132 research outputs found
Dr. Yucel Yanikdag – Faculty Author Interview
No full textDr. Yucel Yanikdag, Associate Professor of History discusses his new book, Healing the Nation: Prisoners of War, Medicine and Nationalism in Turkey, 1914-1939, published recently by Edinburgh University Press. In this book, he explores how Ottoman prisoners of war and military doctors of the First World War discursively constructed their nation as a community, and at the same time attempted to exclude certain groups from that nation. Yanikdag aims to broaden the discussion of nationalism to explore how ideological and biological factors influenced each other
Bioassay-guided isolation of wound healing active compounds from Echium species growing in Turkey
No full textEthnopharmacological relevance: The roots and root barks of Echium sp. have been used to treat ulcers, burns and wounds in traditional Turkish medicine. Aim of the study: On the basis of them traditional use and literature references, four Echium species were selected for evaluation of them wound healing potential. Isolation of active component(s) from the active extracts through the bioassay guided fractionation procedures. Material and methods: In vivo the wound healing activity of the plants was evaluated by linear incision experimental models. The chloroform extract of Echium italicum L. was fractionated by successive chromatographic techniques. Wound healing activity of each fraction was investigated following the bioassay-guided fractionation procedures. Moreover, the tissue samples of isolated compounds were examined histopathologically. The healing potential was comparatively assessed with a reference ointment Madecassol (R), which contains 1% extract of Centella asiatica. Results: Significant wound healing activity was observed from the ointment prepared with ethanol extract at 1% concentration. The ethanol root extract treated in groups of animals showed a significant increase (37.38%, 40.97% and 35.29% separately for E. italicum L, Echium vulgare Land Echium angustifolium Miller) wound tensile strength in the incision wound model. Subfractions showed significant but reduced wound healing activity on in vivo wound models. Shikonin derivatives "Acetylshikonin", "Deoxyshikonin" and "2-methyl-n-butyrylshikonin+lsovalerylshikonin", were isolated and determined as active components of active final subtraction from E. italicum L. roots. The results of histopathological examination supported the outcome of linear incision wound models. Conclusion: The experimental study revealed that Echium species display remarkable wound healing activity. (C) 2016 Published by Elsevier Ireland Ltd.Gazi University Scientific Research Foundation [02-2010/2011]This study was financially supported by Gazi University Scientific Research Foundation (Grant no: 02-2010/2011). The authors are very grateful to Professor Osman AYKUT, research assistant Gozde YUCEL and Asso. Professor Gulderen YILMAZ for their technical assistance
Characterization and comparison of mine wastes in Can Coal Basin, northwest Turkey: a case study
No full textThe Can Coal Basin is a major coal-producing site in northwest Turkey that has faced acid mine drainage problems since the 1980s. This study characterized and compared mine wastes from the Etili and Comakli open-pit coal mines in the Can Coal Basin physically, mineralogically, and geochemically for acid mine drainage potential and metal(loid) mobility. Mineralogical analysis determined pyrite to be the major sulfide mineral in the Etili and Comakli coal and mine wastes, while dolomite and calcite were abundant in the mine wastes from the Comakli site. Concentrations of Al, As, Mn, and Pb in these mine wastes are higher than in Turkish and world coals. The enrichment factor showed moderate enrichment of Pb and significant enrichment of As in the Etili and Comakli mine wastes, respectively. Static tests indicated acid generation potential in all Etili and some Comakli mine wastes. The modified synthetic precipitation leaching procedure revealed that greater concentrations of Al, Fe, Mn, Ni, Pb, and SO42- were released from pyrite-rich mine wastes. Physical, mineralogical, and geochemical factors affecting acid mine drainage were highly variable within and between sites. Increasing concern over significant environmental health effects of low-pH, metal(loid)-polluted mine wastes necessitates remediation of the mine sites.Scientific Research Projects Coordination Unit of Canakkale Onsekiz Mart University [FBA-2016-759]This research was partly supported by the Scientific Research Projects Coordination Unit of Canakkale Onsekiz Mart University under FBA-2016-759 numbered project. The author thanks to Canakkale Onsekiz Mart University Science and Technology Application and Research Center for SEM-EDX analysis. The author is grateful to Assoc. Prof. Mehmet Ali Yucel for his help during field studies, Dr. Burcu Ileri for her assistance in laboratory work and Dr. Mehmet Karadeniz for his constructive comments. Furthermore, the author special thanks to the four anonymous reviewers for their valuable suggestions
Cell Migration: GSK3β Steers the Cytoskeleton's Tip
No full textDirected cell migration polarizes the cytoskeleton, allowing the cell to move toward migratory cues. In this issue, Wu et al. (2011) demonstrate that the glycogen synthase kinase 3β (GSK3β) controls microtubule architecture and polarized movement of skin stem cells during wound healing in mammals by regulating the microtubule crosslinking protein ACF7
Efficacy Levels of Organic Acids are Used for Controlling Varroa (Varroa jacobsoni Qudemans) and Their Effects on Colony Development of Honey Bees (Apis mellifera L.)
No full textThis study was carried out to determine the effects of using formic and oxalic acids against Varroa jacobsoni Q. which is the most hazardous parasite of honey bees (Apis mellifera L.) alternately in different seasons on the efficiency in Varroa treatment and colony development of honey bees. About 35 honey bee colonies in same of queen ages (1 year old) from Buckfast race were used in the research. Colonies were equalized for natural varroa levels and adult-brood bee population, prior to the research. Colonies were selected randomly as 2 treatment groups with 14 colonies and one control group with 7 colonies in the autumn and then the treatment goups were divided into 2 for using organic acids alternately so, 5 research groups (O/F, O/O, F/F, F/O and control) were used for the following spring. Varroa levels, treatment effectiveness, adult bee and brood population growth of groups were determined in autumn and spring, before and after the research. In autumn and spring experiments, Varroa infestation levels of the treatment groups were significantly reduced after the oxalic and formic acid applications (p0.05)
Morphogens: Precise Outputs from a Variable Gradient
No full textThe morphogen gradient as a source of embryonic patterning is one of the best accepted concepts in developmental biology. Morphogens can be transcription factors or extracellular signals, but in both cases, they are thought to provide concentration thresholds that position different cell fates within the developing embryo. Several recent papers examine the patterning activities of Drosophila Bicoid, the first known molecular morphogen and reach different conclusions about the patterning power of a single morphogen gradient
Efficacy Levels of Organic Acids are Used for Controlling Varroa (Varroa jacobsoni Qudemans) and Their Effects on Colony Development of Honey Bees (Apis mellifera L.)
No full textBovine Papillomavirus Type 2 Infection and Microscopic Patterns of Urothelial Tumors of the Urinary Bladder in Water Buffaloes
No full textThis report describes the histopathology of two hundred and fifty-three mesenchymal tumors of the urinary bladder in cattle grazing on lands rich in bracken fern. Approximately 80% were hemangiomas and angiosarcomas. Hemangioma (capillary, cavernous, and large vessels) was the most frequent mesenchymal tumor and was more common than angiosarcoma. Although the appearance of endothelial cells can vary remarkably, epithelioid angiosarcomas, often containing multinucleated cells, were the most frequent malignant vascular tumors. Hemangiopericytoma and tumors of muscle and soft connective tissue origin, alone and/or in association with tumor-like lesions, were less frequently seen. Furthermore, forty-five cases of intravascular papillary endothelial hyperplasia (IPEH), a lesion not previously reported in the urinary bladder of cattle, were also described. Bovine papillomavirus type-2 DNA was amplified in tumor samples. Forty vascular tumors were investigated by dual-labeling immunofluorescence, and, for the first time, a coexpression of E5 and platelet-derived growth factor β receptor (PDGFβR) was shown to occur. The results show that the BPV-2 E5 oncoprotein binds to the activated form of the PDGFβ receptor thus playing an important role in mesenchymal as well as epithelial carcinogenesis of the urinary bladder. Furthermore, these findings demonstrate that BPV-2 infects both epithelial and mesenchymal cells
An experimental study on friction reducing polymers in turbulent pipe flow
No full textAn experimental study was conducted to search the reduction of friction in fully developed turbulent pipe flow using different types of polyacrylamides as friction reducing polymers. Pressure drop measurements determined the friction reduction. Three different polymer types Superfloc A110, Superfloc A130 and Superfloc A150 were used to examine the effect of polymer concentration, Reynolds number and polymer type on friction reduction. The Darcy friction factor was obtained for each polymer type at the polymer concentration ranging from 0 to 500 wppm and a Reynolds number range of 10000-80000. It was observed that friction factor decreased with increment in polymer concentration and Reynolds number for each polymer. Higher molecular weight polymers are more effective at reducing friction. With increasing concentration of polymer, the measured data approaches the Virk asymptote, which represents the maximum friction reduction limit by the polymers. The percentage of friction reduction increased with increasing concentration of polymer up to 100 wppm for each polymer type and then began to decrease for polymer concentrations higher than 100 wppm. An empirical formula was obtained to calculate the Darcy friction factor as a function of Reynolds number and polymer concentration for Superfloc A110.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Marine and Transport Technolog
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