30 research outputs found
THE PSYCHOLOGICAL EFFECT OF SOCIAL DISTANCING AMONG ADOLESCENTS
No full textThis paper focuses primarily on the psychological effects due to social distancing. As the outbreak of COVID-19 ensues, questions are being raised for the safety and security of people suffering from various psychological issues like depression, anxiety, loneliness and so on. While such issues are being deliberated upon, we are urged to deliberate on how isolation can affect mental health in general, especially among younger people. The goal of this paper is to address the mental effects on adolescents who might be even more ill-equipped to deal with psychological issues. It also deals with career and work-related issues that students have to worry about due to social distancing. The research methodology used in the paper includes questionnaires, surveys and literature review to understand the perspective of individuals. The paper shall also be open for further discussion on similar issues in the face of a global pandemic
Role Of Macrophages In The Cardiomyopathy Associated With Obesity And Type 2 Diabetes
No full textObesity is a state of chronic low-grade systemic inflammation that, along with type 2 diabetes (T2D), increases the risk of developing cardiovascular disease (CVD). Despite the wealth of information on the link between macrophages and cytokines in adipose tissue and peripheral insulin resistance, their role in the pathogenesis of diabetic cardiomyopathy and cardiac diastolic dysfunction is unclear. We hypothesized that activated immune cell mediators, in particular monocytes and macrophages, are fundamental drivers of diet-induced obesity and diabetic cardiomyopathy. Herein, firstly, a diet-induced model of diabetic cardiomyopathy was developed in C57BL/6 mice by feeding a high fat diet (HFD, 45% kcal fat) for 6 months, using 10% kcal fat as a control diet (CD,). Secondly, using this model, we established the inflammatory cell profile, including monocytes and macrophages, in the systemic circulation, adipose tissue, heart, and spleen during the progression of obesity, T2D and diabetic cardiomyopathy. Thirdly, the role of monocytes and macrophages in the development and progression of type 2 diabetes associated cardiomyopathy was demonstrated by their reversible and selective ablation using Macrophage Fas-Induced Apoptosis causative role in the development of diet-induced obesity/T2D and diabetic cardiomyopathy, and comprise potential immunomodulatory targets for the development of new therapies aimed at alleviating T2D, diabetic cardiomyopathy, and diastolic dysfunction
Origins and Development of Digital Journalism: Influence of Culture and Practices
No full textNotably, a Google search with the statement “articles on digital journalism” provides readers with more than 700,000 results. That number truly vouches for increasing research in this field. However, it has been over three decades since digital technologies were introduced into journalism. It is noted that not many agree with the term digital journalism and the processes attached to it. For others, it is more like a routine process; they consider it as mere “journalism” rather than digital journalism. In this chapter, while the author explores the definitions of the expression digital journalism, the researcher also comes up with a narrative review of the origins and development of this journalism stream. This chapter discusses the history of digital journalism, where the earliest reference to using technology in journalism was recorded in the 1950s. It also tries to define it through an extensive study of available literature. In this research, the author investigated and evaluated the influence of convergence culture in shaping digital journalism. This led to the current scenario where everything is interconnected, in the cloud, readily available and on-demand for consumption. While concluding this chapter, the author highlights how different streams of journalism have adjusted to the new wave of technology, giving rise to new skill-based job opportunities. Ultimately, the author elucidates how digital journalism is an ever-evolving process by discussing new and ongoing changes on various digital platforms that are changing the whole game in today’s times and will be even more relevant for future journalism practices.
Keywords: Digital Journalism, Convergence Culture, Journalism and Technology, History of Journalism, Digital Media, Evolution of Journalism
Optical image encryption using fresnel zone plate mask based on fast walsh hadamard transform
No full textKnowledge and attitude towards sterilization amongst dentists in Ludhiana, Punjab- A survey or cross sectional study
No full textThe omnipresent microorganisms are a constant threat to the health care personnel and patients by their ability to cause life threatening diseases. These microorganisms can transmit from various routes including fomites, airborne, aerosols and so on. Strict sterilization protocols and maintaining asepsis are the prerequisites to prevent cross contamination and subsequent development or establishment of disease/s. The sterile instruments are the best tools in hands of a dental health care provider. The procedures of sterilizing various reusable instruments include there cleaning after use, drying, packaging, labeling and autoclaving them. Equally important are the maintaining records of the same and checking the efficacy of the sterilizer as recommended by the authorities. This survey was done to understand the knowledge and attitude of dentists in Ludhiana towards sterilization practices. Continual in-service training is essential to expand, supplement, and refresh knowledge of different sterilizing processes and techniques to ensure safe practice for all. 
Effects of shilajit on the bone tissue of alcohol administered rats
No full textPurpose: The purpose of the current study was to examine the effect of Shilajit; a herbomineral, supplementation on the mechanical strength of alcohol treated rat bone. Methods: Experimental animals each were assigned to six groups: group A(control): control rats were given water orally for a period of ten weeks; group B (treated): Animals were given processed shilajit (PS; 100mg/kg/day); group C (treated): Animals were given processed shilajit (PS; 200mg/kg/day); group D: animals were given 30% alcohol; group E: animals were given 30% alcohol and shilajit (100mg/kg/day) orally; group F: animals were given 30% alcohol and shilajit (200mg/kg/day) orally for ten weeks. Bone tissue mechanical strength along with bone weight, liver antioxidative enzymes and alkaline phosphatase (ALP) were assessed for all the treatment groups. Results: Mechanical strength of the bone tissue (both femur as well as tibia) was found to be significantly enhanced upon shilajit supplementation to alcohol treated group. Also, the activities of anti oxidant enzymes and alkaline phosphatase in the liver of alcohol administered groups were restored upon shilajit administration. Conclusion: These findings suggest that shilajit is very efficacious and competent in the maintenance of bone health
Murder of Jamal Khashoggi: an international law perspective
No full textThe assassination of Jamal Khashoggi, a prominent Saudi Arabian journalist, inside the consulate of Saudi Arabia in Istanbul, Turkey, was sure to raise alarms in the international community. The murder was further scandalized as speculations arose about the involvement of the Crown Prince of Saudi Arabia and investigations revealed gross violations of public international law principles. This paper analyses the limits of consular immunity and the inviolability of consular premises. Further, the violation of the territorial sovereignty of Turkey is in question. It is argued that Turkey as a host country could have prevented the incident, as it was not faced with a conflict of norms because harmonious interpretation of the relevant norms was possible in this instance. An international crime of this magnitude requires the determination of the individual criminal responsibility of the Crown Prince, and a condemnation in the international community. This study is aimed at examining the major international law issues for this incident, that took place in broad daylight, under the garb of consular immunity, against a civilian in protected premises
Electrochemical Investigations of BaCe0.7-xSmxZr0.2Y0.1O3-δ Sintered at a Low Sintering Temperature as a Perovskite Electrolyte for IT-SOFCs
No full textPerovskite materials have gained a lot of interest in solid oxide fuel cell (SOFC) applications owing to their exceptional properties; however, ideal perovskites exhibit proton conduction due to availability of low oxygen vacancies, which limit their application as SOFC electrolytes. In the current project, Sm was doped at the B-site of a BaCe0.7-xSmxZr0.2Y0.1O3-δ perovskite electrolyte for intermediate-temperature solid oxide fuel cells (IT-SOFCs). BaCe0.7-xSmxZr0.2Y0.1O3-δ electrolytes were synthesized through a cost-effective coprecipitation method and were sintered at a low sintering temperature. The effects of samarium (Sm) doping on the electrochemical performance of BaCe0.7-xSmxZr0.2Y0.1O3-δ were investigated. X-ray diffraction (XRD) analysis confirmed that the BaCe0.7-xSmxZr0.2Y0.1O3-δ electrolyte material retained the perovskite structure. The secondary phase of Sm2O3 was observed for BaCe0.4Sm0.3Zr0.2Y0.1O3-δ. Scanning electron microscopic (SEM) imaging displayed the dense microstructure for all the compositions, while prominent crystal growth was observed for composition x = 0.3. The formation of the perovskite structure and the presence of the hydroxyl groups of metal oxides for all the compositions were confirmed by Fourier transform infrared spectroscopy (FTIR). An increased symmetrical disturbance was also observed for the increased doping ratio of the Sm. Thermogravimetric analysis (TGA) of all the compositions showed no major weight loss in the SOFC operating temperature range. It was also noted that the conductivity of BaCe0.7-xSmxZr0.2Y0.1O3-δ gradually decreased with the increased contents of the Sm metal. The maximum power density of 390 mW cm−2, and an open-circuit voltage (OCV) of 1.0 V at 600 °C, were obtained, showing that BaCe0.7-xSmxZr0.2Y0.1O3-δ, synthesized by a cost-effective method and sintered at a low temperature, can be used as a proton-conducting electrolyte for IT-SOFCs.Rivers, Ports, Waterways and Dredging Engineerin
Advanced Drug Delivery Systems of Curcumin for Cancer Chemoprevention
No full textAbstract
Since ancient times, chemopreventive agents have been used to treat/prevent several diseases including cancer. They are found to elicit a spectrum of potent responses including anti-inflammatory, antioxidant, antiproliferative, anticarcinogenic, and antiangiogenic activity in various cell cultures and some animal studies. Research over the past 4 decades has shown that chemopreventives affect a number of proteins involved in various molecular pathways that regulate inflammatory and carcinogenic responses in a cell. Various enzymes, transcription factors, receptors, and adhesion proteins are also affected by chemopreventives. Although, these natural compounds have shown significant efficacy in cell culture studies, they elicited limited efficacy in various clinical studies. Their introduction into the clinical setting is hindered largely by their poor solubility, rapid metabolism, or a combination of both, ultimately resulting in poor bioavailability upon oral administration. Therefore, to circumvent these limitations and to ease their transition to clinics, alternate strategies should be explored. Drug delivery systems such as nanoparticles, liposomes, microemulsions, and polymeric implantable devices are emerging as one of the viable alternatives that have been shown to deliver therapeutic concentrations of various potent chemopreventives such as curcumin, ellagic acid, green tea polyphenols, and resveratrol into the systemic circulation. In this review article, we have attempted to provide a comprehensive outlook for these delivery approaches, using curcumin as a model agent, and discussed future strategies to enable the introduction of these highly potent chemopreventives into a physician's armamentarium. Cancer Prev Res; 4(8); 1158–71. ©2011 AACR.</jats:p
