3,349 research outputs found
Identification of the sex pheromone of Nezara viridula (L.) and synthesic studies towards ephedradines A-D
No full textThe isolation of the sex pheromones from two populations of Nezara viridula (L.) is described. The sex pheromone produced by male N. viridula (L.), from France, was shown to comprise a 2:1 mixture of (Z)-2-[(1R*,3S*,4R*)-3,4-epoxy-4-methylcyclohexyl]-6-methyl-2,5-heptadiene and (Z)-2-[1R*,3R*,4S*)-3,4-epoxy-4-methylcyclohexyl]-6-methyl-2,5-heptadiene. The male sex pheronone from the Brazilian population was shown to be the single sesquiterpene, (Z)-(-)-2-[(1S,3R,4S)-3,4-epoxy-4-methylcyclohexyl]-6-methyl-2,5-heptadiene. The synthesis of all eight (E/Z)-2-(3,4-epoxy-4-methylcyclohexyl)-6-methyl-2,5-heptadiene isomers is described. Approaches towards 2-aryl-5-formyl-3-methoxy-carbonyl-2,3-dihydro-benzo[b]furans via hexahydro-benzo[b]furan intermediates have been investigated. A general procedure for the preparation of t -2-aryl-5-formyl-3-methoxy-carbonyl-2,3-dihydro-benzo[b]furans by the cyclisation of methyl 2-[2-benzyloxy-5-(dimethoxy-methyl)-phenyl]-3-aryl-3-hydroxypropionate derivatives has been developed. Model studies towards the enantioselective synthesis of the dihyrod-benzo[b]furan moieties of ephedradines A-D are described. Thus, (4R)-(+)-3-[(2R,3R)-2-(2-benzyloxyphenyl)-3-(4-benzyloxyphenyl)-3-hydroxy-1-oxopropyl]-4-isopropyl-2-oxazolidinone (165) was cyclised to give (4R)-(-)-3-[(2R,3R)-2-(4-hydroxyphenyl)-2,3-dihydro-benzo[b]furan-3-ylcarbonyl]-4-isopropyl-R)-(-)-3-[(2R,3R)-2-(4-hydroxyphenyl)-2,3-dihydro-benzo[b]furan-3-ylcarbonyl]-4-isopropyl-2-oxaxolidi Conditions for the condensation ofdro-benzo[b]furan-3-ylcarbonyl]-4-isopropyl-2-oxaxolidinone (166). Conditions for the condensation of boron enolates of thioesters with imines were developed. N-(tert-Butoxycarbonyl)-9-[2R*,3R*)-2-(3,4-dimethoxyphenyl)-5-formyl-2,3-dihydrobenzo[b]furan-3-yl-carbonyl]-12-phthalimido-4-p-toluene-4,9-diazadodecylamindihydrobenzo[b]furan moiety to the selectively protected spermine unit. The synthesis of the ephedradine alkaloid skeleton via an `imine cyclisation</p
Postcard from Mrs. D.L. Cooke to Sam Tanaka, August 1943
No full textPostcard from Mrs. D.L. Cooke to Sam Tanaka in the Jerome incarceration camp including a greeting and update from Cooke.The Japanese American Archival Collection documents the people, places, and daily life of Japanese Americans, primarily those who lived in the once thriving community of pre-war Florin in the Sacramento region, as well as the conditions in American incarceration camps during World War II. The approximately 7,000 original items include personal and official letters, photographs, diaries, arts and crafts, newsletters, textiles, camps artifacts, yearbooks and other publications
Coat Cooke & Joe Poole | Coat Cooke & Rainer Wiens: Reviews
No full textCoat Cooke album reviews by Randy Raine-Reusch. Coat Cooke (sax); Joe Poole (drums); Rainer Wiens (guitar)
MMP12, lung function, and COPD in high-risk populations
No full textHunninghake et al. (Dec. 31 issue)1 report an association between single-nucleotide polymorphisms (SNPs) in MMP12 and lung function in children with asthma and in adults who smoke, as well as an association with a reduced risk of chronic obstructive pulmonary disease (COPD) in adult smokers. However, a statistical genetic association may be observed when the implicated SNP is in strong linkage disequilibrium with another ungenotyped, but “causative,” SNP, often one that is in close proximity to the implicated SNP. To determine whether their findings could be explained by linkage disequilibrium, the authors present data for neighboring genes MMP3 and MMP13. Surprisingly, the authors did not present data for MMP1 (encoding interstitial collagenase), which is adjacent to MMP3 on chromosome 11 and is closer to MMP12 than is MMP13. Moreover, MMP1 has been strongly implicated in the pathogenesis of both COPD2 and asthma.3 It is a testable hypothesis that MMP1 encodes the protease that drives lung pathology. The association described by Hunninghake et al. could be attributable to SNPs within MMP1
GEORGE MELIKA, JULI PUJADE-VILLAR, JAMES A. NICHOLLS, VICTOR CUESTA-PORTA, CRYSTAL COOKE-McEWEN & GRAHAM N. STONE (2021) Three new Nearctic genera of oak cynipid gall wasps (Hymenoptera: Cynipidae: Cynipini): Burnettweldia Pujade-Villar, Melika & Nicholls, Nichollsiella Melika, Pujade-Villar & Stone, Disholandricus Melika, Pujade-Villar & Nicholls; and re-establishment of the genus Paracraspis Weld. Zootaxa, 4993: 001-081.
No full textMelika, George, Pujade-Villar, Juli, Nicholls, James A., Cuesta-Porta, Victor, Stone, Graham N. (2021): GEORGE MELIKA, JULI PUJADE-VILLAR, JAMES A. NICHOLLS, VICTOR CUESTA-PORTA, CRYSTAL COOKE-McEWEN & GRAHAM N. STONE (2021) Three new Nearctic genera of oak cynipid gall wasps (Hymenoptera: Cynipidae: Cynipini): Burnettweldia Pujade-Villar, Melika & Nicholls, Nichollsiella Melika, Pujade-Villar & Stone, Disholandricus Melika, Pujade-Villar & Nicholls; and re-establishment of the genus Paracraspis Weld. Zootaxa, 4993: 001-081. Zootaxa 5020 (3): 598-598, DOI: https://doi.org/10.11646/zootaxa.5020.3.1
Flavilla Reprehending the Intention of the Author While He Explains the Allegory
No full textMedium: stipple engraving and burin"Flavilla Reprehending the Intention of the Author While He Explains the Allegory" [1959.5514.000.000], Williamson, Thomas, Satchwell, R. WilliamArtist and Role: Satchwell, R. William, EngraverArtist and Role: Cooke, Charles, Artist IExtent: plate 15.5 x 9.
Dr. Edwin Wright Letters: George Cooke
No full textNotes - Mr. George Cooke writes of life in Athabasca Landing before the automobile arrived. Businesses, freighting, the fur trade and numerous settlers are mentioned by name (2 pages
A Pleasant conceited Comedie : Wherein is shewed how a man may chuse a good Wife from a bad. /
No full textLabel pasted on front end-paper reads: ... How a man may choose a good wife from a bad. Date of the earliest known edition, c. 1602 Reproduced in facsimile [Tudor facsimile texts] 1912.A ms. note on t.-p. ascribes the play to Joshua Cooke. "Joshua" may or may not be a mistaken reading of Jo. (i. e. John) Cooke. cf. Pref., Tudor facsimile texts.Mode of access: Internet
Common Law among the Statutes: The Lord Cooke Lecture 2007
No full textThis article is based on the 6th Lord Cooke Lecture, delivered in the Law School of the Victoria University of Wellington on 5 December 2007. The author discusses the relationship between common law and statute, a topic in which Lord Cooke had a real interest and on which he and the author discussed in person. 
The Yorkshire BARRIERS project: diagnostic analysis of barriers to research utilisation
No full textBryar, Rosamund M. ; Closs, S.Jose ; Baum, Graham ; Cooke, Jo ; Griffiths, Jane ; Hostick, Tony ; Kelly, Sarah ; Knight, Steve ; Marshall, Karen ; Thompson, David R
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