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Timing and Type of Breast Reconstruction in Young Breast Cancer Patients
Breast reconstruction is a significant component in the final recovery of young breast cancer patients, who have a longer lifetime after breast cancer treatment, and aesthetic outcome is a main contributor to their quality of life. The appropriate timing and type of breast reconstruction are considerations in young as well as in older breast cancer patient. The choice of the best breast reconstruction is based on oncological needs, surgeon’s advice and patient’s desire and should always be discussed in a multidisciplinary setting. Breast reconstruction can be performed as an immediate procedure, at the time of mastectomy, or as a delayed procedure, after adjuvant chemotherapy and/or radiotherapy. The young breast cancer patient has usually a wider choice of breast reconstruction techniques and is often more demanding and well informed compared to her older counterparts. In general, there are two types of breast reconstruction: autologous reconstruction requiring that tissue coming from the same patient (i.e. free or pedicled flaps) is utilised to reconstruct the breast; implant-based reconstruction implying that a prosthesis (i.e. expander or implants with or without biologic and synthetic meshes) is used to rebuild the breast volume. Radiotherapy plays an important role in choosing the type and timing of breast reconstruction and should always be evaluated in the multidisciplinary meeting in order to discuss all the alternatives to offer the patient
Breast cancer special issue
The key to diagnosis of Paget disease (PD) is a high index of suspicion. Paget disease should be strongly considered when any areolar or nipple lesion fails to heal with topical steroid therapy. • Inflammatory breast cancer (IBC) is a clinical diagnosis. Identification of warning signs and clinical symptoms is crucial to prompt diagnosis and appropriate referral. • Occult primary breast carcinoma (OPBC) should be differentiated from lymphoma or non-breast metastatic disease. • The most frequent non-epithelial breast malignancies, even if they are rare, are grade III phyllodes tumour, angiosarcoma and primary breast lymphoma.
Future Directions. Within breast oncology, Paget disease, inflammatory breast cancer and occult primary breast cancer should be considered orphan diseases for the heterogeneity of their immunohistochemical profiles and controversial treatments. These diseases affect very few patients, information is as well scarce, and therefore treatment can be difficult to plan. Nowadays, research is moving first meaningful footsteps toward these so far neglected diseases
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