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Surgical Rhinoplasty After Hyaluronic Acid Injection: What Are the Implications? Our Experience
No full textDelayed hemolytic transfusion reaction due to anti-S antibody in patient with anti-Jk(a) autoantibody and multiple alloantibodies.
No full textWe describe the case of a 60-year-old woman
with a delayed hemolytic transfusion reaction (DHTR).
She had a history of an ulcerative colitis, blood transfusion
because of rectal bleeding, and surgical removal of
descendent and sigmoid colon. At admission, laboratory
data showed Hb 6.3 g/dL, reticulocytes 120*109/L, serum
total bilirubin 1.2 mg/dL (direct bilirubin: 0.2 mg/dL).
Pretransfusion antibody screening procedures were positive.
A monospecific autoanti-Jka and three alloantibodies
(anti-c, -E, -K) were identified by immunohematologic
studies. The patient received two units of crossmatch
compatible concentrated red blood cells. Six days later
biochemical serum values showed Hb 6.2 g/dL, LDH
975 I.U./L and total bilirubin 2.95 mg/dL (direct 0.35 mg/
dL). Crossmatches with red cell suspension of transfused
blood units and a post-transfusion serum were repeatedly
positive. Laboratory tests showed the presence of anti-S
alloantobody in the serum and eluate. Moreover, pretransfusion
serum of the patient was retrospectively
retested: anti-S was not detected. These data suggested
a DHTR. The present case is unusual and interesting
because of the association of a rare autoanti-Jka, non
responsible for anemia, and four alloantibodies of which
anti-S involved in a DHTR
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