213 research outputs found
Electronic spectroscopy of carbon chain radicals using cw cavity ring down in conjunction with mass detection
No full textThe electronic absorption spectrum of the 2A'' − X 2A'' origin band of the
nonlinear carbon chain radical C6H4
+ was rotationally resolved by cw-CRD
spectroscopy [41]. It was analysed using a least-squares method and the rotational
constants of the ground and excited states were determined accurately. The 581 nm
band observed under the same discharge conditions is assigned to the same electronic
transition of C6H4
+ but involving the excitation of the ν12 vibrational mode in the
upper state based on comparison with ab initio results. The presented data provide a
basis for future observations of the C6H4
+ radical in both millimeter and infrared
regions.
A linear time-of-flight mass spectrometer was constructed to provide on-line
monitoring of the plasma discharge with a mass resolution of 1 amu at a range up to
120 amu. The results from the acetylene/helium plasma discharge are in good
agreement with those obtained using the reflectron TOF mass spectrometer and a
similar ion source [42]. To improve the experimental set-up, the following
modifications can be made:
• Transferring the signal from the oscilloscope directly to a PC via a
GPIB card will increase the speed of data processing;
• Computer control of the voltage applied will make the spectrometer
easier to operate;
• Using a metal grid at ground potential in front of MCP detector will
increase the flight time of ions improving the mass resolution;
• Installing a focusing lens will increase the number of ions arriving at
the detector, and therefore increase the signal on the oscilloscope
A second greek account of the revolution of a) Pseudo-Dmitriy (Russia, 1605-1606) : Codex Iviron 710, ff. 100rv
No full textThe author publishes, with commentary and english translation, the text of the Διήγησις περ'ι τής έν ’Ρωσία έπαναστάσεως τοϋ ψενδο - Δημητρίον (An account of the revolution of pseudo-Dmitriy, untitled), Codex Iviron 710, ff. 100rv, which recounts certain events relating to the activity ofthe first pseudoDmitriy (1605-1606)
OCCASIONAL ONOMASTICON OF A CYCLE OF NOVELS ABOUT TANYA GROTTER BY DMITRIY EMETS AS A LINGUOCULTURAL PHENOMENON
No full textThis article discusses the specificity of occasional onomasticon in the cycle of novels
by Dmitriy Emets (b. 1974) featuring Tanya Grotter, which is an outstanding example
of fantasy literature, playing an important role in the modern cultural space, and
targeted mainly at children and teenagers. It has been established that while creating
the onomastic space of the cycle the author draws parallels with J. Rowling’s novels
about Harry Potter and forms onyms – occasionalisms based on the precedent names
(folk, mythological, religious, literary, and historical), foreign language vocabulary,
phraseology, etc. The desire to comprehend the author’s intention and to understand the
characteristics presented in onyms not only motivates readers to expand their horizon,
but also engages them in cross-cultural communication
Sex-specific modulation of anxiety-like behavior by forebrain neuronal SMC3 in mice
No full textAbstract SMC3 is a chromatin binding factor that plays central roles in genome organization and in proper neurodevelopment. Mutations in SMC3 gene (SMC3) induce neurodevelopmental and behavioral phenotypes in humans, including changes in anxiety behavior and self-injury. However, it is not clear what are the exact roles of SMC3 in behavior in adulthood or if its effects are only developmental. Using an adult forebrain excitatory neuron specific Smc3 knockout mouse model, the current study determined specific sex-dependent effects of SMC3 ablation during adulthood. Behavioral tests identified anxiolytic effects of Smc3 knockout in females and anxiogenic effects in males four weeks after initiation of adult knockout. The prefrontal cortex, a regulator of anxiety behavior, also displayed sex-dependent effects in dendritic branching. Transcriptional analysis revealed gene expression effects of Smc3 knockout in males and females, including changes in anxiety-related genes and relevant transcriptional pathways. While effects on anxiety behavior was sex-specific, both males and females developed self-injury behavior at approximately ten weeks after induction of knockout. The current study suggests that neuronal SMC3 modulates anxiety during adulthood in a sex-specific manner
The psychedelic psilocybin and light exposure have similar and synergistic effects on gene expression patterns in the visual cortex
No full textAbstract Psilocybin, a psychedelic compound found in specific hallucinogenic mushrooms, is known to induce changes in visual perception and experience in humans. However, there is little knowledge of the molecular mechanisms through which psilocybin affects vision-associated regions in the brain, such as the visual cortex. The current study determined both psilocybin-induced and experience-dependent changes (exposure to light) in visual cortex gene expression in mice. Of great interest, psilocybin induced robust gene expression changes in the visual cortex that closely mirror light-induced gene expression changes, even when the mice are kept in the dark. These gene expression changes correspond to specific molecular pathways, including synaptic functioning, and represent genes expressed in specific subtypes of neurons. In addition, exposure to both psilocybin and light induced synergetic changes in genes involved in epigenetic programming. Overall, the study determined that psilocybin induces robust changes in gene expression in the visual cortex that may have functional consequences in visual perception both in the absence and in synergy with visual experience
Book of Abstracts of the Minisymposium on Publicly Available Geometric/Topological Software
No full textNeuronal CTCF Is Necessary for Basal and Experience-Dependent Gene Regulation, Memory Formation, and Genomic Structure of BDNF and Arc
No full textSummaryCCCTC-binding factor (CTCF) is an organizer of higher-order chromatin structure and regulates gene expression. Genetic studies have implicated mutations in CTCF in intellectual disabilities. However, the role of CTCF-mediated chromatin structure in learning and memory is unclear. We show that depletion of CTCF in postmitotic neurons, or depletion in the hippocampus of adult mice through viral-mediated knockout, induces deficits in learning and memory. These deficits in learning and memory at the beginning of adulthood are correlated with impaired long-term potentiation and reduced spine density, with no changes in basal synaptic transmission and dendritic morphogenesis and arborization. Cognitive disabilities are associated with downregulation of cadherin and learning-related genes. In addition, CTCF knockdown attenuates fear-conditioning-induced hippocampal gene expression of key learning genes and loss of long-range interactions at the BDNF and Arc loci. This study thus suggests that CTCF-dependent gene expression regulation and genomic organization are regulators of learning and memory
Non-commutative differentiation and estimates on operator integrals
No full textIn 2017 Martijn Caspers, Fedor Sukochev and Dmitriy Zanin published a paper which generalises the proof of Davies' 1988 paper, and thus resolves the Nazarov-Peller conjecture. The proofs of these papers have been presented in this thesis. They have been expanded with a proof that generalises the conjecture to arbitrary Schatten classes. The optimality of the estimates in the conjecture is also studied, following the example of the 2016 paper by Coine et al. In addition, the quantum mechanical context is provided to interpret the presented results.Applied Mathematic
DEVELOPMENT OF E-GOVERNMENT: THE EU AND RUSSIA EXPERIENCE IN COMPARATIVE PERSPECTIVE
No full textThis paper is dedicated to research of different aspects of development of eGovernment mechanisms. Activities and state of play in the sphere within the European Union and the Russian Federation have been analyzed and compared by the author.
The author paid particular attention to the process of implementation of relevant EU legislation in the legal systems of EU Member States. To illustrate the process was chosen Ireland. The paper considers main Russian legal instruments for development of the eGovernment concept. The author outlines existing obstacles and proposes some ways to overcome them
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