878 research outputs found

    Grape seed extract: a potential adjunct to chemotherapy?

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    Ker Y Cheah, Gordon S Howarth, Susan EP Bastia

    Insulin-like growth factor-I (IGF-I) : role and application in intestinal disease / Gordon Stanley Howarth.

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    "November 2001."Author's previously published articles appended.Bibliography: leaves 80-106.xii, 139 leaves : ill, charts ; 30 cm.Describes studies which extended the understanding of growth factors, particularly of IGF-I in gut growth and repair in addition to the physiological role and hence, therapeutic potential, of a range of growth factors in gastrointestinal disease. It is suggested that future evaluation of the application of growth factors to combat gastrointestinal disorders could focus on functional outcomes such as effects on intestinal absorption. In addition, the efficacy of growth factor analogues with increased bioactivity, possibly incorporated into enterally-administered growth factor formulations, either enriched in, or depleted of, certain specific growth factors, could be investigated as a novel treatment strategy for diseases of the gastrointestinal tract.Thesis (Ph.D.)--University of Adelaide, Dept. of Physiology, 200

    δ Orionis: Further temporal variability and evidence for small-scale structure in the interstellar medium

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    We report here the detection of both spatial and temporal variations in interstellar absorption in the line of sight to δ Orionis. First, we present new high-resolution (R≈110 000) observations of the interstellar D lines of Na i towards both δ Ori A and C. Comparison of these spectra highlights variations in absorption between the two stars, indicative of small-scale spatial structure in the interstellar medium in this direction over distances of less than ≈15 000 au (the projected separation of the two stars). Components with the largest Na i column densities and lowest velocity dispersions are, in general, found to be subject to the greatest differences; in fact the narrowest component detected is only observed in one of the sightlines. This effect has also been reported by Meyer & Blades. Secondly, we present new ultra-high-resolution (R≈900 000) Na i D1 observations and high-resolution (R≈110 000) Ca ii H & K observations of δ Ori A which, through ultra-high-resolution work conducted between 1994 and 2000, has been shown to exhibit a time-variable interstellar Na i absorption component. These new observations, while revealing the further reduction in intensity of the time-variable Na i absorption, indicate constant Ca ii absorption over the same period. This results in a dramatic reduction in the Na°/Ca+ abundance ratio, perhaps indicating the line of sight to be gradually probing a less-dense outer region of an absorbing filament

    Influence of bacterial colonisation on glycosylation of intestinal mucin oligosaccharides during early development

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    Abstract W1745Rebecca E. Forder, Catherine Robbe-Masselot, Gordon S. Howarth, Robert J. Hughe

    Comparative effects of mistletoe extracts and 5-Fluorouracil chemotherapy on viability of Caco-2 and IEC-6 intestinal epithelial cells

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    Poster PresentationZahra Lotfollahi, Gordon S Howarth, Ljubov Simson, Ker Y Cheah and Susan EP Bastia

    Dietary intervention improves the survival of cultured greenlip abalone (Haliotis laevigata Donovan) at high water temperature

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    Abstract not availableDavid A.J. Stone, Matthew S. Bansemer, Brett Lange, Elise N. Schaefer, Gordon S. Howarth, James O. Harri

    Age-dependent response of digestive enzyme activities to dietary protein level and water temperature in greenlip abalone (Haliotis laevigata)

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    Abstract not availableMatthew S. Bansemer, Jian G. Qin, James O. Harris, Elise N. Schaefer, Hanru Wang, Georgia J. Mercer, Gordon S. Howarth, David A.J. Ston
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