11,904 research outputs found

    The sense of a beginning : Bakhtinian dialogic criticism on 'the gospel' in Mark.

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    Contemporary literary approaches have caused paradigm shifts in Biblical Studies in the last two decades as it appears in a great deal of Markan studies using narrative, reader-response, deconstructive, feminist, and new historicist approaches. However, literary studies on the Gospel of Mark have not taken into account theoretical questions underlying those approaches. As a result biblical critics are driven by new trends without ever having a chance to examine the critical baggage of the approaches. Consequently, there is a gap of communication between the old and the new one. Therefore this thesis is an attempt to meet the need of enhancing the quality of critical endeavour in biblical studies. In the light of most recent competing critical theories of literature, the first contribution of this thesis is the methodological finding that Bakhtinian dialogic criticism contains the most profound philosophical and practical foundations for solving some crucial theoretical problems in contemporary literary theories. It is a critique to a Saussurian linguistic system of language which becomes the very foundation of modern and postmodern literary criticism. Bakhtinian literary theory shifts the foundation of literary criticism on linguistic signs into the creative activity of the socio-cultural production of human communication. The shift into socio-cultural reality of language communication makes the notion of 'genre' very important to unlock the problem of text and context in literary studies. Since the Gospel of Mark has fascinated most literary critics in Biblical Studies, the problem of 'genre' of this gospel is chosen as the focus of this study. Secondly, as no agreement is reached as to what 'genre' the Gospel of Mark belongs, this thesis makes its contribution to the discussion by locating the problem of 'genre' of Mark in the context of genre theories and argues that the Bakhtinian suggestion to find genre in the socio-cultural sphere by analysing artistic intercourse between narrative agents in Mark has freed the competing analysis from the unresolved problem between the kerygmatic (content oriented) approach and the analogical (form oriented) approach. To achieve finding 'genre' in the socio-cultural sphere, this thesis focuses on Bakhtinian analysis of the process of artistic intercourse between narrative agents. The narrative communicative interrelationships between narrative agents is constructed in this thesis as a 'stereophonic' Bakhtinian model of dialogic communication. This model is an original contribution of this thesis for revising the traditional two dimensional model of narrative communication. Based on this dialogical model of communication, a special role is given to the Bakhtinian 'author-creator' in the realization process of genre through the interaction of polyphonic voices. Through the interaction of voices of the author-artist and the hero we are led to discover a relatively stable type of portraying and controlling reality in Mark, known as the genre of Roman 'satire'. The closest literary affinity is Satyrica by Petronius. This narrative strategy of 'satire' in Mark has its root in the prophetic discourse of the Old Testament which is saturating the speech of the narrator, John the Immerser, the centurion, the people, and even Jesus. Finally, the whole search for Markan 'genre' culminates in the analysis of the realization of genre through the analysis of Bakhtinian chronotope. The reality of the genre of Mark is its social reality that is in its role as dpxrj/ 'beginning'. As the Gospel of Mark proclaims itself as 'a beginning', it defines its claim of socio-cultural 'authority' in early Christianity. It is this 'sense of beginning' which enables the narrating and the narrated world of Mark to interact dialogically

    Well-known trade mark protection: confusion in EU and Japan

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    In this thesis concerning the protection of well-known trade marks against confusion in the European Community Trade Mark (CTM) and Japanese trademark systems, the author critically considers the difficulties in comprehensively defining ‘well-known trade mark’ in the relevant international trade mark instruments. After critical analysis of various definitions of both ‘trade mark’ and ‘well-known trade mark’, she undertakes a comparison of the definitions of the parallel concepts of ‘trade mark of repute’ and ‘syuchi-syohyo’, and also undertakes an assessment as to the extent to which these trade marks are protected against confusion and kondo in the CTM and Japanese systems, respectively. It is concluded that the protection of well- known trade marks against confusion in the CTM and Japan cannot be said to be completely clear, and the author identifies some areas for legal refor

    The Gospel on the Margins: The Ideological Function of the Patristic Tradition on the Evangelist Mark

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    In spite of the virtually unanimous patristic opinion that the evangelist Mark was the interpreter of Peter, one of the most prestigious apostolic founding figures in Christian memory, the Gospel of Mark was mostly neglected in the patristic period. Not only is the text of Mark the least well represented of the canonical Gospels in terms of the number of patristic citations, commentaries and manuscripts, the explicit comments about the evangelist Mark reveal some ambivalence about its literary or theological value. In my survey of the reception of Mark from Papias of Hierapolis until Clement of Alexandria, I will argue that the reason why the patristic writers were hesitant to embrace the Gospel of Mark was that they perceived the text to be amenable to the Christological beliefs and social praxis of rival Christian factions. The patristic tradition about Mark may have little historical basis, but it had an important ideological function in appropriating the text in the name of an apostolic authority from the margins or periphery

    Appendix G. Mark–recapture models testing the effects of L. apodus density, habitat, site, and time on survival probability.

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    Mark–recapture models testing the effects of L. apodus density, habitat, site, and time on survival probability

    Cowpox virus infection in natural field vole Microtus agrestispopulations: significant negative impacts on survival

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    1. Cowpox virus is an endemic virus circulating in populations of wild rodents. It has been implicated as a potential cause of population cycles in field voles Microtus agrestis L., in Britain, owing to a delayed density-dependent pattern in prevalence, but its impact on field vole demographic parameters is unknown. This study tests the hypothesis that wild field voles infected with cowpox virus have a lower probability of survival than uninfected individuals. 2. The effect of cowpox virus infection on the probability of an individual surviving to the next month was investigated using longitudinal data collected over 2 years from four grassland sites in Kielder Forest, UK. This effect was also investigated at the population level, by examining whether infection prevalence explained temporal variation in survival rates, once other factors influencing survival had been controlled for. 3. Individuals with a probability of infection, P(I), of 1 at a time when base survival rate was at median levels had a 22.4% lower estimated probability of survival than uninfected individuals, whereas those with a P(I) of 0.5 had a 10.4% lower survival. 4. At the population level, survival rates also decreased with increasing cowpox prevalence, with lower survival rates in months of higher cowpox prevalence. 5. Simple matrix projection models with 28 day time steps and two stages, with 71% of voles experiencing cowpox infection in their second month of life (the average observed seroprevalence at the end of the breeding season) predict a reduction in 28-day population growth rate during the breeding season from λ = 1.62 to 1.53 for populations with no cowpox infection compared with infected populations. 6. This negative correlation between cowpox virus infection and field vole survival, with its potentially significant effect on population growth rate, is the first for an endemic pathogen in a cyclic population of wild rodents

    Incomprehension or resistance? : the Markan disciples and the narrative logic of Mark ‎‎4:1—8:30‎

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    The characterization of the Markan disciples has been and continues to be the object of ‎much scholarly reflection and speculation. For many, the Markan author’s presentation of ‎Jesus’ disciples holds a key, if not the key, to unlocking the purpose and function of the ‎gospel as a whole. Commentators differ as to whether the Markan disciples ultimately ‎serve a pedagogical or polemical function, yet they are generally agreed that the disciples ‎in Mark come off rather badly, especially when compared to their literary counterparts in ‎Matthew, Luke, and John. This narrative-critical study considers the characterization of the Markan disciples ‎within the Sea Crossing movement (Mark 4:1–8:30). While commentators have, on the ‎whole, interpreted the disciples’ negative characterization in this movement in terms of ‎lack of faith and/or incomprehension, neither of these, nor a combination of the two, fully ‎accounts for the severity of language leveled against the disciples by the narrator (6:52) ‎and Jesus (8:17–18). Taking as its starting point an argument by Jeffrey B. Gibson (1986) ‎that the harshness of Jesus’ rebuke in Mark 8:14–21 is occasioned not by the disciples’ ‎lack of faith or incomprehension but by their active resistance to his Gentile mission, this ‎investigation uncovers additional examples of the disciples’ resistance to Gentile mission, ‎offering a better account of their negative portrayal within the Sea Crossing movement ‎and helping explain many of their other failures. In short, this study argues that in Mark 4:1–8:26, the disciples are characterized as ‎resistant to Jesus’ Gentile mission and to their participation in that mission, the chief ‎consequence being that they are rendered incapable of recognizing Jesus’ vocational ‎identity as Israel’s Messiah (Thesis A). This leads to a secondary thesis, namely, that in ‎Mark 8:27–30, Peter’s recognition of Jesus’ messianic identity indicates that the disciples ‎have finally come to accept Jesus’ Gentile mission and their participation in it (Thesis B).‎ ‎“Chapter One: Introduction” offers a selective review of scholarly treatments of ‎the Markan disciples, which shows that few scholars attribute resistance, let alone ‎purposeful resistance, to the disciples. ‎“Chapter Two: The Rhetoric of Repetition” introduces the methodological tools, ‎concepts, and perspectives employed in the study. It includes a section on narrative ‎criticism, which focuses upon the story-as-discoursed and the implied author and reader, ‎and a section on Construction Grammar, a branch of cognitive linguistics founded by ‎Charles Fillmore and further developed by Paul Danove, which focuses upon semantic ‎and narrative frames and case frame analysis. ‎“Chapter Three: The Sea Crossing Movement, Mark 4:1–8:30” addresses the ‎question of Markan structure and argues that Mark 4:1–8:30 comprises a single, unified, ‎narrative movement, whose action and plot is oriented to the Sea of Galilee and whose ‎most distinctive feature is the network of sea crossings that transport Jesus and his ‎disciples back and forth between Jewish and Gentile geopolitical spaces. Following William Freedman, “Chapter Four: The Literary Motif” introduces two ‎criteria (frequency and avoidability) for determining objectively what constitutes a ‎literary motif and provides the methodological basis and starting point for the analyses ‎performed in chapters five and six. ‎“Chapter Five: The Sea Crossing Motif” establishes and then carries out a lengthy ‎narrative analysis of the Sea Crossing motif, which is oriented around Mark’s use of ‎θάλασσα (thalassa) and πλοῖον (ploion), and “Chapter Six: The Loaves Motif” does the same for The ‎Loaves motif, oriented around Mark’s use of ἄρτος (artos). Finally, “Chapter Seven: The Narrative Logic of the Disciples ‎‎(In)comprehension” draws together all narrative, linguistic, and exegetical insights of the ‎previous chapters and offers a single coherent reading of the Sea Crossing movement that ‎establishes Theses A and B.

    Effects of Moritella viscosa antigens on pro-inflammatory gene expression in an Atlantic salmon (Salmo salar Linnaeus) cell line (SHK-1)

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    Moritella viscosa is the causative agent of winter ulcer disease in salmonids reared in North-Atlantic countries. In this study the effects of selected M. viscosa antigens on cytotoxicity and pro-inflammatory gene expression in an Atlantic salmon (Salmo salar Linnaeus) macrophage-like cell line (SHK-1) were examined. SHK-1 cells were stimulated with live and heat-killed bacterial cells, extracellular products (ECP) and an extracellular vibriolysin, termed MvP1. Following incubation, cytotoxicity and expression levels of interleukin-1β (IL-1β) and interleukin-8 (IL-8) were examined at different time points. Both live M. viscosa cells and ECP were cytotoxic, but neither heat-killed cells, nor the MvP1 peptidase caused cell death. Expression levels of both IL-1β and IL-8 increased significantly after stimulation with live cells, but heat-killed cells only caused increased IL-8 expression. ECP did not affect IL-1β expression, but did stimulate IL-8 expression. The isolated MvP1 peptidase stimulated both IL-1β and IL-8 expression at the highest concentration tested. This study reveals a difference in the induction of pro-inflammatory gene expression in salmon SHK-1 cells between live and heat-killed M. viscosa cells, and also that an unknown secreted factor is the main stimulant of IL-β and IL-8 expression.ID: S1050464809000990; M3: Article; Accession Number: S1050464809000990; Author: Bryndis Bjornsdottir (a, b); Author: Mark D. Fast (b, 1); Author: Sandra A. Sperker (b); Author: Laura L. Brown (b, 2); Author: Bjarnheidur K. Gudmundsdottir (a, ∗); Affiliation: Institute for Experimental Pathology, University of Iceland, Keldur v/Vesturlandsveg, 112 Reykjavík, Iceland; Affiliation: National Research Council Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, Nova Scotia B3H 2Z1, Canada; Keyword: Moritella viscosa; Keyword: Extracellular products; Keyword: MvP1 vibriolysin; Keyword: Atlantic salmon; Keyword: SHK-1; Keyword: Gene expression; Keyword: Immune response; Keyword: Pro-inflammatory cytokine; Keyword: Interleukin-1β (IL-1β); Keyword: Interleukin-8 (IL-8); Number of Pages: 6; Language: English;Source type: Electronic(1

    The p36 isoform of BAG-1 is translated by internal ribosome entry following heat shock

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    BAG-1 (also known as RAP46/HAP46) was originally identified as a 46 kDa protein that bound to and enhanced the anti-apoptotic properties of Bcl-2. BAG-1 exists as three major isoforms (designated p50, p46 and p36 or BAG-1L, BAG-1M and BAG-1S respectively) and one minor isoform (p29), which are translated from a common transcript. The differing amino terminus determines both the intracellular location and the repertoire of binding partners of the isoforms which play different roles in a variety of cellular processes including signal transduction, heat shock, apoptosis and transcription. Although in vitro data suggest that the four BAG-1 isoforms are translated by leaky scanning, the patterns of isoform expression in vivo, especially in transformed cells, do not support this hypothesis. We have performed in vivo analysis of the BAG-1 5' untranslated region and shown that translation initiation of the most highly expressed isoform (p36/BAG-1S) can occur by both internal ribosome entry and cap-dependent scanning. Following heat shock, when there is a downregulation of cap-dependent translation, the expression of the p36 isoform of BAG-1 is maintained by internal ribosome entry

    LEECH: A 100 Night Exoplanet Imaging Survey at the LBT

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    In February 2013, the LEECH (LBTI Exozodi Exoplanet Common Hunt) survey began its 100-night campaign from the Large Binocular Telescope atop Mount Graham in Arizona. LEECH neatly complements other high-contrast planet imaging efforts by observing stars in L' band (3.8 microns) as opposed to the shorter wavelength near-infrared bands (1-2.3 microns). This part of the spectrum offers deeper mass sensitivity for intermediate age (several hundred Myr-old) systems, since their Jovian-mass planets radiate predominantly in the mid-infrared. In this proceedings, we present the science goals for LEECH and a preliminary contrast curve from some early data
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