1,308 research outputs found
sj-docx-1-dhj-10.1177_20552076221140763 - Supplemental material for Access, charge and quality of tele-dermatology e-consults in China: A standardized patients study
No full textSupplemental material, sj-docx-1-dhj-10.1177_20552076221140763 for Access, charge and quality of tele-dermatology e-consults in China: A standardized patients study by Rui Guo, Mengchi Hou, Yangyang Han and Xing Lin Feng in Digital Health</p
19-0406_supplementary_materials – Supplemental material for Association Between Extent of Stent-Graft Coverage and Thoracic Aortic Remodeling After Endovascular Repair of Type B Aortic Dissection
No full textSupplemental material, 19-0406_supplementary_materials for Association Between Extent of Stent-Graft Coverage and Thoracic Aortic Remodeling After Endovascular Repair of Type B Aortic Dissection by Yan Xue, Yangyang Ge, Xiaohu Ge, Jianhang Miao, Weidong Fan, Dan Rong, Feng Liu, Xiaoping Liu and Wei Guo in Journal of Endovascular Therapy</p
sj-docx-1-aim-10.1177_09645284221085278 – Supplemental material for Manual acupuncture at ST36 attenuates rheumatoid arthritis by inhibiting M1 macrophage polarization and enhancing Treg cell populations in adjuvant-induced arthritic rats
No full textSupplemental material, sj-docx-1-aim-10.1177_09645284221085278 for Manual acupuncture at ST36 attenuates rheumatoid arthritis by inhibiting M1 macrophage polarization and enhancing Treg cell populations in adjuvant-induced arthritic rats by Nannan Yu, Fuming Yang, Xue Zhao, Yongming Guo, Yuan Xu, Guangchang Pang, Yinan Gong, Shenjun Wang, Yangyang Liu, Yuxin Fang, Kun Yu, Lin Yao, Hui Wang, Kuo Zhang, Baohu Liu, Zhenguo Wang, Yi Guo and Zhifang Xu in Acupuncture in Medicine</p
Interleukin-1 mediated cell-type specific signaling in hippocampal neurons and astrocytes
No full textInterleukin-1β (IL-1β) is a pro-inflammatory cytokine that is implicated in immune and inflammatory responses. In the central nervous system (CNS), IL-1β is synthesized and released during injury, infection, and many neurodegenerative diseases, but also under physiological conditions. Several IL-1-mediated signaling pathways and effects have been identified in hippocampal neurons and astrocytes, but their mechanisms have not been fully defined. IL-1 signaling requires the type one IL-1 receptor (IL-1RI) as well as IL-1 receptor accessory protein (IL-1RAcP) as a receptor partner. A novel isoform of the IL-1 receptor accessory protein, AcPb, has also been found in the CNS, but its role remains unclear. This thesis examined AcPb function in regulating IL-1β signaling. The results showed that IL-1β activated p38 MAPK but not NFκB in neurons. In astrocytes, IL-1β induced both p38 and NFκB pathways in regulating inflammatory responses. AcPb was not involved in mediating either p38 or NFκB in either cell type. In contrast, a physiological level of IL-1β treatment (0.01ng/ml) activated p-Src in neurons via AcPb in vitro. In addition, overexpression of AcPb in astrocytes was sufficient to induce p-Src mediated by IL-1β. Taken together, these results suggest that the restricted expression of AcPb in CNS neurons may mediate neuronal specific IL-1 pathways and outcomes, and that physiological and pathophysiological levels of IL-1β mediate particular neuronal functions via separate pathways.Ph. D.Includes abstractIncludes bibliographical referencesby Yangyang Huan
Supplemental Material—Short- and Long-term Outcomes of the Minimal Proximal Resection Margin in Total Gastrectomy for Siewert II Adenocarcinoma of the Esophagogastric Junction
No full textSupplemental Material for Short- and Long-term Outcomes of the Minimal Proximal Resection Margin in Total Gastrectomy for Siewert II Adenocarcinoma of the Esophagogastric Junction by Wei Guo, PhD, Jinguo Hao, MD, Xianghuang Mei, PhD, Yangyang Wang, MD, Zhipeng He, MD, Shi Su, MD, Ke Zhang, MD, Xiaoqi Guan, MD, Jingcheng Yang, MD, and Jiake Lv, MD in The American Surgeon.</p
sj-docx-1-taj-10.1177_20406223221109651 – Supplemental material for Sarcopenia and frailty combined increases the risk of mortality in patients with decompensated cirrhosis
No full textSupplemental material, sj-docx-1-taj-10.1177_20406223221109651 for Sarcopenia and frailty combined increases the risk of mortality in patients with decompensated cirrhosis by Gaoyue Guo, Chaoqun Li, Yangyang Hui, Lihong Mao, Mingyu Sun, Yifan Li, Wanting Yang, Xiaoyu Wang, Zihan Yu, Xiaofei Fan, Kui Jiang and Chao Sun in Therapeutic Advances in Chronic Disease</p
Metamorphism and fluid evolution of the Sumdo eclogite, Tibet: Constraints from mineral chemistry, fluid inclusions and oxygen isotopes
No full textMolecular simulations of rheological, mechanical and transport properties of solid-fluid systems:
No full textIn this dissertation, two distinct but relevant systems are chosen as representatives of interesting solid-fluid systems. Molecular dynamics (MD) and Monte Carlo techniques are applied to investigate the rheological, mechanical and transport properties of these systems.
Firstly, polyethylene melt embedded with silica nanoparticles is examined to be of our interest. Since it is computationally impractical to model a complex system with a molecular description, a multiscale modeling approach, which combines both atomistic and mesoscale simulations, is employed to efficiently represent and study the polymer nanoparticle systems. Based on a coarse-grained force field for polyethylene, a novel method is developed for determining the solid-fluid interaction at the spherical interface. Our coarse grained model is designed to mimic 4 nm silica nanoparticles in polyethylene melt at 423K. A series of MD simulations are performed to investigate the factors that control the homogeneity of nanofillers inside polymer matrix, also in the presence of nonionic surfactants (short chain alcohols). The effects of nanoparticle filling fraction, polymer chain length, and relative sizes between nanoparticles and polymer chains on the particle dispersion are explored. In addition, a fundamental relationship is pursued between the microstructure and macroscopic properties (transport and rheological) of polymer nanoparticle composites.
In this work another method for determining the solid-fluid interaction parameter is presented: the experimental adsorption isotherms are used to validate the potential parameters. The rapid expansion of silica nanoparticle agglomerates in supercritical carbon dioxide (RESS process) is chosen to be the system of interest. The simulations show that the effective attraction between two identical nanoparticles is most prominent for densely hydroxylated particle surfaces that interact strongly with CO2 via hydrogen bonds, while it is significantly weaker for dehydroxylated particles. We also explore the shearing forces necessary to break an agglomerate in supercritical fluid. The agglomerate experiences deformation followed by elongation, and finally break-up. The calculated diffusion coefficient of CO2 is expected to be smaller than the experimental value, because the nanoparticle agglomerate hinders fluid movement. In the direction of shearing forces, the diffusion of CO2 shows a steep increase after the breakup, confirming the rupture of the agglomerate.Ph.D.Includes bibliographical references (p. 136-142)by Yangyang She
sj-docx-3-tam-10.1177_17588359211054895 – Supplemental material for Comprehensive analysis of prognostic value of lymph node classifications in esophageal squamous cell carcinoma: a large real-world multicenter study
No full textSupplemental material, sj-docx-3-tam-10.1177_17588359211054895 for Comprehensive analysis of prognostic value of lymph node classifications in esophageal squamous cell carcinoma: a large real-world multicenter study by Junmiao Wen, Jiayan Chen, Donglai Chen, Salma K. Jabbour, Tao Xue, Xufeng Guo, Haitao Ma, Fei Ye, Yiming Mao, Jian Shu, Yangyang Liu, Xueguan Lu, Zhen Zhang, Yongbing Chen and Min Fan in Therapeutic Advances in Medical Oncology</p
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