203,827 research outputs found

    Gonzalez, D., Jr.

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    Centro Asturiano membership record of D. Gonzalez Jr.; Socio Number: 91071.https://digitalcommons.usf.edu/asturiano_membership/3338/thumbnail.jp

    Rumer's transformation: A symmetry puzzle standing for half a century

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    In 1966, only a few months after the complete elucidation of the standard nuclear genetic code (Kay, 2000), the Russian theoretical physicist Yury Borisovich Rumer uncovered the existence of a particular symmetry (Rumer, 1966): when the keto-amino transformation (also known as Rumer's transformation) is applied to the bases of a codon then the degeneracy of the transformed codon was changed. In particular, if the amino acid associated to the starting codon has degeneracy 4, then the amino acid associated to the transformed codon has degeneracy 1, 2 or 3 (and vice versa). After half a century from this discovery and despite the universality of Rumer's symmetry, little is known about its origin and its possible biological significance. In this article we show that Rumer's symmetry could have originated in an ancestral version of the genetic code, i.e., the pre-early code, and is a natural consequence of the stereo-chemical symmetries of the ancestral synthesis machinery working around such code (Gonzalez et al., 2019). Moreover, the conservation of Rumer's symmetry through evolutionary periods suggests a connection with key biological features. In this respect, intriguing possibilities include those of error detection/correction, control over the synthesis of proteins, and frame maintenance. To a certain extent, such ideas have been explored in the framework of a mathematical model of the genetic code (the non-power model of the genetic code (Gonzalez, 2004; Gonzalez, 2008; Gonzalez et al., 2016), whose definition of dichotomic classes naturally includes Rumer's symmetry (Gonzalez, 2008; Gonzalez et al., 2006, 2008) and the theory of circular codes (Arquès and Michel, 1996; Gonzalez et al., 2011; Fimmel et al., 2015)

    En la España medieval. Estudios dedicados al professor D. Julio Gonzalez Gonzalez, 1980

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    En la España medieval. Estudios dedicados al professor D. Julio Gonzalez Gonzalez, 1980. In: Cahiers de civilisation médiévale, 28e année (n°109), Janvier-mars 1985. pp. 97-98

    Eriopis loaensis Gonzalez 2014

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    Eriopis loaensis González, 2014 (Fig 3j). Examined material: 4 ex. “ Chile, J. Fernández, Róbinson Crusoe, 18-XII-1997, Col. J.C. Torres ” (MNHN). Original reference: First record of this species for Juan Fernández archipelago . Comments: The species was originally described in the Antofagasta province at the north of Chile.Published as part of Gonzalez, Guillermo, Cotoras, Darko D. & Grez, Audrey A., 2020, Annotated list of island lady beetles from Chile (Coleoptera: Coccinellidae), pp. 501-526 in Zootaxa 4852 (5) on page 512, DOI: 10.11646/zootaxa.4852.5.1, http://zenodo.org/record/441015

    On the origin of the mitochondrial genetic code: Towards a unified mathematical framework for the management of genetic information

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    The origin of the genetic code represents one of the most challenging problems in molecular evolution. The genetic code is an important universal feature of extant organisms and indicates a common ancestry of different forms of life on earth. Known variants of the genetic code can be mainly divided in mitochondrial and nuclear classes. Here we provide a new insight on the origin of the mitochondrial genetic code: we found that its degeneracy distribution can be explained by using a mathematical approach recently developed for the description of the Euplotes nuclear variant of the genetic code. The results point to a primeval mitochondrial genetic code composed of four base codons, which we call tesserae, that, among other features, exhibit outstanding error detection capabilities. The theoretical description suggests also a formulation of a plausible biological theory about the origin of protein coding. Such theory is based on the symmetry properties of hypothetical primeval chemical adaptors between nucleic acids and amino acids (ancient tRNA’s). Our paper provides a unified mathematical framework for different hypotheses on the origin of genetic coding. Also, it contributes to revisit our present view about the evolutionary steps that led to extant genetic codes by giving a new first-principles perspective on the difficult problem of the origin of the genetic code, and consequently, on the origin of life on earth

    D. Zegeri Bernardi Van-Espen ... Jus Ecclesiasticum

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    Sign.: a-b4, c5, D-Z4 2A-2Z4, 3A-3N4, 30

    Severino Gonzalez

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    Gravure représentant Severino Gonzalez, Capitaine dans l\u27armée de Jean-Jacques Dessalines (qui repoussa D-M-J de Rochambeau
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