1,721,008 research outputs found

    Facial asymmetry and midsagittal plane definition in 3D: A bias-free, automated method.

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    Symmetry is a fundamental biological concept in all living organisms. It is related to a variety of physical and social traits ranging from genetic background integrity and developmental stability to the perception of physical appearance. Within this context, the study of human facial asymmetry carries a unique significance. Here, we validated an efficient method to assess 3D facial surface symmetry by best-fit approximating the original surface to its mirrored one. Following this step, the midsagittal plane of the face was automatically defined at the midpoints of the contralateral corresponding vertices of the superimposed models and colour coded distance maps were constructed. The method was tested by two operators using facial models of different surface size. The results show that the midsagittal plane definition was highly reproducible (maximum error < 0.1 mm or°) and remained robust for different extents of the facial surface model. The symmetry assessments were valid (differences between corresponding bilateral measurement areas < 0.1 mm), highly reproducible (error < 0.01 mm), and were modified by the extent of the initial surface model. The present landmark-free, automated method to assess facial asymmetry and define the midsagittal plane of the face is accurate, objective, easily applicable, comprehensible and cost effective

    Maxillary first molar extraction in Class II malocclusion: Follow-up studies on treatment effects

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    This PhD research investigated treatment effects of extraction of one and two maxillary first molars in Class II subdivision and Class II/1 malocclusion cases respectively from a longer time perspective. Private practice records were scrutinized to evaluate aspects of a treatment technique combining maxillary first molar extraction(s) and Begg brackets; outcome stability, influence on the position of maxillary third molars, interference of adjacent anatomical structures in closing extraction spaces, and effectiveness of fixed retainers in preventing vertical movement of mandibular second molars without contacts with maxillary teeth. Based on our results, extraction of a maxillary first molar and orthodontics led to favourable and stable results regarding aesthetics and occlusion. In patients treated with one and two extractions, the position of maxillary third molars improved by 3 to 4 times more compared to nonextraction maxillary halves and subjects. When applying this technique, clinicians should be aware of the possible interference of a large maxillary sinus in achieving upright position of maxillary second molars, and the capacity of retention wires to inhibit displacement of mandibular posterior teeth lacking occlusal contacts. Overall, there is evidence that maxillary first molar extraction(s) followed by orthodontic treatment, when carried out properly, and in selected cases, may be rewarding in clinical terms, and therefore may be preferred instead of extraction of premolars

    Morphological integration between the cranial base and the face in children and adults

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    The primary aim of the present study was to assess morphological covariation between the face and the basicranium (midline and lateral), and to evaluate patterns of integration at two specific developmental stages. A group of 71 children (6-10 years) was compared with a group of 71 adults (20-35 years). Lateral cephalometric radiographs were digitized and a total of 28 landmarks were placed on three areas; the midline cranial base, the lateral cranial base and the face. Geometric morphometric methods were applied and partial least squares analysis was used to evaluate correlation between the three shape blocks. Morphological integration was tested both with and without removing the effect of allometry. In children, mainly the midline and, to a lesser extent, the lateral cranial base were moderately correlated to the face. In adults, the correlation between the face and the midline cranial base, which ceases development earlier than the lateral base, was reduced. However, the lateral cranial base retained and even strengthened its correlation to the face. This suggests that the duration of common developmental timing is an important factor that influences integration between craniofacial structures. However, despite the apparent switch of primary roles between the cranial bases during development, the patterns of integration remained stable, thereby supporting the role of genetics over function in the establishment and development of craniofacial shape

    Number of teeth is associated with facial size in humans

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    During human evolution there has been an increase in the size of the brain and the cranium, whereas the size of the face, as well as the size and number of teeth have decreased. In modern humans, the occurrence of missing permanent teeth, namely tooth agenesis, is common. It could be attributed to a biological mechanism of tooth number reduction that has evolved during time and might still be active. Although, if evident, it would add support to this theory, the relationship between this phenotype and craniofacial size remains largely unknown. The present case-control study shows that modern individuals with tooth agenesis have indeed smaller facial configurations. For example, a 15-yearold female with no, one, or ten missing teeth would have a facial centroid size of 511.83, 510.81, or 501.70 mm, respectively. No such effect was observable in the cranial base and the cranium. Our results suggest that common gene regulatory mechanisms that have evolved over time, continue to regulate the number of teeth and facial size of modern humans in a coordinated manner. We anticipate our findings to enrich our understanding of the evolution and development of the human head and kindle future developmental research on this field

    Sociomedical and oral factors affecting masticatory performance in an older population.

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    OBJECTIVES To assess the sociomedical and oral factors affecting masticatory performance in a community-dwelling older population. MATERIALS AND METHODS Community-dwelling persons over 60 years were investigated using medical and dental oral interviews, oral and denture examination (natural teeth, tooth mobility, number of occluding tooth pairs, and removable dentures' prevalence and quality), and evaluation of masticatory performance using a mixing ability test. RESULTS A total of 130 participants with a mean age of 73.9±8.5 years were recorded. Fifty-eight (44.6%) used various types of removable prostheses. Twenty were edentulous and used a pair of complete dentures. Univariate analyses revealed statistically significant associations (p≤0.05) between masticatory performance and aging, marital status, subjective chewing ability, use of removable dentures, use of various combinations of complete dentures, pain caused by maxillary denture, number of teeth, tooth mobility, posterior chewing pairs, all chewing contacts natural or prosthetic, retention of mandibular partial dentures, and dentures' occlusion. The multivariable quantile regression analysis revealed that fewer natural teeth (95% CI: -0.02-0.01, p<0.001), being edentulous and using a pair of complete dentures (95% CI: 0.09-0.35, p=0.001), and larger percentage of severely mobile teeth (95% CI: 0.07-0.82, p=0.020) were associated with lower masticatory performance. CONCLUSIONS Poor masticatory performance in older adults was associated with fewer teeth, being edentulous and using a pair of complete dentures, and increased prevalence of severe tooth mobility. CLINICAL RELEVANCE Retaining the natural dentition and preventing and treating periodontal disease are important measures to maintain masticatory performance in older adults

    The effect of threshold level on bone segmentation of cranial base structures from CT and CBCT images.

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    The use of a single grey intensity threshold is one of the most straightforward and widely used methods to segment cranial base surface models from a 3D radiographic volume. In this study we used thirty Cone Beam Computer Tomography (CBCT) scans from three different machines and ten CT scans of growing individuals to test the effect of thresholding on the subsequently produced anterior cranial base surface models. From each scan, six surface models were generated using a range of voxel intensity thresholds. The models were then superimposed on a manually selected reference surface model, using an iterative closest point algorithm. Multivariate tests showed significant effects of the machine type, threshold value, and superimposition on the spatial position and the form of the created models. For both, CT and CBCT machines, the distance between the models, as well as the variation within each threshold category, was consistently increasing with the magnitude of difference between thresholds. The present findings highlight the importance of accurate anterior cranial base segmentation for reliable assessment of craniofacial morphology through surface superimposition or similar methods that utilize this anatomical structure as reference

    The effect of regular dental cast artifacts on the 3D superimposition of serial digital maxillary dental models

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    Superimpositions of serial 3D dental surface models comprise a powerful tool to assess morphological changes due to growth, treatment, or pathology. In this study, we evaluated the effect of artifacts on the superimposition outcome, using standard model acquisition and superimposition techniques. Ten pre- and post-orthodontic treatment plaster models were scanned with an intraoral scanner and superimposed using the iterative closest point algorithm. We repeated the whole process after manual removal of plaster artifacts, according to the current practice, as well as after re-scanning the cleaned models, to assess the effect of the model acquisition process derived artifacts on the superimposition outcome. Non-parametric multivariate models showed no mean effect on accuracy and precision by software settings, cleaning status (artifact removal), or time point. The choice of the superimposition reference area was the only factor that affected the measurements. However, assessment of individual cases revealed significant differences on the detected tooth movement, depending on artifact removal and on the model acquisition process. The effects of all factors tended to decrease with an increase in the size of the superimposition reference area. The present findings highlight the importance of accurate, artifact-free models, for valid assessment of morphological changes through serial 3D model superimpositions

    Influence of unilateral maxillary first molar extraction treatment on second and third molar inclination in Class II subdivision patients.

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    OBJECTIVE To assess the maxillary second molar (M2) and third molar (M3) inclination following orthodontic treatment of Class II subdivision malocclusion with unilateral maxillary first molar (M1) extraction. MATERIALS AND METHODS Panoramic radiographs of 21 Class II subdivision adolescents (eight boys, 13 girls; mean age, 12.8 years; standard deviation, 1.7 years) before treatment, after treatment with extraction of one maxillary first molar and Begg appliances and after at least 1.8 years in retention were retrospectively collected from a private practice. M2 and M3 inclination angles (M2/ITP, M2/IOP, M3/ITP, M3/IOP), constructed by intertuberosity (ITP) and interorbital planes (IOP), were calculated for the extracted and nonextracted segments. Random effects regression analysis was performed to evaluate the effect on the molar angulation of extraction, time, and gender after adjusting for baseline measurements. RESULTS Time and extraction status were significant predictors for M2 angulation. M2/ITP and M2/IOP decreased by 4.04 (95% confidence interval [CI]: -6.93, 1.16; P  =  .001) and 3.67 (95% CI: -6.76, -0.58; P  =  .020) in the extraction group compared to the nonextraction group after adjusting for time and gender. The adjusted analysis showed that extraction was the only predictor for M3 angulation that reached statistical significance. M3 mesial inclination increased by 7.38° (95% CI: -11.2, -3.54; P < .001) and 7.33° (95% CI: -11.48, -3.19; P  =  .001). CONCLUSIONS M2 and M3 uprighting significantly improved in the extraction side after orthodontic treatment with unilateral maxillary M1 extraction. There was a significant increase in mesial tipping of maxillary second molar crowns over time
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