1,721,053 research outputs found
Relationship between autonomic dysfunction, insulin resistance and hypertension, in diabetes
No full textSympathovagal imbalance and insulin resistance are the common underlying disorders linking hypertension and diabetes. The role of hyperinsulinemia, however, on sympathovagal balance and blood pressure has never been clearly dissected from that of hyperglycemia. Nevertheless, the study of animal models of hypertension showed that hypertension does not invariably result in the onset of insulin resistance. This suggests that insulin resistance precedes the onset of hypertension and (possibly) contributes to its pathogenesis, mainly through sympathetic activation. To examine this hypothesis, recent studies investigated the relationship between insulin sensitivity and sympathetic activity in subjects with insulin resistance but free of overt hyperglycemia and obesity, i.e., insulin-resistant offspring of type 2 diabetic patients, demonstrating a prevalence of sympathetic over vagal activity. Therefore insulin resistance and sympathovagal imbalance come before hypertension, but a clear causative role cannot be demonstrated since other mechanisms, including an inappropriate lifestyle, must be taken into account to determine clinical hypertension. Finally, several experiments in human healthy volunteers suggest that the modulation of autonomic regulation at the forearm level can regulate insulin sensitivity, tempting us to speculate that it is the primary autonomic imbalance, through vasoconstriction, that results in both insulin resistance and hypertension. In conclusion, the close relationship between autonomic imbalance, insulin resistance and hypertension is unquestionable; although logical hypothesis can be constructed, which of the three is the earliest event is still not understood, and further research is required. © 2005 Elsevier B.V. All rights reserved
Concreción y mentalización. Articulaciones de un camino psicoanalítico.
No full textEl presente trabajo, realizado a partir de un caso clínico, propone una reflexión
acerca de los resultados evolutivos que el fracaso de la función parental de proteger al
niño puede determinar en éste en términos de incapacidad de “jugar”, o sea, de aprender
a distinguir y manejar las emociones dolorosas, así como a diferenciar el mundo interior
del exterior. A partir de esto parece desarrollarse una dolorosa necesidad de llenar
concretamente el cuerpo de aquellos pensamientos y sentimientos que no encuentran
lugar en la experiencia psíquica. Por eso, dentro del espacio analítico del juego, en el que
la transferencia permite “manejar” las emociones penosas, puede facilitarse la
consecución de la mentalización y de la habilidad para diferenciar el mundo interior del
exterior, emprendiendo de esta forma el proceso de resintonización entre las experiencias
y sus representaciones.This paper, inspired by a case study, offers some ideas on developmental outcomes - in
terms of inability to "play" or to distinguish and manage the painful emotions and to
differentiate the internal from the external world - that occurs when there is a failure in
parenting child protection functioning. In this case, it appears to develop a painful need
to fill the concrete body of those thoughts and feelings that have no place in the psychic
experience. Therefore, within the analytic space of the game, in which the transferring
aims to be able to "handle" the painful emotions, we can facilitate the achievement of
mentalization and the ability to differentiate the internal from the external world, starting
the process to “retune” between experiences and their representations
“All my life ahead of me!" The issue of time in the psychotherapeutic treatment with adolescents suffering from cancer,
No full textNefrolitotomia percutanea sincrona nel trattamento della urolitiasi bilaterale: esperienza personale.
No full text
Nel nome del padre. Riflessioni sulla complementarità nelle relazioni oggettuali patogenetiche in una relazione di coppia.
No full textWorking With Couples Between Past And Present: Some Clinical Implications
No full textA clinical case of a couple psychoanalytic psychotherapy is presented in order to
highlight the difficulties and the sense of suffering present in ‘old-style marriages’
that have tried to take up the challenge of modernity. In fact, as the holding structure
of the strength of blood ties and institutionally formalised bonds carries less
weight, a greater fragility in the capacity for partners to have a relationship seems
to emerge. The authors enquire how, in the modern couple, intrapsychic aspects
might interact with the social pressures that face new relational configurations
- …
