1,236 research outputs found
sj-docx-1-aum-10.1177_03128962211059579 – Supplemental material for Research on unhealthy food and beverages advertising targeting children: Systematic literature review and directions for future research
No full textSupplemental material, sj-docx-1-aum-10.1177_03128962211059579 for Research on unhealthy food and beverages advertising targeting children: Systematic literature review and directions for future research by Ritu Srivastava and Parul Gupta in Australian Journal of Management</p
Supplemental Material - Global Status of Knowledge, Attitude and Practice on Tobacco Cessation Interventions Among Dental Professionals: A Systematic Review
No full textSupplemental Material for Global Status of Knowledge, Attitude and Practice on Tobacco Cessation Interventions Among Dental Professionals: A Systematic Review by Harsh Priya, Manali Deb Barma, Bharathi M Purohit, Deepali Agarwal, Upendra Singh Bhadauria, Nitesh Tewari, Shalini Gupta, Deepika Mishra, Rahul Morankar, Vijay Prakash Mathur and Ritu Duggal in Tobacco Use Insights</p
Supplemental Material - Global Status of Knowledge, Attitude and Practice on Tobacco Cessation Interventions Among Dental Professionals: A Systematic Review
No full textSupplemental Material for Global Status of Knowledge, Attitude and Practice on Tobacco Cessation Interventions Among Dental Professionals: A Systematic Review by Harsh Priya, Manali Deb Barma, Bharathi M Purohit, Deepali Agarwal, Upendra Singh Bhadauria, Nitesh Tewari, Shalini Gupta, Deepika Mishra, Rahul Morankar, Vijay Prakash Mathur and Ritu Duggal in Tobacco Use Insights</p
Nanoscale visualization of high-angle misorientations in quartz-rich rocks using SEM-EBSD and Atomic Force Microscopy
No full textHigh-angle misorientations can significantly influence material properties. In this study, optical microscopy, Scanning Electron Microscope-Electron Backscatter Diffraction (SEM-EBSD), and Atomic Force Microscopy (AFM) have been used to investigate high-angle misorientations in quartz-bearing crustal rocks. Thin sections of high-grade quartzofeldspathic rocks were subjected to chemical mechanical polishing (CMP) with colloidal silica. In quartz, high-angle misorientations like random high angle grain boundaries (RHAGBs) and Dauphiné twin boundaries (DTBs) could be discriminated using EBSD techniques but not optical microscopy. In nanoscale AFM images, indented channels are observed along RHAGBs but not DTBs; these result from material removal during CMP, indicating lower compactness of RHAGBs compared to DTBs. Along any RHAGB, EBSD reveals different misorientations across segments between consecutive RHAGB-DTB intersections. Grains adjacent to these RHAGB segments have angles between their c-axes varying from 61-66° with parallel {101 ̅2} planes, and 81–84° with parallel {112 ̅2} planes, respectively. These symmetries represent the Japan and Sardinian twin laws of quartz, indicating that the RHAGB segments become low-energy twin boundaries, thereby reducing the overall surface energy of the aggregate. Finally, these results suggest that apart from surface topography quantification and high-resolution nanoscale imaging, AFM in conjunction with SEM-EBSD can be used for precisely locating sites for TEM study
Comment on: Comfort After Refitting Symptomatic Habitual Reusable Toric Lens Wearers with a New Daily Disposable Contact Lens for Astigmatism [Letter]
No full textSuraj Kumar Chaurasiya,1,2 Mahendra Singh,1 Ritu Ray1 1Department of Optometry and Vision Science, CL Gupta Eye Institute, Moradabad, UP, 244001, India; 2Department of Contact Lens and Anterior Segment, CL Gupta Eye Institute, Moradabad, UP, 244001, IndiaCorrespondence: Suraj Kumar Chaurasiya, CL Gupta Eye Institute, Ram Ganga Vihar Phase II (Extn), Moradabad, UP, 244001, India, Tel +91-8809893186, Email [email protected]
Win 068
No full textNational Health Law Moot Court Competition held at Southern Illinois University School of Law, Carbondale, Illinois. The team consisted of Frank J. Battaglia, Terri M. Durrett and Ritu Gupta
Abstract 3482: SNORD-X in glioblastoma: regulation and functional analysis
No full textAbstract
Glioblastoma Multiforme (GBM) is a kind of brain tumor which arises from astrocytes present in the brain. It represents approximately 15% of all primary brain tumor and has been considered as one of the deadliest type of cancer with very poor prognosis. Thus, there is an urgent need to identify novel targets for GBM therapy. Recently, non-coding RNAs (ncRNAs) such as miRNAs and lncRNAs have emerged as one of the promising tools as diagnostic or prognostic biomarkers and as novel targets for therapy. There are recent evidences that small nucleolar RNAs (snoRNAs), a subtype of ncRNAs might also play a key role in various cancers. In this context, we aimed at studying the role of snoRNAs in GBM. For this, we did snoRNA profiling in GBM patients and found that a particular cluster of snoRNA called SNORD-X was highly downregulated in adult as well as pediatric GBM patients. We also found SNORD-X promoter to be methylated and shows maternal imprinting. We next did functional analyses of SNORD-X by generation of an overexpression construct. Our preliminary data suggests that overexpression of SNORD-X in GBM cell lines (U87MG and A172) increases cell proliferation in vitro. It also enhances the colony forming capability of GBM cells. Further, its overexpression causes decrease in apoptosis in a caspase-dependent manner. A target analysis of SNORD-X was done using RNAhybrid software. We found EGR1, DCUN1D3 and BRCA1 to be the direct targets of SNORD-X using a combination of qRT-PCR and wild-type/mutated 3’UTR luciferase analyses. Overall, our work shows for the first time correlation and functional analysis of SNORD-X cluster in GBM.
Citation Format: Shikha Gupta, Prerana Jha, Chitra Sarkar, Ritu Kulshreshtha. SNORD-X in glioblastoma: regulation and functional analysis [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 3482. doi:10.1158/1538-7445.AM2017-3482</jats:p
3D printed muscle-powered bio-bots
Get PDFSubmission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2018-12-01Complex biological systems sense, process, and respond to a range of environmental signals in real-time. The ability of such systems to adapt their functional response to dynamic external signals motivates the use of biological materials in other engineering applications. Recent advances in 3D printing have enabled the manufacture of complex structures from biological materials. We have developed a projection stereolithographic 3D printing apparatus capable of patterning cells and biocompatible polymers at physiologically relevant length scales, on the order of single cells. This enables reverse engineering in vitro model systems that recreate the structure and function of native tissue for applications ranging from high-throughput drug testing to regenerative medicine.
While reverse engineering native tissues and organs has important implications in biomedical engineering, the ability to “build with biology” presents the next generation of engineers with both a unique design challenge and opportunity. Specifically, we now have the ability to forward engineer bio-hybrid machines and robots (bio-bots) that harness the adaptive functionalities of biological materials to achieve more complex functional behaviors than machines composed of synthetic materials alone. Perhaps the most intuitive demonstration of a “living machine” is a system that can generate force and produce motion. To that end, we have designed and 3D printed locomotive bio-bots, powered by external electrical and optical stimuli. In addition to being the first demonstrations of untethered locomotion in skeletal musclepowered soft robots, these bio-hybrid machines have served as meso-scale models for studying tissue self-assembly, maturation, damage, remodeling, and healing in vitro.
Bio-hybrid machines that can dynamically sense and adaptively respond to a range of environmental signals have broad applicability in healthcare applications such as dynamic implants or targeted drug delivery. Advanced research in exoskeletons and hyper-natural functionality could even extend the useful application of such machines to national defense and environmental cleanup. We have developed a modular skeletal muscle bioactuator that can serve as a fundamental building block for such machines, setting the stage for future generations of bio-hybrid machines that can self-assemble, self-heal, and perhaps even self-replicate to target grand engineering challenges. Furthermore, we present a robust optimized protocol for manufacturing 3D printed muscle-powered biological machines, and a mechanism to incorporate biological “building blocks” into the toolbox of the next generation of engineers and scientists.The student, Ritu Raman, accepted the attached license on 2016-11-03 at 08:49.The student, Ritu Raman, submitted this Dissertation for approval on 2016-11-03 at 08:56.This Dissertation was approved for publication on 2016-11-04 at 16:03.DSpace SAF Submission Ingestion Package generated from Vireo submission #10217 on 2018-08-14 at 15:59:50Made available in DSpace on 2018-08-14T21:37:10Z (GMT). No. of bitstreams: 9
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Previous issue date: 2016-11-04Embargo set by: Seth Robbins for item 106495
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Correction: MLKL promotes cellular differentiation in myeloid leukemia by facilitating the release of G-CSF (Cell Death & Differentiation, (2021), 10.1038/s41418-021-00811-1).
No full textThe original version of this article unfortunately contained a mistake in an author name. Dr. Ritu Mishra was misspelled as “Misra”. The authors apologize for the mistake. The original article has been corrected
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