31,427 research outputs found
Thomas Grisell letter to Thomas Rotch, 2nd mo 19th 1823
No full textThomas Grisell's letter reached the Rotch household several months before the unexpected death of Thomas Rotch in August, 1823. This is the last letter of the series and presumably the author learned of his friend's death before another letter was penned. 7.95" x 10" (20.2 by 25.5 cm
Failed Censures: Ecclesiastical Regulation of Women’s Clothing in Late Medieval Italy
No full textChurchmen in the late thirteenth and early fourteenth centuries tried to regulate the costume of Italian women. These efforts failed, and regulation was largely left thereafter to civic authorities.The published version was published as Chapter 3 in Medieval Clothing and Textiles 5Izbicki, Thomas M. (2009), "Failed Censures: Ecclesiastical Regulation of Women’s Clothing in Late Medieval Italy" in Netherton, Robin and Owen-Crocker, Gale R., eds., Medieval Clothing and Textiles 5 (Boydell Press), 37-53ISBN: 9781843834519 (published book)Peer reviewe
Western medieval legal manuscripts in the collections of the University of Pennsylvania
No full textWestern legal manuscripts of the Middle Ages in North American collections are among the least known to scholars. The University of Pennsylvania has a rich collection of these texts, several of which were in the collection of the historian Henry Charles Lea. Included are works of civil law and canon law, as well as collections of papal letters and guides to pastoral care. The descriptions of most of these manuscripts in the catalog of Norman P. Zacour and Rudolf Hirsch are perfunctory, sometimes erring or omitting valuable information. Other manuscripts were added in recent years in the Lawrence J. Schoenberg Collection. Much of this material is being added to the Franklin online catalog of the University’s libraries, but researchers frequently do not search these digital resources. This article provides more complete guidance to the University’s medieval legal manuscripts than any of the existing catalogs offers, whether in print or online. It also provides updated bibliographic information in print or online. Every manuscript has been examined by the author in situ. Among the important works represented in the collection is the Panormia (a work of canon law often attributed to Ivo of Chartres). Authors present include the curialist Thomas of Capua, canonists Petrus de Braco, William of Pagula, Bernardus Raimundi, Adam of Aldersbach, Raymond of Peñafort, and civil lawyers Baldus de Ubaldis, and Bartolus de Saxoferrato. Three of these manuscripts were owned in the past by Sir Thomas Phillipps
Forbidden Colors in the Regulation of Clerical Dress from the Fourth Lateran Council (1215) to the Time of Nicholas of Cusa (d. 1464)
No full textMedieval canon law attempted to distinguish clergy from the laity by restricting their dress choices. The article focuses on prohibition of wearing red or green on the street. Both colors were identified with the nobility.The published version was published as Chapter 7 in Medieval Clothing and Textiles 1Izbicki, Thomas M. (2005), "Forbidden Colors in the Regulation of Clerical Dress from the Fourth Lateran Council (1215) to the Time of Nicholas of Cusa (d. 1464)" in Netherton, Robin and Owen-Crocker, Gale R., eds., Medieval Clothing and Textiles 1 (Boydell Press),105-114ISBN: 9781843831235 (published book
Thomas Crutchfield account book, 1848-1861
No full textA book containing business accounts, including details about travel expenses and the purchase and sale of lumber as well as other goods and services. The author also catalogs personal spending, the dates and pricing of properties offered for rent, and the purchase and leasing of enslaved people. Many entries are consistent with the business activities of Thomas Crutchfield Sr., who died in 1850. Someone continued to make entries in the book for activities dated up to 1861
Thomas Crutchfield account book, 1848-1861
No full textA book containing business accounts, including details about travel expenses and the purchase and sale of lumber as well as other goods and services. The author also catalogs personal spending, the dates and pricing of properties offered for rent, and the purchase and leasing of enslaved people. Many entries are consistent with the business activities of Thomas Crutchfield Sr., who died in 1850. Someone continued to make entries in the book for activities dated up to 1861
Thomas Hazard Jr letter to Thomas Rotch, New York 6 mo 10, 1821
No full textThe author acknowledges receipt of letters after the Rotch return to Kendal, Ohio in the late spring of 1821. Thomas Hazard mentions that his whaling ship, Dawn, has sailed to the Pacific Ocean with 23 hands on board and provisions for three years. He hopes to visit Kendal in the Fall, he also mentions that William Rotch Jr was recovering from a fever.
7.9" x 10" (20 by 25.5 cm
Der Einfluss des Hypoxie-induzierbaren Faktors (HIF) auf tumorrelevante Zellfunktionen
No full textThe purpose of this thesis was to find out, how the stabilisation of HIF affects cellular functions which could contribute to the development of tumours. The aim of the first part of this work was the establishment of a transgenic mouse model with renal, tubular specific and oxygen independent stabilisation of HIF-1alpha in order to analyse the tumourigenic potential of HIF-1 on kidney cells. The second part of this work describes the characterisation of a new HIF-1 target gene Rab20. The last part comprises the successful generation of tetracycline inducible, HIF-1alpha and HIF-2alpha expressing cell lines. All together, the results clearly demonstrate, that HIF targets many different aspects of cellular function. The data show that activation of HIF directly influences apoptosis and cell cycle regulation. Both processes are inevitably linked to the development of tumours. Therefore, this work highlights important aspects of how HIF could influence tumour behaviour.Ziel dieser Arbeit war die Aufklärung, wie sich die Stabilisierung von HIF auf wichtige zellbiologische und vor allem für die Entstehung von Tumoren relevante Prozesse auswirkt. Durch die Etablierung eines transgenen Mausmodels mit renaler, Tubulus spezifischer und Sauerstoff unabhängiger Stabilisierung von HIF-1alpha, sollte das tumorigene Potential von HIF 1 auf gesunde Nierenzellen untersucht werden. In dem zweiten Teilabschnitt dieser Arbeit konnte mit Rab20 ein neues, zuvor unbekanntes Zielgen von HIF-1 charakterisiert werden. Im letzten Teilabschnitt dieser Arbeit wurden erfolgreich Zelllinien generiert, in denen die Expression von HIF-1alpha oder HIF-2alpha durch Gabe eines Antibiotikums gezielt aktiviert werden kann. Die vorgelegten neuen Erkenntnisse demonstrieren, dass vielschichtige Aspekte zellulärer Funktion durch den Transkriptionsfaktor HIF direkt beeinträchtigt werden. So zeigen die dargestellten Daten einen eindeutigen Einfluss von HIF auf die Apoptose und Zellzyklusregulation. Beide Prozesse sind unweigerlich mit der Entwicklung von Tumoren verknüpft. Mit dieser Arbeit konnten somit wichtige Aspekte zum Einfluss von HIF auf die Tumorbiologie näher beleuchtet werden
Thomas of Marga's Monastic History and Other Texts
No full textBedjan here offers in his customary manner (i.e. in fully vocalized east Syriac script) several texts: Thomas of Marga’s Monastic History of Bet ‘Abe (also known as the Book of Governors), ‘Ishodnah’s Book of Monastery Founders, Homilies on Joseph by Narsai, and a collection of texts from Leo the Great (the Tome), Nestorius, Sahdona (Martyrius), and the Testament of St. Ephrem (in a different redaction than those previously published). The volume is prefaced with an introduction in French. This range of materials will be of interest to every reader concerned with the theology and history of Syriac Christianity.Includes introduction in French
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