72,868 research outputs found

    Deed, 1892, D. P. Graham and John W. Robinson to James L. Calfee for tract of land in Wythe County, Virginia.

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    A deed (fragmented and incomplete) given by D. P. Graham and his wife, and John W. Robinson and wife to James L. Calfee covering a tract of land in Wythe County, Virginia

    Villes sous contr\uf4le: La militarisation de l\u27espace urbain

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    Checkpoints, drones, GPS, passeports biom\ue9triques, insectes cyborgs, puces RFID, d\ue9tecteurs de cibles, essaims de nanocapteurs, soldats-robots, barri\ue8res Jersey, dirigeables de surveillance, bombes \uab incapacitantes \ubb et arsenal \uab non l\ue9tal \ubb... Qu\u27ont en commun toutes ces \uab technologies \ubb qui, pour certaines, semblent relever de la science-fiction et qui, pour d\u27autres, impr\ue8gnent d\ue9j\ue0 notre quotidien de citadins ? Concoct\ue9es dans les laboratoires de l\u27arm\ue9e, elles sont les nouvelles armes de la guerre en cours, cette \uab guerre asym\ue9trique \ubb ou \uab permanente \ubb qui transforme les arm\ue9es occidentales en forces contre-insurrectionnelles high-tech et chacun d\u27entre nous en cible potentielle n\ue9cessitant d\u27\ueatre identifi\ue9e, pist\ue9e, surveill\ue9e, au nom de la pr\ue9vention d\u27une menace indistincte. Avec Isra\uebl comme laboratoire et la \uab guerre contre le terrorisme \ubb comme terrain d\u27application mondial, cette nouvelle forme de conflit touche de mani\ue8re tr\ue8s diff\ue9renci\ue9e les habitants du monde riche et ceux des territoires post- et n\ue9o-coloniaux. Elle se signale cependant par un trait commun \ue0 tous : ses champs de bataille ne sont plus les plaines ou les d\ue9serts, mais les principales agglom\ue9rations urbaines mondiales. Dans le sillage des travaux de Mike Davis, Naomi Klein ou Eyal Weizman, le livre de Stephen Graham nous donne les cl\ue9s pour comprendre les logiques profondes de cet emballement militaro-s\ue9curitaire globalis\ue9

    Graham, Idaho (D)

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    An uphill view of the remains of the Graham mill flanked by pine trees

    Rain-flagging of the Envisat altimeter

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    As the goals for altimetric measurements become ever more precise, there is concern about the reliable detection and discarding of rain contaminated data. A dual-frequency rain detection technique developed for the Ku- and C-band TOPEX altimeter, is adapted for the Ku- and S-band RA-2 altimeter on Envisat. Of particular concern is the selection of a suitable threshold to minimise the quantity of good data inadvertently discarded

    Two new tryptophan derivatives from the seed kernels of Entada rheedei: Effects on cell viability and HIV infectivity

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    Two new tryptophan derivatives, N-sulfonyl-L-tryptophan (tryptorheedei A) (1) and 3-(Nsulfonylindolyl)- D-lactic acid (tryptorheedei B) (2) together with the known 5-O-β-Dglucopyranosyl- 2-hydroxyphenylacetic acid (3), 1-O-methylglucopyranoside, entadamide A, homogentisic acid and 3-O-β-D-glucopyranosyl-β-sitosterol, were isolated from the seed kernels of Entada rheedei (Mimosaceae). Their structures were established using 1D and 2D NMR spectroscopy, mass spectrometry and by comparison with spectroscopic data reported in the literature. Compounds 1 and 2 showed no toxicity to TZM and Human PBMC cells. Both compounds 1 and 2 were found to promote early infection events in HIV, likely by inhibiting the enzyme indolamine 2,3-dioxygenase (IDO) and preventing tryptophan depletion. Inhibition of IDO acutely in HIV infection inhibits viral replication, but chronic activation of IDO leads to immune impairment in AIDS. IDO is also the gatekeeper enzyme for kynurenine metabolism, a pathway involved in serotonin and melatonin biosynthesis and the regulation of glutamate and dopamine levels in the brain. Therefore inhibition of IDO might explain both the reported medicinal and neuropsychiatric effects of E. rheede

    Relative ends, L^2 invariants and Property (T)

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    We prove splitting theorems for groups with positive first L^2-betti number (denoted \beta^2_1) and verify Kropholler's conjecture for pairs of groups H \leq G satisfying \beta^2_1(G) &gt; \beta^2_1(H). We also prove that every n-dimensional Poincare duality group containing an (n-1)-dimensional Poincare duality group H with property (T) splits over a subgroup commensurable with H.<br/

    Identification of the sex pheromone of Nezara viridula (L.) and synthesic studies towards ephedradines A-D

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    The isolation of the sex pheromones from two populations of Nezara viridula (L.) is described. The sex pheromone produced by male N. viridula (L.), from France, was shown to comprise a 2:1 mixture of (Z)-2-[(1R*,3S*,4R*)-3,4-epoxy-4-methylcyclohexyl]-6-methyl-2,5-heptadiene and (Z)-2-[1R*,3R*,4S*)-3,4-epoxy-4-methylcyclohexyl]-6-methyl-2,5-heptadiene. The male sex pheronone from the Brazilian population was shown to be the single sesquiterpene, (Z)-(-)-2-[(1S,3R,4S)-3,4-epoxy-4-methylcyclohexyl]-6-methyl-2,5-heptadiene. The synthesis of all eight (E/Z)-2-(3,4-epoxy-4-methylcyclohexyl)-6-methyl-2,5-heptadiene isomers is described. Approaches towards 2-aryl-5-formyl-3-methoxy-carbonyl-2,3-dihydro-benzo[b]furans via hexahydro-benzo[b]furan intermediates have been investigated. A general procedure for the preparation of t -2-aryl-5-formyl-3-methoxy-carbonyl-2,3-dihydro-benzo[b]furans by the cyclisation of methyl 2-[2-benzyloxy-5-(dimethoxy-methyl)-phenyl]-3-aryl-3-hydroxypropionate derivatives has been developed. Model studies towards the enantioselective synthesis of the dihyrod-benzo[b]furan moieties of ephedradines A-D are described. Thus, (4R)-(+)-3-[(2R,3R)-2-(2-benzyloxyphenyl)-3-(4-benzyloxyphenyl)-3-hydroxy-1-oxopropyl]-4-isopropyl-2-oxazolidinone (165) was cyclised to give (4R)-(-)-3-[(2R,3R)-2-(4-hydroxyphenyl)-2,3-dihydro-benzo[b]furan-3-ylcarbonyl]-4-isopropyl-R)-(-)-3-[(2R,3R)-2-(4-hydroxyphenyl)-2,3-dihydro-benzo[b]furan-3-ylcarbonyl]-4-isopropyl-2-oxaxolidi Conditions for the condensation ofdro-benzo[b]furan-3-ylcarbonyl]-4-isopropyl-2-oxaxolidinone (166). Conditions for the condensation of boron enolates of thioesters with imines were developed. N-(tert-Butoxycarbonyl)-9-[2R*,3R*)-2-(3,4-dimethoxyphenyl)-5-formyl-2,3-dihydrobenzo[b]furan-3-yl-carbonyl]-12-phthalimido-4-p-toluene-4,9-diazadodecylamindihydrobenzo[b]furan moiety to the selectively protected spermine unit. The synthesis of the ephedradine alkaloid skeleton via an `imine cyclisation</p

    Letter to M. D. Brouhard from John L. Matthiesen, June 25, 1951, with attached documents

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    Letter to Mr. M. D. Brouhard, Editor, General Telephone Directory Co., from John L. Matthiesen, with attached documents, which are as follows: (1) Letter to Mr. John L. Matthiesen of John W. Graham and Company from M. D. Brouhard, (2) Essay regarding Father\u27s Day\u27s commercial history, (3) Note concerning Sonora Dodd and the commercial aspect of Father\u27s Day.https://digitalcommons.whitworth.edu/fathers-day-correspondence/1108/thumbnail.jp

    Measurement of the branching fractions for B--&gt; D(*)+pi(-)l(-)(nu)over-bar(l) and (B)over-bar(0)-&gt; D-(*)0 pi(+)l(-)(nu)over-bar(l)

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    We report on a measurement of the branching fractions for B- --&gt; D(*)+ pi(-)l(-)(nu) over bar (l) and (B) over bar (0) --&gt; D-(*)0 pi(+)l(-)(nu) over bar (l) with 275 x 10(6) B (B) over bar events collected at the Y(4S) resonance with the Belle detector at KEKB. Events are tagged by fully reconstructing one of the B mesons in hadronic modes. We obtain B(B- --&gt; D(+)pi(-)l(-)(nu) over bar (l)) = (0.54 +/- 0.07 (stat) +/- 0.07(syst) +/- 0.06(BR)) x 10(-2), B(B- --&gt; D*+pi(-) l(-) (nu) over bar (l)) (0.67 +/- 0.11 (stat) +/- 0.09(syst) +/- 0.03(BR)) x 10(-2), B((B) over bar (0) --&gt; D(0)pi(+)l(-) (nu) over bar (l)) = (0.33 +/- 0.06(stat) +/- 0.06(syst) +/- 0.03(BR)) x 10(-2), B((B) over bar (0) --&gt;D(*0)pi(+)l(-)(nu) over bar (l)) = (0.65 +/- 0.12(stat) +/- 0.08(syst) +/- 0.05(BR)) x 10(-2), where the third error comes from the error on (B) over bar --&gt; D((*))l(-)(nu) over bar (l) decays. Contributions from B-0 --&gt; D(*+)l(-)(nu) over bar (l) decays are excluded in the measurement of (B) over bar (0) --&gt; D(0)pi(+)l-(nu) over bar (l).Astronomy &amp; AstrophysicsPhysics, Particles &amp; FieldsSCI(E)0ARTICLE5null7
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