1,047 research outputs found

    Parasitic copepods from Egyptian Red Sea fishes: Bomolochidae Claus, 1875

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    © The Author(s) 2015 Open Access - This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The attached file is the published version of the article.NHM Repositor

    Semantic model-driven development of web service architectures.

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    Building service-based architectures has become a major area of interest since the advent of Web services. Modelling these architectures is a central activity. Model-driven development is a recent approach to developing software systems based on the idea of making models the central artefacts for design representation, analysis, and code generation. We propose an ontology-based engineering methodology for semantic model-driven composition and transformation of Web service architectures. Ontology technology as a logic-based knowledge representation and reasoning framework can provide answers to the needs of sharable and reusable semantic models and descriptions needed for service engineering. Based on modelling, composition and code generation techniques for service architectures, our approach provides a methodological framework for ontology-based semantic service architecture

    Surfactant protein D deficiency aggravates cigarette smoke-induced lung inflammation

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    Cigarette smoke (CS) is a main cause of chronic obstructive pulmonary disease. Surfactant protein D (SP-D) regulates host immune defence in the lungs. We investigated the role of SP-D in a murine model of CS-induced pulmonary inflammation.Wild type and SP-D-deficient mice were exposed to CS for 12 weeks or 3 days. Cell counts and inflammatory cytokine levels in bronchoalveolar lavage fluid were determined. Changes in lipid content were assessed by mass spectrometry. Moreover, the effect of therapeutic administration of recombinant fragment of human SP-D on the acute CS-induced changes was investigated.In humans, SP-D was upregulated in the lungs of smokers. Moreover, we found that SP-D-deficient mice were more susceptible to CS-induced macrophage-rich airway inflammation. SP-D deficiency influenced local levels of inflammatory cytokines, with increased CCL3 and interleukin-6 but decreased CXCL1. While overall lipid content was higher in SP-D-deficient mice compared to wild type littermates, CS exposure caused significant upregulation of pro-inflammatory ceramides and related ceramide synthase genes in SP-D-deficient mice. Finally, administration of recombinant SP-D alleviated CS-induced macrophage infiltration.Our results indicate that SP-D deficiency aggravates CS-induced lung inflammation and that recombinant SP-D is a potential therapeutic option for anti-inflammatory treatment of CS-induced pulmonary pathology.<br/

    Meningsdannelser og paradokser i det interne og tværfaglige samarbejde: Et casestudie af en "anderledes" folkeskole

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    This thesis is a qualitative case study on the sensemaking processes and paradoxes that exist in the teachers' internal collaboration and interdisciplinary cooperation with other professions, in social and special educational work. The visions and ideas for the future of an inclusive school policy contains a major transformation in the cooperation between a school's professional stakeholders. This cooperation is crititical if a school is to successfully meet the policy objectives of merging special geographical areas with a general catchment area, so that all children, regardless of their socail conditions, can be included in the future of schooling.The existing research on schooling, indicates general difficulties between a schools professional stakeholders, which is why the political thought is towards teacher collaboration, closer teaching groups and an increased focus on the interdisciplinary cooperation between groups such as PPR and schools. The Copenhagen has, for the school year 2012-13, decided to establish resource centers in all the local schools in order to give a more unified, holistic and systematic approach together with"a common language". The aim is to provide schools with the necessary competences to solve the social and special educational challenges that lie ahead. With our experience from elementary school, we are primarily concerned with the political and scientific attention given to mainly quantitative goals whilst evaluating schools and the school's own practice. It is for this reason, whilst studying for a Masters in Social work, that we have found it necessary to examine the interaction and cooperation processes taking place at a school that is built on political ideals. The school which provides the framework for the thesis case, is characterized as an extreme and paradigmatic case. The school, since its beginning as an experimental school in 1973, is characterized by close teamwork and many years of experience of working together alongside a competence center. In other words, the schools' experience in internal and interdisciplinary cooperation can be utilized as a source of knowledge and insight into the opinion formation and paradoxes that may arise in the relationship between various professions.Through Karl. E. Weick's theory of Sensemaking in Organization and Ralph. D. Stacey theory of "Complex responsive processes" we investigate through social constructivist methods, how a large school creates stability and change in the communicative cooperation processes that exist between school professionals, teachers and ressource persons. We go through the identification of several organizational issues which can be both valid or invalid or even opinion based. We go through qualitative interviews and observations, thus obtaining new insights and knowledge into the difficulties a school will be presented with on a daily basis. In particular, the systemic approach to the social work, combined with a lack of participation and communication between the stakeholders in the school's own themes, creates problems for cooperation, both internally and between the various disciplines. This may well prove to have consequences, not only for the professionals, but also for the student or the entire class<br/

    Spilleregler i det journalistiske interview - praktiske redskaber og psykologiske virkemidler

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    #En analyse af et debatinterview fra DR2 Deadline d. 29/10 2005. Debatten stod mellem beskæftigelsesministeren Claus Hjort Frederiksen og cand.jur. Safia Aoude, dette på baggrund af en kronik hvor Safia Aoude anklager de borgerlige politikere for at være for islamofobiske. Interviewer var journalist Nynne Bjerre Christensen. Vi påviser i vores rapport, hvorledes journalisten og/eller interviewpersoner kan benytte sig af praktiske journalistiske redskaber og psykologiske virkemidler i en interviewsituattion. I vores analyse påpeger vi, at Nynne Bjerre Christensen ikke formåede at gøre fuldt brug af disse, endvidere konkluderede vi at Claus Hjort Frederiksen, som medievandt interviewperson, formåede at vende interviewsituationen til egen fordel. Vi vurderer desuden, at journalistens subjektivitet kan valideres, hvis denne samtidig holder et højt informationsniveau overfor modtager.#En analyse af et debatinterview fra DR2 Deadline d. 29/10 2005. Debatten stod mellem beskæftigelsesministeren Claus Hjort Frederiksen og cand.jur. Safia Aoude, dette på baggrund af en kronik hvor Safia Aoude anklager de borgerlige politikere for at være for islamofobiske. Interviewer var journalist Nynne Bjerre Christensen. Vi påviser i vores rapport, hvorledes journalisten og/eller interviewpersoner kan benytte sig af praktiske journalistiske redskaber og psykologiske virkemidler i en interviewsituattion. I vores analyse påpeger vi, at Nynne Bjerre Christensen ikke formåede at gøre fuldt brug af disse, endvidere konkluderede vi at Claus Hjort Frederiksen, som medievandt interviewperson, formåede at vende interviewsituationen til egen fordel. Vi vurderer desuden, at journalistens subjektivitet kan valideres, hvis denne samtidig holder et højt informationsniveau overfor modtager

    Fra sygdomsforfald til sygefravær – arbejde og sygdom mellem rettigheder og pligter i den moderne velfærdsstat

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    Denne artikel forsøger at belyse forholdet mellem arbejde og helbred, ved at analysere sygefravær og midlertidig uarbejdsdygtighed i et historisk lys fra 1950’erne og frem til i dag. I analysen gøres der brug af et forskelligartet historisk materiale taget fra danske dagblade, tidsskrifter og politiske debatter. Artiklen viser, at sygefravær kan forstås som et fundamentalt ambivalent fænomen, der på den ene side indebærer frigørelse for arbejderne, som får mulighed for midlertidigt at være uarbejdsdygtige uden alt for store økonomiske kvaler. På den anden side indebærer disse nyvundne rettigheder også, at danske virksomheder og lovgivningen udvikler nye måder at styre medarbejderne på. Resultatet er blandt andet at de mest svagelige arbejdere skubbes helt ud af arbejdsmarkedet. Men samtidig bliver også medarbejdere uden store helbredsproblemer udsat for en ’normaliseringsproces’, hvor statistikker om sygefraværets niveau og samtaler om sygefraværs bruges som styringsteknologier for at regulere medarbejderne. Det er dog også muligt at se disse ’styringsteknologier’, som processer, der igangsætter en rationalisering af dele af livsverdenen, som ellers havde været præget af dogmer og uhensigtsmæssige måder at koordinere handling på

    The impact of economic inequalities on self-esteem and depression.:A longitudinal study from Denmark

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    Background: During the last five years, negative consequences of austerity politics (e.g. its impact on soft outcomes such as self-esteem and mental health) have been dismissed as being irrelevant as arguments against ‘necessary’ social reforms and cut backs in many European countries including Denmark. But how important are economic factors, e.g. childhood experiences of parental unemployment, poverty and difficulties participating in leisure time activities as antecedents for self-esteem and depression?Methods: Information from a birth cohort study of all adolescents born in 1989 (n=3,058) living in Ringkøbing County, Denmark in 2004 was collected across three questionnaire rounds (age 15, 18 and 21) containing questions about self-esteem (Rosenberg scale), symptoms of depression and many other , health, peer relations, school etc. Information on social background of the participants (e.g. personal income, parental income and education etc.) was derived from a national register and linked to the data. Random and fixed effects regression was used to estimate the impact of economic deprivation on self-esteem and depression.Results: In general, self-esteem increases across the three questionnaire rounds, i.e. as the adolescents grow from age 15 to 21. There are, however, marked differences in the growth rate across adolescents with different levels of parental income: adolescents from the richest tertile grow 1.14 points on the scale whereas adolescents from the poorest tertile grow 0.88 points. Experiences of being unable to afford participating in leisure time activities that cost money or going on trips lowered self-esteem by 0.4. Finally, the fixed effects regression shows big differences in self-esteem comparing adolescents with different levels of personal income: being in the highest quartile increases self-esteem by 1.75 (95% CI: 1.22-2.28) compared to those in the lowest quartile. Similar results were found for symptoms of depression as outcome.Conclusion: Self-esteem and symptoms of depression among adolescents are affected by experiences of economic hardship. This is important to keep in mind when discussing the consequences of social reforms and austerity politics across many European countries. <br/
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