8,814 research outputs found
Findings from the DUMA program: methamphetamine drug market trends
No full textIntroduction
Methamphetamine is a drug of national concern, with the Australian Crime Commission assessing it to be the illicit drug posing the greatest risk to the Australian community. The Australian Institute of Health and Welfare’s (AIHW) 2013 National Drug Strategy Household Survey (NDSHS) reported that approximately 400,000 Australians had used meth/amphetamines in the previous 12 months. The NDSHS reported a stable rate of meth/amphetamine use in the general community from 2010 to 2013 of 2.1 percent. However, there was a shift in the type of meth/amphetamine used, from powder to purer forms like ice or crystal methamphetamine. Specifically, powder meth/amphetamine use among recent users decreased from 51 percent to 29 percent, while ice use more than doubled from 22 percent to 50 percent. In line with this, the frequency of methamphetamine use among injecting drug users in Melbourne remained consistent from 2008 to 2014, but users reported transitioning from powder to crystal forms of methamphetamine.
Frequency of use of methamphetamine has also changed across the 2010 to 2013 period. In 2013, 15.5 percent of recent meth/amphetamine users reported daily or weekly use, compared with 9.3 percent in the 2010 survey. When examining use by form, approximately a quarter of users who mainly used ice reported using it at least weekly, compared with 2.2 percent of powder users who reported weekly use. Scott et al.’s study of injecting drug users in Melbourne found that those already using methamphetamine were starting to purchase the drug more frequently in 2013 compared with 2011
Draft toxicological profile for JP-5, JP-8, and jet A fuels
No full textA Toxicological Profile for JP-5 and JP-8 was released in 1998. This present edition supersedes any previously released draft or final profile.Chemical manager(s)/author(s): John Risher, Obaid Faroon, ATSDR, Division of Toxicology and Human Health Sciences, Atlanta, GA; Fernando Llados, Lisa Ingerman, Mario Citra, SRC, Inc., North Syracuse, NY
Shock tube study of JP-10 ignition delay time
No full textJP-10 (exo-tetrahydrodicyclopentadiene, C10H16) ignition delay times were measured in a preheated shock tube. The vapor pressures of the JP-10 were measured directly by using a high-precision vacuum gauge, to remedy the difficulty in determining the gaseous concentrations of heavy hydrocarbon fuel arising from the adsorption on the wall in shock tube experiments. The whole variation of pressure and emission of the OH or CH radicals were observed in the ignition process by a pressure transducer and a photomultiplier with a monochromator. The emission of the OH or CH radicals was used to identify the time to ignition. Experiments were performed over the pressure range of 151-556 kPa, temperature range of 1000-2100 K, fuel concentrations of 0.1%-0.55% mole fraction, and stoichiometric ratios of 0.25, 0.5, 1.0 and 2.0. The experimental results show that for the lower and higher temperature ranges, there are different dependency relationships of the ignition time on the temperature and the concentrations of JP-10 and oxygen
Dynamics of Network Formation Processes in the Co-Author Model
No full textThis article studies the dynamics in the formation processes of a mutual consent network in game theory setting: the Co-Author Model. In this article, a limited observation is applied and analytical results are derived. Then, 2 parameters are varied: the number of individuals in the network and the initial probability of the links in the network in its initial state. A simulation result shows a finding that is consistent with an analytical result for a state of equilibrium while it also shows different possible equilibria.Dynamics, Network, Game Theory, Model,Simulation, Equilibrium, Complexity
An equivalent formulation of the Fan-Raspaud Conjecture and related problems
No full textIn 1994, it was conjectured by Fan and Raspaud that every simple bridgeless cubic graph has three perfect matchings whose intersection is empty. In this paper we answer a question recently proposed by Mkrtchyan and Vardanyan, by giving an equivalent formulation of the Fan-Raspaud Conjecture. We also study a possibly weaker conjecture originally proposed by the first author, which states that in every simple bridgeless cubic graph there exist two perfect matchings such that the complement of their union is a bipartite graph. Here, we show that this conjecture can be equivalently stated using a variant of Petersen-colourings, we prove it for graphs having oddness at most four and we give a natural extension to bridgeless cubic multigraphs and to certain cubic graphs having bridges
Ephemisms as communication vehicle in the Tiv language and literature
No full textThe beauty of Tiv language and literature is achieved when communication or discourse is laced with euphemistic expressions. Euphemisms aid in turning impolite utterances into polite ones. This study, therefore, investigates the communicative potentials of euphemisms in the Tiv language and literature. The study discusses formations of euphemisms, classifies euphemisms and explores the effects of euphemisms. Connotative theory of meaning has been deployed in this study because the interpretation of euphemisms is contextually and connotatively loaded. Methodologically, the author used primary and secondary materials. The author used a participant-observation tool for data collection. Being a native speaker of the Tiv language, the author collected, translated and classified euphemisms. Secondary materials were sourced from textbooks, journal articles, online sources and dictionaries. The following findings were made: euphemisms constitute phrasal or idiomatic synonyms; they beautify or spice our daily communication; they can becloud meanings. This study will benefit preachers, writers, lecturers/teachers, researchers, semanticists, public speakers, politicians and students
Open Access to Peer-Reviewed Research through Author/Institution Self-Archiving: Maximizing Research Impact by Maximizing Online Access
No full textAll refereed journals will soon be available online; most of them already are. This means that anyone will be able to access them from any networked desk-top. The literature will all be interconnected by citation, author, and keyword/subject links, allowing for unheard-of power and ease of access and navigability. Successive drafts of pre-refereeing preprints will be linked to the official refereed draft, as well as to any subsequent corrections, revisions, updates, comments, responses, and underlying empirical databases, all enhancing the self-correctiveness, interactivity and productivity of scholarly and scientific research and communication in remarkable new ways. New scientometric indicators of digital impact are also emerging <http://opcit.eprints.org> to chart the online course of knowledge. But there is still one last frontier to cross before science reaches the optimal and the inevitable: Just as there is no longer any need for research or researchers to be constrained by the access-blocking restrictions of paper distribution, there is no longer any need to be constrained by the impact-blocking financial fire-walls of Subscription/Site-License/Pay-Per-View (S/L/P) tolls for this give-away literature. Its author/researchers have always donated their research reports for free (and its referee/researchers have refereed for free), with the sole goal of maximizing their impact on subsequent research (by accessing the eyes and minds of fellow-researchers, present and future) and hence on society. Generic (OAi-compliant) software is now available free so that institutions can immediately create Eprint Archives in which their authors can self-archive all their refereed papers for free for all forever <http://www.eprints.org/>. These interoperable Open Archives <http://www.openarchives.org> will then be harvested into global, jointly searchable "virtual archives" (e.g., <http://arc.cs.odu.edu/>). "Scholarly Skywriting" in this PostGutenberg Galaxy will be dramatically (and measurably) more interactive and productive, spawning its own new digital metrics of productivity and impact, allowing for an online "embryology of knowledge.
Why hasn't electronic bill presentment and payment taken off?
No full textThe delivery and payment of bills over the Internet could offer many advantages—low processing costs and enhanced marketing opportunities for billers, savings in time and postage for customers. Nevertheless, electronic billing has not found favor with potential users. A lack of coordination among billers and customers, combined with the high fixed costs of the new technology, may help account for the cool reception.Electronic funds transfers ; Electronic commerce ; Technology ; Payment systems
Author Correction: Discovery of fungal surface NADases predominantly present in pathogenic species.
No full textStromland O, Kallio JP, Pschibul A, et al. Author Correction: Discovery of fungal surface NADases predominantly present in pathogenic species. Nature communications. 2021;12(1): 2004
Temperature-dependent release of ATP from human erythrocytes: Mechanism for the control of local tissue perfusion
No full textCopyright @ 2012 The AuthorsThis article has been made available through the Brunel Open Access Publishing Fund.Human limb muscle and skin blood flow increases significantly with elevations in temperature, possibly through physiological processes that involve temperature-sensitive regulatory mechanisms. Here we tested the hypothesis that the release of the vasodilator ATP from human erythrocytes is sensitive to physiological increases in temperature both in vitro and in vivo, and examined potential channel/transporters involved. To investigate the source of ATP release, whole blood, red blood cells (RBCs), plasma and serum were heated in vitro to 33, 36, 39 and 42°C. In vitro heating augmented plasma or ‘bathing solution’ ATP in whole blood and RBC samples, but not in either isolated plasma or serum samples. Heat-induced ATP release was blocked by niflumic acid and glibenclamide, but was not affected by inhibitors of nucleoside transport or anion exchange. Heating blood to 42°C enhanced (P < 0.05) membrane protein abundance of cystic fibrosis transmembrane conductance regulator (CFTR) in RBCs. In a parallel in vivo study in humans exposed to whole-body heating at rest and during exercise, increases in muscle temperature from 35 to 40°C correlated strongly with elevations in arterial plasma ATP (r2 = 0.91; P = 0.0001), but not with femoral venous plasma ATP (r2 = 0.61; P = 0.14). In vitro, however, the increase in ATP release from RBCs was similar in arterial and venous samples heated to 39°C. Our findings demonstrate that erythrocyte ATP release is sensitive to physiological increases in temperature, possibly via activation of CFTR-like channels, and suggest that temperature-dependent release of ATP from erythrocytes might be an important mechanism regulating human limb muscle and skin perfusion in conditions that alter blood and tissue temperature.This article is made available through the Brunel Open Access Publishing Fund
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