1,721,627 research outputs found

    Nanoscale hybrid coating enables multifunctional tissue scaffold for potential multimodal therapeutic applications

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    Through a nature-inspired layer-by-layer assembly process, we developed a unique multifunctional tissue scaffold that consists of porous polyurethane substrate and nanoscale chitosan/graphene oxide hybrid coating. Alternative layers of drug-laden chitosan and graphene oxide nanosheets were held together through strong electrostatic interaction, giving rise to a robust multilayer architecture with control over structural element orientation and chemical composition at nanoscale. Combined pH-controlled co-delivery of multiple therapeutic agents and photothermal therapy has been achieved by our scaffold system. The new platform technology can be generalized to produce other tissue scaffold systems and may enable potential multimodal therapeutic applications such as bone cancer managements

    Hamilton, Andrew, Engineering Draftsman At Ipoh

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    This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/389960Surname: HAMILTON. Given Name(s) or Initials: ANDREW. Military Service Number or Last Known Location: ENGINEERING DRAFTSMAN AT IPOH. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 58079.214667 Item: [2016.0049.22253] "Hamilton, Andrew, Engineering Draftsman At Ipoh

    Improving traffic movement in an urban environment

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    This research seeks to investigate how additional data sources can be used within traffic control systems to reduce average delay and improve reliability of journey time. Current state of the art urban traffic control systems do not take full advantage of the improved granularity of data available as they use traditional, static detection methods such as inductive loops, infra-red and radar.Therefore further research was required to fully understand what new data sources are available, how they could be used and if there are any potential benefits for traffic control systems. The transport industry is moving into an era of data abundance as more people use smart phones, satellite navigation systems, Wi-Fi and Bluetooth devices. These richer data sources could provide additional information (vehicle location, speed and destination data) but it is currently unknown as to whether they can improve the performance of the road network.Much of the research in this thesis has been published through conference and journal papers. A novel traffic control algorithm called DEMA was developed during this research, which can significantly outperform MOVA (a leading industrial control algorithm) through reducing average delay by up to 34% when additional data sources are incorporated into the decision process. DEMA uses vehicle location, speed and turning intention information to select the most suitable stage for minimising delay.Also a study was conducted to determine if turning intention information could be predicted from outside of a vehicle, which is a previously un-researched area. The results demonstrated that people could correctly predict turning intention with a 70% median success rate when the vehicles were 50 metres from the junction.The outcomes of this research could have a significant impact on the future of urban traffic control systems as new data sources become more readily available in the transport industry

    Dataset to support the Southampton Doctoral thesis 'Emissivity and resistivity of SLM 316L stainless steel'

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    This data is the total hemispherical emissivity and resistivity for 316L stainless steel manufactured by SLM. The data was collected on 17 different samples, each manufactured using different combinations of SLM process parameters (build angle, laser power, scanning speed, hatch spacing and layer thickness). Details of the process parameters are in the PhD thesis. This dataset contains: Total hemispherical emissivity and resistivity data for 316L stainless steel 17 different samples. </span

    Canons and the test of time and place

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    At the time of writing, Lubaina Himid has an exhibition at Tate Modern. A British artist of Afro-Caribbean heritage, and key figure in the British Black arts scene since the 1980s, she is internationally recognised for her figurative paintings, which explore neglected aspects of history and of everyday life. At the same time as Himid's exhibition, the Hayward Gallery's exhibition In the Black Fantastic features eleven contemporary artists from the African diaspora. Canons, it seems, are opening up. Himid's work is sometimes humorous, often self-deprecating; she belongs to the generation of British artists of Afro-Caribbean origin, including Frank Bowling and Chris Ofili. She won the Turner Prize in 2017, and received a CBE following year for contributions to the arts. However, until the last decade her work was neglected. Her biography shows the vital importance of mechanisms of inclusion in artistic canons

    Amphiphilic a-helix mimetics based on a benzoylurea scaffold

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    The design and synthesis of amphiphilic benzoylurea ?-helix mimetics is described. These conformationally constrained molecules allow for the correct angular and spatial projection of hydrophobic and hydrophilic groups and thus the reproduction of side-chains on both faces of an ?-helix

    FIGURES 3–4 in Revision of Neotropical aphrophorine spittlebugs, part 1: Ptyelini (Hemiptera, Cercopoidea)

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    FIGURES 3–4. Morphology of head (3) and wings (4) of Ptyelini. 3A. face of Cephisus sanguisuga, holotype; 3B. head and pronotum, ventrolateral aspect, of C. xanthocephala, holotype; 3C. head and propleuron of unidentified Cercopinae; 4A. tegmen of C. siccifolia, ventral aspect showing ventral flange ("Sc" of authors); 4B. hindwing of same; 4C. same, of Ptyelus sp.; 4D. same, of Eulepyronia grossa Schmidt, holotype.Published as part of Hamilton, Andrew, 2012, Revision of Neotropical aphrophorine spittlebugs, part 1: Ptyelini (Hemiptera, Cercopoidea), pp. 41-59 in Zootaxa 3497 on page 45, DOI: 10.5281/zenodo.28246

    An alpha-helical peptidomimetic scaffold for dynamic combinatorial library formation

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    A novel oligobenzamide-based alpha-helix mimetic was designed and synthesised with either imine or hydrazone functionalities that serve both to pre-organise the side-chain vectors to mimic the i, i + 4 and i + 7 residues of an alpha-helix, and to allow for the facile creation of dynamic libraries

    Forecasting road traffic conditions using a context based random forest algorithm

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    With the ability to accurately forecast road traffic conditions several hours, days and even months ahead of time, both travellers and network managers can take pro-active measures to minimize congestion, saving time, money and emissions. This study evaluates a previously developed random forest algorithm, RoadCast, which was designed to achieve this task. RoadCast incorporates contexts using machine learning to forecast more accurately, contexts such as public holidays, sporting events and school term dates. This study aims to evaluate the potential of RoadCast as a traffic forecasting algorithm for use in Intelligent Transport Systems applications. Tests are undertaken using a number of different forecast horizons and varying amounts of training data, and an implementation procedure is recommended
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