259 research outputs found
Figure_S3 – Supplemental material for Load transfer across a mandible during a mastication cycle: The effects of odontogenic tumour
No full textSupplemental material, Figure_S3 for Load transfer across a mandible during a mastication cycle: The effects of odontogenic tumour by Abir Dutta, Kaushik Mukherjee, Venkata Sundeep Seesala, Kaushik Dutta, Ranjan Rashmi Paul, Santanu Dhara and Sanjay Gupta in Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine</p
Figure_S4 – Supplemental material for Load transfer across a mandible during a mastication cycle: The effects of odontogenic tumour
No full textSupplemental material, Figure_S4 for Load transfer across a mandible during a mastication cycle: The effects of odontogenic tumour by Abir Dutta, Kaushik Mukherjee, Venkata Sundeep Seesala, Kaushik Dutta, Ranjan Rashmi Paul, Santanu Dhara and Sanjay Gupta in Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine</p
Figure_S1 – Supplemental material for Load transfer across a mandible during a mastication cycle: The effects of odontogenic tumour
No full textSupplemental material, Figure_S1 for Load transfer across a mandible during a mastication cycle: The effects of odontogenic tumour by Abir Dutta, Kaushik Mukherjee, Venkata Sundeep Seesala, Kaushik Dutta, Ranjan Rashmi Paul, Santanu Dhara and Sanjay Gupta in Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine</p
Figure_S2 – Supplemental material for Load transfer across a mandible during a mastication cycle: The effects of odontogenic tumour
No full textSupplemental material, Figure_S2 for Load transfer across a mandible during a mastication cycle: The effects of odontogenic tumour by Abir Dutta, Kaushik Mukherjee, Venkata Sundeep Seesala, Kaushik Dutta, Ranjan Rashmi Paul, Santanu Dhara and Sanjay Gupta in Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine</p
Green Wireless Access Networks
No full textI Godor, P Frenger, H Holtkamp, M Imran, A Vidacs, P Fazekas, D Sabella, E Strinati, R Gupta, P Pirinen and A Fehsk
Green Wireless Access Networks
No full textI Godor, P Frenger, H Holtkamp, M Imran, A Vidacs, P Fazekas, D Sabella, E Strinati, R Gupta, P Pirinen and A Fehsk
Auxeticity in biosystems: an exemplification of its effects on the mechanobiology of heterogeneous living cells
No full textAuxeticity (negative Poisson’s ratio) is the unique mechanical property found in an extensive variety of materials, such as metals, graphene, composites, polymers, foams, fibers, ceramics, zeolites, silicates and biological tissues. The enhanced mechanical features of the auxetic materials have motivated scientists to design, engineer and manufacture man-made auxetic materials to fully leverage their capabilities in different fields of research applications, including aeronautics, medical, protective equipments, smart sensors, filter cleaning, and so on. Atomic force microscopy (AFM) indentation is one of the most widely used methods for characterizing the mechanical properties and response of the living cells. In this contribution, we highlight main consequences of auxeticity for biosystems and provide a representative example to quantify the effect of nucleus auxeticity on the force response of the embryonic stem cells. A parametric study has been conducted on a heterogeneous stem cell to evaluate the effect of nucleus diameter, nucleus elasticity, indenter’s shape and location on the force-indentation curve. The developed model has also been validated with the recently reported experimental studies available in the literature. Our results suggest that the nucleus auxeticity plays a profound role in cell mechanics especially for large size nucleus. We also report the mechanical stresses induced within the hyperelastic cell model under different loading conditions that would be quite useful in decoding the interrelations between mechanical stimuli and cellular behavior of auxetic biosystems. Finally, current and potential areas of applications of our findings for regenerative therapies, tissue engineering, 3 D/4D bioprinting, and the development of meta-biomaterials are discussed
Coupled multiphysics modelling of sensors for chemical, biomedical, and environmental applications with focus on smart materials and low-dimensional nanostructures
No full textLow-dimensional nanostructures have many advantages when used in sensors compared to the traditional bulk materials, in particular in their sensitivity and specificity. In such nanostructures, the motion of carriers can be confined from one, two, or all three spatial dimensions, leading to their unique properties. New advancements in nanosensors, based on low-dimensional nanostructures, permit their functioning at scales comparable with biological processes and natural systems, allowing their efficient functionalization with chemical and biological molecules. In this article, we provide details of such sensors, focusing on their several important classes, as well as the issues of their designs based on mathematical and computational models covering a range of scales. Such multiscale models require state-of-the-art techniques for their solutions, and we provide an overview of the associated numerical methodologies and approaches in this context. We emphasize the importance of accounting for coupling between different physical fields such as thermal, electromechanical, and magnetic, as well as of additional nonlinear and nonlocal effects which can be salient features of new applications and sensor designs. Our special attention is given to nanowires and nanotubes which are well suited for nanosensor designs and applications, being able to carry a double functionality, as transducers and the media to transmit the signal. One of the key properties of these nanostructures is an enhancement in sensitivity resulting from their high surface-to-volume ratio, which leads to their geometry-dependant properties. This dependency requires careful consideration at the modelling stage, and we provide further details on this issue. Another important class of sensors analyzed here is pertinent to sensor and actuator technologies based on smart materials. The modelling of such materials in their dynamics-enabled applications represents a significant challenge as we have to deal with strongly nonlinear coupled problems, accounting for dynamic interactions between different physical fields and microstructure evolution. Among other classes, important in novel sensor applications, we have given our special attention to heterostructures and nucleic acid based nanostructures. In terms of the application areas, we have focused on chemical and biomedical fields, as well as on green energy and environmentally-friendly technologies where the efficient designs and opportune deployments of sensors are both urgent and compelling.Natural Sciences and Engineering Research Council (NSERC) of CanadaCanada Research Chairs (CRC) Progra
A commercial approach towards fabrication of bulk and nano phosphors converted highly-efficient white LEDs
No full textHerein, we report a strategy to synthesize a highly efficient yellow light emitting Y3−xAl5O12:Cex (x = 0.03 to 0.3) based bulk as well as nano (rod-shaped) phosphors, which are the main component of solid state white light-emitting diodes (WLEDs). The as-synthesized phosphors were well characterized by several experimental techniques related to material characterization and spectroscopy. The bulk and nano phosphors emit with maximum photoluminescence intensities at 549 and 530 nm, respectively, upon excitation at a wavelength of 468 nm. These phosphors exhibit higher photoluminescence intensity as compared to commercially available bulk phosphors coated on WLED strips. Moreover, the integration of commercially available InGaN blue LED strips with the synthesized bulk and nano phosphors demonstrates better CIE coordinates and lower colour temperature with high brightness (>81% quantum yield) compared to commercially available WLED-based strips, lanterns and torches. These highly efficient light-emitting phosphors are a feasible candidate for potential use in commercial WLED applications
Fluid–structure interaction and non-fourier effects in coupled electro-thermo-mechanical models for cardiac ablation
No full textIn this study, a fully coupled electro-thermo-mechanical model of radiofrequency (RF)-assisted cardiac ablation has been developed, incorporating fluid–structure interaction, thermal relaxation time effects and porous media approach. A non-Fourier based bio-heat transfer model has been used for predicting the temperature distribution and ablation zone during the cardiac ablation. The blood has been modeled as a Newtonian fluid and the velocity fields are obtained utilizing the Navier–Stokes equations. The thermal stresses induced due to the heating of the cardiac tissue have also been accounted. Parametric studies have been conducted to investigate the effect of cardiac tissue porosity, thermal relaxation time effects, electrode insertion depths and orientations on the treatment outcomes of the cardiac ablation. The results are presented in terms of predicted temperature distributions and ablation volumes for different cases of interest utilizing a finite element based COMSOL Multiphysics software. It has been found that electrode insertion depth and orientation has a significant effect on the treatment outcomes of cardiac ablation. Further, porosity of cardiac tissue also plays an important role in the prediction of temperature distribution and ablation volume during RF-assisted cardiac ablation. Moreover, thermal relaxation times only affect the treatment outcomes for shorter treatment times of less than 30 s.Natural Sciences and Engineering Research Council (NSERC) of CanadaCanada Research Chairs (CRC) Progra
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