197,839 research outputs found

    Dataset for the paper: "Di Felice, L.J.; Ripa, M.; Giampietro, M. Deep Decarbonisation from a Biophysical Perspective: GHG Emissions of a Renewable Electricity Transformation in the EU."

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    Dataset used for the development of scenarios in the publication "Di Felice, L.J.; Ripa, M.; Giampietro, M. Deep Decarbonisation from a Biophysical Perspective: GHG Emissions of a Renewable Electricity Transformation in the EU. Sustainability 2018, 10, 3685." and used for a case study in "Di Felice L., Dunlop T., Giampietro M., Kovacic Z., Renner A., Ripa M., Velasco-Fernández R. – Report on the Quality Check of the Robustness of the Narrative behind Energy Directives. MAGIC (H2020–GA 689669) Project Deliverable 5.4, 30 November 2018". (link: https://magic-nexus.eu/documents/d54-report-narratives-behind-energy-directives). Sources of other secondary data (from papers, reports) specified in the dataset (under tab "input codes")</p

    An application of MSIASM to Chinese exosomatic energy metabolism

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    The methodology of Multi-Scale Integrated Analysis of Societal Metabolism (MSIASM) is applied to analyze the Chinese economy. This paper presents four tasks: (i) identifying a set of benchmarks that makes it possible to compare various characteristics of the Chinese economy with those of other country groups and the world (level) average; (ii) explaining the differences over the selected set of benchmarks, by looking at the characteristics of the various sub-sectors of the Chinese economy; (iii) understanding existing trends and future feasible future development paths for China by studying the existence of reciprocal constraints between the whole economy and its sub-sectors; andChina, Energy, Multi-Scale Integrated Analysis, Societal Metabolism,

    Human tuberculosis II. m. tuberculosis mechanisms of genetic and phenotypic resistance to anti-tuberculosis drugs

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    The great progress of knowledge of both M. tuberculosis physiology and how human host and bacilli interact has provided fertile ground for improving diagnosis and cure of TB infection. Once M. tuberculosis has infected humans, it elaborates strategies for evading the risk to killing by the cells of the host immune system and by the anti-tuberculosis (anti-TB) agents employed to cure infection. These strategies give rise to a bacterial multidrug resistance (MDR) status. This stems firstly from genetic mutations targeting a constellation of drug-processing mechanisms that still need full identification, as drug efflux pumps and drug activating/inactivating enzymes (genetic resistance). Secondly, from the bacterial adaptation to stressful environmental conditions by adopting a temporary dormancy state lasting for decades and characterized by indifference to anti-TB drugs (phenotypic resistance or tolerance). The clarification of the strategies elaborated for surviving by M. tuberculosis has brought to the identification in the last few years of a number of mycobacterial molecular targets worth to exploitation for the development of novel and powerful anti-TB drugs. These targets include drug-efflux pump systems, considered partly responsible for genetic multi-drug resistance, and several enzymes and pump systems, as well, that sustain the metabolic adaptations of M. tuberculosis in the host and give rise to its phenotypic drug resistance

    Leukocyte Mitochondrial Membrane Potential in Type 1 Diabetes

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    Knowledge of mitochondria bioenergetics and network behaviour is rapidly expanding. Mitochondrial ␣␣m can now be investigated not only in cultured cells but also in clinical settings using fluorescent probes and living whole blood cells. The phenomenon of heterogeneity in mitochondrial ␣␣m has been observed in several cell types. Mitochondrial depolarisation/hyperpolarisation should represent a molecular switch in T cell signalling pathways and could have a role in autoimmunity. The manuscript discusses the problematic interpretation of measured changes in peripheral leukocyte ␣␣m in human health disorders, with special attention to diabetes, taken into account that mitochondrial homeostasis reflects an intricate balance of many (not well known) factors

    Giampietro Antonio Corner, attribuito, Ritratto dell’abate Pietro Donà

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    Scheda di un disegno raffigurante l'abate Pietro Donà, protagonista della rinascita intellettuale, nella seconda metà del XV secolo, del monastero di San Michele in Isola, appartenente alla cosiddetta "Pinacoteca Corneliana"; autore del disegno potrebbe essere stato lo stesso raccoglietore, l'abate Giampietro Antonio Corne

    Datasets for paper 'Cabello, V., Renner, A., Giampietro, M. 2019. Relational analysis of the resource nexus in arid land crop production. Advances in Water Resources 130:258-629'

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    Datasets produced for the paper Cabello, V., Renner, A., Giampietro, M. 2019. Relational analysis of the resource nexus in arid land crop production. Advances in Water Resources 130:258-269</p
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