12 research outputs found
Chronic mild hypoxia accelerates recovery from pre-existing EAE by enhancing vascular integrity and apoptosis of infiltrated monocytes.
No full textThese files contains the data sets for the study described in the title.</p
Absence of endothelial α5β1 integrin triggers early onset of experimental autoimmune encephalomyelitis due to reduced vascular remodeling and compromised vascular integrity
No full textAbstract Early in the development of multiple sclerosis (MS) and its mouse model experimental autoimmune encephalomyelitis (EAE), vascular integrity is compromised. This is accompanied by a marked vascular remodeling response, though it is currently unclear whether this is an adaptive vascular repair mechanism or is part of the pathogenic process. In light of the well-described angiogenic role for the α5β1 integrin, the goal of this study was to evaluate how genetic deletion of endothelial α5 integrin (α5-EC-KO mice) impacts vascular remodeling and repair following vascular disruption during EAE pathogenesis, and how this subsequently influences clinical progression and inflammatory demyelination. Immunofluorescence staining revealed that fibronectin and α5 integrin expression were strongly upregulated on spinal cord blood vessels during the pre-symptomatic phase of EAE. Interestingly, α5-EC-KO mice showed much earlier onset and faster progression of EAE, though peak disease severity and chronic disease activity were no different from wild-type mice. At the histological level, earlier disease onset in α5-EC-KO mice correlated with accelerated vascular disruption and increased leukocyte infiltration into the spinal cord. Significantly, spinal cord blood vessels in α5-EC-KO mice showed attenuated endothelial proliferation during the pre-symptomatic phase of EAE which resulted in reduced vascular density at later time-points. Under pro-inflammatory conditions, primary cultures of α5KO brain endothelial cells showed reduced proliferation potential. These findings suggest that α5β1 integrin-mediated angiogenic remodeling represents an important repair mechanism that counteracts vascular disruption during the early stages of EAE development
Spinal Cord Blood Vessels in Aged Mice Show Greater Levels of Hypoxia-Induced Vascular Disruption and Microglial Activation
No full textIn response to chronic mild hypoxia (CMH, 8% O2), spinal cord blood vessels launch a robust angiogenic response that is associated with transient disruption of the blood–spinal cord barrier (BSCB) which, in turn, triggers a microglial vasculo-protective response. Because hypoxia occurs in many age-related conditions, the goal of this study was to define how aging influences these responses by comparing events in young (8–10 weeks) and aged (20 months) mice. This revealed that aged mice had much greater (3–4-fold) levels of hypoxic-induced BSCB disruption than young mice and that, while the early stage of the angiogenic response in aged mice was no different to young mice, the maturation of newly formed vessels was significantly delayed. Interestingly, microglia in the spinal cords of aged mice were much more activated than young mice, even under normoxic conditions, and this was further enhanced by CMH, though, surprisingly, this resulted in reduced microglial clustering around leaky blood vessels and diminished vasculo-protection. Vascular disruption was associated with loss of myelin in spinal cord white matter (WM) in both young and aged mice. Furthermore, it was notable that the spinal cord of aged mice contained a lower density of Olig2+ oligodendroglial cells even under normoxic conditions and that CMH significantly reduced the density of Olig2+ cells in spinal cord WM of the aged, but not the young, mice. These results demonstrate that spinal cord blood vessels of aged mice are much more vulnerable to the damaging effects of hypoxia than young mice, in part due to the reduced vasculo-protection conferred by chronically activated microglial cells. These observations may have implications for the pathogenesis and/or treatment of spinal cord diseases such as amyotrophic lateral sclerosis (ALS) and suggest that an improvement in microglial function could offer therapeutic potential for treating these age-related conditions
Chronic mild hypoxia promotes profound vascular remodeling in spinal cord blood vessels, preferentially in white matter, via an α5β1 integrin-mediated mechanism
No full textHypoxic pre-conditioning suppresses experimental autoimmune encephalomyelitis by modifying multiple properties of blood vessels
No full textAbstract While hypoxic pre-conditioning protects against neurological disease the underlying mechanisms have yet to be fully defined. As chronic mild hypoxia (CMH, 10% O2) triggers profound vascular remodeling in the central nervous system (CNS), the goal of this study was to examine the protective potential of hypoxic pre-conditioning in the experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS) and then determine how CMH influences vascular integrity and the underlying cellular and molecular mechanisms during EAE. We found that mice exposed to CMH at the same time as EAE induction were strongly protected against the development of EAE progression, as assessed both at the clinical level and at the histopathological level by reduced levels of inflammatory leukocyte infiltration, vascular breakdown and demyelination. Mechanistically, our studies indicate that CMH protects, at least in part, by enhancing several properties of blood vessels that contribute to vascular integrity, including reduced expression of the endothelial activation molecules VCAM-1 and ICAM-1, maintained expression of endothelial tight junction proteins ZO-1 and occludin, and upregulated expression of the leukocyte inhibitory protein laminin-111 in the vascular basement membrane. Taken together, these data suggest that optimization of BBB integrity is an important mechanism underlying the protective effect of hypoxic pre-conditioning
Endothelial α6β4 integrin protects during experimental autoimmune encephalomyelitis-induced neuroinflammation by maintaining vascular integrity and tight junction protein expression
No full textAbstract Background Extracellular matrix (ECM) proteins play critical functions regulating vascular formation and function. Laminin is a major component of the vascular basal lamina, and transgenic mice deficient in astrocyte or pericyte laminin show defective blood-brain barrier (BBB) integrity, indicating an important instructive role for laminin in cerebral blood vessels. As previous work shows that in the normal brain, vascular expression of the laminin receptor α6β4 integrin is predominantly restricted to arterioles, but induced on all vessels during neuroinflammation, it is important to define the role of this integrin in the maintenance of BBB integrity. Methods α6β4 integrin expression was analyzed using dual immunofluorescence (dual-IF) of brain sections taken from the mouse model of multiple sclerosis, experimental autoimmune encephalomyelitis (EAE). To investigate the role of endothelial α6β4 integrin, transgenic mice lacking β4 integrin in endothelial cells (β4-EC-KO) and wild-type (WT) littermates were subject to EAE, and clinical score and various neuropathological parameters were examined by immunofluorescence. In addition, β4 integrin null brain endothelial cells (BECs) were examined in culture for expression of tight junction proteins using immunocytochemistry and flow cytometry. Results Cerebrovascular expression of β4 integrin was markedly upregulated during EAE progression, such that by the acute stage of EAE (day 21), the vast majority of blood vessels expressed β4 integrin. In the EAE model, while the β4-EC-KO mice showed the same time of disease onset as the WT littermates, they developed significantly worse clinical disease over time, resulting in increased clinical score at the peak of disease and maintained elevated thereafter. Consistent with this, the β4-EC-KO mice showed enhanced levels of leukocyte infiltration and BBB breakdown and also displayed increased loss of the endothelial tight junction proteins claudin-5 and ZO-1. Under pro-inflammatory conditions, primary cultures of β4KO BECs also showed increased loss of claudin-5 and ZO-1 expression. Conclusions Taken together, our data suggest that α6β4 integrin upregulation is an inducible protective mechanism that stabilizes the BBB during neuroinflammatory conditions
Endothelial α6β4 integrin protects during experimental autoimmune encephalomyelitis-induced neuroinflammation by maintaining vascular integrity and tight junction protein expression
No full textPartial eNOS Deficiency Results in Greater Levels of Vascular Inflammation and BBB Disruption in Response to Chronic Mild Hypoxia
No full textBlood–brain barrier (BBB) deterioration with increasing age is an important factor contributing to vascular dementia. Previous studies show that endothelial nitric oxide synthase (eNOS) facilitates vascular endothelial growth factor-mediated angiogenesis and increased vascular permeability. In contrast, recent work has shown that aged hemi-deficient hemizygous eNOS+/− mice manifest BBB disruption in association with increased incidence of thromboembolic events in the brain. To unravel whether eNOS contributes to or protects against hypoxia-induced cerebrovascular damage, we compared chronic mild hypoxia (CMH)-induced cerebrovascular angiogenic remodeling and BBB breakdown in aged (20 months old) eNOS+/− and wild-type (WT) mice. This revealed that CMH strongly enhanced eNOS expression in cerebral blood vessels with much lower levels in eNOS+/− mice. eNOS hemi-deficiency resulted in greater CMH-induced BBB disruption, but unexpectedly, had no effect on endothelial proliferation. eNOS+/− mice also displayed enhanced endothelial expression of the endothelial activation markers MECA-32, VCAM-1, and β3 integrin in cerebral blood vessels, indicating greater vascular inflammation, and this correlated with increased levels of microglial activation and demyelination. Taken together, our results support the concept that eNOS plays an important protective function in the aged brain by suppressing endothelial activation and maintaining cerebrovascular health
Data_Sheet_1_Activated Protein C Attenuates Experimental Autoimmune Encephalomyelitis Progression by Enhancing Vascular Integrity and Suppressing Microglial Activation.PDF
No full textBackgroundActivated protein C (APC), a serine protease with antithrombotic effects, protects in animal models of ischemic stroke by suppressing inflammation and enhancing vascular integrity, angiogenesis, neurogenesis and neuroprotection. A small number of animal studies suggest it might also have therapeutic potential in multiple sclerosis (MS), though results have been mixed. Based on these conflicting data, the goals of this study were to clarify the therapeutic potential of APC in the experimental autoimmune encephalomyelitis (EAE) model of MS and to determine mechanistically how APC mediates this protective effect.MethodsThe protective potential of APC was examined in a chronic progressive model of EAE. Vascular breakdown, tight junction protein expression and vascular expression of fibronectin and α5β1 integrin as well as vascularity and glial activation were analyzed using immunofluorescence (IF) of spinal cord sections taken from mice with established EAE. The direct influence of APC on microglial activation was evaluated in vitro by a combination of morphology and MMP-9 expression.ResultsAPC attenuated the progression of EAE, and this was strongly associated at the histopathological level with reduced levels of leukocyte infiltration and concomitant demyelination. Further analysis revealed that APC reduced vascular breakdown which was associated with maintained endothelial expression of the tight junction protein zonula occludens-1 (ZO-1). In addition, APC suppressed microglial activation in this EAE model and in vitro studies revealed that APC strongly inhibited microglial activation at both the morphological level and by the expression of the pro-inflammatory protease MMP-9.ConclusionThese findings build on the work of others in demonstrating strong therapeutic potential for APC in the treatment of inflammatory demyelinating disease and suggest that enhancement of vascular integrity and suppression of microglial activation may be important mediators of this protection.</p
W. R. Myers High School 2007
No full textThe annual publication of the students of W. R. Myers High School Taber, Alberta. (Volume 2006-2007)pdfr»~ g »:
"7;^mw - ^Ji^r<: •;^:.^»»*^/y7i^L^i^2^17LlALi^^On behalf of the yearbook class J would like to thank Mr, Dejong for allowing us time in school hours to complete the yearbook,
and all his dedication and hard work outside of class. J would like to thank the wonderful office staff for their countless hours of
proofing student names and filling us in on activities. Thank you to all staff for putting up with our "sneaky" candid picture snapping
throughout the school year and last but not least Lisa Mstalos for her moments of getting every one back in the game in her "own"
crazy way.
The year started out with a yearbook Conference in
Lethbridge. Ct was a long two days, which set the basis for
the next nine months. Only a few of us could attend but by the
end of the year you couldn't tell because everyone had mastered
the yeartech On-line Program!
Our theme this year was music and songs. Our very diverse
class presented us with a very diverse mix of music throughout
the book, mainly using the titles rather than the entire song.
.As Editor of the 2007 yearbook <7 was quite pleased to find a wonderful array of staff
and talent. For the first semester we had a rather large class but we made it work and
everyone's hard work payed off. Flundreds of hours later we are showcasing an amazing
book/ filled with memories talents and dreams of students come and gone.
Stefan Adams
Showing his
excitement at a
Rebels
Basketball Game
RE
Lets go
REBELS!
Students at the
pep rally in
March showing
their appreciation
for the Rebels
Kelsie Torrie
Showing oft her moves
while playing Dance
Dance Revolution at
the Pep Rally
Carolyn Sebok
Smashes the ball
earning her team a
point
Erin Valygardson
Was this years
mascot at all the
sports games.
Grade 10 Girls
Model their
hawaiian day
outfits during spirit
week.
Grade 9 Students
Digging a tunnel through
the pile of snow for
Outdoor Ed
Jordan Holst
Was one of the
Rebels biggest
fans this year.
3
y >s.,_^
Janet Jackson
Excited
Kevin Adams-White
Raegan Anderson
Randi-Jo Anderson
Carlynn Antoniuk
Travis Astalos
Ryley Baceda
Sara Barth
Owen Beers
Kate Bradbury
Shanel Brandies
Ryan Brill
Todd Bullock
Kori Christensen
Weston Coles
Jeffrey Courts
Jesse Debona
Kevin Deen
Myles Deibert
Dominique Ducharme
Matthew Erick
Hannah Ewen
Megan Fajnor
Rawan Farrage
Taylor Fitch
Dylan Fletcher
Paige Fletcher
Ryan Fletcher
Kimberley Gammelseter
Silvan Gansner
Hayley Gibson
5
Christine Harris
Bryan Hart
Darren Haslam
Curtis Huisman
Cassandra Hull
Katie-Lynn Jackson
Jeffrey Jensen
Jordan Jensen
Reagan Jensen
Tyler Johnson
Lynden Journoud
Tyneil Kerr
Marc Krushelnicki
Jennifer Lang
Mackenzie Lawson
Denis Lebeuf
Rylee Leth
Bailey Lewicki
Chad Lukacs
Kirstie Maerz
Logan Martin
Jeff McGann
Melony McLean
Ashley Meisner
Jovian Meissner
Cassandra Gilmore
Kelsey Habraken
Michelle Halifax
Tanner Hamilton
Clayton Hansen
6
Preston Miller
Jordan Moore
Michael Nakamura
Nicole Nilsson
Laura Noble
Ian Odland
Carlos Olave
Amanda Orsten
Jeffrey Oudman
Dominic Pahl
Karly Perin
Alisha Peters
Krystal Peters
Shaun Peters
Alyssa Peterson
Cassidy Powell
Amanda Robinson
Ashleigh Rombough
Joel Rombough
Mitchell Saruwatari
Justin Schmidt
Robi Schramm
Brandt Sebok
Amanda Sedgwick
Zak Shigemi
Casey Sims
Kenny Somerville
Phillip Stafford
Corey Thiessen
Austin Thomsen
7
Josh Vance
Kimberlee Vornbrock
Lachelle Vornbrock
Reid Walters
Christopher Weckesser
Kayla Williams
Jarvis Zazalack
Jun Zhen
Brooke Zimmer
Clayton Tilleman
Bradie Toth
Katie Tyo
Brooklyn Valgardson
Kristen Valgardson
8
(glamorous
Grade 10
Krystal
Jordan Brewin
Emily Bullock
Cara Campbell
Julie Campbell
Tom Chorney
Justin Colby
Ryan Colby
Brent Coles
Beth Conrad
Lindsy Corman
Blake Cousins
John Crawford
Anne-Marie Cromwellsmith
Adam Cunningham
Shellbee Cyr
Nick Allison
Larrisa Allred
James Andrus
Tim Ash
Johnny Badura
10
Stefan Bakoway-Adams
Kristen Bell
Kurt Bennett
Dustin Brewin
Janessa Brewin
Sarah Dalton
Kevin Dillman
Meagan Driedger
Georgia Drost
Jordan Drover
Lisa Elrick
Chris Evanson
Derek Evanson
Kyle Fehr
Andrew Fisher
Brittney Francom
Stephanie Girouard
Jayme Green
Larissa Groft
Tylin Haynes
Keely Heck
Stephanie Ho
Stephanie Hogan
Spencer Holst
Kasey Hoskins
Shane Hoyt
Ashley Huntley
Kayla Hutchison
Jessica Huys
Tyler Ikebuchi
11
JRiOW
Sara Kadoyama
Matt Karl
Sam Karras
Kyle Kast
Nolan Kinniburgh
Ashley Krahn
Ryan Kurtz
Jenna Lawson
Kelsey Lister
Tony Marsh
Scott Maruyama
Kristi Moore
Jimmy Neufeld
Tyrell Nielsen
Tara Norris
Brandon O'brien
Kyle O'brien
Kristen O'neill
Tori Odland
Tyrell Odland
Joshua Iwan
Ty Jensen
Bob Johnson
Kristie Johnson
Brandyn Just
t '
u.
K
Zachary Odland
Jenna Ohashi
Jessica Olave
Brittany Paun
Olivia Penner
Jac-Lyn Perrett
Brittney Peters
Gus Petrie
Jamie Petrie
Bryndin Phillips
Spencer Phillips
Jackson Pickerell
Jessica Pyrch
Troy Racz
Paige Reamsbottom
Brandon Redmond
Landyn Roberts
Jade Salkeld
Brett Schaafsma
Carol Sekura
Tessa Senkow
Karen Shufletoski
Ryan Spate
Ben Stang
Emily Steed
13
14
Nolan Thibodeau
Alyssa Thompson
Evan Thompson
Liam Thomson
Emily Tilleman
Bryan Turner
Delaney Vandersteen
Nicole VanMeetelen
Cody Vekony
Matthew Waldner
Charlotte Wargenau
Brooke Wentz
Ariel White
Chandra Wiebe
Aganethea Wieler
Brooke Ashley Wood
Erin Yamabe
Christopher Yokoyama
Maren Steed
Mathew Stoddart
Kasi Stonehouse
Amanda Tams
Haydon Tanner
i^^—^^^—^^^^^^^^^^ME- . L L. 11 !. /_:?•. '__________ 1 ' i J A 7 u , •
Working Overtime
Grade 11
Diana Ross
15
Sarah Baldry
Jamie Barrows
Jamie Batorski
Alison Bennett
Rai ven Boehmer
Shane Brandies
Emily Burt
Alicia Bydevaate
Jessie Campbell
Cassie Carle
Dillon Carswell
Matthew Chipman
Jodi Christensen
Lisa Coles
Chelsea Collett
Caleb Conrad
Jordan Conrad
Chelsea Courts
Blaine Daniels
Ashley Day
Karl Allison
Cortney Allred
Camille Anderson
Shaun Andrade
Amanda Baber
16
Brandon Derksen
Kayla Derksen
Sarah Drost
Danielle Ducharme
Ethan Ducharme
Eric Dunn
Kyle Edstrom
Trent Ellis
Riley Epp
Braden Fletcher
Lorna Foot
Vince Friesen
Kurtis Froehlick
Alyssa Gardner
Erik Gerlock
Nikki Gould
Nick Graves
Kelsey Guo
Jessica Hamilton
Cody Hammond
Melissa Harpell
Aimee Hughes
Alaina Hull
Karah Jensen
Jesse Johnson
17
Kristy Kaga
Tory Kallio
Michael Kano
Keylee Kast
David Koethler
Brittany Koomen
Clay Kurtz
Jamie Lawson
Eliza Layton
Jan Lei
Jamie Lemisko
Paige LePard
Ty LePard
Bao Yan Li
Sarah Lister
Tyson Lommerts
Blake Lowry
Skylar Matthews
Alex McCormick
Ethan McCrae
Brandy McPhee
Kelly Mills
Tessa Moline
Ryoji Nishihara
Paige Oberholtzer
18
^Ai
Jade Oczkowski
Matthew Osler
Alison Oudman
Kristin Oudman
Justin Pahl
Samantha Paradee
Megan Perin
Shanda Phillips
Kayla Plausteiner
Austin Powell-James
Amanda Procyk
Beth Regitnig
Garren Renner
Tim Robinson
Derek Rodwell
Brandon Schaufert
Lichelle Schmitz
Andrea Sebok
Carlyn Sebok
Jordan Sebok
Alexis Shigemi
Megan Skelly
Jessica Sorgard
Kelly Sran
Taylor Steed
19
Kelsey Torrie
Alicia Torsius
Jason Tycholis
Aaron Ulrick
CayLee Valgardson
Curtis Valgardson
Ashley Vowles
Melissa Walker
Logan Wentz
Jesse Williams
Bryan Wilson
Tyler Wilson
Angelica Wolf
Stephen Yokoyama
Nathan Zimmer
Wes Sugden
Samantha Tait
Luke Tams
Eric Thiessen
Wesley Tilleman
20
"Dare You To jMove"
Dwight
Richard
Allen-Vallee
AMB! Make an award winning record
label IDI DMX MMM! Everyday
with friends PPI When people pick
their noses in public NN! D~White BF!
Willie Rhodes
ID!Arnold Schwartzanagger NF!
Badshot Benny FM Teledega Nights
BF! My Mom GF! Gophers MMM!
When I passed chemistry
Benjamin
Wallace
Anderson
MEM! Getting my satellite radio back
NN! Chuckles FS! Keep the rubber
side down MMM'. Throwing pumpkins
at signs GF! Getting caught with my
pants down
BE Stepping in a bucket and getting it
stuck on my foot ID! Marcelle FS.
Thafs Ridiculous FCC! Winnie The Pooh
PF! Living in Antarctica FSS! Two
Princes by Spin Doctors BF! Traveling
Pants Gang GF! Being scared
Blake
Patrick
Andrus
AMB'. Become a teacher ID! Cher PP'.
When people refer to stuff as 'Gay NN!
Spider FS'. Indeed MEM'. When i fell
up the stairs FSS! Disposable Teens by
Marilyn Manson BF'. Paige Osburne
FA People watching
Dorian
Jay
Ayers
PP! Back seat drivers PF. Getting stuck
in Taber GF. Losing touch with friends
FSM! Hanging out with friends
Devan
James
Bathgate
Stephanie
Elizabeth
Ah
AMB! Become a doctor PP! Bad
grammar NN! The Pinball Wizard
FSS! Not Now by Blink 182 FM'. The
Last Kiss BF. Jess Peterson ID! Mr.
Dejong
Dave
Michael
Barth
MMM! Touring London and Paris
with EF Tours and the Marine Bio
boat trip NN! Jos FS! Whatever FSS!
Broken Wings FA Driving around
and listening to music GF! Leaving
Taber and actually missing it
Josulin
Marie
Beattie
Idol = ID Fav. School Song - FSS Ambition = AMB Fav. Saying FS Fav. Movie FM
Best Friend = BF Pet Peeve = PP Eick Name NN Fav. Activity FA Greatest Fear - GF
By: Switchfoot
BL Basketball trips IDI Leavitt MMM!
March 25 2006 PPI Slav drivers NN!
Berz FS1 What a mess! FOCI Donatello
(ninja turtle) FM'. The Sandlot
Reed
Robert K
ennedy
Berezay
PP! People who say get a lite NN!
Goggles FS! Rawr MEM! The
trampoline incident FM! Phantom at
the Opera BF! Niilo FA' Computers
Alexander
Ronald
Bosch
NN! Boosh, Danger, Ballin, Bavman
MMM! New years with Clay and
Kelsey FS.' That's Ballin GF! change
BL.' One word! Peter
Nicholas
Chase
Bowman
BL! Running over trees with a golf cart
MMM! Watching Kent try to ride a
horse PP! Super slow drivers NN! TJ
PF! Never leaving Taber BF! Travis
Tami-Jo
Colleen
Brewin
BL! Lyndon out at Trout NN! Bullock
PF! Working at Panago Lor the rest oL
my liLe GF! Not graduating
Brent
Joseph
Bullock
ID! Mr. D and my Grandpa NN!
Tower MEM! Missing a step going
down the stairs FA' Hanging out with
friends GF! Getting hit by a car BF!
The Robinsions and Devin Tarnasky
Devin
Eugene
Collett
ID! Colton Valgardson MMM!
Watching Ice Cube crab walk NN!
\Jerrdin MEM.'Colton gave me apple
\juice and i thought it was da bubbly
Jordan
Catherine
Cook
BL! Dallas's ideas PP! When people
dorit signal when driving FS! Live for
everything, die for nothing PF!Being
able to swim in a pool of money FA
skateboarding GF! Dying would suck
Mitchell
Glen
Davidson
Biggest Laugh BL Probable Fate - PF Most Memorable Moment MMM
Fav. Cartoon Character ; FCC Fav. School Memory - FSM Most Embarassing Moment MEM
23
"U Don't Wanna De"
Sean
Crawford
Dirk
AMB1 To achieve a career in a trade
NN1 Dirka Dirka FSS.' Blue Berry
Yum Yum by Ludacris FSM1 Hanging
out with friends
BL Writing to Mr. Cookie maker ID'.
Teach shes the greatest MH Mt Leaving
my car lights on and needing a boost
FCS'. Stay Beautiful by Taylor Swift
FM'. Benny and Joon. Pirates Of The
Caribbean (12). Harry Potter (12.3.4)
Jaycee
Pembrooke
Doolittle
BL1 Devan and I acting like idiots in
math and making silly noises AMB'.
Becoming a 2nd class Power Engineer
PPI People walking slowly in the
hallway and stopping in front of me
FSS1 Lips Of An Angel by Hinder
■ BL 7-11 creamers, talk about being
hyper FCC! Goob PF1 Working at
McDonalds for the rest of my life
FSM1 Band class Devan and Ty in the
back of Concert Band MMM1 Utah
road trip, too much candy
Tylan
Duke Michael
Dorohoy
Tommy
Mark
Doucette
Kent
Michael
Fehr
BL Getting stuck in a tree at trout
AMB1 Finish building my stock car
NN1 ButchyFSl Its not illegal until
you get caught
BL In Bio when Luch said 'A Cuckoo
Met A Pigeon AMB1 Be on the Honour
Role NN1 Phil. Fei FCC! Scooby Doo
MEM! Missing an easy shot in basket
ball FM1 Step Up BF.' Stephanie
Norris FAI Going to movies with friends
o
Felicia
Dawn
Fletcher
Travis
Blake
Fletcher
BL1 Taking the Honda to Trout with
Corey and Kent PPI Slow drivers NN!
Fletcher PF! Farming FM'. Talledaga
Nights BF! Tami and Lauray
AMB1 To be the best ditch digger ID!
My dad MMM1 Doing pranks PPI
Calgary Ski people FSM1 Shop Class
MEM.' Dumping my trucks oil outside
the school FM'. Dumb & Dumber BF1
My mom FAI snow boarding
Blaine
Bruce
Francis
Idol = ID Fav. School Song = FSS Ambition = AMB Fav. Saying = FS Fav. Movie FM
Best Friend BF Pet Peeve = PP Nick Name = 24 NN Fav. Activity - FA Greatest Fear GF
By:G«vin DeCiraw
AMB! To be a musician at Grant
McCewan ID'. Victor Lemonte Wooten
MMM! Getting my guitar PP.' When the
toilet is unflushed NN! Devo. Skinny
FCC! Spiderman, Ninja Turtles GF!
Waking up with a spider on my belly
Devan
Tyrel
Francom
BL! Jumping a car a trout BF! Shayne
Koncz GF! Not passing Highschool
Cori
Todd
Fritz
AMB! Go to school in Vancouver ID!
Jenny Penny Hoard PP! Anyone who
doesnt realize you re only young once
FA Snowboarding
Caitlin
Justina
Gammelseter
AMB! Be a mom ID! Celine Dion!!!
MMM! The adventures of Pixing PP!
Noise NN! Fly FSM!Friends MEM!
Junior High in general BF! Pookie FA
Anything that involves movement GF!
Killer Whales/! Dark Water!! and
trains!!
Breanne
Nicole
Garner
ABM! Get my drivers license PP!
Getting my stationary supplies stolen
FSM! The teachers FA Staying indoors
GF! Sunburns
Christina
Lee
Goeseels
MMM! Snoop Dogg Concert NN!
Gregus FCC! Peter Griffin FSM! Shop
FA Hanging out with friends GF!
Getting in a car accident
Jordan
Micheal
Gregus
BL! Grade 7 with Kasi and
VanessatWhat do horses eat?) AMB!
Professional umbrella twirler MMM!
Banff trip with Nikki and Erin and
the drunk Irish neighbor PP! People
blowing their noses GF! Wind chimes
and dark windows
Aexandra
Nicole
Hansen
Biggest Laugh =- BL Probable Fate - PF Most Memorable Moment =■ MMM
Fav. Cartoon Character = FCC Fav. School Memory - FSM Most Embarassing Moment - MEM 25
" Waiting On The World To Change
BL! Middle School- especially grade 71
The Superman song AMB! Be
incredibly successful and influential
MMM! Drunk Irishmen on the band
trip and mine and Lexies reaction PP!
People who dorit recycle juice boxes
FM! Harry Potter!
Erin
Elizabeth
Hansen
BL! Trumpetland AMB! Host a game
show ID! Steven Harper PP! Uni-brows
FCC! SpongeBob SquarePants
FSM! Breakfast club with Teach FM!
Star Wars FA! Snooping through
Teachs lunch
Brandon
Thomas
Hart
ID! Whitney Torrie PP! When Amanda
and her friends talk about Anime too
much NN! Twiddle Doo FCC! Mario.
Zelda. Peach and Luigi BF! Whitney
Torrie, Ashleigh Nelson
Kayl
Dawn
Hebig
PP! People who smell PF! Pro golfer
FM! Fear and Loathing in Las Vegas
GF! Being in Taber for the rest of my
life
ID! Muhammad Ali NN! Hutch FCC!
Captain Planet FSM! Sports FM!
Talledega N ights FA Basketball GF! To |
become poor
BL! When Marena comes over and
makes us laugh ID! Steve Irwin
MMM! The Tyrell Museum NN!
Panda Bear FCC! Neji FM!
Aquamarine BF! Amanda Jean FA!
Reading GF! My sister getting hurt
Amanda
Nicole
||| Harpell
Connor
Blake
Haslam
BL! People falling or tripping AMB!
Work with animals ID! Ray Charles
NN! Kimmy Rae FCC! Patrick Star PF!
Have a hundred animals and being
known as the cat lady FM! Never Been
Kissed GF! Getting eaten by a shark
Kimberly
Rae
AMB. To become successful in life PP.
Noisy eaters NN! D. Dagmar. Deg FCC!
Homer Simpson FSM! Spending time
with friends and getting to know
different people GF! Drowning
Daemund
Hugh David
Ingram
Idol = ID Fav. School Song = FSS Ambition = AMB Fav. Saying FS Fav. Movie FM
Best Friend BF Pet Peeve = PP Nick Name = NN Fav. Activity = FA Greatest Fear GF
26
By: 3ohn M«yoi*
BL.' TyDorohoy and Devan Francom
BlD!Tisha Murray MMM1 Finding
I Bobby NN! KJ Shorty Jensen FOCI
ISpongeBob PF! Marry a cowboy and
ride horses all my life FM! 8 Seconds
GF losing contact with good fnerds
after High School
Kasondra
Louise
Jensen >
ID! My brother Blair MMM! Hanging
with friends PP! People putting me
under pressure FSM! Being around
friends and people I enjoy FM! Little
Miss Sunshine GF! Not being happy in
my future
Matthew
John
Jimmy
BE Taking a taxi with Tami AMB!
Travel the world MMM! Night of my
17th birthday FM! Dirty Dancing BF!
Jordan Baker
Jori
Lynn
Jesper sen
BE When Kasi and I hid from Pat
MMM! Having a food fight in the
middle of the mall with Kayla PP!
Slow drivers FCC! Tweefy FSM!
Hanging out with friends GF! Not
Graduating
Brittany
Diane
Johnson
BL! When we wrote a love letter to Jeff
Bennett in grade 9 ID! Audrey
Hepburn MMM! My 17th birthday
PPI When people interrupt me NN!
Nikki FSl Oh bother FCC1 Belle PF1
Get married and be a housewife FM!
Breakfast at Tiffanys
Nicole
Diane
Johnson
AMB! Make it through High School
and University ID! Captain of the
Titanic FS! Sweet FCC! Doc Oct FSM!
Summer holidays PF! Carpenter/Civil
engineer FM! Pirates of the Caribbean
1 FA Football GF Losing to Winston
MMM! Cheering for the Oilers in
Daemunds van FSM! Leaving FSS!
Master Exploder Tenacious D FM!
Sin City GF! The Dentist
Davis
Garrett
Kambeitz
NN! Crackers FS'. How goes iff' FCC!
Bugs Bunny FSM! Spares FM! The
Grudge and Saw 2 FA Quadding and
driving
Michael
James
Karl
Biggest Laugh = BL Probable Fate = PF Most Memorable Moment = MMM
Fav. Cartoon Character = FCC Fav. School Memory = FSM Most Embarassing Moment = MEM
"Chasing Cars"
AMB.'To become an author and travel
the world ID! my Grandmother Karren
NN! Shorty FCC! Tigger FSM!
Cafeteria food MEM! I saidl got
straight but i meant I got it straight
FM! Sweet Home Alabama
Andrea
Jade
Karren
AMB! becoming a senile, crazy old lady
with a big purse ID! Jim Carrey NN!
Genie FS! Yup. True Story! FCC! Calvin
and Hobbes FSM! Drama FSS! This is
a New Shirt by Marilyn Manson FM!
X~Men
Gina
Judy
Kemp
Alam
Ronald
Kenyon
AMB! To make lots of money ID! John
Lennon MMM! Treasure Island. Grease
NN! Grumpy Gills NS! Rightous FCC!
Felix The Cat PF! Pumping gas FA
Acting
BE Amamdas Special question for
Mr. D AB! Togo to Fairview College
PP! When guys cross their legs like
girls NN! Christinkle. Kloker FS! Hey
ya 11 FCC! Sylvester the cat FSM! Mr.
Dejong FSS! That Girl Is A Cowboy
Christine
Leanne
Klok
AMB! To become a pediactric nurse ID!
my big brother PP! when people talk
with their mouths full FSM! Being
nervous to see people I usually wouldrit
MEM! When I fell in a puddle yelling
extra extra FA Scrapbooking
Meagan
Stacey
Koebel
FCC! Cartman GF! Becoming Jess FS!
Skillz Lawl ID! Dave PE Living in
taber all my life
Michael
Daniel
Koncz
Shayne
Dallyas
Koncz
AMB! To get out of Taber MMM!
Calgary trip with Daemund and
Lyndon NN! Two-step MEM! Getting
my eyebrows shaved off on New Years
NN! Tym FS! Scottys On Fire FM!
Dirty Dancing. Little Mis Sunshine BE
Shane Koncz making side kicks at
4!30 n the morning BE Kelsey T. FA
Dancing and being with friends
r Kymberly
Sandra
Krchnak
Idol = ID Fav. School Song = FSS Ambition = AMB Fav. Saying = FS Fav. Movie FM
Best Friend BF Pet Peeve = PP Nick Name NN Fav. Ativity FA Greatest Fear GF
28
By: Snow Patrol
BL Sitting on 'Cute Boys lap AM Bl To
live independently ID! Keith Urban
FM'. Grease PPI Being told "No NN! De
FS! Where is Daddy FCC! Mickey
Mouse FSM‘. Horse back riding BF'.
Dad FA Shopping
Dalanee
Blair
Leth
BL' In English with Andy Brad and
Amanda AMBi Master the guitar ID!
Al my friends NN! Rayman FSM'.
Friends FSS! Pain Three Days Grace
BFt Andy Brad GF! Not Graduating
Nathan
Archie Hubert
McNee
AMB! Be a good father ID! Civil
Servants and the Amed Forces PPI
Ignorant people FCC! Iron Hide FSM'.
Its about to end FMt Star Wars
Warren
Scott
Mitchell
BE Camping at Sherbern PPI Lazy
people NN1 Handy FCC! Peter Griffin
PF! Hostess lifer FM'. Viva La Bam
FA Basketball. Floor Hockey GE
Being called to the Office
BE Miss Schattles class NN! Doody
Henderson FS1 "Awesome, awesome to
the max FA Some kind of adventure
GFl Falling in love
Dallas
Llewellyn
McCrae
Andrew
John
Middelhoek
AMB! Become a chef ID! Emril
Lagrasse NN1 Moe Moe FS1 You need to
know the bitter before the sweet FOCI
Batman FSM! Friends FM'. The
Guardian BF'. Brandon. Mike. Gina,
Niilo. Chris FA Work
Tracy
Scott
Moline
BL.' Steph K at summer camp AMB'. To
make a difference in peoples lives!
MMM1 Jenna 0 wanting to skip art
for seminary PP.' People being fake
NN1 Tisha. Tish. Dish! FCC! Pinky and
the Brain FA Girls night in or out! GF!
Losing a friend that I couldht help
Letisha
Jean
Murray
BE Pulling the chair out from Brent
MMM1 Finding a hotel in Calgary
with Koncz and Daemund PF! Being a
farmer FA Playing hockey, snow
boarding, wake boarding
Lyndon
Rory
Nakamura
Biggest Laugh BL Probable Fate PF Most Memorable Moment^ MMM
Fav. Cartoon Character FCC Fav. School Memory ^ FSM Most Embarassing Moment : MEM
29
"My Wish"
Jylian
Dawnn
Lessman
bl: steph amb: Become rich and
famous MMM: Period 2 spare PP'.
Smelly people FSM'. My friends FM:
Casablanca BF'. The Traveling Pants
Gang GF! Losing touch with friends
NN1 Nemo FCC1 Garfield FA Spare.
Lunch. Spare
Justin
Markus
Niilo
BL.' Felicia and Chad burning me
AMBl To pass Math class ID! Clay
Aiken/! MMM1 When Chad fell down
the stairs NN! Claymate. StephyFCC.'
Goofy FM.' Bambi BF Felicia Dawn
Fletcher FA Basketball GF Getting fat
Stephanie
Dawn
Norris
AMBl To prove everybody wrong ID:
Sammy Marie-AKA Poodle MMM'.
September 9. 2005 PPI School toilet
paper NN1 Nuge. Nugey PF Principal
at W.R Myers
Amanda
Nicole
Nugent
Nicolle
Louise Jenine
OGrady
BL' Stage Band AMBl Paramedic. Fire
Fighter FS'. Johnny Depp is hott NN
Big M. Nicstifer MMM". Lunch Club.
Marcelles Party Night PPI Shoe-less
people ID! Neill
AMBl Play hockey after high school
and getting out of Taber FS'. Whats up
Budda? FCC. Garfield PF Attend
collie somewhere and take criminal
justice FSB! Bad Touch Blood Hound
Gang BF Adam Vanmeetelen GF. Living
with my parents till I'm 30
Courtney
Dawn
Odland
BL Singing My Humps" for Mr.
Hardings social class AMBl Become a
doctor MMM1 Licking a slug on
Marine Bio MEM'. Slipping on ice and
falling outside the school FA Figure
skating and soccer GF Getting old
Kesley
Kiyomi
Odland
Jordan
Blair
Oseen
NN1 Badger FS1 WHAT? AMBl Be rich
MMM1 Enchant BL' Shane Koncz GF'.
Sticking around Taber PF Living
somewhere warm, and having lots of
parties
Idol = ID Fav. School Song = FSS Ambition = AMB Fav. Saying = FS Fav. Movie = FM
Bes
