98 research outputs found
Endoscopic endonasal versus transfacial approach for blowout fractures of the medial orbital wall
No full textAbstract
In the last decades, the introduction of computed tomography has allowed an increase in the number of diagnosed fractures of the medial orbital wall. To repair medial wall fractures, many surgical techniques have been proposed (1), each one with its advantages and disadvantages. In this study, we compared endoscopic endonasal and transcutaneous reduction approaches in terms of surgery time and clinical outcome. Between 2001 and 2005, 81 patients with orbital wall fractures were treated at our department. Among these 81 patients, 24 (29.63%) were affected by a medial orbital fracture. Patients with fracture to both floor and medial walls underwent floor reduction by a transcutaneous subpalpebral approach (n = 9, 11.1%), whereas patients with isolated medial wall fracture underwent medial wall reduction by a transcutaneous subpalpebral approach using alloplastic implants (n = 8, 9.88%) or were treated by endoscopic approach (n = 5, 6.17%). After surgery, oculomotor function improved in all 22 patients. None of the patients had complications. Computed tomography revealed a well-consolidated site of fracture in both endoscopic endonasal and transcutaneous approaches. The average operating time for endoscopic endonasal and transfacial approach was 50 and 45 minutes, respectively. In this paper, the author proposed a results comparison between the endoscopic approach and the transcutaneous one
First person – Simona Amodeo
No full textABSTRACT
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Simona Amodeo is the first author on ‘Characterization of the novel mitochondrial genome replication factor MiRF172 in Trypanosoma brucei’, published in Journal of Cell Science. Simona is a PhD student in the lab of Torsten Ochsenreiter at the Institute of Cell Biology, University of Bern, Switzerland, investigating mitochondrial genome anchoring, replication and inheritance in Trypanosoma brucei.</jats:p
Calving Ease Risk Factors and Subsequent Survival, Fertility and Milk Production in Italian Holstein Cows
No full textThe objectives of this study were to investigate the main risk factors associated with calving ease (CE) in Italian Holstein cow herds, and to estimate the association between CE and subsequent survival, fertility and milk production. Data obtained from Holstein cows in 40 Italian herds were retrospectively investigated. Calvings were surveilled and classified into two categories of CE, unassisted calving or assisted calving, based on the need for intervention. The following factors were analyzed as possible risk factor affecting CE: herd, number of calvings/herd/year, age at first calving (AFC), cow parity, gestation length, twinning, calf sex, previous calving-to-conception interval, previous milk yield, dry period and close-up length, and season of calving. The association between CE and culling risk within the first 30 days-in-milk (DIM), cumulative 60-d milk yield and predicted 305-d milk yield, and pregnancy risk within 150 DIM were also investigated. Of the 47,672 calvings, 37,892 (79.5%) were unassisted, while 9780 (20.5%) required some type of assistance. Among the risk factors, only the AFC was not correlated with CE, while for all the other risk factors an association with CE was detected. Assisted calvings were associated with an increased culling risk at 30 DIM, decreased 60-d milk yield, decreased 305-d milk yield and reduced pregnancy risk at 150 DIM. In conclusion, dairy herd management should aim at correcting/reducing the risk factors in order to limit the incidence of assisted calving, and possibly improve the quality of calving assistance; controlling CE within the herd is crucial to reducing culling risk, and achieving higher lactation and reproductive performance
The Influence of Bolus of Methylprednisolone on Postorthognathic Surgery Symptoms: A Controlled Clinical Trial
No full textObjective: Despite improvements in maxillary and mandibular
osteotomy, complications still result in around 20%. Post and
intraoperative standard therapies, based on the use of betamethasone and tranexamic acid, could help to minimize the onset
of side effects. The aim of the study was to compare the role of a
supplementary bolus of methylprednisolone rather than the
standard therapy in the onset of postoperative symptoms.
Methods: The authors enrolled 10 patients, affected by class 2
and 3 Dentoskeletal, submitted to the institution for maxillomandibular repositioning osteotomy between October 2020
and April 2021. Patients were divided into 2 groups as follows: 5
patients (group A) received standard therapy consisting of the
administration of 4 mg of betamethasone, intraoperatively, and
1 g of tranexamic acid in 2 administrations. The remaining 5
patients (group B) received a supplementary bolus of 20 mg
methylprednisolone before the end of the surgery.
All patients received, in the postoperative period, 4 mg of
betamethasone every 12 hours, for 3 days. Postoperative outcomes were evaluated with a questionnaire evaluating speaking
discomfort, pain when swallowing, feeding discomfort, drinking
discomfort, swelling, and ache. Each parameter was associated
with a numeric rating scale ranging from 0 to 5.
Results: The authors observed that patients treated with a
supplementary bolus of methylprednisolone (group B) had a
statistically significant reduction of all postoperative symptoms
as compared with patients of group A (*P < 0.05, **P<0.01
Fig. 1).
Conclusion: The study highlighted that the additional bolus of
methylprednisolone improved all of the 6 parameters investigated by the questionnaire submitted to patients, resulting in a
faster recovery and improvement of the patient’s compliance
with surgery. Further studies with a larger population are
needed to confirm preliminary results
L'amore in adolescenza, tra spinte a concretizzare e castelli di sabbia: uno studio sulla rappresentazione affettiva in adolescenti maschi e femmine
No full textIl contributo esplora la rappresentazione che adolescenti, maschi e femmine, hanno della relazione di innamoramento. Lo studio riguarda 105 adolescenti (M=51; F=54; Età media=17) frequentanti un istituto superiore di Napoli; è stato chiesto di costruire una storia in relazione allo stimolo proiettivo: "Giulia e Fabrizio sono due adolescenti. La festa di compleanno di Francesco è complice del loro primo incontro. Poche parole e qualche sguardo per sentire i piacersi; sarebbe bello incontrarsi ancora. Inventa una storia!" Il corpus delle narrazioni, sottoposto a trattamento preliminare con il software TALTAC, è stato analizzato mediante il software Alceste che ha analizzato il 99.28% dell'intero corpus (UCE=1129) con un indice di stabilità di 86.27%. La classificazione discendente gerarchica ha rilevato due cluster: il primo, rappresentato dal genere maschile di età 19, presenta UCE (557) e un vocabolario specifico che evidenziano la spinta a concretizzare la relazione d'amore, che può, però, diventare intima solo quando si è grandi e maturi; il secondo, contraddistinto dal genere femminile di età 15, presenta UCE (397) e un vocabolario specifico che mostrano una dimensione esclusivamente intrapsichica e fantasticata dell'amore. Maschi e femmine sembrano vivere l'esperienza romantica secondo spinte emotive opposte: i primi agiscono la relazione senza elaborarla; le ragazze, invece, fantasticano castelli di sabbia in una dimensione isolata
Oral health related quality of life in cleft lip and palate patients rehabilitated with conventional prostheses or dental implants
No full textCleft lip and/or palate (CLP) is the most common congenital craniofacial abnormality, with a prevalence of 9.92 per 10,000 live births. In treating patients with CLP, oral rehabilitation is definitely a very important phase of the treatment in order to improve the patient's oral health related quality of life (OH-QoL). The aim of this retrospective study is to assess the OH-QoL in patients rehabilitated with different prosthetic options, thus comparing the conventional treatments, which include removable partial dentures and fixed partial dentures, with the implant-supported prostheses
Metodi attuali di rilievo per il catasto stradale
No full textViene presentata la metodologia di rilievo con GPS interferenziale cinematico per applicazioni all'aggiornamento dei dati del Caasto Strade. Le precisioni ottenibili in post-processing ed in tempo reale sono molto elevate e consentono di calcolare i raggi di curvatura, le pendenze longitudinali e trasversali ed altri parametri necessari per l'aggiornamento dei database esistenti
Prokineticin System Is a Pharmacological Target to Counteract Pain and Its Comorbid Mood Alterations in an Osteoarthritis Murine Model
No full textOsteoarthritis (OA) is the most prevalent joint disease associated with chronic pain. OA pain is often accompanied by mood disorders. We addressed the role of the Prokineticin (PK) system in pain and mood alterations in a mice OA model induced with monosodium iodoacetate (MIA). The effect of a PK antagonist (PC1) was compared to that of diclofenac. C57BL/6J male mice injected with MIA in the knee joint were characterized by allodynia, motor deficits, and fatigue. Twenty-eight days after MIA, in the knee joint, we measured high mRNA of PK2 and its receptor PKR1, pro-inflammatory cytokines, and MMP13. At the same time, in the sciatic nerve and spinal cord, we found increased levels of PK2, PKR1, IL-1β, and IL-6. These changes were in the presence of high GFAP and CD11b mRNA in the sciatic nerve and GFAP in the spinal cord. OA mice were also characterized by anxiety, depression, and neuroinflammation in the prefrontal cortex and hippocampus. In both stations, we found increased pro-inflammatory cytokines. In addition, PK upregulation and reactive astrogliosis in the hippocampus and microglia reactivity in the prefrontal cortex were detected. PC1 reduced joint inflammation and neuroinflammation in PNS and CNS and counteracted OA pain and emotional disturbances
Surgical timing of craniosynostosis: What to do and when
No full textCraniosynostosis, both isolated and syndromic, are challenging malformations for the craniofacial team. They present the team with an articulated cascade of choices, which need to be addressed early in life and in the growing age to intercept, remove, or correct the direct and indirect consequences of the malformation. Timing of treatment is thus critical and it stands on the experience of a multi-specialty trained craniofacial team. In this paper the authors discuss the timing of treatment of the major craniosynostosis, isolated and syndromic, reviewing the options for treatment and their experience in this complex field. © 2013 European Association for Cranio-Maxillo-Facial Surgery
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