description: The Municipality of Bucaramanga is a territorial entity responsible for the development and improvement of the quality of life of its inhabitants, based on effectiveness, transparency, and legality, providing timely and efficient services to different sectors of the community, in accordance with the needs of citizens, the demands of the environment, and compliance with the Constitution and laws, promoting self-control and self-management to achieve user satisfaction. Focused on a participatory management system, it guarantees the identification and prevention of conditions and factors that affect the health and safety of public servants, to ensure an adequate work environment, the efficient use of resources, and a commitment to being at the forefront of knowledge, techniques, and methodologies that contribute to the development of competitiveness and the continuity of the Integrated Quality Management System. Within the scope of its powers, the municipality of Bucaramanga must strive for legal defense in all its departments and the prevention of unlawful damage. In this regard, this practice in the legal secretariat seeks to identify shortcomings and correct them in compliance with court rulings resulting from popular actions enforced in the second instance

    Evaluating Alzheimer’s disease progression by modeling crosstalk network disruption

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    Aβ, tau and P-tau have been widely accepted as reliable markers for Alzheimer’s disease (AD). The crosstalk between these markers forms a complex network. AD may induce the integral variation and disruption of the network. The aim of this study was to develop a novel mathematic model based on a simplified crosstalk network to evaluate the disease progression of AD. The integral variation of the network is measured by three integral disruption parameters. The robustness of network is evaluated by network disruption probability. Presented results show that network disruption probability has a good linear relationship with Mini Mental State Examination (MMSE). The proposed model combined with Support vector machine (SVM) achieves a relative high 10-fold cross-validated performance in classification of AD vs normal and mild cognitive impairment (MCI) vs normal (95% accuracy, 95% sensitivity, 95% specificity for AD vs normal; 90% accuracy, 94% sensitivity, 83% specificity for MCI vs normal). This research evaluates the progression of AD and facilitates AD early diagnosis

    La postura de garante de los altos funcionarios como criterio configurador del delito de homicidio doloso en las manifestaciones sociales

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    El presente trabajo de investigación tiene como fin determinar criterios jurídicos en la postura de garante de los altos funcionarios, a partir del análisis y verificación del estatus que poseen, en razón del cargo, como criterio configurador del delito de homicidio doloso en las manifestaciones sociales. La tesis explora-como referencia-la denuncia constitucional N°1502020, en contra del ex Presidente Merino de Lama, como presunto autor del delito en cuestión. De ahí que, se estudió el delito de omisión impropia, en tanto que, el sujeto activo/autor tiene incito el nexo de evitación, por lo que, está obligado a evitar que se produzca el resultado lesivo, y permite que se afecte al bien jurídico. Frente a ello, el estudio desarrollado tiene sustento en la tesis de infracción de deber, en la cual el estatus del alto funcionario por su condición especial y personal, no tiene relación directa con el resultado lesivo en el delito de homicidio. En tal sentido,no es posible pretender encajar la tesis del dominio del hecho, por cuanto, no domina ni el riesgo típico que exige un deber específico-deber que el Presidente no defrauda-previsto en una norma extra-penal. De ahí que, se propone la implementación de los criterios jurídicos de: el nexo de evitación, la previsibilidad y el hombre promedio en sociedad; en la postura de garante. Y a fin de operativizar los conceptos propuestos, se concluye que, no es posible atribuir responsabilidad penal al Presidente de la República.The purpose of this research work is to determine legal criteria regarding the position of guarantor held by high-ranking officials, based on the analysis and verification of the status they possess by virtue of their office, as a determining factor in the crime of intentional homicide during social demonstrations. The thesis explores, as a reference, the constitutional complaint No. 150-2020 against former President Merino de Lama as the alleged author of the aforementioned crime. From there, improper omission offenses were studied, considering that the active/author subject has a duty to prevent the harmful outcome and allows the infringement of the legal interest. In light of this, the study is grounded in the theory of breach of duty, in which the status of a high-ranking official, due to their special and personal condition, does not have a direct relationship with the harmful outcome in the crime of homicide. Thus, it's not possible to fit the theory of control of the act, as there is no control over the typical risk that requires a specific duty - a duty that the president does not breach - provided by an extrapenal norm. Therefore, the implementation of the following legal criteria in the position of guarantor is proposed: the duty to prevent, foreseeability, and the average person in society. In order to operationalize the proposed concepts, it is concluded that it is not possible to attribute criminal responsibility to the President of the Republic

    Deep learning methods for enabling real-time gravitational wave and multimessenger astrophysics

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    A new era of gravitational wave (GW) astronomy has begun with the recent detections by LIGO. However, we need real-time observations of GW signals and their electromagnetic (EM) and astro-particle counterparts to unlock its full potential for scientific discoveries. Extracting and classifying the wide range of modeled and unmodeled GWs, whose amplitudes are often much weaker than the background noise, and rapidly inferring accurate parameters of their source is crucial in enabling this scenario of real-time multimessenger astrophysics. Identifying and automatically clustering anomalous non-Gaussian transient noises (glitches) that frequently contaminate the data and separating them from true GW signals is yet another difficult challenge. Currently, the most sensitive data analysis pipelines are limited by the extreme computational costs of template-matching methods and thus are unable to scale to all types of GW sources and their full parameter space. Accurate numerical models of GW signals covering the entire range of parameters including eccentric and spin-precessing compact binaries, which are essential to infer the astrophysical parameters of an event, are not available. Searches for unmodeled and anomalous signals do not have sufficient sensitivity compared to the targeted searches. Furthermore, existing search pipelines are not optimal for dealing with the non-stationary, non-Gaussian noise in the detectors. This indicates that many critical events will go unnoticed. The primary objective of this thesis is to resolve these issues via deep learning, a state-of-the-art machine learning method based on artificial neural networks. In this thesis we develop robust GW analysis algorithms for analyzing real LIGO/Virgo data based on deep learning with neural networks, that overcomes many limitations of existing techniques, allowing real-time detection and parameter estimation modeled GW sources and unmodeled GW bursts as well as classification and unsupervised clustering of anomalies and glitches in the detectors. This pipeline is designed to be highly scalable, therefore it can be trained with template banks of any size to cover the entire parameter-space of eccentric and spin-precessing black hole binaries as well as other sources and also optimized based on the real-time characteristics of the complex noise in the GW detectors. This deep learning framework may also be extended for low-latency analysis of the raw big data collected across multiple observational instruments to further facilitate real-time multimessenger astrophysics, which promises groundbreaking scientific insights about the origin, evolution, and destiny of the universe. In addition, this work introduces a new paradigm to accelerate scientific discovery by using data derived from high-performance physics simulations on supercomputers to train artificial intelligence algorithms that exploit emerging hardware architectures.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2020-12-01The student, Daniel George, accepted the attached license on 2018-12-06 at 00:49.The student, Daniel George, submitted this Dissertation for approval on 2018-12-06 at 01:03.This Dissertation was approved for publication on 2018-12-07 at 07:40.DSpace SAF Submission Ingestion Package generated from Vireo submission #13229 on 2019-02-08 at 11:41:24Made available in DSpace on 2019-02-08T18:44:40Z (GMT). No. of bitstreams: 2 GEORGE-DISSERTATION-2018.pdf: 17941667 bytes, checksum: e0e0c87bdfc2d80f0f05249fe6629633 (MD5) LICENSE.txt: 4210 bytes, checksum: e8bea6db131931d703d8fb97bb52f411 (MD5) Previous issue date: 2018-12-07Embargo set by: Seth Robbins for item 109973 Lift date: 2021-02-08T18:44:50Z Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemLimited Restriction Lifted for Item 109973 on 2021-02-09T10:15:30Z

    Enabling Delay of Gratification Behavior in Those Not So Predisposed: The Moderating Role of Social Support

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    The presence of delay of gratification (DG) in childhood is correlated with success later in a person’s life. Is there any way of helping adults with a low level of DG to obtain similar success? The present research examines how social support helps those low in DG nonetheless to act similarly to those high in DG. This research includes both correlational studies and experiments that manipulate social support as well as both field studies and a laboratory study. The results show that with high social support, employees (Study 1) and university students (Study 2) low in DG report vocational and academic DG behavioral intentions, respectively, similar to those high in DG. Study 3 found that participants low in DG who were primed with high social support expressed job-choice DG similar to those high in the DG. Study 4 controlled for mood and self-image and found that participants low in DG who were primed with high social support expressed more money-choice DG than those high in the DG. Study 5 showed that social support moderated the relationship between DG and actual DG behaviors. These findings provide evidence for a moderating role of social support in the expression of DG behavior

    Structure and function of SLC4 family HCO3– transporters

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    The SLC4 family contains 10 members, nine of which are HCO3– transporters, including three Na+-independent Cl−/HCO3– exchangers AE1, AE2, and AE3, five Na+-coupled HCO3– transporters NBCe1, NBCe2, NBCn1, NBCn2, and NDCBE, as well as AE4 whose Na+-dependence remains controversial. The SLC4 HCO3– transporters play critical roles in pH regulation and transepithelial movement of electrolytes with a broad range of physiological relevances. Dysfunctions of these transporters are associated with a series of human diseases. During the past decades, tremendous amount of efforts have been undertaken to investigate the topological organization of the SLC4 transporters in the plasma membrane. Based upon the proposed topology models, mutational and functional studies have identified important structural elements likely involved in the ion translocation by the SLC4 transporters. In the present article, we will review the advances during the past decades in understanding the structure and function of the SLC4 transporters

    Topography of synchronization of somatosensory evoked potentials elicited by stimulation of the sciatic nerve in rat

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    Purpose: Traditionally, the topography of somatosensory evoked potentials (SEPs) is generated based on amplitude and latency. However, this operation focuses on the physical morphology and field potential-power, so it suffers from difficulties in performing identification in an objective manner. In this study, measurement of the synchronization of SEPs is proposed as a method to explore brain functional networks as well as the plasticity after peripheral nerve injury. Method: SEPs elicited by unilateral sciatic nerve stimulation in twelve adult male Sprague-Dawley (SD) rats in the normal group were compared with SEPs evoked after unilateral sciatic nerve hemisection in four peripheral nerve injured SD rats. The characterization of synchronized networks from SEPs was conducted using equal-time correlation, correlation matrix analysis, and comparison to randomized surrogate data. Eigenvalues of the correlation matrix were used to identify the clusters of functionally synchronized neuronal activity, and the participation index (PI) was calculated to indicate the involvement of each channel in the cluster. The PI value at the knee point of the PI histogram was used as a threshold to demarcate the cortical boundary. Results: Ten out of the twelve normal rats showed only one synchronized brain network. The remaining two normal rats showed one strong and one weak network. In the peripheral nerve injured group, only one synchronized brain network was found in each rat. In the normal group, all network shapes appear regular and the network is largely contained in the posterior cortex. In the injured group, the network shapes appear irregular, the network extends anteriorly and posteriorly, and the network area is significantly larger. There are considerable individual variations in the shape and location of the network after peripheral nerve injury. Conclusion: The proposed method can detect functional brain networks. Compared to the results of the traditional SEP-morphology-based analysis method, the synchronized functional network area is much larger. Furthermore, the proposed method can also characterize the rapid cortical plasticity after a peripheral nerve is acutely injured

    Temporal and spatial dynamics of archaeal communities in two freshwater lakes at different trophic status

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    In either eutrophic Dianchi Lake or mesotrophic Erhai Lake, the abundance, diversity and structure of archaeaplankton communities in spring were different from those in summer. In summer, archaeaplankton abundance generally decreased in Dianchi Lake but increased in Erhai Lake, while archaeaplankton diversity increased in both lakes. These two lakes had distinct archaeaplankton community structure. Archaeaplankton abundance was influenced by organic content, while trophic status determined archaeaplankton diversity and structure. Moreover, in summer, lake sediment archaeal abundance considerably decreased. Sediment archaeal abundance showed a remarkable spatial change in spring but only a slight one in summer. The evident spatial change of sediment archaeal diversity occurred in both seasons. In Dianchi Lake, sediment archaeal community structure in summer was remarkably different from that in spring. Compared to Erhai Lake, Dianchi Lake had relatively high sediment archaeal abundance but low diversity. These two lakes differed remarkably in sediment archaeal community structure. Trophic status determined sediment archaeal abundance, diversity and structure. Archaeal diversity in sediment was much higher than that in water. Water and sediment habitats differed greatly in archaeal community structure. Euryarchaeota predominated in water column, but showed much lower proportion in sediment. Bathyarchaeota was an important component of sediment archaeal community

    Discrimination of Fearful and Angry Emotional Voices in Sleeping Human Neonates: a Study of the Mismatch Brain Responses

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    Appropriate processing of human voices with different threat-related emotions is of evolutionarily adaptive value for the survival of individuals. Nevertheless, it is still not clear whether the sensitivity to threat-related information is present at birth. Using an oddball paradigm, the current study investigated the neural correlates underlying automatic processing of emotional voices of fear and anger in sleeping neonates. Event-related potential data showed that the frontocentral scalp distribution of the neonatal brain could discriminate fearful voices from angry voices; the mismatch response (MMR) was larger in response to the deviant stimuli of anger, compared with the standard stimuli of fear. Furthermore, this fear-anger MMR discrimination was observed only when neonates were in active sleep state. Although the neonates’ sensitivity to threat-related voices is not likely associated with a conceptual understanding of fearful and angry emotions, this special discrimination in early life may provide a foundation for later emotion and social cognition development
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