4,236 research outputs found

    Comparison of the toxicokinetics of daidzein and bisphenol A in pregnant and non-pregnant DA/Han rats

    Get PDF
    Potentially adverse human and environmental effects due to hormone mimicry of environmental estrogens are a matter of current concern. Environmental estrogens belong to the socalled endocrine active compounds (EAC) and may alter signalling processes of the endocrine system leading to a broad range of effects during fetal and postnatal development, puberty, adulthood, and aging. A number of synthetic chemicals as well as several plant-derived compounds, socalled phytoestrogens, are known to have weak estrogenic activity. The present study is part of the risk assessment of the weak environmental estrogens daidzein and bisphenol A. The isoflavone daidzein is an important phytoestrogen with respect to dietary exposure (soy beans and soy products) whereas bisphenol A is an industrial chemical that occurs at much lower concentrations as a contaminant in food. The toxicokinetics of these compounds in female pregnant and non-pregnant DA/Han rats after single intravenous application were compared by the use of the Mann-Whitney- U-statistic. --Bisphenol A,daidzein,xenoestrogens,phytoestrogens,endocrine active compounds,Mann-Whitney-U-test

    New (Probabilistic) Derivation of Diaz-Metcalf and Pólya-Szegő Inequalities and Consequences

    No full text
    Classical inequalities of Diaz - Metcalf and Pólya - Szegő are generalized to probabilistic setting which covers the initial deterministic (both discrete and integral) variants. From these two inequalities, by the probabilistic derivation method further well - known inequalities are obtained (that ones by Kantorovich, Rennie and Schweitzer)

    Mouvance and the medieval author: re-editing Ancrene Wisse

    No full text
    The paper discusses the theoretical and practical problems of editing the early thirteenth-century guide for anchoresses, Ancrene Wisse, which (in Paul Zumthor's phrase) is an 'oeuvre mouvante', modified repeatedly from an early stage by its author and others

    D.S. Merezhkovsky and C.G. Jung: General and Special

    No full text
    В статье рассмотрены особенности трактовки символа в творчестве Д.С. Мережковского и К.Г. Юнга. Показано влияние идей Мережковского на формирование воззрений К.Г. Юнга, проведен сопоставительный анализ их концепций символа как многозначной и универсальной категории, подчеркнуто значение творчества мыслителей для интерпретации исторических событий и осмысления современной общественной ситуации.The article describes the features of the interpretation of the symbol in the works of D.S. Merezhkovsky and K.G. Jung. The author focuses the attention on the influence Merezhkovsky's ideas on the formation of views of Jung, conducted a comparative analysis their conceptions of symbolism as a multi–valued and universal category, stressed the importance thinkers’ works for the interpret historical events and understanding the contemporary social situation
    corecore