11,746 research outputs found
Data set for: A Co-conformationally “Topologically” Chiral Catenane
No full textThis dataset supports the publication: A Co-conformationally “Topologically” Chiral Catenane
AUTHORS: Arnau Rodríguez-Rubio, Andrea Savoini, Florian Modicom, Patrick Butler, Stephen M. Goldup*
TITLE: A Co-conformationally “Topologically” Chiral Catenane
JOURNAL: Journal of the American Chemical Society
This dataset contains:
Characterisation data (NMR, MS, x-ray) for all the compounds reported in the manuscript
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Dataset to support Synthesis of a Mechanically Planar Chiral Rotaxane Ligand for Enantioselective Catalysis
No full textRaw characterisation data for compounds reported in: Heard, A. W., & Goldup, S. (2020). Synthesis of a mechanically planar chiral rotaxane ligand for enantioselective catalysis. Chem, 6(4), 994-1006. https://doi.org/10.1016/j.chempr.2020.02.006</span
An efficient approach to mechanically planar chiral rotaxanes
No full textWe describe the first method for production of mechanically planar chiral rotaxanes in excellent enantiopurity without the use of chiral separation techniques and, for the first time, unambiguously assign the absolute stereochemistry of the products. This proof-of-concept study, which employs a chiral pool sugar as the source of asymmetry and a high-yielding active template reaction for mechanical bond formation, finally opens the door to detailed investigation of these challenging target
Dataset for an article: A Chiral Macrocycle for the Stereoselective Synthesis of Mechanically Planar Chiral Rotaxanes and Catenanes
No full textThis dataset supports the publication: A Chiral Macrocycle for the Stereoselective Synthesis of Mechanically Planar Chiral Rotaxanes and Catenanes
AUTHORS: Shu Zhang, Arnau Rodríguez-Rubio, Abed Saady, Graham J. Tizzard, Stephen M. Goldup
JOURNAL: Chem
This dataset contains:
Characterisation data (NMR, MS, x-ray) for all the compounds reported in the manuscript
Licence: CC-BY</span
Data set for the publication 'Mechanically axially chiral catenanes and noncanonical chiral rotaxanes'
No full textThis dataset supports the publication: Mechanically axially chiral catenanes and noncanonical chiral rotaxanes
AUTHORS: John R. J. Maynard, Peter Gallagher, David Lozano, Patrick Butler, Stephen M. Goldup,*
JOURNAL: Nature Chemistry
This dataset contains:
Characterisation data (NMR, MS, x-ray) for all the compounds reported in the manuscript
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Characterisation data for An Auxiliary Approach for the Stereoselective Synthesis of Topologically Chiral Catenanes
No full textNMR, CD, HPLC, MS data for novel compounds reported in: Goldup, S. M., Denis, M., Modicom, F., & Lewis, J. E. M. (2019). An auxiliary approach for the stereoselective synthesis of topologically chiral catenanes. Chem, 5(6), 1512-1520. https://doi.org/10.1016/j.chempr.2019.03.008</span
Iterative Synthesis of Oligo[n]rotaxanes in Excellent Yield - characterisation data
No full textContains NMR characterisation data (1D and 2D; MNova format) for all novel compounds reported in the manuscript entitled "Iterative Synthesis of Oligo[n]rotaxanes in Excellent Yield” (J. Am. Chem. Soc. 2016 DOI:10.1021/jacs.6b08958) which is available on an open access basis. If any further information is required please contact Dr Goldup ([email protected]).</span
A [3]Rotaxane host selects between stereoisomers
No full textWhat has it got in its pockets? A new approach to the selective binding and reporting of stereoisomers using mechanical bonding to produce a well‐defined three‐dimensional binding pocket was recently reported by Beer and co‐workers. The highly stereoselective binding of stereoisomers by the reported [3]rotaxane suggest that the use of the mechanical bond to engineer a binding pocket has great potential for the development of stereoselective hosts
Triazole formation and the click concept in the synthesis of interlocked molecules
Full text linkThe click concept, as originally discussed by Sharpless, Finn, and Kolb, is both powerful and simple. Kolb et al. suggested that in= the search for functional molecules, chemists should focus on a small set of reactions that proceed in high yield under mild conditions and in high selectivity. Their proposal was that a relatively small number of such methodologies is sufficient to explore chemical space to solve problems in a range of disciplines, an idea pithily contained in their suggestion that chemists can obtain ‘‘diverse chemical function from a few good reactions.’’ In this perspective, we discuss how these ideas are particularly relevant in the context of the synthesis and study of mechanically interlocked molecules (MIMs), which helps to explain why the best-known click reaction, the Cu-mediated alkyne-azide cycloaddition, was adopted so rapidly by the MIM community, and highlight that more explicit application of click concepts could help drive future progress
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