1,721,112 research outputs found

    Clinical applications of multimodality cardiac imaging

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    Recent decades have brought marked advances in cardiac imaging. Although the single imaging techniques have seen their fields of application expanding, the definition of cardiac pathophysiology frequently demands a multimodality approach. In fact, multimodality imaging offers the chance to perform an integrated anatomo-functional cardiac evaluation in a completely non-invasive manner. This result is obtained by combining the information derived from mainly anatomical imaging modalities, such as multi-slice computed tomography and magnetic resonance, with the functional measures derived from nuclear imaging techniques, single photon emission computed tomography or positron emission tomography. This review will focus on the clinical applications of multimodality cardiac imaging, explaining the need for an integrated evaluation of myocardial structure and function that may enhance the clinician’s ability to characterize cardiac pathology

    Cardiac Imaging on COVID-19 Pandemic Era: the Stand, The Lost, and Found

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    PURPOSE OF REVIEW: The present review will outline the main effects of COVID-19 pandemic on cardiovascular pathologies, focusing on the role of modern non-invasive cardiac imaging techniques in this setting. RECENT FINDINGS: Multimodality cardiac imaging seems particularly suited for the in-depth characterization of patients with COVID-19, allowing the assessment of the variegated impact of the disease on the different aspects of myocardial perfusion, structure, and function. SUMMARY: The infection of SARS-CoV-2, leading to the coronavirus disease-19 (COVID-19), has represented a consistent challenge for the organization of the healthcare systems, associating to a significant increase of the fatality rate of different acute and chronic disease. Moreover, the reallocation of healthcare providers led to a significant reduction of the availability of tests and therapies, with the deferral of non-urgent tests and non-lifesaving procedures

    Multi-Modality Imaging for the Identification of Arrhythmogenic Substrates Prior to Electrophysiology Studies

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    : Noninvasive cardiac imaging is crucial for the characterization of patients who are candidates for cardiac ablations, for both procedure planning and long-term management. Multimodality cardiac imaging can provide not only anatomical parameters but even more importantly functional information that may allow a better risk stratification of cardiac patients. Moreover, fusion of anatomical and functional data derived from noninvasive cardiac imaging with the results of endocavitary mapping may possibly allow a better identification of the ablation substrate and also avoid peri-procedural complications. As a result, imaging-guided electrophysiological procedures are associated with an improved outcome than traditional ablation procedures, with a consistently lower recurrence rate

    Low dose in nuclear cardiology: state of the art in the era of new cadmium-zinc-telluride cameras

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    The use of myocardial perfusion imaging has seen a tremendous growth during the last decade and has become the most commonly used non-invasive imaging tool for risk stratification in patients with suspected and known coronary artery disease. Adherence to radiation safety best practices varied significantly between laboratories but the possibility to use the new cameras in nuclear cardiology can reduce dramatically the radiation dose without losing accuracy. Moreover, the physical characteristics of ultrafast technology could be able to open new doors for the evaluation of old parameters, changing the impact of nuclear cardiology in the diagnostic strategies

    Stress-induced alteration of left ventricular eccentricity: An additional marker of multivessel CAD

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    BackgroundAbnormal left ventricular (LV) eccentricity index (EI) is a marker of adverse cardiac remodeling. However, the interaction between stress-induced alterations of EI and major cardiac parameters has not been explored. We sought to evaluate the relationship between LV EI and coronary artery disease (CAD) burden in patients submitted to myocardial perfusion imaging (MPI).Methods and resultsThree-hundred and forty-three patients underwent MPI and coronary angiography. LV ejection fraction (EF) and EI were computed from gated stress images as measures of stress-induced functional impairment.One-hundred and thirty-six (40%), 122 (35%), and 85 (25%) patients had normal coronary arteries, single-vessel CAD, and multivessel CAD, respectively. Post-stress EI was lower in patients with multivessel CAD than in those with normal coronary arteries and single-vessel CAD (P=0.001). This relationship was confirmed only in patients undergoing exercise stress test, where a lower post-stress EI predicted the presence of multivessel CAD (P=0.039).ConclusionsPost-stress alterations of LV EI on MPI may unmask the presence of multivessel CAD

    The Evolving Role of Multimodality Imaging in Heart Failure

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    In patients with LV dysfunction, multimodality imaging offers the opportunity to obtain continued information on regional and global cardiac function, myocardial viability, coronary anatomy and regional relative or absolute myocardial perfusion. The different modalities may be performed separately and integrated/fused afterwards (i.e. through hybrid imaging) or may be used in a single step approach to define HF etiology, the extent and severity of myocardial damage/ischemia, indicate and predict the response to targeted treatments (i.e. CRT, coronary revascularization) as well as to perform pre-interventional assessment (i.e. to program trans-catheter ablation of arrhythmias or valvular interventions

    What Is New in Risk Assessment in Nuclear Cardiology?

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    : Nuclear cardiology techniques allow in-depth evaluation of cardiac patients. A body of literature has established the use of nuclear cardiology. The results obtained with traditional cameras have been reinforced by those obtained with a series of innovations that have revolutionized the field of nuclear cardiology. This article highlights the role of nuclear cardiology in the risk assessment of patients with cardiac disease and sheds light on advancements of nuclear imaging techniques in the cardiovascular field. Patient risk stratification has a key role in modern precision medicine. Nuclear cardiac imaging techniques may quantitatively investigate major disease mechanisms of different cardiac pathologies
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