2,343 research outputs found
Gerald Gregory MacDonald
No full textposted: SaltWire, Jun. 10, 2021; funeral arrangements by C. L. Curry Funeral Services; "Greg"
Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols
No full textEfforts to improve the production of a compound of interest in Saccharomyces cerevisiae have mainly involved engineering or overexpression of cytoplasmic enzymes. We show that targeting metabolic pathways to mitochondria can increase production compared with overexpression of the enzymes involved in the same pathways in the cytoplasm. Compartmentalization of the Ehrlich pathway into mitochondria increased isobutanol production by 260%, whereas overexpression of the same pathway in the cytoplasm only improved yields by 10%, compared with a strain overproducing enzymes involved in only the first three steps of the biosynthetic pathway. Subcellular fractionation of engineered strains revealed that targeting the enzymes of the Ehrlich pathway to the mitochondria achieves greater local enzyme concentrations. Other benefits of compartmentalization may include increased availability of intermediates, removing the need to transport intermediates out of the mitochondrion and reducing the loss of intermediates to competing pathways.National Institutes of Health (U.S.). Ruth L. Kirschstein National Research Service Award (1F32GM098022-01A1)National Institutes of Health (U.S.) (Grant GM040266)Shell Global Solutions (US
Photo 119
No full textArrival of Dick Gregory at Portland airport. l-r Gerald Talbot, Rachel Talbot, Dick Gregory, Sonny Cummings, Renee Talbot, Gary Merrilhttps://digitalcommons.usm.maine.edu/talbot_adciv/1000/thumbnail.jp
A.P. Marshall Collection Black History 1
No full textMembers of the Co. B 102nd USCT Black History Group l to r Billy Potts, Gerald Moss, Gregory Miles Sr., Bruce Clark, Ross Fowler, John Hall, Don Vest and drummer Gregory Miles Jr
The perceptions of faculty and student affairs practitioners on the challenges for internationalization at a historically Black university in the southeastern United States, 2020
No full textThis descriptive mixed-methods case study of faculty and student affairs practitioners' perceptions determined challenges to internationalization at a historically black university in the Southeastern United States by examining challenges affecting international students, on-campus internationalization preparation, differentiated instruction for international students, the office of international student affairs staff support, international student advisement, and global sensitivity training. Fifteen participants (11 faculty and 4 student affairs practitioners) were surveyed and a semistructured interview was conducted with a student affairs practitioner employed by the institution. The data collected revealed findings, implications, and recommendations that suggested further research for faculty, student affairs practitioners, and the institution. The major findings of this study indicated five relevant themes that emerged through the surveys and interview: institutional preparedness, institutional awareness, institutional resources, communication, and institutional response. These major findings were found to be the perceived challenges to internationalization at the institution. Limitations of this study included (a) self-reported data that may not be an exact representation; (b) solely one institution included in the research; (c) low participation rate; (d) international students primarily from Saudi Arabia; and (e) the researcher used a convenience sample. The study revealed that further research in the areas of institutional preparation and institutional training for faculty and student affairs practitioners/staff would be beneficial
The reception of Qoheleth in a selection of rabbinic, patristic and nonconformist texts
No full textThe purpose of this thesis is to examine the reception of the text of Qoheleth in a selection of rabbinic, patristic and nonconformist literature. The differences in the act of reading, reception and response to this text in discrete
Judaic and Christian locations is examined. The source texts that are considered are Qoheleth Rabbah, Targum Qoheleth, Gregory of Nyssa's homilies and Matthew Henry's exposition on Ecclesiastes. The thesis further investigates historical and theological experiential influences on the reception of Qoheleth as portrayed by the source texts. The text of Qoheleth and its history of interpretation, and the value of
examining the reception of the text by specific readers from a variety of contexts are discussed in the first chapter. In the consecutive chapters the reception of Qoheleth by each source text is examined individually. The historical and
theological contexts of each source text are described, including literary traditions and exegetical principles.
In the detailed examination of the source texts, the textual structural challenges that Qoheleth poses and how and why
they are responded to by the author(s) of the source texts are analysed. The final chapter compares and contrasts the main issues raised by the differing readings of Qoheleth, including the identity of Solomon and the view of God, and also, the differing contextual perspectives in which the reception process took place. Finally, a brief examination of a modem reader's (Michael V Fox') reception of Qoheleth is contrasted with that of earlier readers of the text. The manner in which the potential effects of Qoheleth are actualised and the process of meaning production varies between readers, being conditioned by their historical horizon
Craterocephalus stramineus
No full textCraterocephalus stramineus (Whitley) Strawman, Blackmast The distribution of Craterocephalus stramineus is confined to the Gregory River of Queensland, the Katherine, Finniss, Daly, and Victoria Rivers of the Northern Territory, and the Ord River in the Kimberley region (Fig. 17) (Allen et al. 2002). However, the outlying record of the species from the upper Fitzroy River in Allen and Leggett (1990) is actually from the Ord catchment; an incorrect co-ordinate is given in the paper that did not correspond to site location. This also applies for other species captured at the site including N. erebi, M. australis, A. percoides, L. unicolor and G. giuris (see Figs. 4, 18, 27, 32 and 40). Therefore, we consider the Kimberley distribution as being confined to the Ord River, where it is widespread and abundant.Published as part of Morgan, David L., Allen, Gerald R., Pusey, Bradley J. & Burrows, Damien W., 2011, 2816, pp. 1-64 in Zootaxa 2816 on page 1
A phaseguided passive batch microfluidic mixing chamber for isothermal amplification
No full textWith a view to developing a rapid pathogen detection system utilizing isothermal nucleic acid amplification, the necessary micro-mixing step is innovatively implemented on a chip. Passive laminar flow mixing of two 6.5 mu l batches differing in viscosity is performed within a microfluidic chamber. This is achieved with a novel chip space-saving phaseguide design which allows, for the first time, the complete integration of a passive mixing structure into a target chamber. Sequential filling of batches prior to mixing is demonstrated. Simulation predicts a reduction of diffusive mixing time from hours down to one minute. A simple and low-cost fabrication method is used which combines dry film resist technology and direct wafer bonding. Finally, an isothermal nucleic acid detection assay is successfully implemented where fluorescence results are measured directly from the chip after a one minute mixing sequence. In combination with our previous work, this opens up the way towards a fully integrated pathogen detection system in a lab-on-a-chip format
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