38,973 research outputs found
Design spectra to be used in Base Isolation Design in light of recent strong motion records
Strong motion records have shown an increase of the maximum values of PGA and PGV, also associated to the increase of the archived strong motion records. Nowadays, the worldwide largest PGA values are: 3,94g (vertical) and 2,75g (horizontal), from the 2008 Iwate-Miyagi and 2011 Tohoku earthquakes, while the current PGV maxima are larger than 2.0 m/s (horizontal and vertical). These unforeseen values have encouraged a more conscious approach in BIS design, being necessary to move to larger design periods and to face wider design displacements. Many changes have occurred in the history of BIS, as indicated in Design Recommendations for Seismically Isolated Buildings by AIJ (2016), tracing the improvements of BIS in Japan, and in De Luca and Guidi (2019). In this excursion, a significant contribution has been given by Miyazaki (2008) that defined a "Next Generation of seismic isolation" to counteract the unprecedented spectral values of displacement and acceleration. In this perspective, the paper analyzes the acceleration, velocity and displacement spectra of different sets of strong motion records to provide suggestions for seismic design of base-isolated structures in the light of higher spectral values. In particular, we will consider: the set defined in Trevor Kelly (2001), that divided motions into pre-1971 and post-1971; the set of FEMA307 (1999), in which three categories of ground motion are considered (short duration, long duration and forward directivity); the set used by Miyazaki (2008) for the Next Generation of Seismic Isolation; the set defined by Suzuki and Iervolino (2017) to trace the history of largest PGA and PGV; the set used by De Luca and Guidi (2019) to trace the improvements in BIS design and propose a classification of BIS in three successive generations. A comparison between results, for different periods, will lead to possible design indications for BIS
Influence of the needle bore size on platelet count and routine coagulation testing.
The phlebotomy technique, particularly the use of small-bore needles, may influence the reliability of coagulation testing and platelet count. Routine coagulation tests were assayed in blood specimens collected from 22 consecutive patients in three separate, sequential phlebotomies, using butterfly devices with different needle sizes. Test results of samples collected with 23 and 25 G needles were compared with those obtained with the currently recommended 21 G needle. Although both the prothrombin time and activated partial thromboplastin time displayed a trend towards lower values employing the smaller 23 and 25 G needles, results did not differ significantly from the reference 21 G needle specimen, with the exceptions of D-dimer (25 G versus 21 G needle, 186 ± 70 versus 178 ± 66/ml, P < 0.01) and platelet count (23 G versus 21 G needle, 246 ± 55 versus 254 ± 56 × 10/l, P < 0.01; 25 G versus 21 G needle, 240 ± 55 versus 254 ± 56 × 10/l, P < 0.01). None of the mean biases recorded for the parameters was clinically meaningful, nor did they exceed the current desirable analytical quality specifications for desirable bias. Results of the present investigation suggest that, when a proper technique is used and within certain limitations, butterfly devices with small-bore needles may be a reliable alternative to draw venous blood for platelet count and coagulation testing. © 2006 Lippincott Williams & Wilkins
Influence of stable, long-term treatment with phenobarbital on the activity of serum alanine aminotransferase and gamma-glutamyltransferase
Phenobarbital, a long-acting barbiturate, is generally considered to be a fairly safe and effective drug; however, hepatotoxicity is an infrequent but potentially fatal adverse effect and there is little information on the serum activity of liver enzymes in patients on stable, long-term monotherapy. The serum activity of alanine aminotransferase (ALT) and γ-glutamyltransferase (GGT) are measured along with phenobarbital as part of the routine biochemical measurement in 128 consecutive adult out-patients on stable, long-term phenobarbital treatment. The control population consists of 2468 consecutive out-patients matched for age and gender. The patients on long-term phenobarbital therapy had significantly higher serum acitivities of ALT (27 IU/L versus 23 IU/L, P<0.001) and GGT (79% IU/L versus 24 IU/L, P<0.001). The prevalence of subjects with abnormal GGT values, but not ALT, was signifacantly higher than that in the control population. No significant difference were observed in either the mean activity or the prevalence of abnormal values of ALT or GGT between patients with suboptimal and therapeutic concentrations of the drug. These results suggest that chronic phenobarbital therapy may be associated with a clinically significant elevation of serum GGT activity. If confirmed, a specific GGT reference range should be adopted. Moreover, in those patients presenting with high serum GGT activity, it would not be necessary to reduce the dosage, discontinue the drug or change to a different anti-epileptic medication
Geophysical prospections with GPR RIS/MF system. A preliminary Archaeological Survey of the Erbil Citadel
Il volume Preservation of Cultural Heritage of the Kurdish Region in Iraq presenta i principali risultati del primo biennio (2009-2010) di lavori della Missione Archeologica Italiana nel Kurdistan iracheno, codiretta da Carlo G. Cereti e Roberta Giunta.
Il progetto (Italian Cooperation Project in Iraqi Kurdistan), nato grazie all’appoggio della Direzione Generale per la Cooperazione allo Sviluppo della Repubblica Italiana, rappresenta un importante passaggio nella collaborazione, iniziata nel 2006, tra il Kurdistan Iracheno e l’IsIAO (Istituto per l’Africa e l’Oriente, Roma).
Il presente volume rappresenta una prima sintesi, di grande spessore, delle ricerche ad ampio raggio intraprese dalla Missione nella capitale del Kurdistan, Erbil, e nel territorio, finalizzate alla conoscenza, al restauro e alla valorizzazione del patrimonio archeologico, storico e monumentale del Kurdistan iracheno.
Riedizione digitale del volume pubblicato nell’aprile 2011 da IsIAO (Roma).The book Preservation of Cultural Heritage of the Kurdish Region in Iraq presents the main results of the first two years (2009-2010) of activity of the Italian Archaeological Mission in Iraqi Kurdistan, co-directed by Carlo G. Cereti and Roberta Giunta.
The project (Italian Cooperation Project in Iraqi Kurdistan), thanks to the support of the Italian Direzione Generale per la Cooperazione allo Sviluppo, is an important step in the collaboration, begun in 2006, between Iraqi Kurdistan and IsIAO (Italian Institute for Africa and the East, Rome).
This volume represents a first interim report of the wide-range researches undertaken by the Mission in the Capital of Kurdistan, Erbil, and in its territory, aimed at a better knowledge, preservation and enhancement of the archaeological, historical and monumental heritage of Iraqi Kurdistan.
Digital edition of the book published in April 2011 by IsIAO (Rome)
Giulio Schmiedt, Il livello antico del Mar Tirreno. Testimonianze dei resti archeologici, con la collaborazione di M. Caputo, G. Conta, F. Guidi, M. Pellegrini, L. Pieri
Van Wonterghem Frank. Giulio Schmiedt, Il livello antico del Mar Tirreno. Testimonianze dei resti archeologici, con la collaborazione di M. Caputo, G. Conta, F. Guidi, M. Pellegrini, L. Pieri. In: L'antiquité classique, Tome 43, fasc. 1, 1974. pp. 660-662
Possible transovarial transmission of symbiotic bacteria in Reticulitermes lucifugus (ISOPTERA: RHINOTERMITIDAE)Ins Soc Life
Symbiotic bacteria have been found in cytoplasm and in nucleus of the oocytes from all developmental stages and trophocytes of periovarial fat bodies of supplementary reproductives and nymphs of Reticulitemles lucifugus (Isoptera: Rhinotermitidae). The bacteria resemble intracellular symbionts found in other insect species. The presence of bacteria in the gut lumen of fully developed embryos and "pharate" larvae suggest a transovarial transmission of intracellular symbionts (endocytobionts) in R. lucifugus. This transovarial transmission does not appear to be correlated with presence and differentiation of specialized cells such as bacteriocyte
Batteri simbionti endonucleari in Kalotermes flavicollis e Reticulitermes lucifugus ( Isoptera)”.
Design of digital interaction for complex museum collections
Interactive multimedia applications in museums generally aim at integrating into the exhibition complementary information delivered through engaging narratives. This article discusses a possible approach for effectively designing an interactive app for museum collections whose physical pieces are mutually related by multiple and articulated logical interconnections referring to elements of immaterial cultural heritage that would not be easy to bring to the public with traditional means. As proof of this concept, a specific case related to ancient Egyptian civilization has been developed. A collection of Egyptian artifacts such as mummies, coffins, and amulets, associated with symbols, divinities, and magic spells through the structured funerary ritual typical of that civilization, has been explained through a virtual application based on the concepts discussed in the methodological section
Massive 3D Digitization of Museum Contents
The goal of the 3D-ICONS European Project is to provide EUROPEANA ( www.europeana.eu ) with accurate 3D models of architectural and archaeological monuments and buildings of remarkable cultural importance. The purpose of this paper is to describe the specific processing pipeline that has been set for digitizing a significant part of the Civic Archaeological Museum in Milan (Italy). All the technical and logistic aspects needed for capturing 3D models in a Museum environment, the implication with IPR, and the metadata acquisition, are covered. The main issue is generating a good result by the technical point of view, minimizing the impact on the usual Museum activity during the 3D capturing operations, shortening in the meantime the processing time to the minimal allowed by the different applicable techniques. This condition has led different choices related to the survey technologies (laser scanning and image based modeling) and the related data processing. Both technical and descriptive metadata have been collected for each item acquired, for generating a record of data searchable on EUROPEANA, with the addition of new metadata not defined in the minimal record, for making traceable the path leading to the generated digital content. The paper gives a general discussion of such issues with some specific examples referred to the large set of 3D objects digitized within the 3D-ICONS project
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