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    Obstructive sleep apnoea syndrome: What the anesthesiologist should know

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    Obstructive sleep apnoea syndrome (OSAS) is a rather common sleep disorder and constitutes a risk or an aggravating factor for various underlying diseases. OSAS is characterised by repeated upper airway collapse during sleep causing fragmented sleep, hypoxemia and hypercapnia. It may also cause considerable changes in intrathoracic pressure and an increase in sympathetic nervous activity, which represent the basis of associated pathologies such as arterial hypertension, ischaemic heart disease, diabetes mellitus, stroke and sudden death [1]. Moreover, there is a wellestablished association between OSAS and postoperative complications [2, 3]. Nevertheless, a significant proportion of patients affected by OSAS undergo surgery without diagnosis and, consequently, without therapy [4]. Therefore, it is crucial for the anaesthesiologist to identify patients at risk of OSAS before surgery for a correct definition of a perioperative strategy to reduce the risk of perioperative complication. This process should be done independently and regardless of whether the patient undergoes general or locoregional anaesthesia

    Physiopathological rationale of using high-flow nasal therapy in the acute and chronic setting: A narrative review

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    Chronic lung disease and admissions due to acute respiratory failure (ARF) are becoming increasingly common. Consequently, there is a growing focus on optimizing respiratory support, particularly non-invasive respiratory support, to manage these conditions. High flow nasal therapy (HFNT) is a noninvasive technique where humidified and heated gas is delivered through the nose to the airways via small dedicated nasal prongs at flows that are higher than the rates usually applied during conventional oxygen therapy. HFNT enables to deliver different inspired oxygen fractions ranging from 0.21 to 1. Despite having only recently become available, the use of HFNT in the adult population is quite widespread in several clinical settings. The respiratory effects of HNFT in patients with respiratory failure may be particularly relevant for clinicians. In this narrative review, we discuss the main pathophysiological mechanism and rationale for using HFNT in the acute and chronic setting
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