55 research outputs found
Experience with using of HHC by fourth class students of secondary school: questionaire survey
No full textBackground: Hexahydrocannabinol (HHC) is a polysynthetic cannabinoid that was introduced to the Czech Republic in May 2022, making it a recent addition to the cannabis product market. Products containing HHC quickly became highly attractive to the younger generation and were widely sold across all age groups before their temporary ban. Objectives: The primary objective of this study was to map the experiences of HHC use among fourth-year high school students in the Svitavy district of the Pardubice region. The study aimed to determine whether students use the substance, the frequency of use, the form in which it is consumed, and where they obtain it. Another objective was to explore any correlation between the use of HHC and THC among the same respondents. Methods: Given the topic and objectives of this study, a quantitative research approach was chosen. Data collection was conducted through an anonymous online questionnaire using Google Forms. Five high schools in the Svitavy district were contacted, granting the author access to fourth-year classes where the research was carried out. The schools included grammar/high schools and vocational schools. Data collection occurred in February 2024, with students completing the questionnaire on their smart devices. The collected data were analyzed using..
Experience with using of HHC by fourth class students of secondary school: questionaire survey
No full textVýchodiska: Hexahydrokanabinol (HHC) je polysyntetický kanabinoid, který se do České republiky dostal v květnu roku 2022. Je proto žhavou novinkou na trhu s konopnými produkty. Produkty obsahující HHC byly velice atraktivní pro mladou generaci a před jeho dočasným zákazem byly hojně prodejné pro všechny věkové kategorie. Cíle: Hlavním cílem této práce bylo zmapovat zkušenosti s užíváním HHC u studentů čtvrtých ročníků středních škol v okrese Svitavy v Pardubickém kraji. Šlo o zjištění, zda studenti látku užívají, popřípadě jak často, v jaké formě a kde si látku obstarávají. Dalším cílem výzkumu bylo zjistit, zda existuje souvislost mezi užitím HHC a THC u týchž respondentů. Metody: S ohledem na téma práce a její cíle, byl pro výzkum zvolen kvantitativní výzkum. Ke sběru dat byl jako výzkumný nástroj zvolen anonymní online dotazník na platformě Google formuláře. Pro výzkum bylo osloveno 5 středních škol v okrese Svitavy, které poskytly autorce přístup do tříd 4. ročníků, kde byl výzkum realizován. Jednalo se o gymnázia/lycea a střední odborné školy. Sběr dat probíhal v průběhu února 2024. Studenti vyplňovali dotazník na svých chytrých zařízeních. Získaná data byla zpracována popisnou statistikou a vložena do práce v podobě tabulek a grafů. Výsledky: Celého výzkumu se zúčastnilo 193 respondentů. Z...Background: Hexahydrocannabinol (HHC) is a polysynthetic cannabinoid that was introduced to the Czech Republic in May 2022, making it a recent addition to the cannabis product market. Products containing HHC quickly became highly attractive to the younger generation and were widely sold across all age groups before their temporary ban. Objectives: The primary objective of this study was to map the experiences of HHC use among fourth-year high school students in the Svitavy district of the Pardubice region. The study aimed to determine whether students use the substance, the frequency of use, the form in which it is consumed, and where they obtain it. Another objective was to explore any correlation between the use of HHC and THC among the same respondents. Methods: Given the topic and objectives of this study, a quantitative research approach was chosen. Data collection was conducted through an anonymous online questionnaire using Google Forms. Five high schools in the Svitavy district were contacted, granting the author access to fourth-year classes where the research was carried out. The schools included grammar/high schools and vocational schools. Data collection occurred in February 2024, with students completing the questionnaire on their smart devices. The collected data were analyzed using...Department of Addictology First Faculty of Medicine Charles University and General University Hospital in PragueKlinika adiktologie 1. LF UK a VFN1. lékařská fakultaFirst Faculty of Medicin
Hillclimbing in a hierarchy of abstraction spaces
No full textHillclimbing search has been shown to be useful for solving constraint satisfaction problems that are too large to be attacked using backtracking search. Nevertheless, hillclimbing search can be computationally expensive when the length of each climb is long, or when many climbs are required due to the presence of local, but non-global optima. ``Hierarchic Hillclimbing'' (HHC) is an extension of ordinary ``Flat Hillclimbing'' that is designed to attack such difficulties. HHC carries out hillclimbing search in a hierarchy of abstraction spaces, starting with the most abstract and proceeding to the most concrete. HHC takes as input a description of the abstraction hierarchy, as well as an evaluation function for each abstraction level. The HHC algorithm has been implemented along with a program to synthesize the required abstraction hierarchies and evaluation functions. The synthesis program and the HHC algorithm have been tested in the domains of uniprocessor scheduling and two dimensional tile packing. Results show HHC to improve in two ways on ordinary hillclimbing without abstraction: HHC requires less computation time to complete a single climb. In addition, when the abstraction hierarchy is chosen with care HHC is more likely to find a solution on a single climb.Technical report LCSR-TR-19
Electrochemical determination of hydrogen peroxide using Rhodobacter capsulatus cytochrome c peroxidase at a gold electrode
No full textWe describe the redox behaviour of horse heart cytochrome c (HHC) and Rhodobacter capsulatus cytochrome c peroxidase (RcCCP) at a gold electrode modified with 4,4?-bipyridyl. RcCCP shows no additional oxidation or reduction peaks compared to the electrochemistry of only HHC, which indicates that it most likely binds to HHC and results in a potential downshift of the voltammetric signals of the latter. Furthermore, the electrochemical determination of hydrogen peroxide at a RcCCP/HHC modified gold electrode is shown. The results demonstrate that HHC can substitute for cytochrome c 2, the physiological electron donor. The buffer 2-[4-(2-hydroxyethyl)-piperazinyl]?ethanesulfonic acid (HEPES) and tris(hydroxymethyl) methylamine (Tris) electrochemically are not as inert as previously believed. They can react with oxygen (radicals) during electrochemical measurements, and the products formed can give rise to additional redox peaks. We therefore also have conducted a voltammetric study on theses buffers.Kavli Institute of NanoscienceApplied Science
A Novel Concept for Home Healthcare Operations Using Electric Home Delivery Vehicles
No full textHealthcare systems worldwide rely heavily on the efficient allocation of caregivers in home- based care. Despite this, to this day, the majority of home healthcare (HHC) organisations plan their operations manually, an extremely time-consuming and labour-intensive task yielding sub-optimal solutions. Research efforts in the operations research (OR) field have extensively studied said problem under the HHC routing and scheduling problem (HHCRSP). However, the separate consideration of the planning of caregivers and re- sources required at visits are considered a relevant gap in the literature, as real-world organisations must plan both simultaneously.As a solution toward bridging this gap, this paper proposes the introduction of home de- livery vehicles (HDVs) to support HHC operations, in which the vehicles deliver resources required at patient visits in time for consultation. A mathematical formulation consider- ing the routing, scheduling, and synchronisation of caregivers and vehicles is presented, in which partial battery charging alongside hard visit and working time windows are key characteristics. A genetic algorithm (GA) is further developed to solve the proposed for- mulation, which is proven to perform efficiently in benchmark instances for the vehicle routing problem (VRP). Simulations were run on data generated synthetically by a sta- tistical model recreating the HHC needs of the London Borough of Islington. The results highlight the potential benefits of adopting such technology, resulting in an average re- duction of the required medical resources of 49.94% and a 19.23% reduction in costs with respect to standard operations using the same number of resources.Overall, the most economical operating strategy for a HHC organisation was identified to be the purchase of a number of resources equal to the number of visits requiring said re- sources. Such an approach was found to decrease the costs per visit by 1.26% with respect to HDVs. The marginal amount, however, is expected to be diminished in the coming years due to factors not captured in the analysis such as the higher scalability of HDVs and their resulting potential to meet the anticipated growth in demand for HHC, the ex- pected decrease in the price of electric vehicle technology, the economic incentives offered to adopt said technologies, and the potential collaboration between caregivers and HDVs. These, alongside extensions to the proposed model such as non-linear battery charging, are proposed as future research avenues.Mechanical Engineering | Multi-Machine Engineerin
Bifurcation behavior in parallel-connected buck converters
No full textAuthor name used in this publication: H. H. C. IuAuthor name used in this publication: C. K. Tse2000-2001 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishedVoR allowe
Establishing Guidelines for Implementing Electronic Hand Hygiene Monitoring Systems
No full textHealthcare-associated infections (HAIs) in hospitals threaten patient safety and quality of care, which leads to increased healthcare costs. Despite national and state-level progress in hand hygiene compliance (HHC), the 2022 CDC annual report on HAIs highlighted ongoing concerns for standard infection ratios (SIRs) and called for improved HHC to reduce HAIs. Many hospitals use trained observers to collate HHC data; their audits are limited and often skewed by the Hawthorne Effect (HE) and observer bias, resulting in inaccurate HHC data. This project aimed to create guidelines for implementing electronic hand hygiene monitoring systems (EHHMSs) to help hospital inpatient units adopt EHHMSs.
The author conducted a literature search in the Cumulative Index of Nursing and Allied Health Literature (CINAHL), Trip Medical Database, and the Agency for Healthcare Research and Quality (AHRQ) and found no guidelines for implementing EHHMSs. The author systematically reviewed the literature on EHHMSs and gathered stakeholders\u27 recommendations through a 5-point Likert scale survey. The literature review and stakeholder feedback indicated that EHHMSs could significantly improve HHC and reduce HAIs. Implementing EHHMSs in hospital inpatient units could enhance HHC, reduce HAIs, and improve patient safety. The guidelines provided a framework for hospitals to adopt EHHMSs effectively
A study of synchronization in chaotic autonomous Ćuk dc/dc converters
No full textAuthor name used in this publication: H. H. C. IuAuthor name used in this publication: C. K. TseVersion of RecordPublishedVoR allowe
Study of low-frequency bifurcation phenomena of a parallel-connected boost converter system via simple averaged models
No full textAuthor name used in this publication: H. H. C. IuAuthor name used in this publication: C. K. Tse2002-2003 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishedVoR allowe
Bifurcation in parallel-connected buck converters under a democratic current sharing scheme
No full textAuthor name used in this publication: H. H. C. IuAuthor name used in this publication: C. K. TseInvited conference paper2000-2001 > Academic research: refereed > Invited conference paperVersion of RecordPublishedVoR allowe
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