1,778 research outputs found
Giovanni Battista da Sangallo e l'architettura della chiesa della Compagnia di San Giovanni Decollato a Roma
No full textAnalisi stilistica e tipologica della chiesa della Confraternita di San Giovanni Decollato. Pubblicazione di documenti e disegni inediti relativi a questo complesso e attribuzione del progetto a Giovan Battista da Sangall
Insecticidal Activity of Plant Secondary Metabolites
No full textDear Colleagues,
Plant secondary metabolites display a plethora of biological functions, among which the biochemical defense against insects and other organisms is one of the most important ones. For this purpose, they synthesize alkaloids, terpenoids, and phenolics which act as allelochemicals through highly diverse modes of action leading to major changes on the arthropods’ physiology and behavior. Thus, they represent a complementary and alternative strategy to manage populations of pests and vectors. In this framework, the present Special Issue welcomes original research articles and reviews shedding light on recent advancements about the use of plant secondary metabolites and related formulations against arthropod targets of health and agricultural importance. This Special Issue welcomes contributions on the following topics:
- Phytochemical analysis and biological evaluation of plant-borne secondary metabolites;
- Lethal and sub-lethal effects of plant-borne insecticides and acaricides;
- Repellent effects of plant-borne secondary metabolites on insects and mites;
- Modes of action of green insecticides, acaricides, and repellents;
- Toxicity of green insecticides and acaricides on non-target species, including aquatic organisms;
- Structure–activity relationships characterizing green insecticides and acaricides;
- Synergistic and antagonistic studies focusing on green insecticides and acaricides;
- Development of insecticidal and acaricidal formulations with extended shelf-life and prolonged bioactivity in the field.
Prof. Dr. Filippo Maggi
Dr. Giovanni Benelli
Guest Editor
Essential Oils from Aromatic and Medicinal Plants as Effective Weapons Against Mosquito Vectors of Public Health Importance
No full textThe fight against mosquito-borne diseases has recently seen the failure of control programmes based on synthetic chemical treatments to combat larvae and adults of mosquito vectors. This has led to several problems linked to residual substances causing a detrimental impact on environment and human health and to the development of resistance in mosquitoes. In this scenario, new eco-friendly and alternative strategies for the management of mosquito-borne diseases come from the use of plant essential oils (EOs). These are complex mixtures of small, volatile and lipophilic compounds, mostly belonging to monoterpenoids, sesquiterpenoids and phenylpropanoids, produced by aromatic plants belonging to several botanical families such as Apiaceae, Asteraceae, Geraniaceae, Lamiaceae, Lauraceae, Myrtaceae, Poaceae, Rutaceae, Verbenaceae and Zingiberaceae. An important ecological role played by EOs is defending plants from several enemies such as bacterial and fungal pathogens, viruses, insects and parasites. EOs represent ideal candidate ingredients to be incorporated in insecticidal formulations since scientific evidences have documented their efficacy against larvae and adults of several mosquitoes (e.g. Anopheles, Aedes and Culex) even at low doses (<50 ppm), the multiple mode of action and wide spectrum of efficacy, the low toxicity on nontarget organisms and environment and the unlikely capacity to induce insect resistance. In this chapter, we gave an overview of the most important EOs obtained from commercially important botanical families with documented efficacy against mosquito vectors. Particular attention has been paid to highlight their strengths and weakness and the future challenges leading to the replacement of conventional insecticides by agrochemical companies
Mating behavior of the West Nile virus vector Culex pipiens - role of behavioral asymmetries
No full textCulex pipiens is a vector of West Nile, Rift Valley fever, Japanese encephalitis and Usutu viruses. In agreement with the criteria of Integrated Vector Management, several research efforts have been devoted to develop behavior-based control tools to fight mosquito vectors. However, our knowledge of mosquito mating biology and sexual communication is still patchy. Despite the high relevance of C. pipiens as a vector of medical and veterinary importance, no studies on its mating behavior and the factors routing mating success have been conducted. In this study, I quantified the mating behavior of an Italian strain of C. pipiens, evaluating the male mating success and its potential connections with population-level lateralized traits occurring during the mating sequence. Mean copula duration exceeded 100 s. Courting males can be straightly accepted by the female after the first genital contact (38.95%), as well as after some rejection kicks performed by females with hind legs (17.89%). No copula duration differences were detected between these two cases. The overall male mating success in laboratory conditions was 56.84%. The females performing rejection kicks preferentially used right hind legs at population-level. This was confirmed over four subsequent testing phases. The number of kicks per rejection event and the rejection success were higher when right legs are used over left ones, showing a functional advantage linked with the employ of right legs. Overall, the present study represents the first quantification of the courtship and mating behavior of C. pipiens. Data on male mating success and the role population-level lateralized mating traits provides basic biological knowledge that can be helpful to optimize autocidal and behavior-based control tools
Gold nanoparticles - against parasites and insect vectors
No full textNanomaterials are currently considered for many biological, biomedical and environmental purposes, due to their outstanding physical and chemical properties. The synthesis of gold nanoparticles (Au NPs) is of high interest for research in parasitology and entomology, since these nanomaterials showed promising applications, ranging from detection techniques to drug development, against a rather wide range of parasites of public health relevance, as well as on insect vectors. Here, I reviewed current knowledge about the bioactivity of Au NPs on selected insect species of public health relevance, including major mosquito vectors, such as Aedes aegypti, Anopheles stephensi and Culex quinquefasciatus. The toxicity of Au NPs against helminths was reviewed, covering Schistosoma mansoni trematodes as well as Raillietina cestodes. Furthermore, I summarized the information available on the antiparasitic role of Au NPs in the fight against malaria, leishmaniosis, toxoplasmosis, trypanosomiasis, cryptosporidiosis, and microsporidian parasites affecting human and animals health. Besides, I examined the employ of Au NPs as biomarkers, tools for diagnostics and adjuvants for the induction of transmission blocking immunity in malaria vaccine research. In the final section, major challenges and future outlooks for further research are discussed, with special reference to the pressing need of further knowledge about the effect of Au NPs on other arthropod vectors, such as ticks, tsetse flies, tabanids, sandflies and blackflies, and related ecotoxicology assays
Spread of Zika virus: The key role of mosquito vector control
No full textMosquitoes (Diptera: Culicidae) represent a key threat for millions of humans and animals worldwide, since they act as vectors for important parasites and pathogens, including malaria, filariasis and a wide number of arboviruses. The recent outbreaks of Zika virus infections occurring in South America, Central America, and the Caribbean, represent the most recent four arrivals of important arboviruses in the western hemisphere, over the last 20 years, namely dengue, West Nile virus, and chikungunya. Since there are no specific treatments for Zika virus and the other arboviruses mentioned above, it should be highlighted that the eco-friendly and effective control of mosquito vectors is of pivotal importance. Besides radiation, transgenic and symbiont-based mosquito control approaches, an effective option may be the employ of biological control agents of mosquito young instars, in presence of ultra-low quantities of green-synthesized nanoparticles, which magnify their predation efficiency. Furthermore, behaviour-based control tools relying on the employ of swarming behaviour manipulation (i.e. the "lure and kill" approach), pheromone traps, sound traps need further research attention. In particular, detailed basic information on the physical and chemical cues routing mosquito swarming and mating dynamics is urgently required
Insecticide, Acaricide, Repellent and Antimicrobial Development
No full textThe quick spread of invasive arthropod species worldwide, sometimes boosted by global warming and urbanization [...
Mode of action of nanoparticles against insects
No full textThe employment of nanoparticles obtained through various synthesis routes as novel pesticides recently attracted high research attention. An impressive number of studies have been conducted to test their toxic potential against a wide number of arthropod pests and vectors, with major emphasis on mosquitoes and ticks. However, precise information on the mechanisms of action of nanoparticles against insects and mites are limited, with the noteworthy exception of silica, alumina, silver, and graphene oxide nanoparticles on insects, while no information is available for mites. Here, I summarize current knowledge about the mechanisms of action of nanoparticles against insects. Both silver and graphene oxide nanoparticles have a significant impact on insect antioxidant and detoxifying enzymes, leading to oxidative stress and cell death. Ag nanoparticles also reduced acetylcholinesterase activity, while polystyrene nanoparticles inhibited CYP450 isoenzymes. Au nanoparticles can act as trypsin inhibitors and disrupt development and reproduction. Metal nanoparticles can bind to S and P in proteins and nucleic acids, respectively, leading to a decrease in membrane permeability, therefore to organelle and enzyme denaturation, followed by cell death. Besides, Ag nanoparticles up- and downregulate key insect genes, reducing protein synthesis and gonadotrophin release, leading to developmental damages and reproductive failure. The toxicity of SiO2 and Al2O3 nanoparticles is due to their binding to the insect cuticle, followed by physico-sorption of waxes and lipids, leading to insect dehydration. In the final section, insect nanotoxicology research trends are critically discussed, outlining major challenges to predict the ecotoxicological consequences arising from the real-world use of nanoparticles as pesticides
Aggression in tephritidae flies: Where, when, why? Future directions for research in integrated pest management
No full textTrue fruit flies (Diptera: Tephritidae) include over 4000 species, many of which constitute enormous threats to fruit and vegetable production worldwide. A number of Tephritidae are lekking species, forming aggregations in which males fight to defend a small territory where they court females and mate. Male-male contests also occur in non-lekking species, characterized by resource defense polygyny. Tephritidae females display agonistic behavior to maintain single oviposition sites and reduce larval competition for food. Here, how, where, when and why aggressive interactions occur in Tephritidae flies is reviewed. A number of neglected issues deserving further research are highlighted, with a special focus on diel periodicity of aggression, cues evoking aggressive behavior, the role of previous experience on fighting success and the evolution of behavioral lateralization of aggressive displays. In the final section, future directions to exploit this knowledge in Integrated Pest Management, with particular emphasis on enhancement of Sterile Insect Technique and interspecific competitive displacement in the field are suggested
Plant-mediated synthesis of nanoparticles: A newer and safer tool against mosquito-borne diseases?
No full textPrevention and control of mosquito-borne diseases is a key challenge of huge public health importance. Plant-mediated synthesis of nanoparticles has recently gained attention as a cheap, rapid and eco-friendly method to control mosquito vector populations, with special reference to young instars. Furthermore, plant-fabricated nanoparticles have been successfully employed as dengue virus growth inhibitors. In this Editorial, parasitologists, entomologists and researchers in drug nanosynthesis are encouraged to deal with a number of crucial challenges of public health importance
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