87 research outputs found
Increased pulse pressure independently predicts incident atrial fibrillation in patients with type 2 diabetes.
No full textOBJECTIVEdTo examine whether baseline pulse pressure (PP), a marker of arterial stiffness,is associated with subsequent development of atrial fibrillation (AF) in type 2 diabetes.RESEARCH DESIGN AND METHODSdA total of 350 type 2 diabetic patients, whowere free from AF at baseline, were followed for 10 years. A standard electrocardiogram wasperformed annually and a diagnosis of incident AF was confirmed in affected participants by asingle cardiologist.RESULTSdDuring the follow-up, 32 patients (9.1% of total) developed incident AF. Afteradjustments for age, sex, BMI, diabetes duration, presence of left ventricular hypertrophy, hypertensiontreatment, kidney dysfunction, and pre-existing history of coronary heart disease,heart failure, and mild valvular disease, baseline PP was associated with an increased incidence ofAF (adjusted odds ratio 1.76 for each SD increment [95% CI 1.1–2.8]; P , 0.01).CONCLUSIONSdOur findings suggest that increased PP independently predicts incidentAF in patients with type 2 diabetes
Inter-atrial shunt inversion by the sitting position in a patient with a patent foramen ovale and acute pulmonary embolism.
No full textnon
Data and methodologies for a resource-efficient planning of primary and secondary aggregates in South East Europe (SEE) countries
No full textRecent, complete and reliable statistics on sources and quantities of primary and secondary aggregates, actual recycling rates, and the over- all aggregates requirements for the construction industry are core to resource-efficient planning. In the absence of such data, the objectives of the plan may be difficult or impossible to achieve, or plans created may be unrealistic or even counter-productive. It is therefore necessary to determine the degree to which these data are available, under whose jurisdiction their collec- tion, storage, and reporting falls, and whether they are currently used in planning. This is also the case in most South East Europe (SEE) coun- tries where, however, secondary aggregates are often not considered in planning for aggregates supply. The contribution of this paper is mostly focused on the definition of aggregates and the strategy to estimate the contribution of uncon- ventional aggregates, for which data gaps and uncertainties are clearly a bottleneck
Nanostructuring of metal surfaces by homoepitaxial and ion etching
No full textDottorato di ricerca in fisica. 12. ciclo. Supervisori Ugo Valbusa e Eric ChasonConsiglio Nazionale delle Ricerche - Biblioteca Centrale - P.le Aldo Moro, 7, Rome; Biblioteca Nazionale Centrale - P.za Cavalleggeri, 1, Florence / CNR - Consiglio Nazionale delle RichercheSIGLEITItal
Detection of the “Crossed Aorta Sign” during Echocardiography before Angiography
No full textWe report the case of an anomalous circumflex (Cx) origin from the right sinus of Valsalva with retroaortic course observed in a modified apical four-chamber view during transthoracic study (TTE). This finding is known as the “crossed aorta sign.” Usually, the diagnosis of this congenital anomaly of coronary circulation is established during coronary angiography. In this case, the diagnosis was performed by echocardiography before angiography. We believe that recent improvements in echocardiography increase the potential of this imaging technology also in the diagnosis of coronary artery anomalies
Controlling nutritional status score predicts 2-year outcomes in elderly patients admitted for acute heart failure
No full textBackgroundHeart failure (HF) is a major cause of death among the elderly. Its prevalence increases dramatically with age. The prevalence of malnourished subjects is high in hospitalized elderly patients. We aimed to investigate the prognostic role of malnutrition, assessed by controlling nutritional status (CONUT) score, on adverse clinical outcomes in the elderly admitted for acute HF.MethodsWe enrolled 293 patients (mean age 84 years; 48% men) consecutively admitted for acute HF to the Internal Medicine or Geriatrics Divisions at the 'IRCCS Sacro Cuore-Don Calabria' Hospital of Negrar (Verona, Italy) from 2013 to 2015. We predicted the risk of all-cause death, re-hospitalizations for HF and non-HF causes, and the composite of all-cause death or hospitalizations over 2-year follow-up. Patients were divided into four groups according to CONUT score: normal-CONUT (0-1; n = 30); mild-CONUT (2-3; n = 56); moderate-CONUT (4-7; n = 171); and severe-CONUT (>= 8; n = 36).ResultsHigher CONUT scores were associated with older age and lower entry blood pressures. No difference in hemodynamics was noted at the discharge. Kaplan-Meier curves showed a significant association between worsening CONUT scores and risk of all-cause death (p < 0.01), re-hospitalizations (p < 0.01), or both (p < 0.001). Cox regression analysis revealed these significant associations persisted after adjustment for age, sex, pre-existing cardiovascular disease, diabetes, chronic kidney disease, heart rate, systolic blood pressure, and plasma brain natriuretic peptide levels at discharge (all-cause mortality HR = 1.29 (1.00-1.66), p = 0.049; hospitalization for HF HR = 1.36 (1.03-1.81), p = 0.033; hospitalization for non-HF HR = 1.38 (1.03-1.86), p = 0.034; composite outcome HR = 1.33 (1.07-1.64), p = 0.01).ConclusionsMalnutrition, assessed by the CONUT score, is common among elderly patients admitted for acute HF and is strongly related to increased long-term risk of all-cause death and re-hospitalizations
Nonalcoholic fatty liver disease is associated with aortic valve sclerosis in patients with type 2 diabetes mellitus.
No full textBACKGROUND: Recent epidemiological data suggest that non-alcoholic fatty liver disease (NAFLD) is closely associated with aortic valve sclerosis (AVS), an emerging risk factor for adverse cardiovascular outcomes, in nondiabetic and type 2 diabetic individuals. To date, nobody has investigated the association between NAFLD and AVS in people with type 2 diabetes, a group of individuals in which the prevalence of these two diseases is high. METHODS AND RESULTS: We recruited 180 consecutive type 2 diabetic patients without ischemic heart disease, valvular heart disease, hepatic diseases or excessive alcohol consumption. NAFLD was diagnosed by liver ultrasonography whereas AVS was determined by conventional echocardiography in all participants. In the whole sample, 120 (66.7%) patients had NAFLD and 53 (29.4%) had AVS. No patients had aortic stenosis. NAFLD was strongly associated with an increased risk of prevalent AVS (odds ratio [OR] 2.79, 95% CI 1.3-6.1, p<0.01). Adjustments for age, sex, duration of diabetes, diabetes treatment, body mass index, smoking, alcohol consumption, hypertension, dyslipidemia, hemoglobin A1c and estimated glomerular filtration rate did not attenuate the strong association between NAFLD and risk of prevalent AVS (adjusted-OR 3.04, 95% CI 1.3-7.3, p = 0.01). CONCLUSIONS: Our results provide the first demonstration of a positive and independent association between NAFLD and AVS in patients with type 2 diabetes mellitus
Relation of elevated serum uric acid levels to incidence of atrial fibrillation in patients with Type 2 Diabetes Mellitus
No full textThe association between serum uric acid (SUA) levels and atrial fibrillation (AF) is currently poorly known. We examined the association between SUA levels and risk of incident AF in patients with type 2 diabetes mellitus. We followed for 10 years a random sample of 400 type 2 diabetic outpatients, who were free from AF at baseline. A standard 12-lead electrocardiography was undertaken annually and a diagnosis of incident AF was confirmed in affected participants by a single cardiologist. Over 10 years, there were 42 incident AF cases (cumulative incidence of 10.5%). Elevated SUA level was associated with an increased risk of incident AF (odds ratio 2.43, 95% confidence interval 1.8 to 3.4, p <0.0001 for each 1-SD increase in SUA level). Adjustments for age, gender, body mass index, hypertension, chronic kidney disease, electrocardiographic features (left ventricular hypertrophy and PR interval), and use of diuretics and allopurinol did not attenuate the association between SUA and incident AF (adjusted odds ratio 2.44, 95% confidence interval 1.6 to 3.9, p <0.0001). Further adjustment for variables that were included in the 10-year Framingham Heart Study-derived AF risk score did not appreciably weaken this association. Results remained unchanged even when SUA was modeled as a categorical variable (stratifying by either SUA median or hyperuricemia), and when patients with previous coronary heart disease or heart failure were excluded from analysis. In conclusion, our findings suggest that elevated SUA levels are strongly associated with an increased incidence of AF in patients with type 2 diabetes mellitus even after adjustment for multiple clinical risk factors for AF
La biblioteca professionale di Antonio e Giovanni Tagliaferri conservata nella Fondazione Ugo Da Como di Lonato del Garda. Inventario complessivo
No full textInventario critico completo delle opere monografiche e a carattere periodico che compongono la biblioteca professionale di Antonio e Giovanni Tagliaferri, oggi conservata nella Fondazione Ugo Da Como di Lonato del Garda (Brescia). Il lavoro di inventariazione, condotto dai conservatori della biblioteca Tagliaferri, è accompagnato da un ampio corredo di note critiche ed è stato curato e orientato da I. Giustina, nell'ambito delle ricerche svolte nel progetto PRIN 2008-10. l'Inventario completo ha restituito 418 opere a stampa, per un totale di più di 800 volumi, di 457 a carattere monografico e 348 a carattere periodico
- …
