19 research outputs found
Evaluation of CRP as a marker for bacterial infection and malaria in febrile children at the Douala Gyneco-Obstetric and Pediatric Hospital.
No full textBackgroundC reactive protein (CRP), a marker for the presence of inflammation, has been extensively studied for distinguishing bacterial from non-bacterial infection in febrile patients, but its role in excluding malaria in the febrile child has not been thoroughly evaluated.MethodThis was a cross-sectional study at the Douala Gyneco-Obstetric and Pediatric Hospital which included all patients between the ages of one month and 16 years presenting with fever. Consenting patients received complete clinical examinations, then venous blood samples were collected and tested for CRP values, bacterial infection and malaria.ResultsSamples of 220 children were analyzed. 142/220 had viral infections, 50/220 had malaria and 49/220 had bacterial infections. 7/220 had both malaria and bacterial infection. There was no significant difference between mean CRP values in malaria and bacterial infection (p = 1), but CRP means were significantly higher in malaria/bacterial infection than in viral infection (pConclusionCRP can effectively exclude malaria and bacterial infection in febrile children in low-resource settings without the need for additional tests
Evaluation des activités anti-inflammatoire et antiradicalaire de l’extrait au vin de palme des feuilles de <i>Phragmanthera capitata</i> (Sprengel) S. Balle (Loranthaceae) récoltées sur <i>Psidium guajava</i> au Cameroun
No full textS1 Database -
No full textBackgroundC reactive protein (CRP), a marker for the presence of inflammation, has been extensively studied for distinguishing bacterial from non-bacterial infection in febrile patients, but its role in excluding malaria in the febrile child has not been thoroughly evaluated.MethodThis was a cross-sectional study at the Douala Gyneco-Obstetric and Pediatric Hospital which included all patients between the ages of one month and 16 years presenting with fever. Consenting patients received complete clinical examinations, then venous blood samples were collected and tested for CRP values, bacterial infection and malaria.ResultsSamples of 220 children were analyzed. 142/220 had viral infections, 50/220 had malaria and 49/220 had bacterial infections. 7/220 had both malaria and bacterial infection. There was no significant difference between mean CRP values in malaria and bacterial infection (p = 1), but CRP means were significantly higher in malaria/bacterial infection than in viral infection (pConclusionCRP can effectively exclude malaria and bacterial infection in febrile children in low-resource settings without the need for additional tests.</div
Distribution of CRP levels according to final diagnosis.
No full textDistribution of CRP levels according to final diagnosis.</p
Influence of ABO Blood Groups on Plasmodium falciparum Parasitaemia and Malaria Clinical Types in Outpatients in a Government Hospital of Douala, Cameroon
No full textFacteurs de risque de mortalité chez les patients tuberculeux surinfectés par le VIH à Douala (Cameroun).
No full textDespite prevention efforts, and free treatment, TB-HIV co-infection still occurs in Cameroon. The objective of this work is to present the risk factors for mortality in patients co-infected with TB and HIV in Douala from 2009 to 2014. This transversal, analytic, and retrospective study took place from November 2014 to May 2015 in the Laquintinie Hospital in Douala. A review of our records identified patients aged at least 15 years, with this co-infection who received TB treatment, with or without antiretroviral agents. The bivariate analysis compared qualitative variables with Pearson's Chi2 test. In the multivariate analysis, we determined the risk factors for mortality by backward stepwise logistic regression. Model fit was tested with the Hosmer-Lemeshow test. The study identified 394 patients, 213 (54.1%) of whom were women (sex ratio 0.84). The mean age was 39 ± 10 years. All patients received drugs to treat tuberculosis drugs; 351 (89%) also received antiretroviral drugs, 78.2% of them including efavirenz; and 320 (81.2%) received cotrimoxazole prophylaxis. During the study period, 67.3% were cured of tuberculosis and 15.7% died. The multivariate regression results show that hepatitis B (P <0.0009), absence of cotrimoxazole prophylaxis (P <0.005), poor treatment adherence (P <0.0001), and a CD4 count <50 (P <0.0001) were risk factors for mortality. The cure rate for patients co-infected with TB and HIV in Cameroon remains low, and their mortality high. Comorbidities and the presence of opportunistic diseases are risk factors for death. Appropriate measures to prevent this co-infection and the systematic use of cotrimoxazole should reduce this mortality rate.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
Devenir des Patients Tuberculeux Transférés / Référés d’un Centre de Pneumo-phtisiologie vers des Centres de Traitement Périphériques :Une étude de 359 patients à Douala
No full textinfo:eu-repo/semantics/publishe
Positive and negative values for CRP and bacterial infection using optimal cut-off.
No full textPositive and negative values for CRP and bacterial infection using optimal cut-off.</p
Demographic and clinical characteristics of the study population.
No full textDemographic and clinical characteristics of the study population.</p
