1,721,057 research outputs found
Reduction of blocking artifact based on edge information in discrete cosine transform–coded images
Parallel-pass architecture for embedded block coding with optimal truncation in JPEG 2000
An advanced segmentation using bit-plane slicing technique in extraction of lungs region
P4‐095: CONTOURLET‐BASED FEATURE EXTRACTION FOR COMPUTER‐AIDED CLASSIFICATION OF ALZHEIMER'S DISEASE
Classification of Alzheimer’s Disease and Mild-Cognitive Impairment Base on High-Order Dynamic Functional Connectivity at Different Frequency Band
Functional brain connectivity networks obtained from resting-state functional magnetic resonance imaging (rs-fMRI) have been extensively utilized for the diagnosis of Alzheimer’s disease (AD). However, the traditional correlation analysis technique only explores the pairwise relation, which may not be suitable for revealing sufficient and proper functional connectivity links among brain regions. Additionally, previous literature typically focuses on only lower-order dynamics, without considering higher-order dynamic networks properties, and they particularly focus on single frequency range time series of rs-fMRI. To solve these problems, in this article, a new diagnosis scheme is proposed by constructing a high-order dynamic functional network at different frequency level time series (full-band (0.01–0.08 Hz); slow-4 (0.027–0.08 Hz); and slow-5 (0.01–0.027 Hz)) data obtained from rs-fMRI to build the functional brain network for all brain regions. Especially, to tune the precise analysis of the regularized parameters in the Support Vector Machine (SVM), a nested leave-one-out cross-validation (LOOCV) technique is adopted. Finally, the SVM classifier is trained to classify AD from HC based on these higher-order dynamic functional brain networks at different frequency ranges. The experiment results illustrate that for all bands with a LOOCV classification accuracy of 94.10% with a 90.95% of sensitivity, and a 96.75% of specificity outperforms the individual networks. Utilization of the given technique for the identification of AD from HC compete for the most state-of-the-art technology in terms of the diagnosis accuracy. Additionally, results obtained for the all-band shows performance further suggest that our proposed scheme has a high-rate accuracy. These results have validated the effectiveness of the proposed methods for clinical value to the identification of AD
Dissimilarity Corrective Generative Adversarial Network for Brain Image Segmentation
More accurate diagnosis of brain disorders can be achieved by properly analyzing structural changes in the brain. For the quantification of change in brain structure, the segmentation task is crucial. Recently, generative adversarial networks (GAN) have been rapidly developed and used in many fields. Segmentation of medical images with these networks will greatly improve performance. However, segmentation accuracy improvement is a challenging task. In this paper, we propose a novel corrective algorithm for updating the accuracy and a novel loss function based on dissimilarity. First, we update the generator using the typical dice similarity coefficient (DSC) as a loss function only. For the next update, we use the same image as input and obtain the output; this time, we calculate dissimilarity and update the generator again. In this way, false prediction, due to the first weight update, can be updated again to minimize the dissimilarity. Our proposed algorithm can correct the weights to minimize the error. The DSC scores obtained with the proposed algorithm and the loss function are higher, and clearly outperformed the model with only DSC as the loss function for the generator
Development of an Efficient Cascade Pathological-Brain Detection System using a Median Filter and Quadratic Discriminant Analysis
Explainable Vision Transformer with Self-Supervised Learning to Predict Alzheimer’s Disease Progression Using 18F-FDG PET
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that affects millions of people worldwide. Early and accurate prediction of AD progression is crucial for early intervention and personalized treatment planning. Although AD does not yet have a reliable therapy, several medications help slow down the disease’s progression. However, more study is still needed to develop reliable methods for detecting AD and its phases. In the recent past, biomarkers associated with AD have been identified using neuroimaging methods. To uncover biomarkers, deep learning techniques have quickly emerged as a crucial methodology. A functional molecular imaging technique known as fluorodeoxyglucose positron emission tomography (18F-FDG-PET) has been shown to be effective in assisting researchers in understanding the morphological and neurological alterations to the brain associated with AD. Convolutional neural networks (CNNs) have also long dominated the field of AD progression and have been the subject of substantial research, while more recent approaches like vision transformers (ViT) have not yet been fully investigated. In this paper, we present a self-supervised learning (SSL) method to automatically acquire meaningful AD characteristics using the ViT architecture by pretraining the feature extractor using the self-distillation with no labels (DINO) and extreme learning machine (ELM) as classifier models. In this work, we examined a technique for predicting mild cognitive impairment (MCI) to AD utilizing an SSL model which learns powerful representations from unlabeled 18F-FDG PET images, thus reducing the need for large-labeled datasets. In comparison to several earlier approaches, our strategy showed state-of-the-art classification performance in terms of accuracy (92.31%), specificity (90.21%), and sensitivity (95.50%). Then, to make the suggested model easier to understand, we highlighted the brain regions that significantly influence the prediction of MCI development. Our methods offer a precise and efficient strategy for predicting the transition from MCI to AD. In conclusion, this research presents a novel Explainable SSL-ViT model that can accurately predict AD progress based on 18F-FDG PET scans. SSL, attention, and ELM mechanisms are integrated into the model to make it more predictive and interpretable. Future research will enable the development of viable treatments for neurodegenerative disorders by combining brain areas contributing to projection with observed anatomical traits
Identification and extraction of brain tumor from MRI using local statistics of Zernike moments
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