548 research outputs found
Predicting Long-Term Survival in Pulmonary Arterial Hypertension More Than Just Pulmonary Vascular Resistance⁎⁎Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology.
No full textWhat Does It Mean to Say That Procedure Is Political?
No full textProcedure is not the first field of law to face controversy along these lines. Law’s independence from politics, in both its descriptive and normative aspects, is a century long legal challenge.9 This Article aims to clarify what we mean when we characterize procedure as political, as well as to understand some of the harms generated by failing to confront and acknowledge the political. This is a preliminary step in approaching future formulations of procedural rules if they cannot be depoliticized
Supplemental material for The impact of ambrisentan and tadalafil upfront combination therapy on cardiac function in scleroderma associated pulmonary arterial hypertension patients: cardiac magnetic resonance feature tracking study
No full textSupplemental material, for The impact of ambrisentan and tadalafil upfront combination therapy on cardiac function in scleroderma associated pulmonary arterial hypertension patients: cardiac magnetic resonance feature tracking study by Takahiro Sato, Bharath Ambale-Venkatesh, Joao A.C. Lima, Stefan L. Zimmerman, Ryan J. Tedford, Tomoki Fujii, Olivia L. Hulme, Erica H. Pullins, Celia P. Corona-Villalobos, Roham T. Zamanian, Omar A. Minai, Reda E. Girgis, Kelly Chin, Rubina Khair, Rachel L. Damico, Todd M. Kolb, Stephen C. Mathai, Paul M. Hassoun in Pulmonary Circulation</p
Multi-regression analysis between stable isotope composition and hydrochemical parameters in karst springs to provide insights into groundwater origin and subsurface processes: regional application to Lebanon
No full textJoint applications of isotope characterization using δ2H, δ18O and geochemical analyses have allowed for a better conceptualization of hydrological systems and helped in the evaluation and management of water resources. Processes of infiltration, and evapotranspiration (ETP), as well as mixing in the unsaturated zone, incur changes in the meteoric δ2H-δ18O signal that is transferred to groundwater during recharge. Previous studies on the isotopic composition of atmospheric precipitation highlight the importance of rainwater differentiation in terms of chemical composition and isotopic signature as a function of topographical and orographic variations as well as natural and anthropogenic impacts and identified altitude gradients for both δ2H and δ18O. In this work, a comparative correlative analysis of stable oxygen and deuterium isotopes was conducted on selected Lebanese springs. At the first stage, a hydrochemical analysis allowed the characterization of the springs and their clustering according to their predominant ionic content and aquifer units. Additionally, a multi-regression analysis reveals a relationship between hydrogen and oxygen isotopes and other easily measured parameters at the spring such as temperature, electrical conductivity, elevation, and easting and northing. The obtained relationship validated on a second campaign was attributed qualitatively to the extent and elevation of the spring catchment, the depth of flow, mixing, the snow effect, and residence time. Moreover, outliers characterized by a very large catchment area or allochthonous recharge could be outlined in the set of investigated springs. The results show that the stable isotopic signature indicative of recharge areas can be inferred based on easily measured spring parameters and can, therefore, help in the identification of protection zones and direct areas of spring recharge from a regional dataset. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature
Bronchiolitis Obliterans after Lung Transplantation: Are we making progress?
No full textOverall Goals and Objectives:
1. Understand the risk factors for Bronchiolitis Obliterans Syndrome after lung transplantation
2. Be familiar with recent developments in the therapy of Bronchiolitis Obliterans Syndrome
3. Be aware of strategies for prevention
Lokalne oblasti kot subjekti zagotavljanja javnega reda in miru
No full textPurpose:
This paper deals with the legal regulation of Estonia’s public order from the aspect of local governments. The purpose of the article is to analyse relevant Estonian legislation to help identify problems and make suggestions for improvement. Proposals are intended for the institutions involved in developing legislation in Estonia. Local governments in the country act according to the Constitution of the Republic of Estonia (1992), but still retain enough legal autonomy to decide on local affairs independently of the state government.
Methods:
The paper is based on an analysis of national legislation. In the legal research, the author pays attention to written sources of law, e.g. the Constitution of the Republic of Estonia (1992), and subsequent legal acts regulating public order.
Findings:
The main task of local government is to provide public services and improve the quality of the living environment. In Estonia, the principal provider of internal security is the Police and Border Guard Board. It is the responsibility of local government to assist the national structures in fulfilling their duties. On the other hand, the municipalities are required to ensure public order within their territories. The legal power given by parliament to local governments to carry out such activities is insufficient to ensure the law is enforced.
Practical Implications:
The findings in this paper highlight areas in which the legal regulation could be improved.
Originality/Value:
Although the legal basis for Estonian municipalities’ operations has been studied carefully, it is necessary to examine issues concerning the links between local governments and public order in detail. The continually changing legislation makes the situation complex to handle. It also provides an opportunity for international comparative analysis with other European Union member states.Namen prispevka:
Prispevek prikazuje estonsko pravno podlago zagotavljanja javnega reda in miru z vidika lokalnih oblasti. Namen prispevka je analizirati veljavno zakonodajo, identificirati težave in pripraviti predloge za izboljšave. Predlogi izboljšav so namenjeni institucijam, zadolženim za pripravo estonske zakonodaje. Lokalne oblasti sicer delujejo v skladu z estonsko ustavo, vendar imajo tudi določeno mero pravne avtonomije.
Metode:
Prispevek temelji na analizi nacionalne zakonodaje, predvsem ustave in zakonskih predpisov, ki urejajo področje javnega reda in miru.
Ugotovitve:
Glavna naloga lokalnih oblasti je zagotavljanje javnih storitev in čim večje kakovosti bivalnega okolja. Notranjo varnost v Estoniji zagotavlja policija (angl. Police and Border Guard Board), lokalne oblasti pa sodelujejo pri izpolnjevanju varnostnih nalog državnih organov ter hkrati zagotavljajo javni red in mir na svojem območju. Pooblastila lokalnih oblasti za izvajanje teh dejavnosti niso zadostna.
Praktična uporabnost:
Ugotovitve prispevka lahko pripomorejo k izboljšanju pravne ureditve.
Izvirnost/pomembnost prispevka:
V prispevku je predstavljena pravna podlaga za delovanje lokalnih oblasti na področju zagotavljanja javnega reda in miru, ki je zaradi nenehnih sprememb zakonodaje na tem področju precej zapletena. Prispevek predstavlja tudi osnovo za nadaljnjo primerjalno analizo z drugimi članicami Evropske unije
Improvement in Right Ventricular Strain with Ambrisentan and Tadalafil Upfront Therapy in Scleroderma-associated Pulmonary Arterial Hypertension
No full textProvedba crkvenog nauka o liturgijskoj inkulturaciji u Indoneziji. Slučaj reda mise na indonezijskom jeziku
No full textThough the term inculturation is a neologism, as a practice, it has been implemented by the Church since its birth. The issue of inculturation is indeed a global Church concern but has become more urgent for young Churches, including the Catholic Church in Indonesia. This article raises the problematics of liturgical inculturation in the Indonesian Catholic Church, hoping it can reflect similar issues on a broader scale. The author focuses on the implementation of the Catholic Church's teachings on liturgical inculturation, discussing the case of the formulation process of the Order of Mass in the Indonesian language. This article is based on library research examining the Church's teachings on liturgical inculturation and their implementation within the Indonesian Catholic Church through a case study of the formulation of the Order of Mass in the Indonesian language. The findings present the dynamics of liturgical inculturation movements in the Indonesian Catholic Church, ranging from strong enthusiasm – sometimes exceeding boundaries – to efforts to faithfully adhere to Church liturgical traditions in line with established norms. To a certain extent, the formulation process of the Order of Mass in the Indonesian language illustrates the practice of liturgical inculturation in Indonesia.Iako je pojam »inkulturacija« novotvorenica, kao praksu Crkva ju provodi od svog rođenja. Pitanje inkulturacije uistinu je crkveno pitanje u cijelom svijetu, ali postalo je hitnije za mlade Crkve, što uključuje i Katoličku Crkvu u Indoneziji. Ovaj članak želi pokrenuti problematiku liturgijske inkulturacije u Katoličkoj crkvi Indonezije u nadi da može poslužiti kao odraz sličnih problema u širim okvirima. Autor se usredotočuje na članak o provedbi nauka Katoličke Crkve o liturgijskoj inkulturaciji raspravljajući o slučaju procesa oblikovanja Reda mise na indonezijskom jeziku. Ovaj je članak bibliotečno istraživanje koje se temelji na nauku Crkve o liturgijskoj inkulturaciji i nastoji oko njegove provedbe u indonezijskoj Katoličkoj crkvi kroz studiju slučaja formulacije Reda mise na indonezijskom jeziku. Rezultat ovog istraživanja predstavit će postojeću dinamiku liturgijskih inkulturacijskih pokreta u indonezijskoj Katoličkoj Crkvi, koja se kreće od snažnog entuzijazma, koji može ići preko granica, do nastojanja da se poslušno slijedi tradicija crkvene liturgije u skladu s postojećim liturgijskim normama. U određenoj mjeri proces oblikovanja Reda mise na indonezijskom jeziku može prikazati praksu liturgijske inkulturacije u Indoneziji
Individualizing immunosuppression in lung transplantation
No full textImmunosuppression management after lung transplantation continues to evolve, with an increasing number of agents available for use in various combinations allowing for more choice and individualization of immunosuppressive therapy. Therapeutic developments have led to improved outcomes including lower acute rejection rates and improved survival. However, a one size fits all approach for any immunosuppressive strategy may not be best suited to the individual patient and ultimately patient specific factors must be considered when designing the immunosuppressive regimen. Recipient factors including age, race, co-morbidities, immunologic risk, genetic polymorphisms, concomitant and previous pharmacotherapy, and overall immunosuppression burden should be considered. There are several significant drug-drug interactions with select immunosuppressive agents utilized in lung transplant pharmacotherapy that must be considered when choosing and devising a dosing strategy for an individual immunosuppressive agent. Herein, considerations for immunosuppression management in the individual patient will be reviewed. </jats:p
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