475 research outputs found

    Student Teaching Internship, Monsignor John R. Hackett High School

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    6 p.The author describes her experience as a high school student teacher.Monsignor John R. Hackett High School. Kalamazoo, Michigan

    14th annual John Perkins Lecture

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    Dr. John Perkins returns to campus Tuesday, April 30, 11 a.m., at First Free Methodist Church, for the 14th annual John Perkins Lecture Series. This year’s morning event features Erna Kim Hackett, executive pastor at The Way Berkeley. Later that day, Hackett and Dr. Perkins will continue the morning’s topic, “Words Have Power,” at 7:30 p.m., also in First Free Methodist Church. John Perkins is one of the leading evangelical voices to come out of the American civil rights movement and an internationally known author, speaker, and teacher. His is the co-founder of SPU’s John Perkins Center for Reconciliation, Leadership Training, and Community Development and the author of the new book One Blood: Parting Words to the Church on Race and Love. Erna Kim Hackett served with InterVarsity for 18 years in Black Ministries and Urban Programs. She is a preacher, pastor, writer, activist, and singer

    2007 - biennial review - 2009

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    Reporting period: July 1, 2007-June 30, 2009.Assembled and reviewed by: Reagan Waskom, Nancy Grice, Zach Hittle, Kevin Hackett

    Corrigendum to “Accumulation and potential for transport of microplastics in stormwater drains into marine environments, Perth region, Western Australia” [Mar. Pollut. Bull. 168 (2021) 112362]

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    The authors regret that the original manuscript failed to appropriately acknowledge all sources of intellectual and technical contribution, which warrant co-authorship. Dr Mark J Hackett (School of Molecular and Life Sciences, Curtin University, Bentley 6102 WA, Australia) is now recognised as a co-author of this manuscript with respect to intellectual input into the design of ATR-FTIR experiments and interpretation of the ATR-FTIR spectra. Dr Hackett is also recognised as the sole co-author responsible for training the first author of this paper in the use of ATR-FTIR research equipment. The ATR-FTIR equipment used for this study is housed within the School of Molecular and Life Sciences at Curtin University, and all authors gratefully acknowledge Curtin University for providing access to this equipment. The authors would like to apologise for any inconvenience caused. Natasha Lutz: Conceptualization, Methodology, Software, Data curation, Investigation, Formal analysis, Visualization, Writing – original draft, Writing – review & editing. James Fogarty: Data curation, Formal analysis, Methodology, Writing – review & editing, Supervision. Andrew Rate: Conceptualization, Methodology, Writing – review & editing, Supervision. Mark J. Hackett: Investigation, Data curation, Visualization

    MCL-1 localizes to sites of DNA damage and regulates DNA damage response

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    MCL-1, a pro-survival member of the BCL-2 family, was previously shown to have functions in ATR-dependent Chk1 phosphorylation following DNA damage. To further delineate these functions, we explored possible differences in DNA damage response caused by lack of MCL-1 in mouse embryo fibroblasts (MEFs). As expected, Mcl-1(-/-) MEFs had delayed Chk1 phosphorylation following etoposide treatment, compared to wild type MEFs. However, their response to hydroxyurea, which causes a G(1)/S checkpoint response, was not significantly different. In addition, appearance of gamma-H2AX was delayed in the Mcl-1(-/-) MEFs treated with etoposide. We next investigated whether MCL-1 is present, together with other DNA damage response proteins, at the sites of DNA damage. Immunoprecipitation of etoposide-treated extracts with anti-MCL-1 antibody showed association of MCL-1 with gamma-H2AX as well as NBS1. Immunofluorescent staining for MCL-1 further showed increased co-staining of MCL-1 and NBS1 following DNA damage. By using a system that creates DNA double strand breaks at specific sites in the genome, we demonstrated that MCL-1 is recruited directly adjacent to the sites of damage. Finally, in a direct demonstration of the importance of MCL-1 in allowing proper repair of DNA damage, we found that treatment for two brief exposures to etoposide , followed by periods of recovery, which mimics the clinical situation of etoposide use, resulted in greater accumulation of chromosomal abnormalities in the MEFs that lacked MCL-1. Together, these data indicate an important role for MCL-1 in coordinating DNA damage mediated checkpoint response, and have broad implications for the importance of MCL-1 in maintenance of genome integrity.Peer reviewedfinal article publishedprotein complexchromosomesG2/McheckpointDNA repai

    Facet Theory and the Mapping Sentence: Evolving Philosophy, Use and Application

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    How do we think about the worlds we live in? The formation of categories of events and objects seems to be a fundamental orientation procedure. Facet theory and its main tool, the mapping sentence, deal with categories of behavior and experience, their interrelationship, and their unification as our worldviews. In this book Hackett reviews philosophical writing along with neuroscientific research and information form other disciplines to provide a context for facet theory and the qualitative developments in this approach. With a variety of examples, the author proposes mapping sentences as a new way of understanding and defining complex behavior

    Co-authoring in Academic Research:From quarter-baked intuition to publication

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    Dr Ciara Hackett (QUB School of Law) and Prof Harry Van Buren (the University of Tennessee at Chattanooga and Honorary Professor, QUB School of Law) speak with Dr Ciarán O’Kelly about co-authoring in academic research.They ask how accurate and, indeed, how healthy it is to think of academics as solitary actors. They discuss both the merits of and the challenges involved in collaboration and co-authoring. Who ought one co-author with? What workflows work best? What ethical issues emerge

    Co-authoring in Academic Research:From quarter-baked intuition to publication

    No full text
    Dr Ciara Hackett (QUB School of Law) and Prof Harry Van Buren (the University of Tennessee at Chattanooga and Honorary Professor, QUB School of Law) speak with Dr Ciarán O’Kelly about co-authoring in academic research.They ask how accurate and, indeed, how healthy it is to think of academics as solitary actors. They discuss both the merits of and the challenges involved in collaboration and co-authoring. Who ought one co-author with? What workflows work best? What ethical issues emerge

    Making use of historical case material – the problems of looking back and the implications for service development in relation to research and evaluation activities

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    This methodological paper details the process of embarking on a follow-up study of young people with sexual behaviour problems who were known to services in the 1990s and who are now young adults in their twenties or early thirties. In the context of the importance of such follow-up work, the overall aim and objectives of the funded research project are specified and the challenges presented in setting up research partnerships with service sites, including the negotiation of access and ethical approval, are the subject of overview and reflection. The practicalities of beginning the fieldwork which comprised an initial analysis of historical case material held in the research sites are then detailed and the solutions to the problems encountered are explained. The article concludes by identifying the kinds of questions services and researchers need to consider when wanting to engender or enhance a research culture which is facilitative of this kind of outcome research. These relate to the resources necessary to support a research culture, the requirements of data protection and ethical approval processes, obtaining service user consent to participate in future research, secure but accessible storage of records, staff development and researchers’ obligations to minimise disruption to already hard pressed services

    2019 Purdue Road School Transportation Conference and Expo Luncheon

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    Jim Hackett is president and chief executive officer, Ford Motor Company, effective May 22, 2017. He also is a member of the company’s board of directors. Under Hackett’s leadership, together with Bill Ford, Ford Motor Company is committed to becoming the world’s most trusted company, designing smart vehicles for a smart world that help people move more safely, confidently and freely. Prior to serving in this role, Hackett was named chairman of Ford Smart Mobility LLC in 2016, a subsidiary of Ford formed to accelerate the company’s plans to design, build, grow and invest in emerging mobility services. Before joining Ford Smart Mobility, he was a member of the Ford Motor Company Board of Directors from 2013-2016. Hackett was vice chairman of Steelcase, the global leader in the office furniture industry, from 2014 to 2015. He retired as CEO of Steelcase in February 2014, after having spent 20 years leading the Grand Rapids-based office furniture company. As a consumer-focused visionary in the office furniture industry, Hackett is credited with guiding Steelcase to becoming a global leader. During his 30 years there, he helped transform the office furniture company from traditional manufacturer to industry innovator. Having spent his career focused on the evolving needs of consumers, Hackett is recognized for predicting that the office landscape would shift away from cubicles to an open space environment, giving employees the flexibility to work where they want. He was interim director of athletics at the University of Michigan from October 31, 2014 to March 11, 2016 where he led the search for a permanent athletic director appointed in January 2016. He played center on the University of Michigan football team prior to graduating from the university with a bachelor’s degree in 1977. Mitchell E. Daniels, Jr. is the 12th president of Purdue University and the former governor of Indiana. He was elected Indiana’s 49th governor in 2004 in his first bid for any elected office, and then re-elected in 2008 with more votes than any governor in the state\u27s history. During his tenure, Indiana went from bankruptcy to a AAA credit rating, led the nation in infrastructure building, and passed sweeping ethics and healthcare reforms. After a series of transformations, which included the biggest tax cut in state history, the nation’s most sweeping deregulation of the telecommunications industry and a host of other reforms aimed at strengthening the state’s economy, Indiana’s business climate is now rated among the nation’s best. At Purdue, Daniels has prioritized student affordability and reinvestment in the university’s strengths. Breaking with a 36-year trend, Purdue has held tuition unchanged from 2012 through at least the 2019-20 academic year. Simultaneously, room rates have remained steady, meal plan rates have fallen 10 percent, and student borrowing has dropped 31 percent while investments in student success and STEM research have undergone unprecedented growth. It is less expensive to attend Purdue today than it was in 2012, even without adjusting for inflation. In recognition of his leadership as both a governor and a university president, Daniels was named among the Top 50 World Leaders by Fortune Magazine in March 2015. Prior to becoming governor, Daniels served as chief of staff to Senator Richard Lugar, senior advisor to President Ronald Reagan, and Director of the Office of Management and Budget under President George W. Bush. He also was the CEO of the Hudson Institute, a major contract research organization. During an 11-year career at Eli Lilly and Company, he held a number of top executive posts including president of Eli Lilly’s North American pharmaceutical operations. Daniels earned a bachelor\u27s degree from Princeton’s Woodrow Wilson School of Public and International Affairs and a law degree from Georgetown. He is the author of three books and a contributing columnist in the Washington Post, and his writings are regularly featured in other publications
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