1,733 research outputs found

    Lettera di Alessandra

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    Un ritratto critico dell'opera di Alessandra Carnaroli, autrice fra le più apprezzate delle ultime generazioni della poesia di ricerca. La sezione a lei dedicata, nel numero della rivista, contiene inoltre saggi di Cecilia Bello Minciacchi, Andrea Cortellessa, e Ivan Schiavone; e vari inediti dell'autrice. Il saggio è pubblicato con lo pseudonimo di Tommaso Ottonieri.A critical portrait of the work of Alessandra Carnaroli, author of the most appreciated in the latest generations of italian research poetry. Published under the pseudonym Tommaso Ottonieri

    Selected letters of Alessandra Strozzi

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    The letters of Alessandra Strozzi provide a vivid and spirited portrayal of life in fifteenth-century Florence. Among the richest autobiographical materials to survive from the Italian Renaissance, the letters reveal a woman who fought stubbornly to preserve her family's property and position in adverse circumstances, and who was an acute observer of Medicean society. Her letters speak of political and social status, of the concept of honor, and of the harshness of life, including the plague and the loss of children. They are also a guide to Alessandra's inner life over a period of twenty-three years, revealing the pain and sorrow, and, more rarely, the joy and triumph, with which she responded to the events unfolding around her.This edition includes translations, in full or in part, of 35 of the 73 extant letters. The selections carry forward the story of Alessandra's life and illustrate the range of attitudes, concerns, and activities which were characteristic of their author

    Challenging the author: Gavin Douglas's Eneados

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    Gavin Douglas’s Eneados, a translation into the “Scottis” tongue of Virgil’s Aeneid, completed in 1513 and first published in London in 1553, presents, as well as the translation of the additional thirteenth book by Maphaeus Vegius, original prologues and marginal notes to the text, rubrics and articulate conclusive material. The present paper analyses this complex paratext as evidence of Douglas’s almost philological attention to the original and his preoccupation with a faithful reproduction; it is also suggested that the models for his organization of the commentary might be both medieval (i.e., manuscripts such as Petrarch’s Virgilius Ambrosianus) and early modern, as in the case of editions of classical works: the most apt example being Jodocus Badius Ascensius’ edition of the Aeneid, printed in 1501. The Eneados thus stands on the threshold between manuscript and print, and might have indicated new possibilities of use of the printing medium in Scotland, and of the value of the translation of a classical text, had history not intervened with the Scottish defeat at Flodden Fields in 1513, which put a temporary stop both to the circulation of the Eneados and to the development of Scottish printing

    Nicetas Nicaenus, De azymis

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    The RAP online repertorium offers the first comprehensive catalogue of polemical literature related to the schism between the Roman Catholic and Orthodox Churches from the 9th to the 16th century and can be described as an ideal continuation of the *Clavis Patrum*. Each entry identifies the work (often unpublished or newly discovered in manuscript catalogs), lists its various titles (since medieval texts often lack stable titles), provides incipit and explicit (with possible variations), and examines the manuscript tradition and foliation (by reviewing catalogs or manuscripts, verifying dates, folios, etc.). It also includes relevant bibliography (critical editions and studies), identifies the author (using prosopographical studies, dictionaries, repertories, sigillography, etc.), and provides essential biographical details. Each work is classified by literary genre (e.g., treatise, dialogue), the corresponding Byzantine term, and the main polemical themes (e.g., Filioque, Azymes, Purgatory), and is assigned a unique RAP identification number. The Repertorium Auctorum Polemicorum is identified by the International Standard Serial Number (ISSN) 3035-2096 [continuously updated publication

    Polemica scripta anonyma, Dialogus inter Graecum et Cardinales quosdam de processione Spiritus Sancti

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    The RAP online repertorium offers the first comprehensive catalogue of polemical literature related to the schism between the Roman Catholic and Orthodox Churches from the 9th to the 16th century and can be described as an ideal continuation of the *Clavis Patrum*. Each entry identifies the work (often unpublished or newly discovered in manuscript catalogs), lists its various titles (since medieval texts often lack stable titles), provides incipit and explicit (with possible variations), and examines the manuscript tradition and foliation (by reviewing catalogs or manuscripts, verifying dates, folios, etc.). It also includes relevant bibliography (critical editions and studies), identifies the author (using prosopographical studies, dictionaries, repertories, sigillography, etc.), and provides essential biographical details. Each work is classified by literary genre (e.g., treatise, dialogue), the corresponding Byzantine term, and the main polemical themes (e.g., Filioque, Azymes, Purgatory), and is assigned a unique RAP identification number. The Repertorium Auctorum Polemicorum is identified by the International Standard Serial Number (ISSN) 3035-2096 [continuously updated publication

    Theophylactus Bulgariae archiepiscopus, Allocutio ad quemdam ex suis familiaribus de iis quorum Latini incusantur

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    The RAP online repertorium offers the first comprehensive catalogue of polemical literature related to the schism between the Roman Catholic and Orthodox Churches from the 9th to the 16th century and can be described as an ideal continuation of the *Clavis Patrum*. Each entry identifies the work (often unpublished or newly discovered in manuscript catalogs), lists its various titles (since medieval texts often lack stable titles), provides incipit and explicit (with possible variations), and examines the manuscript tradition and foliation (by reviewing catalogs or manuscripts, verifying dates, folios, etc.). It also includes relevant bibliography (critical editions and studies), identifies the author (using prosopographical studies, dictionaries, repertories, sigillography, etc.), and provides essential biographical details. Each work is classified by literary genre (e.g., treatise, dialogue), the corresponding Byzantine term, and the main polemical themes (e.g., Filioque, Azymes, Purgatory), and is assigned a unique RAP identification number. The Repertorium Auctorum Polemicorum is identified by the International Standard Serial Number (ISSN) 3035-2096 [continuously updated publication

    Can brain network connectivity facilitate the clinical development of disease-modifying anti-Alzheimer drugs?

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    The preclinical phase of Alzheimer's disease represents a crucial time window for therapeutic intervention but requires the identification of clinically relevant biomarkers that are sensitive to the effects of disease-modifying drugs. Amyloid peptide and tau proteins, the main histological hallmarks of Alzheimer's disease, have been widely used as biomarkers of anti-amyloid and anti-tau drugs. However, these biomarkers do not fully capture the multiple biological pathways of the brain. Indeed, robust amyloid-target engagement by anti-amyloid monoclonal antibodies has recently translated into modest cognitive and clinical benefits in Alzheimer's disease patients, albeit with potentially life-threatening side effects. Moreover, targeting the tau pathway has yet to result in any positive clinical outcomes. Findings from computational neuroscience have demonstrated that brain regions do not work in isolation but are interconnected within complex network structures. Brain connectivity studies suggest that misfolded proteins can spread through these connections, leading to the hypothesis that Alzheimer's disease is a pathology of network disconnectivity. Based on these assumptions, here we discuss how incorporating brain connectivity outcomes could better capture global brain functionality and, in conjunction with traditional Alzheimer's disease biomarkers, could facilitate the clinical development of new disease-modifying anti-Alzheimer's disease drugs.Pin et al. propose a new paradigm in the field of pharmacological research for Alzheimer's disease. According to this new perspective, brain connectivity could play a key role in the search for pharmacological targets, in patient selection for clinical trials, and finally, as an efficacy marker to evaluate pharmaceutical compounds

    Polemica scripta anonyma, Contra unionem ecclesiarum

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    The RAP online repertorium offers the first comprehensive catalogue of polemical literature related to the schism between the Roman Catholic and Orthodox Churches from the 9th to the 16th century and can be described as an ideal continuation of the *Clavis Patrum*. Each entry identifies the work (often unpublished or newly discovered in manuscript catalogs), lists its various titles (since medieval texts often lack stable titles), provides incipit and explicit (with possible variations), and examines the manuscript tradition and foliation (by reviewing catalogs or manuscripts, verifying dates, folios, etc.). It also includes relevant bibliography (critical editions and studies), identifies the author (using prosopographical studies, dictionaries, repertories, sigillography, etc.), and provides essential biographical details. Each work is classified by literary genre (e.g., treatise, dialogue), the corresponding Byzantine term, and the main polemical themes (e.g., Filioque, Azymes, Purgatory), and is assigned a unique RAP identification number. The Repertorium Auctorum Polemicorum is identified by the International Standard Serial Number (ISSN) 3035-2096 [continuously updated publication

    Petrus Antiochenus ptr. III, Epistulae de schisma

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    www.unive.it/rap The RAP online repertorium offers the first comprehensive catalogue of polemical literature related to the schism between the Roman Catholic and Orthodox Churches from the 9th to the 16th century and can be described as an ideal continuation of the *Clavis Patrum*. Each entry identifies the work (often unpublished or newly discovered in manuscript catalogs), lists its various titles (since medieval texts often lack stable titles), provides incipit and explicit (with possible variations), and examines the manuscript tradition and foliation (by reviewing catalogs or manuscripts, verifying dates, folios, etc.). It also includes relevant bibliography (critical editions and studies), identifies the author (using prosopographical studies, dictionaries, repertories, sigillography, etc.), and provides essential biographical details. Each work is classified by literary genre (e.g., treatise, dialogue), the corresponding Byzantine term, and the main polemical themes (e.g., Filioque, Azymes, Purgatory), and is assigned a unique RAP identification number. The Repertorium Auctorum Polemicorum is identified by the International Standard Serial Number (ISSN) 3035-2096 [continuously updated publication

    Hadrianus papa IV, Ep. ad Basilium Achridenum

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    www.unive.it/rap The RAP online repertorium offers the first comprehensive catalogue of polemical literature related to the schism between the Roman Catholic and Orthodox Churches from the 9th to the 16th century and can be described as an ideal continuation of the *Clavis Patrum*. Each entry identifies the work (often unpublished or newly discovered in manuscript catalogs), lists its various titles (since medieval texts often lack stable titles), provides incipit and explicit (with possible variations), and examines the manuscript tradition and foliation (by reviewing catalogs or manuscripts, verifying dates, folios, etc.). It also includes relevant bibliography (critical editions and studies), identifies the author (using prosopographical studies, dictionaries, repertories, sigillography, etc.), and provides essential biographical details. Each work is classified by literary genre (e.g., treatise, dialogue), the corresponding Byzantine term, and the main polemical themes (e.g., Filioque, Azymes, Purgatory), and is assigned a unique RAP identification number. The Repertorium Auctorum Polemicorum is identified by the International Standard Serial Number (ISSN) 3035-2096 [continuously updated publication
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